RAC1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)|The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 5879)
External Link https://ncbi.nlm.nih.gov/gene/5879
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Genes

499 genes differentially expressed following the RAC1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
BAMBI BMP and activin membrane-bound inhibitor 0.010861
MMP7 matrix metallopeptidase 7 0.00846916
HSPA1A heat shock 70kDa protein 1A 0.00745748
PBX1 pre-B-cell leukemia homeobox 1 0.00703147
S100A8 S100 calcium binding protein A8 0.00696108
GPM6B glycoprotein M6B 0.00677717
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00647706
TIMP1 TIMP metallopeptidase inhibitor 1 0.00588411
XIC X chromosome inactivation center 0.00561128
FCGBP Fc fragment of IgG binding protein 0.00559854
AQP3 aquaporin 3 (Gill blood group) 0.00552284
CTBP2 C-terminal binding protein 2 0.00530353
APOD apolipoprotein D 0.00526968
TRIB2 tribbles pseudokinase 2 0.00526677
IRS2 insulin receptor substrate 2 0.00523706
MLPH melanophilin 0.00523474
PRUNE2 prune homolog 2 (Drosophila) 0.00520279
IFI27 interferon, alpha-inducible protein 27 0.00518167
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 0.00515672
SPRED2 sprouty-related, EVH1 domain containing 2 0.00514104
WDR7 WD repeat domain 7 0.00508984
HIST1H2BD histone cluster 1, H2bd 0.00504623
SORBS1 sorbin and SH3 domain containing 1 0.00501028
NPAS2 neuronal PAS domain protein 2 0.00500593
MEN1 multiple endocrine neoplasia I 0.00498144
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00495403
LXN latexin 0.00495074
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00490632
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.00489748
CA12 carbonic anhydrase XII 0.00488572
KRT13 keratin 13, type I 0.0048629
ADD3 adducin 3 (gamma) 0.00482332
AMIGO2 adhesion molecule with Ig-like domain 2 0.0048069
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00477281
CRELD2 cysteine-rich with EGF-like domains 2 0.00469841
DENND2D DENN/MADD domain containing 2D 0.00468401
ITM2C integral membrane protein 2C 0.00464899
C14ORF132 chromosome 14 open reading frame 132 0.00464446
MAOB monoamine oxidase B 0.00463254
SLPI secretory leukocyte peptidase inhibitor 0.00462919
NLGN4X neuroligin 4, X-linked 0.00461934
CLU clusterin 0.00460088
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.00458925
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00452353
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.00451863
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00446725
GREB1 growth regulation by estrogen in breast cancer 1 0.00446569
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.0044571
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00443684
NRCAM neuronal cell adhesion molecule 0.00443636
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00443402
TSPO translocator protein (18kDa) 0.00442294
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00441449
TSC22D1 TSC22 domain family, member 1 0.00439879
IL7R interleukin 7 receptor 0.00438838
SCG5 secretogranin V 0.00438569
HSPB1 heat shock 27kDa protein 1 0.00438193
SCGB2A1 secretoglobin, family 2A, member 1 0.00438137
LMBRD1 LMBR1 domain containing 1 0.00437653
KRT19 keratin 19, type I 0.00436177
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00435012
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.00433696
CSRP1 cysteine and glycine-rich protein 1 0.00432794
PDGFRL platelet-derived growth factor receptor-like 0.00431502
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00430418
TUBA1A tubulin, alpha 1a 0.00428992
PNRC1 proline-rich nuclear receptor coactivator 1 0.00428958
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00427299
DLK1 delta-like 1 homolog (Drosophila) 0.00425909
L1CAM L1 cell adhesion molecule 0.00425217
CLDN3 claudin 3 0.00423433
AKR1C3 aldo-keto reductase family 1, member C3 0.0042174
STK10 serine/threonine kinase 10 0.00420809
TDP2 tyrosyl-DNA phosphodiesterase 2 0.0042019
CRABP2 cellular retinoic acid binding protein 2 0.00419785
KYNU kynureninase 0.00419692
QPRT quinolinate phosphoribosyltransferase 0.00419459
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00419358
ISG20 interferon stimulated exonuclease gene 20kDa 0.00419089
HTRA1 HtrA serine peptidase 1 0.00418523
BHLHE41 basic helix-loop-helix family, member e41 0.00412885
VLDLR very low density lipoprotein receptor 0.00411185
OLFM1 olfactomedin 1 0.00408557
PLIN2 perilipin 2 0.0040802
COQ8A coenzyme Q8A 0.00406591
PDE8B phosphodiesterase 8B 0.00405895
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00404704
CYBA cytochrome b-245, alpha polypeptide 0.00403894
C1ORF115 chromosome 1 open reading frame 115 0.00403217
CRYBG1 crystallin beta-gamma domain containing 1 0.00401847
GUSB glucuronidase, beta 0.00400654
FXYD3 FXYD domain containing ion transport regulator 3 0.00396052
REG3A regenerating islet-derived 3 alpha 0.00395781
MB myoglobin 0.00395099
PDLIM3 PDZ and LIM domain 3 0.00391593
H1-2 H1.2 linker histone, cluster member 0.00389617
MEIS2 Meis homeobox 2 0.00388459
TRAF3IP2 TRAF3 interacting protein 2 0.00385135
NSG1 neuron specific gene family member 1 0.00385009
MVP major vault protein 0.00384147
CRABP1 cellular retinoic acid binding protein 1 0.00383628
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.00383031
ISYNA1 inositol-3-phosphate synthase 1 0.00381547
KLF5 Kruppel-like factor 5 (intestinal) 0.00381523
FAIM Fas apoptotic inhibitory molecule 0.00381416
C7 complement component 7 0.00379848
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.00379227
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.00376839
LINC00623 long intergenic non-protein coding RNA 623 0.00375165
NPTX2 neuronal pentraxin II 0.00375152
HSPA2 heat shock 70kDa protein 2 0.00371375
GPRC5B G protein-coupled receptor, class C, group 5, member B 0.00370902
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.00369825
BAX BCL2-associated X protein 0.00368636
HIST1H2AC histone cluster 1, H2ac 0.0036847
CDK19 cyclin-dependent kinase 19 0.0036841
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00367035
UBA1 ubiquitin-like modifier activating enzyme 1 0.00366857
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00366173
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00365787
FLOT1 flotillin 1 0.00364887
AKR1C2 aldo-keto reductase family 1, member C2 0.00364417
SLC16A4 solute carrier family 16, member 4 0.00362655
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.00361709
CYRIA CYFIP related Rac1 interactor A 0.00360629
PIR pirin (iron-binding nuclear protein) 0.00357651
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00356555
BTG1 B-cell translocation gene 1, anti-proliferative 0.0035627
GNAS GNAS complex locus 0.0035543
PON2 paraoxonase 2 0.00354906
NPY1R neuropeptide Y receptor Y1 0.00354307
EHD3 EH-domain containing 3 0.00353457
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.00352568
MDK midkine (neurite growth-promoting factor 2) 0.00352408
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 0.00351923
VWA5A von Willebrand factor A domain containing 5A 0.00349903
BTG2 BTG family, member 2 0.00349522
DENND1B DENN/MADD domain containing 1B 0.00347953
USP11 ubiquitin specific peptidase 11 0.00347561
MSRB2 methionine sulfoxide reductase B2 0.00347096
PTEN phosphatase and tensin homolog 0.0034694
RAP1GAP RAP1 GTPase activating protein 0.00346093
NRIP1 nuclear receptor interacting protein 1 0.00345541
NKX2-2 NK2 homeobox 2 0.0034482
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 0.00344818
ELF1 E74-like factor 1 (ets domain transcription factor) 0.00344513
RAB29 RAB29, member RAS oncogene family 0.00344348
MREG melanoregulin 0.00342955
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 0.00341427
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00341162
AUTS2 autism susceptibility candidate 2 0.00341161
PADI2 peptidyl arginine deiminase, type II 0.00340646
JADE3 jade family PHD finger 3 0.00340176
SELENBP1 selenium binding protein 1 0.00340144
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0033986
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.00337701
TST thiosulfate sulfurtransferase (rhodanese) 0.0033711
MFGE8 milk fat globule-EGF factor 8 protein 0.00336093
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.00335197
ADAMDEC1 ADAM-like, decysin 1 0.0033517
FABP7 fatty acid binding protein 7, brain 0.00335059
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 0.00334019
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 0.00333588
SLC22A18 solute carrier family 22, member 18 0.00333127
PFKM phosphofructokinase, muscle 0.00332976
SST somatostatin 0.00332264
SPRR3 small proline-rich protein 3 0.00331841
NEBL nebulette 0.00331048
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00330875
HECA headcase homolog (Drosophila) 0.00329474
IPO13 importin 13 0.00329273
C8ORF4 chromosome 8 open reading frame 4 0.00329178
SP110 SP110 nuclear body protein 0.00328793
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.0032811
DCHS1 dachsous cadherin-related 1 0.00327559
BDH2 3-hydroxybutyrate dehydrogenase, type 2 0.00327538
BTK Bruton agammaglobulinemia tyrosine kinase 0.00327272
CAST calpastatin 0.00326827
SWAP70 SWAP switching B-cell complex 70kDa subunit 0.00326261
YPEL5 yippee-like 5 (Drosophila) 0.00324878
MYBPC1 myosin binding protein C, slow type 0.00324597
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00324474
HIST1H2AE histone cluster 1, H2ae 0.00323579
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00323345
FKBP11 FK506 binding protein 11, 19 kDa 0.00323243
MPDZ multiple PDZ domain protein 0.0032304
CASP1 caspase 1, apoptosis-related cysteine peptidase 0.00322407
STX8 syntaxin 8 0.00321638
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 0.00321634
DDIT4 DNA-damage-inducible transcript 4 0.00321314
SVIL supervillin 0.00321173
MME membrane metallo-endopeptidase 0.00320911
TLK2 tousled-like kinase 2 0.00320646
HLA-DRA major histocompatibility complex, class II, DR alpha 0.00320272
ELF5 E74-like factor 5 (ets domain transcription factor) 0.00320059
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00318758
TLR4 toll-like receptor 4 0.00318681
MAGED2 melanoma antigen family D2 0.00318632
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.00318132
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00317114
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.00316829
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00316665
MAOA monoamine oxidase A 0.00316547
LUM lumican 0.00316112
CARMIL1 capping protein regulator and myosin 1 linker 1 0.00315073
G6PD glucose-6-phosphate dehydrogenase 0.00315027
HNMT histamine N-methyltransferase 0.00314351
DGKZ diacylglycerol kinase, zeta 0.00314176
TCEAL2 transcription elongation factor A (SII)-like 2 0.00313972
DEFA5 defensin, alpha 5, Paneth cell-specific 0.00311626
MGP matrix Gla protein 0.00311388
OLFM4 olfactomedin 4 0.00309827
GPM6A glycoprotein M6A 0.00309528
CNR1 cannabinoid receptor 1 (brain) 0.00309235
ZFP36L1 ZFP36 ring finger protein-like 1 0.00308589
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00308459
AKR1C1 aldo-keto reductase family 1, member C1 0.00307879
TLE5 TLE family member 5, transcriptional modulator 0.00307237
RAB13 RAB13, member RAS oncogene family 0.00306351
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00305167
LY75 lymphocyte antigen 75 0.00305163
SHTN1 shootin 1 0.00305129
CTSF cathepsin F 0.00304286
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00304143
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00303987
INSM1 insulinoma-associated 1 0.00303912
CD58 CD58 molecule 0.00303231
RHOC ras homolog family member C 0.00303211
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.00303041
LRP4 low density lipoprotein receptor-related protein 4 0.00303028
BCL2A1 BCL2-related protein A1 0.00302841
GAS1 growth arrest-specific 1 0.00302532
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.00302532
TXNIP thioredoxin interacting protein 0.00301661
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00301484
DUSP3 dual specificity phosphatase 3 0.00301094
ACADVL acyl-CoA dehydrogenase, very long chain 0.00300898
FLOT2 flotillin 2 0.00300627
DDR2 discoidin domain receptor tyrosine kinase 2 0.00299627
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00299482
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.00299479
RGS19 regulator of G-protein signaling 19 0.00297262
ZNF423 zinc finger protein 423 0.00297015
GSPT2 G1 to S phase transition 2 0.00296489
MCTP1 multiple C2 domains, transmembrane 1 0.00296365
ZHX2 zinc fingers and homeoboxes 2 0.00295942
CXCL6 chemokine (C-X-C motif) ligand 6 0.00295673
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.00295589
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.0029551
GSTZ1 glutathione S-transferase zeta 1 0.00295047

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00718442
RGCC regulator of cell cycle -0.00689233
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00688773
CA2 carbonic anhydrase II -0.00669895
G0S2 G0/G1 switch 2 -0.00616794
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00609207
INHBA inhibin, beta A -0.00591294
ODC1 ornithine decarboxylase 1 -0.00583839
SIRT3 sirtuin 3 -0.00572338
FST follistatin -0.00564063
OXA1L oxidase (cytochrome c) assembly 1-like -0.00523521
ANXA5 annexin A5 -0.00521079
NPM3 nucleophosmin/nucleoplasmin 3 -0.00513425
ZEB1 zinc finger E-box binding homeobox 1 -0.00512491
CXCL2 chemokine (C-X-C motif) ligand 2 -0.00504636
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -0.00501976
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00496517
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.0049619
RIOX2 ribosomal oxygenase 2 -0.004809
HHEX hematopoietically expressed homeobox -0.00477724
CCN2 cellular communication network factor 2 -0.00475428
TSPAN5 tetraspanin 5 -0.00472455
SPATS2L spermatogenesis associated, serine-rich 2-like -0.00468197
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00463374
ITGA6 integrin, alpha 6 -0.00459171
APOA2 apolipoprotein A-II -0.00447016
CD69 CD69 molecule -0.00445236
STC2 stanniocalcin 2 -0.00439372
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00434972
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0043383
CNN3 calponin 3, acidic -0.00433246
ANOS1 anosmin 1 -0.00431844
TYMS thymidylate synthetase -0.00430374
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00429399
CST6 cystatin E/M -0.00425552
HSPA4L heat shock 70kDa protein 4-like -0.00422903
DSE dermatan sulfate epimerase -0.00422652
CCL4 chemokine (C-C motif) ligand 4 -0.00419485
OSBPL3 oxysterol binding protein-like 3 -0.00418017
TUBB6 tubulin, beta 6 class V -0.00417154
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00416964
VSNL1 visinin-like 1 -0.0041029
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.0040773
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00407114
SDC2 syndecan 2 -0.00405243
CTSV cathepsin V -0.00404847
IL1B interleukin 1, beta -0.00402891
FGFR1 fibroblast growth factor receptor 1 -0.00402156
KDM5D lysine (K)-specific demethylase 5D -0.00401458
TGFBI transforming growth factor, beta-induced, 68kDa -0.00400935
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00400875
AHSG alpha-2-HS-glycoprotein -0.00400284
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -0.00399826
ADM adrenomedullin -0.00398123
DYNLL1 dynein, light chain, LC8-type 1 -0.00397084
SLBP stem-loop binding protein -0.00395779
PHACTR2 phosphatase and actin regulator 2 -0.00393014
PRPS1 phosphoribosyl pyrophosphate synthetase 1 -0.00391654
PXDN peroxidasin -0.0039013
ARL4A ADP-ribosylation factor-like 4A -0.00390058
RHOA ras homolog family member A -0.00389582
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00389385
COTL1 coactosin-like F-actin binding protein 1 -0.00388561
SH3BP4 SH3-domain binding protein 4 -0.00386066
LOXL2 lysyl oxidase-like 2 -0.00378324
COL5A1 collagen, type V, alpha 1 -0.00376518
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00373646
MMP1 matrix metallopeptidase 1 -0.00373573
FOSL1 FOS-like antigen 1 -0.00373416
EREG epiregulin -0.00373035
HOXB6 homeobox B6 -0.00372814
LOX lysyl oxidase -0.00372486
CCP110 centriolar coiled coil protein 110kDa -0.00369064
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00366549
MIR22HG MIR22 host gene -0.00364763
HP haptoglobin -0.00363365
GADD45G growth arrest and DNA-damage-inducible, gamma -0.00362956
MXRA7 matrix-remodelling associated 7 -0.00362776
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -0.00362712
RANBP1 RAN binding protein 1 -0.00362593
FOXD1 forkhead box D1 -0.00361548
NPR3 natriuretic peptide receptor 3 -0.00359184
RGS2 regulator of G-protein signaling 2 -0.0035915
CLGN calmegin -0.00357963
FAM216A family with sequence similarity 216, member A -0.00354977
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00352775
CCNA2 cyclin A2 -0.00352609
ACTA2 actin, alpha 2, smooth muscle, aorta -0.0035235
ACOT7 acyl-CoA thioesterase 7 -0.00351938
NR4A2 nuclear receptor subfamily 4, group A, member 2 -0.00351469
ZNF211 zinc finger protein 211 -0.00351433
NUSAP1 nucleolar and spindle associated protein 1 -0.00351055
LRRC59 leucine rich repeat containing 59 -0.00350867
PLS3 plastin 3 -0.00349124
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.00348846
CCDC86 coiled-coil domain containing 86 -0.00347396
PLK2 polo-like kinase 2 -0.00346199
ORM1 orosomucoid 1 -0.00345907
STOM stomatin -0.00345806
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -0.00345046
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -0.00344941
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.00344292
OSR2 odd-skipped related transciption factor 2 -0.00344131
C5ORF28 chromosome 5 open reading frame 28 -0.00343563
UBE2N ubiquitin-conjugating enzyme E2N -0.00343476
RPA3 replication protein A3, 14kDa -0.0034266
ACO1 aconitase 1, soluble -0.00340648
ZBTB18 zinc finger and BTB domain containing 18 -0.00340155
HIGD1A HIG1 hypoxia inducible domain family, member 1A -0.00339221
CDCA4 cell division cycle associated 4 -0.00338145
PRMT5 protein arginine methyltransferase 5 -0.00337384
BIRC5 baculoviral IAP repeat containing 5 -0.00335877
POSTN periostin, osteoblast specific factor -0.00335731
PLAU plasminogen activator, urokinase -0.00335379
BGN biglycan -0.00334302
THAP9-AS1 THAP9 antisense RNA 1 -0.00332526
GRPEL1 GrpE-like 1, mitochondrial (E. coli) -0.00331885
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.00331018
ELN elastin -0.00328497
SRP72 signal recognition particle 72kDa -0.00328205
NAV3 neuron navigator 3 -0.00327393
MET MET proto-oncogene, receptor tyrosine kinase -0.00326432
SRM spermidine synthase -0.00326246
F2R coagulation factor II (thrombin) receptor -0.00326106
CDKN3 cyclin-dependent kinase inhibitor 3 -0.00325709
PCP4 Purkinje cell protein 4 -0.00325009
TRAM2 translocation associated membrane protein 2 -0.00324492
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 -0.00322994
RPS5 ribosomal protein S5 -0.00322793
IPO5 importin 5 -0.00322593
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -0.00321733
CRYBG3 beta-gamma crystallin domain containing 3 -0.00321199
FGFR3 fibroblast growth factor receptor 3 -0.00320885
HBEGF heparin-binding EGF-like growth factor -0.0032035
S100A2 S100 calcium binding protein A2 -0.0031926
PHB prohibitin -0.00319106
HOPX HOP homeobox -0.0031747
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 -0.00317469
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.00317237
IFRD2 interferon-related developmental regulator 2 -0.00316589
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00313459
FGF13 fibroblast growth factor 13 -0.00313376
COL11A1 collagen, type XI, alpha 1 -0.00313335
ADRB2 adrenoceptor beta 2, surface -0.00312527
NID2 nidogen 2 (osteonidogen) -0.0031178
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -0.00311085
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -0.00310159
POLR2D polymerase (RNA) II (DNA directed) polypeptide D -0.00307536
C4BPB complement component 4 binding protein, beta -0.00306837
CHPT1 choline phosphotransferase 1 -0.00306367
MED28 mediator complex subunit 28 -0.00305034
IFT57 intraflagellar transport 57 -0.00304876
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -0.0030415
CHP1 calcineurin-like EF-hand protein 1 -0.00304006
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -0.00303736
RACGAP1 Rac GTPase activating protein 1 -0.0030294
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -0.00302443
ARL5A ADP-ribosylation factor-like 5A -0.00300956
PPAT phosphoribosyl pyrophosphate amidotransferase -0.0030079
CETN2 centrin, EF-hand protein, 2 -0.00300729
TFRC transferrin receptor -0.00300585
MORC4 MORC family CW-type zinc finger 4 -0.00299123
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -0.00298252
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -0.00298083
PRPF4 pre-mRNA processing factor 4 -0.00297876
SEPTIN11 septin 11 -0.00297801
TYRP1 tyrosinase-related protein 1 -0.0029651
EGR2 early growth response 2 -0.00296414
APOB apolipoprotein B -0.00296238
CLDND1 claudin domain containing 1 -0.00295649
THAP12 THAP domain containing 12 -0.00294591
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) -0.00294249
LCE2B late cornified envelope 2B -0.00294071
TPSAB1 tryptase alpha/beta 1 -0.00294018
ESM1 endothelial cell-specific molecule 1 -0.00293937
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.00293283
LOXL1 lysyl oxidase-like 1 -0.00293186
LGALS1 lectin, galactoside-binding, soluble, 1 -0.00293
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00292949
TMEM204 transmembrane protein 204 -0.00292858
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -0.00292407
PSAT1 phosphoserine aminotransferase 1 -0.00292038
NCOA4 nuclear receptor coactivator 4 -0.00291917
TACC3 transforming, acidic coiled-coil containing protein 3 -0.00291442
CLDN1 claudin 1 -0.00291359
C9ORF3 chromosome 9 open reading frame 3 -0.00290558
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00290539
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -0.00290235
SUB1 SUB1 homolog (S. cerevisiae) -0.0029007
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.00288982
POLD2 polymerase (DNA directed), delta 2, accessory subunit -0.00288707
CDSN corneodesmosin -0.00288645
ANGPT1 angiopoietin 1 -0.00287113
PGC progastricsin (pepsinogen C) -0.00287074
CTSG cathepsin G -0.00286821
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 -0.00286305
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.00286164
IGHMBP2 immunoglobulin mu binding protein 2 -0.00284735
RFC5 replication factor C (activator 1) 5, 36.5kDa -0.0028429
ZNF551 zinc finger protein 551 -0.00284121
SEH1L SEH1-like (S. cerevisiae) -0.00283322
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) -0.00282074
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.00281144
PPP4R1 protein phosphatase 4, regulatory subunit 1 -0.00280756
DUSP14 dual specificity phosphatase 14 -0.00280547
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00280545
COL15A1 collagen, type XV, alpha 1 -0.0027983
LRRC17 leucine rich repeat containing 17 -0.00279419
COL4A1 collagen, type IV, alpha 1 -0.00278923
F5 coagulation factor V (proaccelerin, labile factor) -0.00278903
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -0.00278576
PNO1 partner of NOB1 homolog (S. cerevisiae) -0.00278351
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 -0.00277801
SDHAF3 succinate dehydrogenase complex assembly factor 3 -0.00277652
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.00277478
SFTPB surfactant protein B -0.00277376
OTUD3 OTU deubiquitinase 3 -0.00276399
BRIX1 BRX1, biogenesis of ribosomes -0.00276103
GSPT1 G1 to S phase transition 1 -0.00275212
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.0027494
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 -0.00274925
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.00274667
APOH apolipoprotein H (beta-2-glycoprotein I) -0.00274552
MDFIC MyoD family inhibitor domain containing -0.00274107
NME1 NME/NM23 nucleoside diphosphate kinase 1 -0.00274084
MICALL1 MICAL-like 1 -0.00273741
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00273688
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 -0.00273622
H2AFV H2A histone family, member V -0.00273105
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00272213
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -0.00272037
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -0.00272005
DCTN3 dynactin 3 (p22) -0.00271971
KCTD5 potassium channel tetramerization domain containing 5 -0.00271712
CNTN1 contactin 1 -0.00271598
LGALS2 lectin, galactoside-binding, soluble, 2 -0.00271254
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00270674
GPX3 glutathione peroxidase 3 -0.00270179
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -0.00269587
GTF2A2 general transcription factor IIA, 2, 12kDa -0.00269586
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.0026942
TUBG1 tubulin, gamma 1 -0.00269253
NREP neuronal regeneration related protein -0.002684
ENOPH1 enolase-phosphatase 1 -0.00268046
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -0.00266599
TMEM38B transmembrane protein 38B -0.00266372
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 -0.00265941
THY1 Thy-1 cell surface antigen -0.00265862
CNPY3 canopy FGF signaling regulator 3 -0.0026569