| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Quinestrol perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Quinestrol_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GDA | guanine deaminase | 0.225055 |
| PM20D1 | peptidase M20 domain containing 1 | 0.181961 |
| DST | dystonin | 0.147018 |
| PDLIM5 | PDZ and LIM domain 5 | 0.137655 |
| KYNU | kynureninase | 0.121679 |
| PDE10A | phosphodiesterase 10A | 0.0938648 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0938235 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0879591 |
| MYOF | myoferlin | 0.0770108 |
| FMNL2 | formin-like 2 | 0.074099 |
| VCL | vinculin | 0.0740933 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0731465 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0712612 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.069105 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0670204 |
| INTS6 | integrator complex subunit 6 | 0.0666652 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0650771 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0595243 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0571324 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0563911 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0558112 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0538109 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0519564 |
| ATXN1 | ataxin 1 | 0.0513127 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.048184 |
| SMAD2 | SMAD family member 2 | 0.048087 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0479692 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0445599 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0441268 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0428982 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0425342 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.040963 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0403993 |
| NTN4 | netrin 4 | 0.040184 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0363477 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0346819 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0340555 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0336705 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0327767 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0324494 |
| SQSTM1 | sequestosome 1 | 0.0321496 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.032045 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0313557 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0313269 |
| PTEN | phosphatase and tensin homolog | 0.0311144 |
| FAM107B | family with sequence similarity 107, member B | 0.0307728 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.030407 |
| MB21D2 | Mab-21 domain containing 2 | 0.028977 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0288044 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0284846 |
| PRELID2 | PRELI domain containing 2 | 0.0284551 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0284203 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0271151 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0269348 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0266134 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0264689 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0262955 |
| BMP6 | bone morphogenetic protein 6 | 0.0255292 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0251525 |
| FNIP1 | folliculin interacting protein 1 | 0.0250522 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0247784 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0242156 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0234189 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0230209 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.02301 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0228952 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0228924 |
| PRKD3 | protein kinase D3 | 0.0228722 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0227145 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0224342 |
| GLCCI1 | glucocorticoid induced 1 | 0.021978 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0219108 |
| DNER | delta/notch-like EGF repeat containing | 0.02165 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0215642 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0215229 |
| GLCE | glucuronic acid epimerase | 0.0215064 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0214268 |
| NRDC | nardilysin convertase | 0.0212895 |
| PDE7B | phosphodiesterase 7B | 0.0211551 |
| OGA | O-GlcNAcase | 0.0210383 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0210259 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0208788 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0208438 |
| WWOX | WW domain containing oxidoreductase | 0.0202395 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0201714 |
| CUX1 | cut-like homeobox 1 | 0.0201538 |
| JMJD1C | jumonji domain containing 1C | 0.020134 |
| MALT1 | MALT1 paracaspase | 0.0199007 |
| ATXN7 | ataxin 7 | 0.0197688 |
| GRAMD1B | GRAM domain containing 1B | 0.0194795 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0194356 |
| ATAD1 | ATPase family, AAA domain containing 1 | 0.0192999 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0192736 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0192165 |
| ZNF644 | zinc finger protein 644 | 0.0190145 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.018879 |
| SMAD3 | SMAD family member 3 | 0.0188556 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0187685 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0185034 |
| USP53 | ubiquitin specific peptidase 53 | 0.0184916 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.271359 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.161994 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0926626 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0806424 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0786182 |
| TMSB10 | thymosin beta 10 | -0.0763043 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0741808 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0648265 |
| PTMA | prothymosin, alpha | -0.0550064 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0543303 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0536391 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.053141 |
| RPS6 | ribosomal protein S6 | -0.0529856 |
| VIM | vimentin | -0.0462547 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0449855 |
| NCKAP5 | NCK-associated protein 5 | -0.0445888 |
| EFNA5 | ephrin-A5 | -0.044396 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0426007 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0424384 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0419889 |
| RPLP1 | ribosomal protein, large, P1 | -0.0415096 |
| NDRG1 | N-myc downstream regulated 1 | -0.039038 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0376185 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0375524 |
| AUTS2 | autism susceptibility candidate 2 | -0.0366674 |
| MCL1 | myeloid cell leukemia 1 | -0.0358272 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0345646 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0344927 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0337201 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0336095 |
| PYGL | phosphorylase, glycogen, liver | -0.0335668 |
| PKM | pyruvate kinase, muscle | -0.0329181 |
| LAMA5 | laminin, alpha 5 | -0.0327794 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.032605 |
| FTL | ferritin, light polypeptide | -0.0322568 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.0297073 |
| PTGR1 | prostaglandin reductase 1 | -0.0296301 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0296016 |
| B2M | beta-2-microglobulin | -0.0279798 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0275735 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0275474 |
| RPS27 | ribosomal protein S27 | -0.0275129 |
| FAM13A | family with sequence similarity 13, member A | -0.0273796 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0267319 |
| GNAS | GNAS complex locus | -0.0261927 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0257908 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0253291 |
| NRCAM | neuronal cell adhesion molecule | -0.024981 |
| TBXT | T-box transcription factor T | -0.0247972 |
| EGR1 | early growth response 1 | -0.0244671 |
| RGS2 | regulator of G-protein signaling 2 | -0.0244539 |
| S100A6 | S100 calcium binding protein A6 | -0.0243334 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0239076 |
| LAMB1 | laminin, beta 1 | -0.0237865 |
| RPS19 | ribosomal protein S19 | -0.0231124 |
| SRGN | serglycin | -0.0228714 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0227024 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0225475 |
| LSAMP | limbic system-associated membrane protein | -0.0225473 |
| RPL31 | ribosomal protein L31 | -0.0224332 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0222825 |
| RPL3 | ribosomal protein L3 | -0.0221876 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0218675 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0218605 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0216852 |
| RPL35A | ribosomal protein L35a | -0.0215094 |
| BSG | basigin (Ok blood group) | -0.0210015 |
| POTEF | POTE ankyrin domain family, member F | -0.0208817 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0208462 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.020766 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0207294 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0206106 |
| PGK1 | phosphoglycerate kinase 1 | -0.0205568 |
| MT2A | metallothionein 2A | -0.0201165 |
| RPL12 | ribosomal protein L12 | -0.0199496 |
| RPL23 | ribosomal protein L23 | -0.019829 |
| TPM4 | tropomyosin 4 | -0.0195435 |
| RPS14 | ribosomal protein S14 | -0.0193358 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0193227 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0191796 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.018962 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.018945 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0187381 |
| BMERB1 | bMERB domain containing 1 | -0.0186577 |
| RAI1 | retinoic acid induced 1 | -0.0182958 |
| RPS8 | ribosomal protein S8 | -0.0181332 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0181165 |
| HLA-A | major histocompatibility complex, class I, A | -0.0180844 |
| ZNF292 | zinc finger protein 292 | -0.0179884 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0177526 |
| PRSS23 | protease, serine, 23 | -0.0176239 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0173447 |
| RPL34 | ribosomal protein L34 | -0.0171308 |
| SLC16A6 | solute carrier family 16, member 6 | -0.0171256 |
| PFN1 | profilin 1 | -0.0171101 |
| CCDC88A | coiled-coil domain containing 88A | -0.017093 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.0170706 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0170405 |
| ASPH | aspartate beta-hydroxylase | -0.0169981 |
| GPRIN3 | GPRIN family member 3 | -0.0169311 |
