| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Quinestrol perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Quinestrol_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.244966 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.132228 |
| CAPRIN2 | caprin family member 2 | 0.115039 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.10022 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0903626 |
| FMNL2 | formin-like 2 | 0.0899278 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0869069 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0805067 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0770229 |
| SPAG9 | sperm associated antigen 9 | 0.0758894 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0688323 |
| RPS12 | ribosomal protein S12 | 0.0648811 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0630821 |
| TXNIP | thioredoxin interacting protein | 0.0618586 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0571125 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0558962 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0546934 |
| RPS8 | ribosomal protein S8 | 0.0523426 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0512785 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0502901 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0502546 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0491446 |
| CD44 | CD44 molecule (Indian blood group) | 0.0481713 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0480799 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0475678 |
| HLA-B | major histocompatibility complex, class I, B | 0.0472116 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0453054 |
| RPL26 | ribosomal protein L26 | 0.0450929 |
| RUNX1 | runt-related transcription factor 1 | 0.0442429 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0432539 |
| SQSTM1 | sequestosome 1 | 0.0396901 |
| SLK | STE20-like kinase | 0.039226 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0388341 |
| PTK2 | protein tyrosine kinase 2 | 0.0383497 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0382038 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.038155 |
| CADM2 | cell adhesion molecule 2 | 0.0375913 |
| VCL | vinculin | 0.0372808 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0370978 |
| RPL12 | ribosomal protein L12 | 0.0367386 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0363753 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0359236 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0350755 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0344467 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0338495 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0332438 |
| RPS3 | ribosomal protein S3 | 0.0322684 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0321197 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0318706 |
| TPM3 | tropomyosin 3 | 0.0317343 |
| CANX | calnexin | 0.031642 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0308334 |
| INTS6 | integrator complex subunit 6 | 0.030294 |
| JMJD1C | jumonji domain containing 1C | 0.0301282 |
| EFNA5 | ephrin-A5 | 0.0300308 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.029798 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0295941 |
| RPS10 | ribosomal protein S10 | 0.0295376 |
| HDAC9 | histone deacetylase 9 | 0.0293982 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0293549 |
| RPL37A | ribosomal protein L37a | 0.0289595 |
| FNIP1 | folliculin interacting protein 1 | 0.0283364 |
| PRELID2 | PRELI domain containing 2 | 0.0283174 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0280502 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0279347 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0278769 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0275221 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.027232 |
| PDE8A | phosphodiesterase 8A | 0.0270376 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0269762 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0269362 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0267991 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0267687 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0267676 |
| JUN | jun proto-oncogene | 0.0263114 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0261712 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.026068 |
| CALR | calreticulin | 0.0258814 |
| PRKCE | protein kinase C, epsilon | 0.0253845 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0250036 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0248553 |
| ASPH | aspartate beta-hydroxylase | 0.0247842 |
| HLA-A | major histocompatibility complex, class I, A | 0.0245357 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0243645 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0243253 |
| GOLGB1 | golgin B1 | 0.0241588 |
| MYOF | myoferlin | 0.023994 |
| UBAP2 | ubiquitin associated protein 2 | 0.0235944 |
| LYST | lysosomal trafficking regulator | 0.0234005 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.023273 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0229328 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0229056 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0227288 |
| CALU | calumenin | 0.022531 |
| B2M | beta-2-microglobulin | 0.0224384 |
| PDE10A | phosphodiesterase 10A | 0.0219387 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0216529 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0215977 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0215682 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0215352 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.231741 |
| VIM | vimentin | -0.197571 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.179804 |
| TXNRD1 | thioredoxin reductase 1 | -0.125557 |
| POTEF | POTE ankyrin domain family, member F | -0.100642 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0851325 |
| EGR1 | early growth response 1 | -0.0819283 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0770638 |
| MT2A | metallothionein 2A | -0.0618043 |
| MKI67 | marker of proliferation Ki-67 | -0.0594166 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.056133 |
| RAI1 | retinoic acid induced 1 | -0.0522337 |
| CENPF | centromere protein F, 350/400kDa | -0.0513768 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0486329 |
| RPLP1 | ribosomal protein, large, P1 | -0.0455191 |
| ACTG1 | actin gamma 1 | -0.044933 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.043572 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0425446 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0412831 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0401486 |
| TMSB4X | thymosin beta 4, X-linked | -0.0396023 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0370602 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0364445 |
| FTL | ferritin, light polypeptide | -0.0363911 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0360474 |
| BMERB1 | bMERB domain containing 1 | -0.0357553 |
| TMEM41B | transmembrane protein 41B | -0.0329749 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0322945 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0313323 |
| EHBP1 | EH domain binding protein 1 | -0.0313266 |
| SRGN | serglycin | -0.0312674 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0309331 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0304779 |
| TAPBP | TAP binding protein (tapasin) | -0.0298261 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0295702 |
| UPP1 | uridine phosphorylase 1 | -0.0290143 |
| DIAPH3 | diaphanous-related formin 3 | -0.0276733 |
| AHNAK | AHNAK nucleoprotein | -0.0266083 |
| PTMA | prothymosin, alpha | -0.0260261 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0254893 |
| MATR3 | matrin 3 | -0.0240546 |
| POM121C | POM121 transmembrane nucleoporin C | -0.02397 |
| RPL31 | ribosomal protein L31 | -0.0237961 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0235828 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0234354 |
| PKM | pyruvate kinase, muscle | -0.022548 |
| RPS4X | ribosomal protein S4, X-linked | -0.0225019 |
| S100A10 | S100 calcium binding protein A10 | -0.0223124 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0218442 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0217479 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.021536 |
| FERMT1 | fermitin family member 1 | -0.0214785 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0212273 |
| RPS24 | ribosomal protein S24 | -0.021025 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -0.0207573 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0202831 |
| FLNB | filamin B, beta | -0.0201532 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0201158 |
| KIF18B | kinesin family member 18B | -0.0199339 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0196863 |
| SGO2 | shugoshin 2 | -0.0196309 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0195148 |
| RPS20 | ribosomal protein S20 | -0.0192825 |
| RPL4 | ribosomal protein L4 | -0.0192614 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0188654 |
| KIF14 | kinesin family member 14 | -0.0187118 |
| HJURP | Holliday junction recognition protein | -0.0186623 |
| HMGB1 | high mobility group box 1 | -0.0186415 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0185316 |
| TUBB | tubulin, beta class I | -0.0184595 |
| EZR | ezrin | -0.0183836 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0180591 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0179796 |
| PRRC2A | proline-rich coiled-coil 2A | -0.0178645 |
| WDR26 | WD repeat domain 26 | -0.0177762 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0176021 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.017592 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0175776 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0174862 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.017395 |
| CDCP1 | CUB domain containing protein 1 | -0.0172873 |
| GRAMD2B | GRAM domain containing 2B | -0.0171049 |
| POM121 | POM121 transmembrane nucleoporin | -0.0170129 |
| CBX3 | chromobox homolog 3 | -0.0168908 |
| ZNF217 | zinc finger protein 217 | -0.0168681 |
| BSG | basigin (Ok blood group) | -0.0168068 |
| FOSL1 | FOS-like antigen 1 | -0.016724 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0166834 |
| MYADM | myeloid-associated differentiation marker | -0.0166267 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0165314 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0162715 |
| SMAD3 | SMAD family member 3 | -0.016226 |
| RGS4 | regulator of G-protein signaling 4 | -0.0162054 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0162035 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0161947 |
| TOP1 | topoisomerase (DNA) I | -0.0161686 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0161027 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0158825 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0158303 |
| PRDX1 | peroxiredoxin 1 | -0.0157113 |
