RAC3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)|The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5881)
External Link http://www.ncbi.nlm.nih.gov/gene/5881
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Genes

301 interacting proteins for RAC3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABR active BCR-related
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
AKAP13 A kinase (PRKA) anchor protein 13
ALYREF Aly/REF export factor
ANAPC10 anaphase promoting complex subunit 10
ANKRD11 ankyrin repeat domain 11
ANXA2 annexin A2
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AR androgen receptor
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARCN1 archain 1
ARHGAP1 Rho GTPase activating protein 1
ARHGAP11A Rho GTPase activating protein 11A
ARHGAP11B Rho GTPase activating protein 11B
ARHGAP12 Rho GTPase activating protein 12
ARHGAP15 Rho GTPase activating protein 15
ARHGAP17 Rho GTPase activating protein 17
ARHGAP18 Rho GTPase activating protein 18
ARHGAP19 Rho GTPase activating protein 19
ARHGAP20 Rho GTPase activating protein 20
ARHGAP22 Rho GTPase activating protein 22
ARHGAP23 Rho GTPase activating protein 23
ARHGAP24 Rho GTPase activating protein 24
ARHGAP25 Rho GTPase activating protein 25
ARHGAP26 Rho GTPase activating protein 26
ARHGAP28 Rho GTPase activating protein 28
ARHGAP29 Rho GTPase activating protein 29
ARHGAP30 Rho GTPase activating protein 30
ARHGAP31 Rho GTPase activating protein 31
ARHGAP33 Rho GTPase activating protein 33
ARHGAP35 Rho GTPase activating protein 35
ARHGAP36 Rho GTPase activating protein 36
ARHGAP39 Rho GTPase activating protein 39
ARHGAP4 Rho GTPase activating protein 4
ARHGAP40 Rho GTPase activating protein 40
ARHGAP44 Rho GTPase activating protein 44
ARHGAP5 Rho GTPase activating protein 5
ARHGAP6 Rho GTPase activating protein 6
ARHGAP8 Rho GTPase activating protein 8
ARHGAP9 Rho GTPase activating protein 9
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ARL1 ADP-ribosylation factor-like 1
ARL8B ADP-ribosylation factor-like 8B
ASF1A anti-silencing function 1A histone chaperone
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BCAS2 breast carcinoma amplified sequence 2
BCL7C B-cell CLL/lymphoma 7C
BCR breakpoint cluster region
BET1 Bet1 golgi vesicular membrane trafficking protein
C11ORF73 chromosome 11 open reading frame 73
C1ORF35 chromosome 1 open reading frame 35
CACYBP calcyclin binding protein
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAMSAP3 calmodulin regulated spectrin-associated protein family, member 3
CCDC59 coiled-coil domain containing 59
CDC23 cell division cycle 23
CDC42 cell division cycle 42
CDK2 cyclin-dependent kinase 2
CELF2 CUGBP, Elav-like family member 2
CEP55 centrosomal protein 55kDa
CFL1 cofilin 1 (non-muscle)
CHAF1A chromatin assembly factor 1, subunit A (p150)
CHN1 chimerin 1
CHN2 chimerin 2
CIB1 calcium and integrin binding 1 (calmyrin)
CLASP1 cytoplasmic linker associated protein 1
CNOT12 CCR4-NOT transcription complex subunit 12
COA5 cytochrome c oxidase assembly factor 5
COL1A1 collagen, type I, alpha 1
COX5B cytochrome c oxidase subunit Vb
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CREBBP CREB binding protein
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTPS1 CTP synthase 1
CUL2 cullin 2
CWC15 CWC15 spliceosome-associated protein
DAZAP1 DAZ associated protein 1
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DEPDC1B DEP domain containing 1B
DEPDC7 DEP domain containing 7
DES desmin
DGCR14 DiGeorge syndrome critical region gene 14
DLC1 DLC1 Rho GTPase activating protein
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DYNLL2 dynein, light chain, LC8-type 2
ECT2 epithelial cell transforming 2
ESR1 estrogen receptor 1
FAM13A family with sequence similarity 13, member A
FAM13B family with sequence similarity 13, member B
FBXL19 F-box and leucine-rich repeat protein 19
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD2 FYVE, RhoGEF and PH domain containing 2
FGD3 FYVE, RhoGEF and PH domain containing 3
FGD4 FYVE, RhoGEF and PH domain containing 4
FIP1L1 factor interacting with PAPOLA and CPSF1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FLYWCH1 FLYWCH-type zinc finger 1
GATAD2A GATA zinc finger domain containing 2A
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GFAP glial fibrillary acidic protein
GIPC1 GIPC PDZ domain containing family, member 1
GMIP GEM interacting protein
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GSTP1 glutathione S-transferase pi 1
GTSE1 G-2 and S-phase expressed 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIST1H1D histone cluster 1, H1d
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HMGB1 high mobility group box 1
HMHA1 histocompatibility (minor) HA-1
HMMR hyaluronan-mediated motility receptor (RHAMM)
HNF1A HNF1 homeobox A
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HOXA9 homeobox A9
HOXB9 homeobox B9
HOXC8 homeobox C8
HOXC9 homeobox C9
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IER3IP1 immediate early response 3 interacting protein 1
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IPO5 importin 5
ITSN1 intersectin 1 (SH3 domain protein)
KALRN kalirin, RhoGEF kinase
KLF16 Kruppel-like factor 16
LDHB lactate dehydrogenase B
LENG1 leukocyte receptor cluster (LRC) member 1
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP7D2 MAP7 domain containing 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MARK2 MAP/microtubule affinity-regulating kinase 2
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MCF2 MCF.2 cell line derived transforming sequence
MCF2L MCF.2 cell line derived transforming sequence-like
MED30 mediator complex subunit 30
MED8 mediator complex subunit 8
MKI67 marker of proliferation Ki-67
MSANTD4 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
MSX1 msh homeobox 1
MYH10 myosin, heavy chain 10, non-muscle
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYO9B myosin IXB
MZT2B mitotic spindle organizing protein 2B
NACA nascent polypeptide-associated complex alpha subunit
NAP1L1 nucleosome assembly protein 1-like 1
NCOR1 nuclear receptor corepressor 1
NEFM neurofilament, medium polypeptide
NET1 neuroepithelial cell transforming 1
NGEF neuronal guanine nucleotide exchange factor
NRBP1 nuclear receptor binding protein 1
NUCLEOLIN nucleolin multifunctional protein
NUP155 nucleoporin 155kDa
NUP50 nucleoporin 50kDa
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OCRL oculocerebrorenal syndrome of Lowe
OPHN1 oligophrenin 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDCD6 programmed cell death 6
PDCD7 programmed cell death 7
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLS3 plastin 3
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1
PRC1 protein regulator of cytokinesis 1
PRMT1 protein arginine methyltransferase 1
PRPF19 pre-mRNA processing factor 19
PRPF31 pre-mRNA processing factor 31
PTBP3 polypyrimidine tract binding protein 3
RAB10 RAB10, member RAS oncogene family
RAB1A RAB1A, member RAS oncogene family
RAB23 RAB23, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RABAC1 Rab acceptor 1 (prenylated)
RACGAP1 Rac GTPase activating protein 1
RAE1 ribonucleic acid export 1
RALBP1 ralA binding protein 1
RAN RAN, member RAS oncogene family
RARA retinoic acid receptor, alpha
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBM39 RNA binding motif protein 39
RBM41 RNA binding motif protein 41
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RER1 retention in endoplasmic reticulum sorting receptor 1
RHOA ras homolog family member A
RHOB ras homolog family member B
RHOC ras homolog family member C
RNPC3 RNA-binding region (RNP1, RRM) containing 3
RPL11 ribosomal protein L11
RPL30 ribosomal protein L30
RPL35A ribosomal protein L35a
RPL38 ribosomal protein L38
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
RPS10 ribosomal protein S10
RPS11 ribosomal protein S11
RPS14 ribosomal protein S14
RPS19BP1 ribosomal protein S19 binding protein 1
RPS27 ribosomal protein S27
RPS28 ribosomal protein S28
RPS4X ribosomal protein S4, X-linked
RPS7 ribosomal protein S7
RSRC1 arginine/serine-rich coiled-coil 1
RWDD1 RWD domain containing 1
RXRA retinoid X receptor, alpha
SACK1D scaffolding CK1 anchoring protein D
SEC16A SEC16 homolog A (S. cerevisiae)
SEC24B SEC24 family member B
SEPT9 septin 9
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SF3B5 splicing factor 3b, subunit 5, 10kDa
SKA3 spindle and kinetochore associated complex subunit 3
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SNAP29 synaptosomal-associated protein, 29kDa
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SNRPA small nuclear ribonucleoprotein polypeptide A
SNRPE small nuclear ribonucleoprotein polypeptide E
SNX3 sorting nexin 3
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SRI sorcin
SRP19 signal recognition particle 19kDa
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SSRP1 structure specific recognition protein 1
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD8 StAR-related lipid transfer (START) domain containing 8
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAGAP T-cell activation RhoGTPase activating protein
TARDBP TAR DNA binding protein
TERF2 telomeric repeat binding factor 2
TF transferrin
TFCP2 transcription factor CP2
THOC2 THO complex 2
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TIAM1 T-cell lymphoma invasion and metastasis 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast)
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMPO thymopoietin
TNPO1 transportin 1
TNPO2 transportin 2
TNRC6C trinucleotide repeat containing 6C
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TRIM33 tripartite motif containing 33
TRIO trio Rho guanine nucleotide exchange factor
TRIP10 thyroid hormone receptor interactor 10
TRIP11 thyroid hormone receptor interactor 11
TUBA1A tubulin, alpha 1a
TUBA1C tubulin, alpha 1c
TUBB tubulin, beta class I
TXN thioredoxin
UBC ubiquitin C
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
VAT1 vesicle amine transport 1
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
WAS Wiskott-Aldrich syndrome
WDR41 WD repeat domain 41
WDR48 WD repeat domain 48
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPO1 exportin 1
XPO5 exportin 5
YIPF1 Yip1 domain family, member 1
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZMAT5 zinc finger, matrin-type 5
ZNF706 zinc finger protein 706
ZNF768 zinc finger protein 768