| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Quinestrol perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Quinestrol_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.316657 |
| LMO7 | LIM domain 7 | 0.190708 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.175886 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.119842 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0976069 |
| MYO1E | myosin IE | 0.0912951 |
| MED13 | mediator complex subunit 13 | 0.0837455 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.076972 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0708693 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0695655 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0664028 |
| AREG | amphiregulin | 0.0631295 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0617436 |
| CALR | calreticulin | 0.0599927 |
| TXNIP | thioredoxin interacting protein | 0.0592929 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0588406 |
| ITGA6 | integrin, alpha 6 | 0.0587677 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0567411 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0552392 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0544688 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0515297 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0507099 |
| MYO5B | myosin VB | 0.0502163 |
| SVIL | supervillin | 0.0498409 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.048442 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0483314 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0482268 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0476988 |
| NEBL | nebulette | 0.0469571 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0469503 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0460568 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0435724 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0431997 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0427813 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0418892 |
| SPAG9 | sperm associated antigen 9 | 0.0401575 |
| FBXO11 | F-box protein 11 | 0.039901 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0393134 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0383293 |
| ASPH | aspartate beta-hydroxylase | 0.0382712 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0381719 |
| FAT1 | FAT atypical cadherin 1 | 0.0374884 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0350204 |
| JAK1 | Janus kinase 1 | 0.0348899 |
| ANXA1 | annexin A1 | 0.0342847 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0338831 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0338309 |
| PARD3 | par-3 family cell polarity regulator | 0.033492 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0325158 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0323838 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0323245 |
| SIK3 | SIK family kinase 3 | 0.0322648 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0322556 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0318472 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0312666 |
| PDZD8 | PDZ domain containing 8 | 0.0309145 |
| EGFR | epidermal growth factor receptor | 0.0300995 |
| CTBP2 | C-terminal binding protein 2 | 0.0299378 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.029467 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0292303 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0289776 |
| MUC13 | mucin 13, cell surface associated | 0.0288153 |
| USP53 | ubiquitin specific peptidase 53 | 0.0287919 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.028124 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0281052 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0279666 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0279232 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0279222 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0275893 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0275225 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0273862 |
| RORA | RAR-related orphan receptor A | 0.027219 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0269062 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0266297 |
| HYOU1 | hypoxia up-regulated 1 | 0.0264224 |
| JMJD1C | jumonji domain containing 1C | 0.0261812 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0260428 |
| EMP1 | epithelial membrane protein 1 | 0.0260361 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0260282 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0256883 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0255843 |
| CANX | calnexin | 0.0255796 |
| INTS6 | integrator complex subunit 6 | 0.0251466 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0250748 |
| SQSTM1 | sequestosome 1 | 0.0249381 |
| UBN2 | ubinuclein 2 | 0.0249348 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0248846 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0247371 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.0246415 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.024463 |
| VMP1 | vacuole membrane protein 1 | 0.0244489 |
| FOXO1 | forkhead box O1 | 0.0244368 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0243337 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0243232 |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) | 0.0239868 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0239722 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0239532 |
| TJP2 | tight junction protein 2 | 0.0239478 |
| KLF6 | Kruppel-like factor 6 | 0.0238277 |
| ANKRD17 | ankyrin repeat domain 17 | 0.023747 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.21475 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.126402 |
| TNS4 | tensin 4 | -0.115916 |
| ANXA2 | annexin A2 | -0.114819 |
| PTMA | prothymosin, alpha | -0.112418 |
| TMSB10 | thymosin beta 10 | -0.0908227 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.089095 |
| KRT8 | keratin 8, type II | -0.0765725 |
| GPHN | gephyrin | -0.0723226 |
| RNF43 | ring finger protein 43 | -0.070766 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0697709 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0695964 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0684875 |
| TPM4 | tropomyosin 4 | -0.0604279 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0599045 |
| ONECUT3 | one cut homeobox 3 | -0.05982 |
| PKM | pyruvate kinase, muscle | -0.0589431 |
| FERMT1 | fermitin family member 1 | -0.0556074 |
| ACTN4 | actinin, alpha 4 | -0.0538309 |
| KIF5B | kinesin family member 5B | -0.05339 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0530286 |
| FLNB | filamin B, beta | -0.0525263 |
| CALB1 | calbindin 1, 28kDa | -0.0523692 |
| ITGB4 | integrin, beta 4 | -0.0497483 |
| RPS24 | ribosomal protein S24 | -0.0480191 |
| RPS6 | ribosomal protein S6 | -0.0476921 |
| PIGR | polymeric immunoglobulin receptor | -0.046002 |
| FOSL1 | FOS-like antigen 1 | -0.0440636 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0412671 |
| S100A6 | S100 calcium binding protein A6 | -0.0401202 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0397765 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0393724 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0387979 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0381191 |
| PRSS3 | protease, serine, 3 | -0.038116 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.037872 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0378227 |
| PERP | PERP, TP53 apoptosis effector | -0.0375495 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0374567 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0363122 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.035557 |
| MUC17 | mucin 17, cell surface associated | -0.035334 |
| INSIG1 | insulin induced gene 1 | -0.0351446 |
| HMGA1 | high mobility group AT-hook 1 | -0.033786 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0334112 |
| PATJ | PATJ crumbs cell polarity complex component | -0.033363 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0333267 |
| VCL | vinculin | -0.0325432 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0319023 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0313633 |
| EPHA2 | EPH receptor A2 | -0.0311959 |
| EREG | epiregulin | -0.0306592 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | -0.0302792 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0301534 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0301221 |
| H1-0 | H1.0 linker histone | -0.0296245 |
| RPLP1 | ribosomal protein, large, P1 | -0.02936 |
| POTEF | POTE ankyrin domain family, member F | -0.0287549 |
| GPA33 | glycoprotein A33 (transmembrane) | -0.0283062 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.02823 |
| NDRG1 | N-myc downstream regulated 1 | -0.0279468 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0278335 |
| AHNAK | AHNAK nucleoprotein | -0.0277486 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0268541 |
| FRMD5 | FERM domain containing 5 | -0.0260004 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.025998 |
| RPL23 | ribosomal protein L23 | -0.0256585 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | -0.0255125 |
| TMEM45B | transmembrane protein 45B | -0.025342 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | -0.0253171 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0250392 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0250014 |
| EPCAM | epithelial cell adhesion molecule | -0.0248792 |
| NFIA | nuclear factor I/A | -0.0247526 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0247085 |
| RPL4 | ribosomal protein L4 | -0.0246955 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0246111 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0246007 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0243939 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0243888 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0243601 |
| MATR3 | matrin 3 | -0.0243376 |
| PRELID2 | PRELI domain containing 2 | -0.0237992 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.023783 |
| BCL2L1 | BCL2-like 1 | -0.0237001 |
| GNAS | GNAS complex locus | -0.023552 |
| TXNRD1 | thioredoxin reductase 1 | -0.0235404 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0235385 |
| RACK1 | receptor for activated C kinase 1 | -0.0234794 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0234326 |
| RESF1 | retroelement silencing factor 1 | -0.0233976 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0233754 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0231342 |
| TFRC | transferrin receptor | -0.0231137 |
| RIN2 | Ras and Rab interactor 2 | -0.0229898 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0229787 |
| RPL35A | ribosomal protein L35a | -0.0229191 |
| LDLR | low density lipoprotein receptor | -0.0228096 |
| PCDHB16 | protocadherin beta 16 | -0.0225602 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0223247 |
