| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Quinestrol perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Quinestrol_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.145308 |
| FN1 | fibronectin 1 | 0.137692 |
| MYO1E | myosin IE | 0.134631 |
| EGFR | epidermal growth factor receptor | 0.132235 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.105804 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.103091 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0989564 |
| PTK2 | protein tyrosine kinase 2 | 0.0898984 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0850597 |
| FAT1 | FAT atypical cadherin 1 | 0.0845229 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0814964 |
| SMYD3 | SET and MYND domain containing 3 | 0.0810893 |
| PARD3 | par-3 family cell polarity regulator | 0.0768571 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0759107 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0749045 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0736513 |
| RPL12 | ribosomal protein L12 | 0.073553 |
| LDHA | lactate dehydrogenase A | 0.0693657 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0627169 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0622086 |
| GPHN | gephyrin | 0.0610439 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0608251 |
| EHBP1 | EH domain binding protein 1 | 0.0607012 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0604007 |
| MED13L | mediator complex subunit 13-like | 0.0591147 |
| SQSTM1 | sequestosome 1 | 0.058967 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0588362 |
| MSI2 | musashi RNA-binding protein 2 | 0.0575414 |
| ERBIN | erbb2 interacting protein | 0.0573852 |
| TMF1 | TATA element modulatory factor 1 | 0.056731 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.056435 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0560635 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0540854 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0538064 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0526118 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0513668 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0508205 |
| RUNX1 | runt-related transcription factor 1 | 0.0497325 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.049725 |
| EFNA5 | ephrin-A5 | 0.0494749 |
| AFDN | afadin, adherens junction formation factor | 0.048715 |
| FLNB | filamin B, beta | 0.0483757 |
| TCF12 | transcription factor 12 | 0.0483074 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0465225 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0457997 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0450013 |
| CDK13 | cyclin-dependent kinase 13 | 0.0442669 |
| GDA | guanine deaminase | 0.0423891 |
| SMAD3 | SMAD family member 3 | 0.0417145 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0417031 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0415207 |
| FNIP1 | folliculin interacting protein 1 | 0.0410904 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.040935 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0402741 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.039552 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0370206 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0358257 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0348111 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0346888 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0345448 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0338038 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0332185 |
| SLTM | SAFB-like, transcription modulator | 0.0331646 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0330276 |
| DST | dystonin | 0.032827 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0323138 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0321533 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0321442 |
| RPS8 | ribosomal protein S8 | 0.0315342 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0314385 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0312859 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0306853 |
| RORA | RAR-related orphan receptor A | 0.0306118 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0303007 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0301775 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0298654 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0295589 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0294381 |
| RPLP1 | ribosomal protein, large, P1 | 0.0294111 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.029048 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.028954 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0286677 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0285778 |
| DENND5B | DENN/MADD domain containing 5B | 0.0283026 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0277406 |
| PRELID2 | PRELI domain containing 2 | 0.0277321 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.027043 |
| RTN4 | reticulon 4 | 0.0264075 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0263886 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0261738 |
| CUL4A | cullin 4A | 0.0258742 |
| CANX | calnexin | 0.0254635 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0251448 |
| ATP9B | ATPase, class II, type 9B | 0.0249246 |
| BBX | bobby sox homolog (Drosophila) | 0.0247925 |
| NDRG1 | N-myc downstream regulated 1 | 0.0242131 |
| CERS6 | ceramide synthase 6 | 0.0233402 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0231369 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0226858 |
| MED13 | mediator complex subunit 13 | 0.0225831 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.235367 |
| FTL | ferritin, light polypeptide | -0.165394 |
| PTMA | prothymosin, alpha | -0.154317 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.148155 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.129944 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.127279 |
| TMSB10 | thymosin beta 10 | -0.107273 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0976917 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0951926 |
| RPL35A | ribosomal protein L35a | -0.0936331 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0885368 |
| VCL | vinculin | -0.0836015 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0776567 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0740649 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0728646 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0683453 |
| POTEF | POTE ankyrin domain family, member F | -0.0672233 |
| GPC6 | glypican 6 | -0.0671642 |
| HDLBP | high density lipoprotein binding protein | -0.0669308 |
| SP100 | SP100 nuclear antigen | -0.0646138 |
| MORF4L2 | mortality factor 4 like 2 | -0.0642825 |
| KIF5B | kinesin family member 5B | -0.0635914 |
| ZNF292 | zinc finger protein 292 | -0.0619276 |
| PRKCA | protein kinase C, alpha | -0.061863 |
| RPL19 | ribosomal protein L19 | -0.0602554 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0600558 |
| RPS24 | ribosomal protein S24 | -0.0600362 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0596922 |
| MT2A | metallothionein 2A | -0.059686 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0569813 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0563943 |
| RPS12 | ribosomal protein S12 | -0.0550878 |
| PDE10A | phosphodiesterase 10A | -0.0539371 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0533322 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0502437 |
| CALR | calreticulin | -0.0493935 |
| MCL1 | myeloid cell leukemia 1 | -0.048713 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0482931 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0476817 |
| PKM | pyruvate kinase, muscle | -0.0436384 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0405756 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0403336 |
| RBM25 | RNA binding motif protein 25 | -0.0397479 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0389519 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0379152 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0373464 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0363286 |
| RPL37A | ribosomal protein L37a | -0.0361954 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0354103 |
| SETD5 | SET domain containing 5 | -0.0347956 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0344425 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0343671 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.034027 |
| TXNIP | thioredoxin interacting protein | -0.033338 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0331654 |
| CCNI | cyclin I | -0.0329875 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0327427 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0301624 |
| GOLGA4 | golgin A4 | -0.0285096 |
| CDH13 | cadherin 13 | -0.0269443 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.026072 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.025091 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0241221 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0233965 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0228448 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0227078 |
| JMJD1C | jumonji domain containing 1C | -0.0221996 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0203293 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0202077 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0200266 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0199349 |
| TOP1 | topoisomerase (DNA) I | -0.0187832 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0176906 |
| NBAS | neuroblastoma amplified sequence | -0.0172434 |
| COPA | coatomer protein complex, subunit alpha | -0.0166215 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0152391 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0141786 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0140089 |
| TLK1 | tousled-like kinase 1 | -0.0133881 |
| TXNRD1 | thioredoxin reductase 1 | -0.0125475 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0123876 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0120039 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0111528 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0102823 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0088742 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.00856301 |
| SYAP1 | synapse associated protein 1 | -0.00848118 |
| PGK1 | phosphoglycerate kinase 1 | -0.00824851 |
| LSAMP | limbic system-associated membrane protein | -0.00793069 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00785393 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.00785307 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | -0.0074278 |
| ANKRD12 | ankyrin repeat domain 12 | -0.00727384 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.00705102 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.00701912 |
| RPS19 | ribosomal protein S19 | -0.00681781 |
| LMNA | lamin A/C | -0.00586605 |
| PCNX4 | pecanex 4 | -0.00567219 |
| RPS6 | ribosomal protein S6 | -0.00561164 |
| ENO1 | enolase 1, (alpha) | -0.00545288 |
