| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Quinestrol perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Quinestrol_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0983185 |
| NTN4 | netrin 4 | 0.0936578 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0913289 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0830311 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0772371 |
| GLCCI1 | glucocorticoid induced 1 | 0.0771267 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0736061 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0726159 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0666339 |
| RAB1A | RAB1A, member RAS oncogene family | 0.064189 |
| HMGA2 | high mobility group AT-hook 2 | 0.064004 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0588731 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0576503 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0538796 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0535395 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0522012 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0516788 |
| PARD3 | par-3 family cell polarity regulator | 0.0507776 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0498564 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0486146 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0485298 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0479781 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0448131 |
| RBM39 | RNA binding motif protein 39 | 0.0445599 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0427338 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0424872 |
| SMAD3 | SMAD family member 3 | 0.0410863 |
| INTS6 | integrator complex subunit 6 | 0.0408779 |
| CANX | calnexin | 0.0404299 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0399781 |
| CD44 | CD44 molecule (Indian blood group) | 0.0399021 |
| STC1 | stanniocalcin 1 | 0.0394618 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0386767 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0386695 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.037878 |
| WLS | wntless Wnt ligand secretion mediator | 0.0353872 |
| KYNU | kynureninase | 0.0350982 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0335964 |
| RAI14 | retinoic acid induced 14 | 0.0335594 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.033441 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0318729 |
| ADD3 | adducin 3 (gamma) | 0.0307207 |
| SIK3 | SIK family kinase 3 | 0.0305461 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.030481 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0304059 |
| GOLGA4 | golgin A4 | 0.0299179 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0296371 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0292542 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0289403 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0285078 |
| OGA | O-GlcNAcase | 0.0284933 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0284528 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0278294 |
| USP3 | ubiquitin specific peptidase 3 | 0.0278147 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0276838 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0275284 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0274731 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0274194 |
| VRK2 | vaccinia related kinase 2 | 0.0272999 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0265851 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0264842 |
| RPLP0 | ribosomal protein, large, P0 | 0.0261323 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0260753 |
| ERBIN | erbb2 interacting protein | 0.0260382 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.0259371 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0259165 |
| SPAG9 | sperm associated antigen 9 | 0.0257877 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.025739 |
| TGFB1 | transforming growth factor, beta 1 | 0.0255935 |
| USP15 | ubiquitin specific peptidase 15 | 0.0254339 |
| AOPEP | aminopeptidase O (putative) | 0.0251046 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0249797 |
| RUNX2 | runt-related transcription factor 2 | 0.0246748 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0245722 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0244062 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0240413 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0239396 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0237751 |
| AVIL | advillin | 0.0235618 |
| PAPOLA | poly(A) polymerase alpha | 0.0234957 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0228005 |
| STK38L | serine/threonine kinase 38 like | 0.0227875 |
| MED13 | mediator complex subunit 13 | 0.0227775 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0226361 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0224476 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0223963 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0222307 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0220309 |
| FNIP2 | folliculin interacting protein 2 | 0.0219097 |
| FHIT | fragile histidine triad | 0.0215394 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.021527 |
| CDC73 | cell division cycle 73 | 0.0214838 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0214619 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.021338 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0212684 |
| MEF2A | myocyte enhancer factor 2A | 0.0210816 |
| PRELID2 | PRELI domain containing 2 | 0.0209096 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0209081 |
| YME1L1 | YME1-like 1 ATPase | 0.0208759 |
| DUSP16 | dual specificity phosphatase 16 | 0.0207387 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.138505 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.131022 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.129096 |
| MT2A | metallothionein 2A | -0.127244 |
| TMSB10 | thymosin beta 10 | -0.0879272 |
| PCBP2 | poly(rC) binding protein 2 | -0.0868658 |
| FN1 | fibronectin 1 | -0.075899 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0754783 |
| MTSS1 | metastasis suppressor 1 | -0.0724406 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.071878 |
| VIM | vimentin | -0.0706513 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0596338 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0595173 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0594455 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0558304 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0534149 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0527234 |
| POTEF | POTE ankyrin domain family, member F | -0.0517937 |
| DPYD | dihydropyrimidine dehydrogenase | -0.050191 |
| NDRG1 | N-myc downstream regulated 1 | -0.0500786 |
| USP34 | ubiquitin specific peptidase 34 | -0.0493458 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0449759 |
| CDH13 | cadherin 13 | -0.0440116 |
| EGFR | epidermal growth factor receptor | -0.0422105 |
| EGR1 | early growth response 1 | -0.0417422 |
| UBC | ubiquitin C | -0.0417262 |
| CDCP1 | CUB domain containing protein 1 | -0.0411124 |
| PKM | pyruvate kinase, muscle | -0.0408206 |
| TMEM165 | transmembrane protein 165 | -0.0383738 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0381929 |
| HMGA1 | high mobility group AT-hook 1 | -0.0378317 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0359259 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0356973 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.033663 |
| RPS19 | ribosomal protein S19 | -0.0334434 |
| ETV6 | ets variant 6 | -0.0309242 |
| NAV3 | neuron navigator 3 | -0.0306811 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0305231 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.03044 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0304014 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0303164 |
| DTNA | dystrobrevin, alpha | -0.0297107 |
| VEGFA | vascular endothelial growth factor A | -0.0296904 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.029441 |
| RPL23 | ribosomal protein L23 | -0.0289546 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0286067 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0285806 |
| CDK6 | cyclin-dependent kinase 6 | -0.0284041 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0269727 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0266546 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0266363 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0265287 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0263825 |
| PTEN | phosphatase and tensin homolog | -0.0263423 |
| FTL | ferritin, light polypeptide | -0.0253704 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0251738 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0251352 |
| ANGPTL4 | angiopoietin-like 4 | -0.0244701 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0244173 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.024392 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.024377 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.02437 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0240321 |
| ZNF292 | zinc finger protein 292 | -0.0238493 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0237637 |
| LRRC8C | leucine rich repeat containing 8 family, member C | -0.0233509 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0230587 |
| MCL1 | myeloid cell leukemia 1 | -0.0230514 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0228636 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0228404 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0224149 |
| DNER | delta/notch-like EGF repeat containing | -0.0212742 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0211806 |
| TNS3 | tensin 3 | -0.0210528 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0207617 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0206763 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0204645 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.0203998 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0203549 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0203518 |
| DIAPH2 | diaphanous-related formin 2 | -0.0202738 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0201762 |
| TRIM25 | tripartite motif containing 25 | -0.0201253 |
| PRRX1 | paired related homeobox 1 | -0.0199142 |
| RPL28 | ribosomal protein L28 | -0.0193912 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0192661 |
| TXNRD1 | thioredoxin reductase 1 | -0.0190676 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0190662 |
| FRMD4A | FERM domain containing 4A | -0.0188577 |
| RPL3 | ribosomal protein L3 | -0.0188286 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0187128 |
| SLFN5 | schlafen family member 5 | -0.0184743 |
| CDK19 | cyclin-dependent kinase 19 | -0.0184035 |
| RNF149 | ring finger protein 149 | -0.0183939 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.018381 |
| PTK2 | protein tyrosine kinase 2 | -0.0183058 |
| KLF6 | Kruppel-like factor 6 | -0.0181592 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0181229 |
| FAM120A | family with sequence similarity 120A | -0.0179364 |
| MECOM | MDS1 and EVI1 complex locus | -0.0179272 |
