RAB6A Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description RAB6A, member RAS oncogene family|This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 5870)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAB6A
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Genes

67 co-expressed genes for RAB6A from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABR active BCR-related
AFG3L2 AFG3-like AAA ATPase 2
AHCYL1 adenosylhomocysteinase-like 1
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
ARF3 ADP-ribosylation factor 3
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ATG12 autophagy related 12
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
ATXN2 ataxin 2
BCAP31 B-cell receptor-associated protein 31
CANX calnexin
CLSTN1 calsyntenin 1
CLTA clathrin, light chain A
COPS5 COP9 signalosome subunit 5
CS citrate synthase
CTDNEP1 CTD nuclear envelope phosphatase 1
DCTN2 dynactin 2 (p50)
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
ENSA endosulfine alpha
F8A1 coagulation factor VIII-associated 1
FAM120A family with sequence similarity 120A
FBXW11 F-box and WD repeat domain containing 11
GLB1 galactosidase, beta 1
GPAA1 glycosylphosphatidylinositol anchor attachment 1
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
LYPLA1 lysophospholipase I
MDH1 malate dehydrogenase 1, NAD (soluble)
METAP1 methionyl aminopeptidase 1
MRPL9 mitochondrial ribosomal protein L9
MTA1 metastasis associated 1
MTDH metadherin
MYL12B myosin, light chain 12B, regulatory
NONO non-POU domain containing, octamer-binding
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PHF3 PHD finger protein 3
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
RAB1A RAB1A, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RTN4 reticulon 4
SART3 squamous cell carcinoma antigen recognized by T cells 3
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SEC24C SEC24 family member C
SERP1 stress-associated endoplasmic reticulum protein 1
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SP3 Sp3 transcription factor
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
STARD7 StAR-related lipid transfer (START) domain containing 7
SUMO1 small ubiquitin-like modifier 1
TCEA1 transcription elongation factor A (SII), 1
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMED2 transmembrane emp24 domain trafficking protein 2
TRAPPC3 trafficking protein particle complex 3
TUG1 taurine up-regulated 1 (non-protein coding)
VGLL4 vestigial-like family member 4
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
WBP2 WW domain binding protein 2
XPO7 exportin 7