RAC2 GTPase cycle Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-9013404
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Genes

88 proteins participating in the RAC2 GTPase cycle pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ABI1 abl-interactor 1
ABI2 abl-interactor 2
ABR active BCR-related
ANKLE2 ankyrin repeat and LEM domain containing 2
ARHGAP1 Rho GTPase activating protein 1
ARHGAP17 Rho GTPase activating protein 17
ARHGAP21 Rho GTPase activating protein 21
ARHGAP26 Rho GTPase activating protein 26
ARHGAP32 Rho GTPase activating protein 32
ARHGAP35 Rho GTPase activating protein 35
ARHGAP39 Rho GTPase activating protein 39
ARHGAP42 Rho GTPase activating protein 42
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARMCX3 armadillo repeat containing, X-linked 3
BAIAP2L1 BAI1-associated protein 2-like 1
BCR breakpoint cluster region
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
CAV1 caveolin 1, caveolae protein, 22kDa
CDC42 cell division cycle 42
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYFIP1 cytoplasmic FMR1 interacting protein 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DEPDC1B DEP domain containing 1B
DIAPH3 diaphanous-related formin 3
DOCK1 dedicator of cytokinesis 1
DOCK10 dedicator of cytokinesis 10
DOCK2 dedicator of cytokinesis 2
DOCK3 dedicator of cytokinesis 3
DOCK4 dedicator of cytokinesis 4
DSG2 desmoglein 2
EMD emerin
EPHA2 EPH receptor A2
ERBIN erbb2 interacting protein
ESYT1 extended synaptotagmin-like protein 1
GARRE1 granule associated Rac and RHOG effector 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
IQGAP1 IQ motif containing GTPase activating protein 1
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LBR lamin B receptor
LEMD3 LEM domain containing 3
LMAN1 lectin, mannose-binding, 1
MCAM melanoma cell adhesion molecule
MCF2 MCF.2 cell line derived transforming sequence
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
MTX1 metaxin 1
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NCKAP1 NCK-associated protein 1
NCKAP1L NCK-associated protein 1-like
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies)
OPHN1 oligophrenin 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PGRMC2 progesterone receptor membrane component 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLD2 phospholipase D2
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
RAB7A RAB7A, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RACGAP1 Rac GTPase activating protein 1
SAMM50 SAMM50 sorting and assembly machinery component
SLITRK5 SLIT and NTRK-like family, member 5
STBD1 starch binding domain 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAOK3 TAO kinase 3
TFRC transferrin receptor
TIAM1 T-cell lymphoma invasion and metastasis 1
TMPO thymopoietin
TRIO trio Rho guanine nucleotide exchange factor
VAMP3 vesicle-associated membrane protein 3
VANGL1 VANGL planar cell polarity protein 1
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VRK2 vaccinia related kinase 2
WASF2 WAS protein family, member 2