| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the R-atenolol-2496 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABHD6 | abhydrolase domain containing 6 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ADCY9 | adenylate cyclase 9 |
| ADGRL2 | adhesion G protein-coupled receptor L2 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| AQP1 | aquaporin 1 (Colton blood group) |
| ATF7 | activating transcription factor 7 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAPN9 | calpain 9 |
| CFAP69 | cilia and flagella associated protein 69 |
| CKM | creatine kinase, muscle |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CREM | cAMP responsive element modulator |
| CRHR1 | corticotropin releasing hormone receptor 1 |
| CYTH1 | cytohesin 1 |
| DFNB31 | deafness, autosomal recessive 31 |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DNASE2B | deoxyribonuclease II beta |
| DRD5 | dopamine receptor D5 |
| EDNRA | endothelin receptor type A |
| EFNA5 | ephrin-A5 |
| ELL | elongation factor RNA polymerase II |
| FBXO2 | F-box protein 2 |
| FER | fer (fps/fes related) tyrosine kinase |
| FLOT1 | flotillin 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GATA3 | GATA binding protein 3 |
| GCH1 | GTP cyclohydrolase 1 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GPC1 | glypican 1 |
| HIC2 | hypermethylated in cancer 2 |
| HOXA4 | homeobox A4 |
| HPCAL4 | hippocalcin like 4 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled |
| INE1 | inactivation escape 1 (non-protein coding) |
| IQCK | IQ motif containing K |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA0226L | KIAA0226-like |
| KIF1A | kinesin family member 1A |
| KIF3A | kinesin family member 3A |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLK1 | kallikrein 1 |
| KSR1 | kinase suppressor of ras 1 |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| LINC00652 | long intergenic non-protein coding RNA 652 |
| MAU2 | MAU2 sister chromatid cohesion factor |
| METTL7A | methyltransferase like 7A |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MT3 | metallothionein 3 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NRP2 | neuropilin 2 |
| PDE8B | phosphodiesterase 8B |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| RAB11B | RAB11B, member RAS oncogene family |
| RANBP1 | RAN binding protein 1 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SH2D1A | SH2 domain containing 1A |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLAMF7 | SLAM family member 7 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SRPX | sushi-repeat containing protein, X-linked |
| SSH3 | slingshot protein phosphatase 3 |
| SSTR4 | somatostatin receptor 4 |
| STX2 | syntaxin 2 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCF3 | transcription factor 3 |
| THSD7A | thrombospondin, type I, domain containing 7A |
| TMPRSS15 | transmembrane protease, serine 15 |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 |
| TP53TG1 | TP53 target 1 (non-protein coding) |
| TPMT | thiopurine S-methyltransferase |
| TTC38 | tetratricopeptide repeat domain 38 |
| TXNRD3 | thioredoxin reductase 3 |
| WSCD1 | WSC domain containing 1 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZNF154 | zinc finger protein 154 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| ZNF76 | zinc finger protein 76 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| ZXDB | zinc finger, X-linked, duplicated B |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ACP6 | acid phosphatase 6, lysophosphatidic |
| ADGRE1 | adhesion G protein-coupled receptor E1 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| AMDHD2 | amidohydrolase domain containing 2 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ASPN | asporin |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BNC2 | basonuclin 2 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| CCDC69 | coiled-coil domain containing 69 |
| CCDC9 | coiled-coil domain containing 9 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| COQ6 | coenzyme Q6 monooxygenase |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DNM3 | dynamin 3 |
| DNMBP | dynamin binding protein |
| DOK5 | docking protein 5 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EFNA3 | ephrin-A3 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM131A | family with sequence similarity 131, member A |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FBXO31 | F-box protein 31 |
| FKBPL | FK506 binding protein like |
| FLT4 | fms-related tyrosine kinase 4 |
| FMOD | fibromodulin |
| GALK1 | galactokinase 1 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPR85 | G protein-coupled receptor 85 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HIST1H4E | histone cluster 1, H4e |
| HRH2 | histamine receptor H2 |
| ICAM5 | intercellular adhesion molecule 5, telencephalin |
| IFI6 | interferon, alpha-inducible protein 6 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| JMJD4 | jumonji domain containing 4 |
| KIAA1024 | KIAA1024 |
| KPTN | kaptin (actin binding protein) |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MDM4 | MDM4, p53 regulator |
| MED22 | mediator complex subunit 22 |
| MLPH | melanophilin |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PNOC | prepronociceptin |
| POLL | polymerase (DNA directed), lambda |
| PQLC2 | PQ loop repeat containing 2 |
| PRMT7 | protein arginine methyltransferase 7 |
| PROS1 | protein S (alpha) |
| PYGB | phosphorylase, glycogen; brain |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| S100A12 | S100 calcium binding protein A12 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SPATS2 | spermatogenesis associated, serine-rich 2 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM115 | transmembrane protein 115 |
| TMEM209 | transmembrane protein 209 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| TRIM36 | tripartite motif containing 36 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TUBA4B | tubulin, alpha 4b |
| UCN | urocortin |
| USP19 | ubiquitin specific peptidase 19 |
| VASH1 | vasohibin 1 |
| ZNF225 | zinc finger protein 225 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |