RAC1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)|The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 5879)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAC1
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Genes

211 co-expressed genes for RAC1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABR active BCR-related
ACTL6A actin-like 6A
ACTN4 actinin, alpha 4
AHCYL1 adenosylhomocysteinase-like 1
ANKRD17 ankyrin repeat domain 17
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
ARCN1 archain 1
ARF3 ADP-ribosylation factor 3
ARF4 ADP-ribosylation factor 4
ARF5 ADP-ribosylation factor 5
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa
ATG12 autophagy related 12
ATOX1 antioxidant 1 copper chaperone
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
ATXN2 ataxin 2
BANF1 barrier to autointegration factor 1
BCAP31 B-cell receptor-associated protein 31
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
BRD8 bromodomain containing 8
C6ORF62 chromosome 6 open reading frame 62
CANX calnexin
CAPZB capping protein (actin filament) muscle Z-line, beta
CDK16 cyclin-dependent kinase 16
CENPB centromere protein B, 80kDa
CFDP1 craniofacial development protein 1
CLN3 ceroid-lipofuscinosis, neuronal 3
CLTC clathrin, heavy chain (Hc)
CNIH1 cornichon family AMPA receptor auxiliary protein 1
CNOT3 CCR4-NOT transcription complex, subunit 3
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
COPS5 COP9 signalosome subunit 5
COPS7A COP9 signalosome subunit 7A
COX5A cytochrome c oxidase subunit Va
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CS citrate synthase
CSNK1G2 casein kinase 1, gamma 2
CSNK2B casein kinase 2, beta polypeptide
CTDNEP1 CTD nuclear envelope phosphatase 1
CYC1 cytochrome c-1
CYCS cytochrome c, somatic
DAP death-associated protein
DCTN2 dynactin 2 (p50)
DDB1 damage-specific DNA binding protein 1, 127kDa
DNPEP aspartyl aminopeptidase
DOCK3 dedicator of cytokinesis 3
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
DRG1 developmentally regulated GTP binding protein 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
EBAG9 estrogen receptor binding site associated, antigen, 9
EI24 etoposide induced 2.4
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
EML2 echinoderm microtubule associated protein like 2
ENSA endosulfine alpha
F8A1 coagulation factor VIII-associated 1
FAM120A family with sequence similarity 120A
FBXW11 F-box and WD repeat domain containing 11
FMR1 fragile X mental retardation 1
FOXK2 forkhead box K2
GANAB glucosidase, alpha; neutral AB
GGCT gamma-glutamylcyclotransferase
GLB1 galactosidase, beta 1
GLG1 golgi glycoprotein 1
GMFB glia maturation factor, beta
GORASP2 golgi reassembly stacking protein 2, 55kDa
GPAA1 glycosylphosphatidylinositol anchor attachment 1
GPX4 glutathione peroxidase 4
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HSPA8 heat shock 70kDa protein 8
HTATSF1 HIV-1 Tat specific factor 1
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
ILVBL ilvB (bacterial acetolactate synthase)-like
ISCU iron-sulfur cluster assembly enzyme
IST1 increased sodium tolerance 1 homolog (yeast)
JTB jumping translocation breakpoint
KARS lysyl-tRNA synthetase
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
LYPLA1 lysophospholipase I
MAML1 mastermind-like 1 (Drosophila)
MAP2K2 mitogen-activated protein kinase kinase 2
MDH1 malate dehydrogenase 1, NAD (soluble)
MEA1 male-enhanced antigen 1
METAP1 methionyl aminopeptidase 1
MORF4L2 mortality factor 4 like 2
MRPL28 mitochondrial ribosomal protein L28
MRPL9 mitochondrial ribosomal protein L9
MRPS18B mitochondrial ribosomal protein S18B
MTA1 metastasis associated 1
MTCP1 mature T-cell proliferation 1
MTDH metadherin
MYL12B myosin, light chain 12B, regulatory
NCBP2 nuclear cap binding protein subunit 2, 20kDa
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NONO non-POU domain containing, octamer-binding
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUP62 nucleoporin 62kDa
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
PARG poly (ADP-ribose) glycohydrolase
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PDAP1 PDGFA associated protein 1
PDCD6 programmed cell death 6
PEX11B peroxisomal biogenesis factor 11 beta
PGRMC1 progesterone receptor membrane component 1
PHF3 PHD finger protein 3
PICALM phosphatidylinositol binding clathrin assembly protein
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PMM2 phosphomannomutase 2
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11
PPP1R7 protein phosphatase 1, regulatory subunit 7
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PPT1 palmitoyl-protein thioesterase 1
PRDX4 peroxiredoxin 4
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PWP1 PWP1 homolog (S. cerevisiae)
RAB1A RAB1A, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD21 RAD21 homolog (S. pombe)
RAD23B RAD23 homolog B (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAN RAN, member RAS oncogene family
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RHEB Ras homolog enriched in brain
RNF4 ring finger protein 4
RPA1 replication protein A1, 70kDa
RTN4 reticulon 4
SARS seryl-tRNA synthetase
SART3 squamous cell carcinoma antigen recognized by T cells 3
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SEC13 SEC13 homolog (S. cerevisiae)
SEC24C SEC24 family member C
SEC61B Sec61 beta subunit
SEC61G Sec61 gamma subunit
SEPHS2 selenophosphate synthetase 2
SERP1 stress-associated endoplasmic reticulum protein 1
SHFM1 split hand/foot malformation (ectrodactyly) type 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SKP1 S-phase kinase-associated protein 1
SLC10A3 solute carrier family 10, member 3
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SMNDC1 survival motor neuron domain containing 1
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNX1 sorting nexin 1
SOD1 superoxide dismutase 1, soluble
SP3 Sp3 transcription factor
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SRP9 signal recognition particle 9kDa
SSR4 signal sequence receptor, delta
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STARD7 StAR-related lipid transfer (START) domain containing 7
STK24 serine/threonine kinase 24
STX4 syntaxin 4
SUMO1 small ubiquitin-like modifier 1
SUMO2 small ubiquitin-like modifier 2
SYPL1 synaptophysin-like 1
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMED2 transmembrane emp24 domain trafficking protein 2
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM106C transmembrane protein 106C
TMEM147 transmembrane protein 147
TRAPPC3 trafficking protein particle complex 3
TSTA3 tissue specific transplantation antigen P35B
TUG1 taurine up-regulated 1 (non-protein coding)
UBA1 ubiquitin-like modifier activating enzyme 1
UBAP2L ubiquitin associated protein 2-like
UBE2A ubiquitin-conjugating enzyme E2A
UBE3C ubiquitin protein ligase E3C
UBR5 ubiquitin protein ligase E3 component n-recognin 5
VGLL4 vestigial-like family member 4
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
WBP2 WW domain binding protein 2
XPC xeroderma pigmentosum, complementation group C
XPO6 exportin 6
XPO7 exportin 7
YIF1A Yip1 interacting factor homolog A (S. cerevisiae)
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZZZ3 zinc finger, ZZ-type containing 3