R-atenolol-2855 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the R-atenolol-2855 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
APC adenomatous polyposis coli
APLP2 amyloid beta (A4) precursor-like protein 2
ARHGAP35 Rho GTPase activating protein 35
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATF5 activating transcription factor 5
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BIN1 bridging integrator 1
CD58 CD58 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CNPY4 canopy FGF signaling regulator 4
COL7A1 collagen, type VII, alpha 1
CRHR1 corticotropin releasing hormone receptor 1
DACH1 dachshund family transcription factor 1
DAPK2 death-associated protein kinase 2
DIO2 deiodinase, iodothyronine, type II
DMXL2 Dmx-like 2
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DSTYK dual serine/threonine and tyrosine protein kinase
ECE1 endothelin converting enzyme 1
EHBP1L1 EH domain binding protein 1-like 1
EIF1 eukaryotic translation initiation factor 1
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELSPBP1 epididymal sperm binding protein 1
EML2 echinoderm microtubule associated protein like 2
ESR1 estrogen receptor 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FGFR1 fibroblast growth factor receptor 1
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GREB1 growth regulation by estrogen in breast cancer 1
GRIK5 glutamate receptor, ionotropic, kainate 5
GSN gelsolin
HFE hemochromatosis
HLA-G major histocompatibility complex, class I, G
IDS iduronate 2-sulfatase
IFT22 intraflagellar transport 22
IL6ST interleukin 6 signal transducer
IQSEC2 IQ motif and Sec7 domain 2
IRS2 insulin receptor substrate 2
ITGB4 integrin, beta 4
KHK ketohexokinase (fructokinase)
KLF9 Kruppel-like factor 9
KLHL28 kelch-like family member 28
LAT2 linker for activation of T cells family, member 2
LMNB1 lamin B1
LOC257152 uncharacterized LOC257152
LOXL3 lysyl oxidase-like 3
MAOB monoamine oxidase B
MED18 mediator complex subunit 18
MEIS2 Meis homeobox 2
METTL7A methyltransferase like 7A
NEFL neurofilament, light polypeptide
NME5 NME/NM23 family member 5
NPIPB15 nuclear pore complex interacting protein family, member B15
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OVOL2 ovo-like zinc finger 2
PCDHB12 protocadherin beta 12
PDCD6 programmed cell death 6
PIEZO2 piezo-type mechanosensitive ion channel component 2
PMEL premelanosome protein
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PRR14L proline rich 14-like
RABGAP1 RAB GTPase activating protein 1
RAD51 RAD51 recombinase
RBM19 RNA binding motif protein 19
RND1 Rho family GTPase 1
RPL7 ribosomal protein L7
RWDD3 RWD domain containing 3
SFXN3 sideroflexin 3
SMC4 structural maintenance of chromosomes 4
SOX9 SRY (sex determining region Y)-box 9
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STK17B serine/threonine kinase 17b
TDRD3 tudor domain containing 3
THAP9 THAP domain containing 9
TMC6 transmembrane channel-like 6
TMEM53 transmembrane protein 53
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBQLN4 ubiquilin 4
USP36 ubiquitin specific peptidase 36
VAV2 vav 2 guanine nucleotide exchange factor
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEGFA vascular endothelial growth factor A
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZC3H7B zinc finger CCCH-type containing 7B
ZFP36L1 ZFP36 ring finger protein-like 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF287 zinc finger protein 287
ZNF423 zinc finger protein 423
ZNF493 zinc finger protein 493
ZNF652 zinc finger protein 652
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARC activity-regulated cytoskeleton-associated protein
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF79 chromosome 14 open reading frame 79
C1ORF159 chromosome 1 open reading frame 159
CALCOCO1 calcium binding and coiled-coil domain 1
CAMTA2 calmodulin binding transcription activator 2
CCDC121 coiled-coil domain containing 121
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CHKB choline kinase beta
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCN2 chloride channel, voltage-sensitive 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DBR1 debranching RNA lariats 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEAF1 DEAF1 transcription factor
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EGFL7 EGF-like-domain, multiple 7
ERCC6 excision repair cross-complementation group 6
FAM184A family with sequence similarity 184, member A
FAM46C family with sequence similarity 46, member C
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FOSL1 FOS-like antigen 1
FOXI1 forkhead box I1
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
HIST1H2BO histone cluster 1, H2bo
HOXA4 homeobox A4
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFT140 intraflagellar transport 140
IFT81 intraflagellar transport 81
IGFBP6 insulin-like growth factor binding protein 6
IL4R interleukin 4 receptor
INF2 inverted formin, FH2 and WH2 domain containing
IPO8 importin 8
IRF1 interferon regulatory factor 1
ITPKB inositol-trisphosphate 3-kinase B
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIF13B kinesin family member 13B
KLF2 Kruppel-like factor 2
KLHL25 kelch-like family member 25
KLK5 kallikrein-related peptidase 5
KRT24 keratin 24, type I
LHX6 LIM homeobox 6
LRRC20 leucine rich repeat containing 20
LRRC37A2 leucine rich repeat containing 37, member A2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MRPL41 mitochondrial ribosomal protein L41
NACA2 nascent polypeptide-associated complex alpha subunit 2
NEIL3 nei endonuclease VIII-like 3 (E. coli)
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OSGIN1 oxidative stress induced growth inhibitor 1
OTUD3 OTU deubiquitinase 3
PACS1 phosphofurin acidic cluster sorting protein 1
PARP12 poly (ADP-ribose) polymerase family, member 12
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G3 phospholipase A2, group III
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RFXAP regulatory factor X-associated protein
RIN2 Ras and Rab interactor 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPL23AP32 ribosomal protein L23a pseudogene 32
SCNN1B sodium channel, non voltage gated 1 beta subunit
SDC3 syndecan 3
SETD8 SET domain containing (lysine methyltransferase) 8
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPON2 spondin 2, extracellular matrix protein
ST5 suppression of tumorigenicity 5
STARD3 StAR-related lipid transfer (START) domain containing 3
STARD5 StAR-related lipid transfer (START) domain containing 5
SYNC syncoilin, intermediate filament protein
TET3 tet methylcytosine dioxygenase 3
TFF2 trefoil factor 2
TLN1 talin 1
TMEM180 transmembrane protein 180
TMEM62 transmembrane protein 62
TNS2 tensin 2
TRIM36 tripartite motif containing 36
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VEGFB vascular endothelial growth factor B
WDR33 WD repeat domain 33
ZFP36 ZFP36 ring finger protein
ZNF219 zinc finger protein 219
ZNF350 zinc finger protein 350
ZNF551 zinc finger protein 551
ZNF552 zinc finger protein 552
ZNF639 zinc finger protein 639
ZNF816 zinc finger protein 816