| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)|The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5881) |
| External Link | https://ncbi.nlm.nih.gov/gene/5881 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the RAC3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.013146 |
| CSTA | cystatin A (stefin A) | 0.0127173 |
| SRGN | serglycin | 0.012257 |
| LXN | latexin | 0.0122557 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0114046 |
| AXL | AXL receptor tyrosine kinase | 0.0113956 |
| AGR2 | anterior gradient 2 | 0.0113585 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0111142 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.0108069 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0105492 |
| ANOS1 | anosmin 1 | 0.00999345 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.009686 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 | 0.00947076 |
| LYZ | lysozyme | 0.00939455 |
| EAPP | E2F-associated phosphoprotein | 0.00920419 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00920288 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00901734 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00877345 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00870551 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00865367 |
| CD302 | CD302 molecule | 0.00859949 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00856236 |
| RGS10 | regulator of G-protein signaling 10 | 0.00854907 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00849538 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00839684 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00838791 |
| CETN2 | centrin, EF-hand protein, 2 | 0.00835518 |
| TMEM14B | transmembrane protein 14B | 0.00830728 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.00828784 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00824434 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00823995 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00823965 |
| COL10A1 | collagen, type X, alpha 1 | 0.00818609 |
| PLN | phospholamban | 0.00817705 |
| DAPK1 | death-associated protein kinase 1 | 0.0081718 |
| CHMP6 | charged multivesicular body protein 6 | 0.00804968 |
| LMCD1 | LIM and cysteine-rich domains 1 | 0.00802155 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.0079253 |
| SORD | sorbitol dehydrogenase | 0.00786607 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00779159 |
| CPVL | carboxypeptidase, vitellogenic-like | 0.00778746 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00776961 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00775913 |
| EVI2A | ecotropic viral integration site 2A | 0.00774945 |
| NVL | nuclear VCP-like | 0.00770868 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00744846 |
| KIF2C | kinesin family member 2C | 0.00740396 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.00735158 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00733579 |
| HBB | hemoglobin, beta | 0.00724303 |
| CLU | clusterin | 0.00723549 |
| KRT7 | keratin 7, type II | 0.0072168 |
| KYNU | kynureninase | 0.00720977 |
| SELL | selectin L | 0.0071952 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.00716963 |
| LY86 | lymphocyte antigen 86 | 0.00715607 |
| TXNDC9 | thioredoxin domain containing 9 | 0.00714318 |
| MNDA | myeloid cell nuclear differentiation antigen | 0.0071387 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00713457 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.007099 |
| PMP22 | peripheral myelin protein 22 | 0.00709568 |
| CD86 | CD86 molecule | 0.00708977 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0070884 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00708012 |
| IL15 | interleukin 15 | 0.00707804 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0070621 |
| VIM | vimentin | 0.00706129 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00705229 |
| METRN | meteorin, glial cell differentiation regulator | 0.00704626 |
| PIR | pirin (iron-binding nuclear protein) | 0.00700782 |
| GALC | galactosylceramidase | 0.00698051 |
| TLR4 | toll-like receptor 4 | 0.00692904 |
| ASPN | asporin | 0.00689284 |
| PTK2 | protein tyrosine kinase 2 | 0.00687269 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.0068269 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.0067697 |
| GTF2H5 | general transcription factor IIH, polypeptide 5 | 0.00675261 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0067319 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00667784 |
| GATA2 | GATA binding protein 2 | 0.00666702 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.00666098 |
| WFDC1 | WAP four-disulfide core domain 1 | 0.00665069 |
| NAAA | N-acylethanolamine acid amidase | 0.00664174 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.00662607 |
| BICC1 | BicC family RNA binding protein 1 | 0.00660245 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.0065946 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 0.0065882 |
| TDP1 | tyrosyl-DNA phosphodiesterase 1 | 0.0065817 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.00657371 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | 0.00655727 |
| THBS1 | thrombospondin 1 | 0.00651956 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.00648941 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | 0.00646766 |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.00645596 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00645125 |
| RNASE6 | ribonuclease, RNase A family, k6 | 0.00642961 |
| EPCAM | epithelial cell adhesion molecule | 0.00641481 |
| NELL2 | NEL-like 2 (chicken) | 0.00639042 |
| RPP40 | ribonuclease P/MRP 40kDa subunit | 0.00638908 |
| CCN2 | cellular communication network factor 2 | 0.00637572 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00635346 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00633825 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00630363 |
| MLF1 | myeloid leukemia factor 1 | 0.00629171 |
| IL7R | interleukin 7 receptor | 0.00628035 |
| VCAN | versican | 0.00627085 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00625842 |
| CLEC4A | C-type lectin domain family 4, member A | 0.00625131 |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.00624898 |
| LST1 | leukocyte specific transcript 1 | 0.00622722 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00621824 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | 0.00621622 |
| RPA2 | replication protein A2, 32kDa | 0.00620313 |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.00619836 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0061848 |
| NNMT | nicotinamide N-methyltransferase | 0.00618387 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.00617883 |
| ASF1A | anti-silencing function 1A histone chaperone | 0.0061706 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) | 0.00613543 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.0061044 |
| C12ORF29 | chromosome 12 open reading frame 29 | 0.00608704 |
| ARL3 | ADP-ribosylation factor-like 3 | 0.00608594 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00608434 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00607958 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00607464 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | 0.00604385 |
| SET | SET nuclear proto-oncogene | 0.00602649 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) | 0.00602628 |
| ERI2 | ERI1 exoribonuclease family member 2 | 0.00601794 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00598384 |
| DSE | dermatan sulfate epimerase | 0.00597526 |
| IQCG | IQ motif containing G | 0.00595741 |
| S100P | S100 calcium binding protein P | 0.00595159 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00591776 |
| SDC1 | syndecan 1 | 0.00588297 |
| GCH1 | GTP cyclohydrolase 1 | 0.00586938 |
| SHCBP1 | SHC SH2-domain binding protein 1 | 0.00586779 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.00586524 |
| CD93 | CD93 molecule | 0.00585201 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.00584968 |
| PIP | prolactin-induced protein | 0.00584527 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00583711 |
| COPS4 | COP9 signalosome subunit 4 | 0.00580424 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.00580368 |
| NEBL | nebulette | 0.00578642 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 0.00578598 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.00578344 |
| NEK4 | NIMA-related kinase 4 | 0.00575323 |
| CDCA4 | cell division cycle associated 4 | 0.00575287 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like | 0.00574022 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00573804 |
| TBXA2R | thromboxane A2 receptor | 0.00572192 |
| FSCN1 | fascin actin-bundling protein 1 | 0.0057175 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00571305 |
| XK | X-linked Kx blood group | 0.00570948 |
| CD48 | CD48 molecule | 0.00569543 |
| GPR65 | G protein-coupled receptor 65 | 0.00568947 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.00565484 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00565145 |
| ABHD10 | abhydrolase domain containing 10 | 0.00564142 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00564093 |
| EIF2S1 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | 0.005634 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00562844 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00562735 |
| TKTL1 | transketolase-like 1 | 0.0056261 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00560595 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.00559844 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00559659 |
| C1ORF115 | chromosome 1 open reading frame 115 | 0.00558846 |
| SLC2A4RG | SLC2A4 regulator | 0.00558111 |
| REXO5 | RNA exonuclease 5 | 0.00557276 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | 0.00557213 |
| THBS2 | thrombospondin 2 | 0.00556826 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00555705 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00555658 |
| MSMB | microseminoprotein, beta- | 0.0055514 |
| TCTN1 | tectonic family member 1 | 0.00554778 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00554442 |
| MYO5C | myosin VC | 0.00553467 |
| WDR61 | WD repeat domain 61 | 0.00552473 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | 0.00551529 |
| LZTFL1 | leucine zipper transcription factor-like 1 | 0.00549934 |
| PRUNE1 | prune exopolyphosphatase 1 | 0.00549802 |
| AHSP | alpha hemoglobin stabilizing protein | 0.00549217 |
| MTARC2 | mitochondrial amidoxime reducing component 2 | 0.00548775 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | 0.00546432 |
| AQP4 | aquaporin 4 | 0.00546213 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.0054594 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00545892 |
| SPART | spartin | 0.00544879 |
| GUCY2C | guanylate cyclase 2C | 0.00544439 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.00543687 |
| TBC1D4 | TBC1 domain family, member 4 | 0.00543001 |
| NDNF | neuron-derived neurotrophic factor | 0.00542868 |
| CEL | carboxyl ester lipase | 0.00542566 |
| CALCRL | calcitonin receptor-like | 0.00542301 |
| CCNE2 | cyclin E2 | 0.00541088 |
| PTGES | prostaglandin E synthase | 0.00540788 |
| PLXNC1 | plexin C1 | 0.00540296 |
| NID2 | nidogen 2 (osteonidogen) | 0.00540077 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00537593 |
| TLR2 | toll-like receptor 2 | 0.00537354 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 | 0.00533842 |
| TSPAN4 | tetraspanin 4 | 0.00532791 |
| NSL1 | NSL1, MIS12 kinetochore complex component | 0.00532009 |
| FOXA1 | forkhead box A1 | 0.0053168 |
| VANGL1 | VANGL planar cell polarity protein 1 | 0.00531557 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00531029 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | 0.00529696 |
| MORC4 | MORC family CW-type zinc finger 4 | 0.00529027 |
| ICAM2 | intercellular adhesion molecule 2 | 0.00527071 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00526879 |
| ADRA2A | adrenoceptor alpha 2A | 0.00526542 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00526123 |
| PSPH | phosphoserine phosphatase | 0.00525576 |
| B3GNT1 | 0.00525472 | |
| SOAT1 | sterol O-acyltransferase 1 | 0.00523416 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00522116 |
| ZNF267 | zinc finger protein 267 | 0.00521881 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 | 0.00521373 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00521356 |
| DMBT1 | deleted in malignant brain tumors 1 | 0.00521252 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.00521062 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 0.00520904 |
| DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 | 0.00519578 |
| HTRA1 | HtrA serine peptidase 1 | 0.00517489 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.00517406 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00517373 |
| NANS | N-acetylneuraminic acid synthase | 0.0051726 |
| CLGN | calmegin | 0.00516424 |
| LDLRAP1 | low density lipoprotein receptor adaptor protein 1 | 0.00516232 |
| ZNF189 | zinc finger protein 189 | 0.00516143 |
| UPK1B | uroplakin 1B | 0.00515549 |
| THBD | thrombomodulin | 0.00515136 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00515037 |
| CALML5 | calmodulin-like 5 | 0.0051478 |
| GPC1 | glypican 1 | 0.00513234 |
| RNFT2 | ring finger protein, transmembrane 2 | 0.00512809 |
| CBR3 | carbonyl reductase 3 | 0.00511927 |
| LHFP | lipoma HMGIC fusion partner | 0.00511919 |
| GSTO1 | glutathione S-transferase omega 1 | 0.00511724 |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 | 0.00511634 |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 | 0.00511311 |
| EVL | Enah/Vasp-like | 0.00511036 |
| COMP | cartilage oligomeric matrix protein | 0.00510492 |
| SLC38A6 | solute carrier family 38, member 6 | 0.00509066 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.00508267 |
| SIRT5 | sirtuin 5 | 0.0050807 |
| AFF1 | AF4/FMR2 family, member 1 | 0.00507995 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00507726 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CHP1 | calcineurin-like EF-hand protein 1 | -0.0151649 |
| GNAS | GNAS complex locus | -0.0150638 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0125782 |
| MGLL | monoglyceride lipase | -0.0121939 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.0116779 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.0114163 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0112402 |
| ATF3 | activating transcription factor 3 | -0.0110592 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0110331 |
| KRT14 | keratin 14, type I | -0.0106973 |
| SIRT3 | sirtuin 3 | -0.0104671 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0100294 |
| ZNF589 | zinc finger protein 589 | -0.0100047 |
| ASS1 | argininosuccinate synthase 1 | -0.00996368 |
| CDA | cytidine deaminase | -0.00996026 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.00970732 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.00970333 |
| TUBA4A | tubulin, alpha 4a | -0.00968867 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0096121 |
| NEFM | neurofilament, medium polypeptide | -0.00935111 |
| KLF6 | Kruppel-like factor 6 | -0.00935019 |
| BST2 | bone marrow stromal cell antigen 2 | -0.00931848 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00924416 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | -0.00910044 |
| PTN | pleiotrophin | -0.00902228 |
| ZIC1 | Zic family member 1 | -0.00883749 |
| BEX1 | brain expressed, X-linked 1 | -0.00877014 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00866299 |
| FGG | fibrinogen gamma chain | -0.0086568 |
| EGR2 | early growth response 2 | -0.00854054 |
| ALB | albumin | -0.00850979 |
| MX1 | MX dynamin-like GTPase 1 | -0.0084515 |
| APOB | apolipoprotein B | -0.00842553 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | -0.00828428 |
| BRD4 | bromodomain containing 4 | -0.00826093 |
| TOX | thymocyte selection-associated high mobility group box | -0.00822879 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00821986 |
| NDRG1 | N-myc downstream regulated 1 | -0.00821838 |
| PDZD2 | PDZ domain containing 2 | -0.00809038 |
| NES | nestin | -0.00806594 |
| SPRR3 | small proline-rich protein 3 | -0.00798786 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.0078925 |
| PCP4 | Purkinje cell protein 4 | -0.00785594 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00774067 |
| KLK10 | kallikrein-related peptidase 10 | -0.00773904 |
| APOA1 | apolipoprotein A-I | -0.00770811 |
| A2M | alpha-2-macroglobulin | -0.00768969 |
| PGBD5 | piggyBac transposable element derived 5 | -0.00768618 |
| H1-0 | H1.0 linker histone | -0.00762326 |
| AOC1 | amine oxidase, copper containing 1 | -0.00759102 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00752217 |
| PEG10 | paternally expressed 10 | -0.00752212 |
| FGF9 | fibroblast growth factor 9 | -0.00750166 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.00746117 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00743395 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00743264 |
| IFRD1 | interferon-related developmental regulator 1 | -0.00739597 |
| PAM | peptidylglycine alpha-amidating monooxygenase | -0.0073566 |
| JUNB | jun B proto-oncogene | -0.00735478 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00727437 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00727377 |
| AREG | amphiregulin | -0.00724715 |
| SPRR1B | small proline-rich protein 1B | -0.00721354 |
| SPON2 | spondin 2, extracellular matrix protein | -0.00719538 |
| SFN | stratifin | -0.00718018 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00712651 |
| MMP2 | matrix metallopeptidase 2 | -0.00712442 |
| KRT23 | keratin 23, type I | -0.00711093 |
| KLK11 | kallikrein-related peptidase 11 | -0.00710294 |
| MCM2 | minichromosome maintenance complex component 2 | -0.00709985 |
| ECM1 | extracellular matrix protein 1 | -0.00709378 |
| CNTN1 | contactin 1 | -0.00708262 |
| FGA | fibrinogen alpha chain | -0.0070418 |
| RGCC | regulator of cell cycle | -0.00700078 |
| EGR1 | early growth response 1 | -0.00699048 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.00697188 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.00695819 |
| EPS8L2 | EPS8-like 2 | -0.00694975 |
| CDO1 | cysteine dioxygenase type 1 | -0.00694012 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00689982 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.00688866 |
| CTSZ | cathepsin Z | -0.00684216 |
| RTN2 | reticulon 2 | -0.00683686 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00683025 |
| HOXB2 | homeobox B2 | -0.00681876 |
| PKP1 | plakophilin 1 | -0.00678964 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.00677504 |
| KLK5 | kallikrein-related peptidase 5 | -0.00676809 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00675073 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.00674548 |
| IGF2R | insulin-like growth factor 2 receptor | -0.00670005 |
| JMJD6 | jumonji domain containing 6 | -0.00666945 |
| GPC3 | glypican 3 | -0.00661231 |
| PCNA | proliferating cell nuclear antigen | -0.00661011 |
| FGB | fibrinogen beta chain | -0.00656996 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00655863 |
| PXDN | peroxidasin | -0.00654892 |
| NRCAM | neuronal cell adhesion molecule | -0.00652044 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00650913 |
| CD81 | CD81 molecule | -0.00650125 |
| TMPRSS11E | transmembrane protease, serine 11E | -0.00648943 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -0.00648132 |
| REC8 | REC8 meiotic recombination protein | -0.00645058 |
| TECR | trans-2,3-enoyl-CoA reductase | -0.00642411 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -0.00639712 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00636678 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00635912 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00635144 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00634697 |
| SETBP1 | SET binding protein 1 | -0.00633226 |
| GSN | gelsolin | -0.00632915 |
| G0S2 | G0/G1 switch 2 | -0.00630151 |
| NCOA2 | nuclear receptor coactivator 2 | -0.00628462 |
| EMP1 | epithelial membrane protein 1 | -0.00625566 |
| KIF5B | kinesin family member 5B | -0.00625273 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.00624838 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | -0.0062414 |
| TUBB3 | tubulin, beta 3 class III | -0.00623104 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | -0.00621412 |
| DSG3 | desmoglein 3 | -0.00621201 |
| TMEM176A | transmembrane protein 176A | -0.00621133 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00619517 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00616953 |
| SOX10 | SRY (sex determining region Y)-box 10 | -0.0061606 |
| MINK1 | misshapen-like kinase 1 | -0.00614772 |
| TRIB3 | tribbles pseudokinase 3 | -0.00614284 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00614167 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00613712 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00612677 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00612307 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00610843 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00610462 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00609142 |
| ATF4 | activating transcription factor 4 | -0.00608663 |
| ORM1 | orosomucoid 1 | -0.00607303 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.00603646 |
| CTSG | cathepsin G | -0.00603475 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00600478 |
| USP47 | ubiquitin specific peptidase 47 | -0.00597887 |
| CAPRIN2 | caprin family member 2 | -0.00594554 |
| MT1X | metallothionein 1X | -0.00591737 |
| GSE1 | Gse1 coiled-coil protein | -0.0059126 |
| BMP2 | bone morphogenetic protein 2 | -0.00590111 |
| KRT6A | keratin 6A, type II | -0.00589238 |
| TPBG | trophoblast glycoprotein | -0.0058911 |
| KRT5 | keratin 5, type II | -0.0058786 |
| SPRR1A | small proline-rich protein 1A | -0.00586391 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.00586035 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | -0.00583576 |
| CBS | cystathionine-beta-synthase | -0.00583294 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | -0.00581826 |
| CHGB | chromogranin B | -0.00579958 |
| CLTB | clathrin, light chain B | -0.00579764 |
| NIT1 | nitrilase 1 | -0.00579335 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00577538 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.00576936 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.00576511 |
| DCHS1 | dachsous cadherin-related 1 | -0.00575045 |
| BRD2 | bromodomain containing 2 | -0.00574012 |
| LMNA | lamin A/C | -0.00573481 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | -0.00573275 |
| VSNL1 | visinin-like 1 | -0.00573109 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.0056997 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.00569438 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00568593 |
| RBM34 | RNA binding motif protein 34 | -0.00568134 |
| GOLGA8A | golgin A8 family, member A | -0.00567983 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.00565563 |
| CA11 | carbonic anhydrase XI | -0.00564134 |
| MFSD10 | major facilitator superfamily domain containing 10 | -0.00562962 |
| HBEGF | heparin-binding EGF-like growth factor | -0.00562918 |
| EPS8L1 | EPS8-like 1 | -0.00562423 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00561852 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00559384 |
| WBP11 | WW domain binding protein 11 | -0.00556485 |
| TSPO | translocator protein (18kDa) | -0.00555626 |
| STMN2 | stathmin 2 | -0.00553652 |
| ANGPTL4 | angiopoietin-like 4 | -0.00552586 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | -0.00551765 |
| SIK1 | salt-inducible kinase 1 | -0.00551575 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0055126 |
| SLC22A18 | solute carrier family 22, member 18 | -0.00551101 |
| MNT | MAX network transcriptional repressor | -0.00549655 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00549204 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | -0.00548518 |
| DSP | desmoplakin | -0.00548435 |
| NARS1 | asparaginyl-tRNA synthetase 1 | -0.0054721 |
| APOA2 | apolipoprotein A-II | -0.0054648 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.00546455 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.00545897 |
| STC2 | stanniocalcin 2 | -0.00545016 |
| SYT11 | synaptotagmin XI | -0.00544585 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00544313 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | -0.00544221 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00543991 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00543946 |
| AMOTL2 | angiomotin like 2 | -0.00542721 |
| NPTX1 | neuronal pentraxin I | -0.00542549 |
| TMEM176B | transmembrane protein 176B | -0.00542256 |
| ARGLU1 | arginine and glutamate rich 1 | -0.00542171 |
| EGR3 | early growth response 3 | -0.00541342 |
| GTPBP2 | GTP binding protein 2 | -0.00539426 |
| MCL1 | myeloid cell leukemia 1 | -0.00539371 |
| REXO2 | RNA exonuclease 2 | -0.00538695 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | -0.00538584 |
| HMOX1 | heme oxygenase 1 | -0.00538545 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | -0.00538339 |
| ACAA2 | acetyl-CoA acyltransferase 2 | -0.00537798 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | -0.00537787 |
| MIR22HG | MIR22 host gene | -0.00536991 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.00536143 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00534409 |
| YME1L1 | YME1-like 1 ATPase | -0.00534262 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.00533944 |
| ANXA11 | annexin A11 | -0.00533941 |
| ZNF395 | zinc finger protein 395 | -0.00529743 |
| CTSD | cathepsin D | -0.00529558 |
| KRT6B | keratin 6B, type II | -0.0052906 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00528799 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | -0.00527712 |
| KIF13B | kinesin family member 13B | -0.00525281 |
| SMAD7 | SMAD family member 7 | -0.00523744 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.00523296 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00523131 |
| CAPN6 | calpain 6 | -0.00523041 |
| HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | -0.0052292 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.00522605 |
| PMM2 | phosphomannomutase 2 | -0.00522327 |
| CES1 | carboxylesterase 1 | -0.00521803 |
| ABCC10 | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 | -0.00521635 |
| TTR | transthyretin | -0.00521552 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00520216 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0052005 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.00516968 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -0.00516754 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.00515942 |
| ARG2 | arginase 2 | -0.00514873 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00514581 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.00514252 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.0051394 |
| PEG3 | paternally expressed 3 | -0.00513422 |
| CTSB | cathepsin B | -0.00510823 |
| PCGF3 | polycomb group ring finger 3 | -0.00510176 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00509944 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -0.00508787 |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 | -0.00508346 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.00507203 |
| ACTN4 | actinin, alpha 4 | -0.00507035 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | -0.00506473 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00505927 |
