RAD1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description RAD1 checkpoint DNA exonuclease|This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009] (NCBI Entrez Gene Database, 5810)
External Link http://www.ncbi.nlm.nih.gov/gene/5810
Similar Terms
Downloads & Tools

Genes

47 interacting proteins for RAD1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ATR ATR serine/threonine kinase
ATRX alpha thalassemia/mental retardation syndrome X-linked
C17ORF70 chromosome 17 open reading frame 70
COPS5 COP9 signalosome subunit 5
CSNK2A1 casein kinase 2, alpha 1 polypeptide
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
FANCA Fanconi anemia, complementation group A
FANCB Fanconi anemia, complementation group B
FANCC Fanconi anemia, complementation group C
FANCD2 Fanconi anemia, complementation group D2
FANCE Fanconi anemia, complementation group E
FANCF Fanconi anemia, complementation group F
FANCG Fanconi anemia, complementation group G
FANCI Fanconi anemia, complementation group I
FANCL Fanconi anemia, complementation group L
FEN1 flap structure-specific endonuclease 1
HES1 hes family bHLH transcription factor 1
HUS1 HUS1 checkpoint homolog (S. pombe)
HUS1B HUS1 checkpoint homolog b (S. pombe)
LIG1 ligase I, DNA, ATP-dependent
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MCM2 minichromosome maintenance complex component 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MSH6 mutS homolog 6
NBN nibrin
PARK2 parkin RBR E3 ubiquitin protein ligase
POLB polymerase (DNA directed), beta
RAD17 RAD17 homolog (S. pombe)
RAD9A RAD9 homolog A (S. pombe)
RAD9B RAD9 homolog B (S. pombe)
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
SFN stratifin
UBC ubiquitin C
UBE2T ubiquitin-conjugating enzyme E2T
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta