| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Quinestrol perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Quinestrol_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0774833 |
| HMGA2 | high mobility group AT-hook 2 | 0.0608943 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0599216 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0566608 |
| INTS6 | integrator complex subunit 6 | 0.0563614 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0540966 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0507744 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0494795 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0492434 |
| SQSTM1 | sequestosome 1 | 0.0471308 |
| DST | dystonin | 0.0459008 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0442367 |
| POTEF | POTE ankyrin domain family, member F | 0.0440582 |
| EGFR | epidermal growth factor receptor | 0.0437445 |
| PRKCA | protein kinase C, alpha | 0.0424571 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0423286 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0413961 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0413938 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0411563 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0406295 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0382214 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0380658 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0377877 |
| RUNX1 | runt-related transcription factor 1 | 0.0367127 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0362513 |
| SVIL | supervillin | 0.0360625 |
| ATXN1 | ataxin 1 | 0.0359049 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0358311 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0354494 |
| JAK1 | Janus kinase 1 | 0.035346 |
| FN1 | fibronectin 1 | 0.03369 |
| FAM168A | family with sequence similarity 168, member A | 0.0335104 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0333837 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0331448 |
| FOXO3 | forkhead box O3 | 0.0321263 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0318125 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0306674 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0303406 |
| OGA | O-GlcNAcase | 0.0303011 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0302754 |
| PCED1B | PC-esterase domain containing 1B | 0.0300588 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0290326 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0286765 |
| PRR16 | proline rich 16 | 0.0284684 |
| CLIC4 | chloride intracellular channel 4 | 0.0282354 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0281685 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.027888 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0274653 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0274396 |
| FLNA | filamin A, alpha | 0.0273833 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0272073 |
| PURA | purine-rich element binding protein A | 0.0271646 |
| DTNA | dystrobrevin, alpha | 0.0267632 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0266775 |
| RBM6 | RNA binding motif protein 6 | 0.0265739 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0264903 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0263746 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0255969 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0255658 |
| LMO7 | LIM domain 7 | 0.0255597 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0251964 |
| TAOK1 | TAO kinase 1 | 0.0250238 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0246613 |
| PER1 | period circadian clock 1 | 0.0246421 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0243679 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0242234 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0241917 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0241424 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0237428 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0236265 |
| TAGLN2 | transgelin 2 | 0.0234334 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0231155 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0231075 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0230247 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0228733 |
| CAVIN1 | caveolae associated protein 1 | 0.0227479 |
| KLF6 | Kruppel-like factor 6 | 0.0226497 |
| JUND | jun D proto-oncogene | 0.0223083 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0222561 |
| MRTFA | myocardin related transcription factor A | 0.0218815 |
| TRAM2 | translocation associated membrane protein 2 | 0.0217928 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0217568 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0217133 |
| SHPRH | SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase | 0.0216484 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0215872 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.020977 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0209242 |
| JUN | jun proto-oncogene | 0.020924 |
| PODXL | podocalyxin-like | 0.0209007 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.0207805 |
| COL5A1 | collagen, type V, alpha 1 | 0.0205992 |
| TLE4 | transducin-like enhancer of split 4 | 0.0205682 |
| TPI1 | triosephosphate isomerase 1 | 0.0204969 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0204145 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0203636 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0203188 |
| RSF1 | remodeling and spacing factor 1 | 0.0203159 |
| CYTH1 | cytohesin 1 | 0.0202374 |
| KAT2B | K(lysine) acetyltransferase 2B | 0.0202216 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0200756 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.104742 |
| TMSB10 | thymosin beta 10 | -0.0899917 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0761459 |
| ZNF292 | zinc finger protein 292 | -0.0718307 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0666884 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0665964 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0640191 |
| OSMR | oncostatin M receptor | -0.0629214 |
| SMYD3 | SET and MYND domain containing 3 | -0.062433 |
| LDHA | lactate dehydrogenase A | -0.0616109 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0606491 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0586535 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0533261 |
| RPL4 | ribosomal protein L4 | -0.0528847 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0513657 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0467044 |
| FAF2 | Fas associated factor family member 2 | -0.0458967 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0425963 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0420657 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0405195 |
| RBM39 | RNA binding motif protein 39 | -0.0402539 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.039097 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0390108 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0384861 |
| KIAA1328 | KIAA1328 | -0.0382385 |
| RPL23 | ribosomal protein L23 | -0.0378618 |
| NUP98 | nucleoporin 98kDa | -0.0371727 |
| DNER | delta/notch-like EGF repeat containing | -0.0367383 |
| ECT2 | epithelial cell transforming 2 | -0.0367285 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0365607 |
| RAD51B | RAD51 paralog B | -0.0363393 |
| CDCP1 | CUB domain containing protein 1 | -0.0361689 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0356631 |
| PHF3 | PHD finger protein 3 | -0.0348065 |
| YAP1 | Yes-associated protein 1 | -0.0348012 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.034779 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0347567 |
| TCERG1 | transcription elongation regulator 1 | -0.0346063 |
| SEPTIN2 | septin 2 | -0.0344625 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.0342112 |
| NOP58 | NOP58 ribonucleoprotein | -0.0341455 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0340497 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0338961 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.033861 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0338458 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0337988 |
| CENPP | centromere protein P | -0.0331967 |
| RPL30 | ribosomal protein L30 | -0.0330099 |
| PRPF8 | pre-mRNA processing factor 8 | -0.0326023 |
| BSG | basigin (Ok blood group) | -0.0325981 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0325463 |
| MATR3 | matrin 3 | -0.0325261 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0322819 |
| XPO1 | exportin 1 | -0.0322421 |
| TLK1 | tousled-like kinase 1 | -0.0320706 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0320596 |
| TPX2 | TPX2, microtubule-associated | -0.0320467 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.031986 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0319704 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0319395 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0315283 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0314053 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0309313 |
| RPL37 | ribosomal protein L37 | -0.0309092 |
| AHNAK | AHNAK nucleoprotein | -0.0309043 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.030876 |
| ATG7 | autophagy related 7 | -0.0303344 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0301346 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0299421 |
| ZBTB44 | zinc finger and BTB domain containing 44 | -0.0297694 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0297329 |
| CENPF | centromere protein F, 350/400kDa | -0.0290954 |
| TMEM123 | transmembrane protein 123 | -0.0290004 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0289975 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0289277 |
| PAPOLA | poly(A) polymerase alpha | -0.0288526 |
| YBX1 | Y box binding protein 1 | -0.0287369 |
| HJURP | Holliday junction recognition protein | -0.0286958 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0286278 |
| GNAS | GNAS complex locus | -0.028603 |
| RRBP1 | ribosome binding protein 1 | -0.028601 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0284599 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0282092 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0281398 |
| NMT1 | N-myristoyltransferase 1 | -0.0281033 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.02798 |
| TPM4 | tropomyosin 4 | -0.0279367 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0278995 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0277978 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0274878 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0274199 |
| RBM25 | RNA binding motif protein 25 | -0.0273106 |
| RPLP1 | ribosomal protein, large, P1 | -0.0271582 |
| RPS20 | ribosomal protein S20 | -0.026966 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0269646 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0269095 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0265745 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0265707 |
| ATM | ATM serine/threonine kinase | -0.0264914 |
| RACGAP1 | Rac GTPase activating protein 1 | -0.0264283 |
