RAD1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description RAD1 checkpoint DNA exonuclease|This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009] (NCBI Entrez Gene Database, 5810)
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Genes

355 genes differentially expressed following the RAD1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TMIGD3 transmembrane and immunoglobulin domain containing 3 2.6842
KRTAP13-4 keratin associated protein 13-4 2.6842
CAPN9 calpain 9 2.6842
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 2.6842
KLK5 kallikrein-related peptidase 5 2.6842
IL33 interleukin 33 2.6842
FIBIN fin bud initiation factor homolog (zebrafish) 2.6842
TRAF3IP3 TRAF3 interacting protein 3 2.6842
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 2.6842
ADAM8 ADAM metallopeptidase domain 8 2.6842
CTF1 cardiotrophin 1 2.6842
ARGFX arginine-fifty homeobox 2.6842
SLC26A7 solute carrier family 26 (anion exchanger), member 7 2.6842
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 2.6842
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 2.6842
IER5L immediate early response 5-like 2.6842
SQOR sulfide quinone oxidoreductase 2.6842
H2BC3 H2B clustered histone 3 2.6842
CFB complement factor B 2.6842
LYPD5 LY6/PLAUR domain containing 5 2.6842
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1 2.6842
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 2.6842
C19ORF38 chromosome 19 open reading frame 38 2.6842
TNS4 tensin 4 2.6842
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 2.6842
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 2.66106
DLX4 distal-less homeobox 4 2.64315
SLC26A4 solute carrier family 26 (anion exchanger), member 4 2.64315
OCSTAMP osteoclast stimulatory transmembrane protein 2.64315
BSND barttin CLCNK-type chloride channel accessory beta subunit 2.64315
SIX1 SIX homeobox 1 2.64315
TREM2 triggering receptor expressed on myeloid cells 2 2.64315
ZRANB2 zinc finger, RAN-binding domain containing 2 2.64315
PRB1 proline-rich protein BstNI subfamily 1 2.64315
USH1G Usher syndrome 1G (autosomal recessive) 2.64315
KLHL35 kelch-like family member 35 2.64315
SIX3 SIX homeobox 3 2.64315
FOLR1 folate receptor 1 (adult) 2.64315
CD5 CD5 molecule 2.64315
CEMP1 cementum protein 1 2.64315
OR51L1 olfactory receptor, family 51, subfamily L, member 1 2.64315
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 2.64315
FETUB fetuin B 2.64315
ASB17 ankyrin repeat and SOCS box containing 17 2.64315
AKIP1 A kinase (PRKA) interacting protein 1 2.64315
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 2.64315
GRIA2 glutamate receptor, ionotropic, AMPA 2 2.64315
DRGX dorsal root ganglia homeobox 2.64315
ASPA aspartoacylase 2.64315
ALPK2 alpha-kinase 2 2.64315
PAX7 paired box 7 2.64315
SOX18 SRY (sex determining region Y)-box 18 2.64315
CD160 CD160 molecule 2.64315
PGAM2 phosphoglycerate mutase 2 (muscle) 2.64315
MUC6 mucin 6, oligomeric mucus/gel-forming 2.64315
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 2.64315
ANKRD34A ankyrin repeat domain 34A 2.64315
OR1A1 olfactory receptor, family 1, subfamily A, member 1 2.64315
HES3 hes family bHLH transcription factor 3 2.64315
SSTR1 somatostatin receptor 1 2.64315
MID1 midline 1 2.64315
LOC122455340 uncharacterized LOC122455340 2.64315
CCDC9B coiled-coil domain containing 9B 2.64315
H2BC1 H2B clustered histone 1 2.64315
EIF2S3B eukaryotic translation initiation factor 2 subunit gamma B 2.64315
GPR33 G protein-coupled receptor 33 (gene/pseudogene) 2.64315
FMO3 flavin containing monooxygenase 3 2.64315
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 2.64315
IQCF3 IQ motif containing F3 2.64315
WNT16 wingless-type MMTV integration site family, member 16 2.64315
RAB36 RAB36, member RAS oncogene family 2.64315
FCMR Fc fragment of IgM receptor 2.64315
EPOP elongin BC and polycomb repressive complex 2 associated protein 2.64315
CCN5 cellular communication network factor 5 2.64315
SMIM39 small integral membrane protein 39 2.64315
SPATA31G1 SPATA31 subfamily G member 1 2.64315
CIMIP3 ciliary microtubule inner protein 3 2.64315
CIMAP1D CIMAP1 family member D 2.64315
LOC124903372 uncharacterized LOC124903372 2.64315
INSYN1 inhibitory synaptic factor 1 2.64315
H4C14 H4 clustered histone 14 2.64315
MYMK myomaker, myoblast fusion factor 2.64315
ARMH2 armadillo like helical domain containing 2 2.64315
PCARE photoreceptor cilium actin regulator 2.64315
TSPAN1 tetraspanin 1 2.64315
KHDC1L KH homology domain containing 1-like 2.64315
TLR8 toll-like receptor 8 2.64315
ZIC4 Zic family member 4 2.64315
NR1I3 nuclear receptor subfamily 1, group I, member 3 2.64315
IDO2 indoleamine 2,3-dioxygenase 2 2.64315
LRRC3C leucine rich repeat containing 3C 2.64315
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 2.64315
PCDHA3 protocadherin alpha 3 2.64315
PCDHA2 protocadherin alpha 2 2.64315
FOXD1 forkhead box D1 2.64315
OR2A7 olfactory receptor, family 2, subfamily A, member 7 2.64315
GDF10 growth differentiation factor 10 2.64315
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 2.64315
C11ORF21 chromosome 11 open reading frame 21 2.64315
GATA1 GATA binding protein 1 (globin transcription factor 1) 2.64315
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 2.64315
COX8C cytochrome c oxidase subunit VIIIC 2.64315
LRRC72 leucine rich repeat containing 72 2.64315
OOSP1 oocyte secreted protein 1, pseudogene 2.64315
GSC goosecoid homeobox 2.64315
CCR8 chemokine (C-C motif) receptor 8 2.64315
EXOC3L1 exocyst complex component 3-like 1 2.64315
TBX5 T-box 5 2.64315
ELAVL2 ELAV like neuron-specific RNA binding protein 2 2.64315
POTEI POTE ankyrin domain family, member I 2.64315
BTNL8 butyrophilin-like 8 2.64315
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 2.64315
ANKRD63 ankyrin repeat domain 63 2.64315
TMEM61 transmembrane protein 61 2.64315
WFDC6 WAP four-disulfide core domain 6 2.64315
TDRD10 tudor domain containing 10 2.64315
C10ORF71 chromosome 10 open reading frame 71 2.64315
NPFFR1 neuropeptide FF receptor 1 2.64315
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 2.64315
THTPA thiamine triphosphatase 2.64315
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 2.64315
PRRX1 paired related homeobox 1 2.64315
FAM25G family with sequence similarity 25, member G 2.64315
LPAR5 lysophosphatidic acid receptor 5 2.64315
TMIGD2 transmembrane and immunoglobulin domain containing 2 2.64315
PRSS55 protease, serine, 55 2.64315
ACOX2 acyl-CoA oxidase 2, branched chain 2.64315
FNDC9 fibronectin type III domain containing 9 2.64315
MRGPRE MAS-related GPR, member E 2.64315
EBLN1 endogenous Bornavirus-like nucleoprotein 1 2.64315
MAB21L3 mab-21-like 3 (C. elegans) 2.64315
PCDHGA2 protocadherin gamma subfamily A, 2 2.64315
BAHCC1 BAH domain and coiled-coil containing 1 2.64315
C11ORF42 chromosome 11 open reading frame 42 2.64315
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.64315
PLA2G5 phospholipase A2, group V 2.64315
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 2.64315
VMO1 vitelline membrane outer layer 1 homolog (chicken) 2.64315
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 2.64315
LRRC24 leucine rich repeat containing 24 2.64315
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.64315
CRTAM cytotoxic and regulatory T cell molecule 2.64315
CCNI2 cyclin I family, member 2 2.64315
CTSF cathepsin F 2.64315
VWA3B von Willebrand factor A domain containing 3B 2.64315
DSC1 desmocollin 1 2.64315
DHH desert hedgehog 2.64315
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 2.64315
COL6A5 collagen, type VI, alpha 5 2.64315
TH tyrosine hydroxylase 2.64315
CLEC9A C-type lectin domain family 9, member A 2.64315
IP6K3 inositol hexakisphosphate kinase 3 2.64315
PRH2 proline-rich protein HaeIII subfamily 2 2.64315
NBPF8 neuroblastoma breakpoint family, member 8 2.64315
HEPHL1 hephaestin-like 1 2.64315
CD3E CD3e molecule, epsilon (CD3-TCR complex) 2.64315
RAB7B RAB7B, member RAS oncogene family 2.64315
OXER1 oxoeicosanoid (OXE) receptor 1 2.64315
IL17B interleukin 17B 2.64315
NLRP5 NLR family, pyrin domain containing 5 2.64315
NLRP9 NLR family, pyrin domain containing 9 2.64315
IRX5 iroquois homeobox 5 2.64315
PITX1 paired-like homeodomain 1 2.64315
TMEM184A transmembrane protein 184A 2.64315
DHRS9 dehydrogenase/reductase (SDR family) member 9 2.64315
IL37 interleukin 37 2.64315
PRSS22 protease, serine, 22 2.64315
KIAA1755 KIAA1755 2.64315
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 2.64315
SPAG9 sperm associated antigen 9 2.64315
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6 2.64315
MYO1G myosin IG 2.64315
AHSG alpha-2-HS-glycoprotein 2.64315
RCC1 regulator of chromosome condensation 1 2.64315
RPEL1 ribulose-5-phosphate-3-epimerase-like 1 2.64315
ISX intestine-specific homeobox 2.64315
GPBAR1 G protein-coupled bile acid receptor 1 2.64315
EPN3 epsin 3 2.64315
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 2.64315
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 2.60545
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 2.58959
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 2.58959
CLCNKB chloride channel, voltage-sensitive Kb 2.58959
CCNB1 cyclin B1 2.58635
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase 2.57223
HPS4 Hermansky-Pudlak syndrome 4 2.53135
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) 2.52814
KLRG1 killer cell lectin-like receptor subfamily G, member 1 2.52814
CEP295NL CEP295 N-terminal like 2.51348
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 2.51328
ATE1 arginyltransferase 1 2.50892
PAIP2B poly(A) binding protein interacting protein 2B 2.50124
ZBTB7A zinc finger and BTB domain containing 7A 2.43157
YBEY ybeY metallopeptidase (putative) 2.42902
DMP1 dentin matrix acidic phosphoprotein 1 2.42529
SHISA3 shisa family member 3 2.42529
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 2.41925
IKBIP IKBKB interacting protein 2.41796
DUSP13B dual specificity phosphatase 13B 2.41589
VPS26B vacuolar protein sorting 26 homolog B (S. pombe) 2.41494
CERS1 ceramide synthase 1 2.41494
GRIP2 glutamate receptor interacting protein 2 2.38566
HINT3 histidine triad nucleotide binding protein 3 2.37263
MMD monocyte to macrophage differentiation-associated 2.35289
DNAAF10 dynein axonemal assembly factor 10 2.34794
GLRX3 glutaredoxin 3 2.34794
ITGA10 integrin, alpha 10 2.3374
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 2.32527
TMEM131 transmembrane protein 131 2.29743
ZNF284 zinc finger protein 284 2.28339
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 2.26419
PCDHB15 protocadherin beta 15 2.24824
FLCN folliculin 2.24737
EDNRA endothelin receptor type A 2.24241
LATS1 large tumor suppressor kinase 1 2.2177
RUFY2 RUN and FYVE domain containing 2 2.2177
GATAD2A GATA zinc finger domain containing 2A 2.21766
AP1AR adaptor-related protein complex 1 associated regulatory protein 2.21766
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 2.19487
PLCL2 phospholipase C-like 2 2.18854
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4 2.15999
DMXL2 Dmx-like 2 2.13037
ORC3 origin recognition complex, subunit 3 2.09445
CLCN3 chloride channel, voltage-sensitive 3 2.08516
AKNA AT-hook transcription factor 2.07388
NEIL1 nei endonuclease VIII-like 1 (E. coli) 2.06445
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 2.05797
MED25 mediator complex subunit 25 2.04201
MIDN midnolin 2.04162
NEB nebulin 2.03938
BMPR1B bone morphogenetic protein receptor, type IB 2.03938
ANKRD13C ankyrin repeat domain 13C 2.03138
LCAT lecithin-cholesterol acyltransferase 2.01437

decreased expression

Symbol Name Standardized Value
RAB40A RAB40A, member RAS oncogene family -2.6842
ARF6 ADP-ribosylation factor 6 -2.67479
FBL fibrillarin -2.64315
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 -2.64315
SCUBE2 signal peptide, CUB domain, EGF-like 2 -2.64315
SNX32 sorting nexin 32 -2.64315
CRYBA1 crystallin, beta A1 -2.64315
CAMLG calcium modulating ligand -2.64315
PTH2R parathyroid hormone 2 receptor -2.64315
DAPK2 death-associated protein kinase 2 -2.64315
SHOC2 soc-2 suppressor of clear homolog (C. elegans) -2.64315
RUMY1 regulator of UNG2 and MKLN1 interacting yippee protein 1 -2.64315
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 -2.64315
FXN frataxin -2.64315
TMT1B thiol methyltransferase 1B -2.64315
FCRLB Fc receptor-like B -2.64315
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 -2.64315
LRRC4C leucine rich repeat containing 4C -2.64315
PLAC8L1 PLAC8-like 1 -2.64315
KYNU kynureninase -2.64315
C17ORF49 chromosome 17 open reading frame 49 -2.64315
FAS Fas cell surface death receptor -2.64315
RB1CC1 RB1-inducible coiled-coil 1 -2.62983
METTL24 methyltransferase like 24 -2.58959
AMER2 APC membrane recruitment protein 2 -2.58959
SHE Src homology 2 domain containing E -2.58959
TWIST1 twist family bHLH transcription factor 1 -2.58959
ZNF804B zinc finger protein 804B -2.58959
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 -2.58959
GRAP2 GRB2-related adaptor protein 2 -2.58959
SPINT4 serine peptidase inhibitor, Kunitz type 4 -2.58959
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) -2.58959
DES desmin -2.58959
SLCO1B1 solute carrier organic anion transporter family, member 1B1 -2.58959
IHO1 interactor of HORMAD1 1 -2.58959
MARCHF1 membrane associated ring-CH-type finger 1 -2.58959
SCNN1D sodium channel, non voltage gated 1 delta subunit -2.58959
TAS1R1 taste receptor, type 1, member 1 -2.58959
PRRT1 proline-rich transmembrane protein 1 -2.58959
CCDC92 coiled-coil domain containing 92 -2.58959
CBLN3 cerebellin 3 precursor -2.58959
CHRNG cholinergic receptor, nicotinic, gamma (muscle) -2.58959
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2 -2.58959
MYBPHL myosin binding protein H-like -2.58959
OR52A5 olfactory receptor, family 52, subfamily A, member 5 -2.58959
LRRC55 leucine rich repeat containing 55 -2.58959
SCNN1G sodium channel, non voltage gated 1 gamma subunit -2.58959
ZNF593OS ZNF593 opposite strand -2.58959
ERICH6B glutamate-rich 6B -2.58959
CD53 CD53 molecule -2.58959
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 -2.58959
ARG1 arginase 1 -2.58959
CLIC5 chloride intracellular channel 5 -2.58959
PLAC8 placenta-specific 8 -2.58959
TMEM169 transmembrane protein 169 -2.58959
SMIM17 small integral membrane protein 17 -2.58959
LMX1B LIM homeobox transcription factor 1, beta -2.58959
SH2D4B SH2 domain containing 4B -2.58959
NTN5 netrin 5 -2.58959
CLUH clustered mitochondria (cluA/CLU1) homolog -2.58959
ADAM12 ADAM metallopeptidase domain 12 -2.58959
DRC1 dynein regulatory complex subunit 1 -2.58959
P4HB prolyl 4-hydroxylase, beta polypeptide -2.57713
FSTL5 follistatin-like 5 -2.56781
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 -2.55895
SUMO4 small ubiquitin-like modifier 4 -2.5516
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 -2.54921
PHF20 PHD finger protein 20 -2.54434
FAM163B family with sequence similarity 163, member B -2.52883
TSLIG3C tRNA splicing ligase complex subunit 3C -2.52883
NEMP1 nuclear envelope integral membrane protein 1 -2.52814
DTWD2 DTW domain containing 2 -2.51315
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -2.50892
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -2.50319
PCDHA6 protocadherin alpha 6 -2.47922
GPR18 G protein-coupled receptor 18 -2.46531
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled -2.45418
PSKH1 protein serine kinase H1 -2.38865
NUP153 nucleoporin 153kDa -2.38713
PNPLA3 patatin-like phospholipase domain containing 3 -2.3742
MFGE8 milk fat globule-EGF factor 8 protein -2.36889
CCDC200 coiled-coil domain containing 200 -2.35289
PRR5 proline rich 5 (renal) -2.35223
SLC35F5 solute carrier family 35, member F5 -2.32864
PRDM4 PR domain containing 4 -2.32527
BST1 bone marrow stromal cell antigen 1 -2.25966
NUAK2 NUAK family, SNF1-like kinase, 2 -2.2458
INTS14 integrator complex subunit 14 -2.24425
UFD1 ubiquitin recognition factor in ER associated degradation 1 -2.24088
LHX6 LIM homeobox 6 -2.22682
PEDS1 plasmanylethanolamine desaturase 1 -2.2177
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) -2.18424
EXPH5 exophilin 5 -2.16898
EPN1 epsin 1 -2.16765
EFNA5 ephrin-A5 -2.16765
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 -2.15449
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L -2.1522
FBLN5 fibulin 5 -2.1522
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) -2.1522
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -2.1522
SF3B5 splicing factor 3b, subunit 5, 10kDa -2.14682
IGSF10 immunoglobulin superfamily, member 10 -2.12981
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 -2.11922
NAIF1 nuclear apoptosis inducing factor 1 -2.11565
GTPBP4 GTP binding protein 4 -2.09344
DMAC2L distal membrane arm assembly component 2 like -2.0913
ZMYM6 zinc finger, MYM-type 6 -2.07994
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) -2.05813
PRKACB protein kinase, cAMP-dependent, catalytic, beta -2.04999
DCDC1 doublecortin domain containing 1 -2.04999
EML3 echinoderm microtubule associated protein like 3 -2.04999
TROAP trophinin associated protein -2.04984
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 -2.04338
SLC16A11 solute carrier family 16, member 11 -2.04338
RUNDC3B RUN domain containing 3B -2.04338
ZSCAN22 zinc finger and SCAN domain containing 22 -2.04338
KCNK1 potassium channel, two pore domain subfamily K, member 1 -2.04162
RPP25L ribonuclease P/MRP 25kDa subunit-like -2.04162
FASTKD1 FAST kinase domains 1 -2.03938
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -2.02939
DCAF15 DDB1 and CUL4 associated factor 15 -2.02418
GPR153 G protein-coupled receptor 153 -2.01804