RAD21 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description RAD21 homolog (S. pombe)|The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5885)
External Link https://ncbi.nlm.nih.gov/gene/5885
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Genes

499 genes differentially expressed following the RAD21 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SFN stratifin 0.0497173
FRZB frizzled-related protein 0.0364771
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.0359454
SPP1 secreted phosphoprotein 1 0.0355816
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.034465
AQP3 aquaporin 3 (Gill blood group) 0.0306037
PLIN2 perilipin 2 0.0283095
HDGFL3 HDGF like 3 0.0269102
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.0267593
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 0.0266082
KRT14 keratin 14, type I 0.0263266
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.0259939
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0253246
SIRT3 sirtuin 3 0.0247508
GPER1 G protein-coupled estrogen receptor 1 0.0234504
IFITM1 interferon induced transmembrane protein 1 0.0230112
H1-2 H1.2 linker histone, cluster member 0.0228603
PHKA1 phosphorylase kinase, alpha 1 (muscle) 0.0224499
KRT5 keratin 5, type II 0.0222315
S100P S100 calcium binding protein P 0.0220261
SPRR1B small proline-rich protein 1B 0.0218868
TIMP3 TIMP metallopeptidase inhibitor 3 0.0217747
AKR1C3 aldo-keto reductase family 1, member C3 0.0214824
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.0213322
CTSK cathepsin K 0.0206244
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.019926
CDC20 cell division cycle 20 0.0197269
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.019521
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.0193464
ISG15 ISG15 ubiquitin-like modifier 0.0193133
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.0191948
EGFR epidermal growth factor receptor 0.0189624
POSTN periostin, osteoblast specific factor 0.0188631
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.0187423
ITGB4 integrin, beta 4 0.0185827
HIST1H2BD histone cluster 1, H2bd 0.0185622
PEX11A peroxisomal biogenesis factor 11 alpha 0.0185134
HSPB8 heat shock 22kDa protein 8 0.0183399
IL1B interleukin 1, beta 0.0181907
DMBT1 deleted in malignant brain tumors 1 0.0178681
A2M alpha-2-macroglobulin 0.0176544
AKR1C2 aldo-keto reductase family 1, member C2 0.01758
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.0170217
TFPI2 tissue factor pathway inhibitor 2 0.017
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.0168818
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.0168616
GARS1 glycyl-tRNA synthetase 1 0.0168104
CTNND1 catenin (cadherin-associated protein), delta 1 0.0167721
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.0167641
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.0167481
MME membrane metallo-endopeptidase 0.016495
SPINK1 serine peptidase inhibitor, Kazal type 1 0.0164827
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.0164361
GMPR guanosine monophosphate reductase 0.0163924
COCH cochlin 0.0163817
ABHD6 abhydrolase domain containing 6 0.0162506
ADGRG2 adhesion G protein-coupled receptor G2 0.0161631
AQP1 aquaporin 1 (Colton blood group) 0.0161143
ACP5 acid phosphatase 5, tartrate resistant 0.0161036
TMC5 transmembrane channel-like 5 0.0160847
HIST1H2AC histone cluster 1, H2ac 0.0159284
GDF15 growth differentiation factor 15 0.0158814
PLPP3 phospholipid phosphatase 3 0.0158617
MEIS2 Meis homeobox 2 0.0158607
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.0158336
MDK midkine (neurite growth-promoting factor 2) 0.0158002
PDLIM3 PDZ and LIM domain 3 0.015744
RGS5 regulator of G-protein signaling 5 0.0156301
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.0156087
HTRA1 HtrA serine peptidase 1 0.0156068
AKR1C1 aldo-keto reductase family 1, member C1 0.0155801
AKAP12 A kinase (PRKA) anchor protein 12 0.0155692
CXCL14 chemokine (C-X-C motif) ligand 14 0.0155134
CLGN calmegin 0.0154404
PPT1 palmitoyl-protein thioesterase 1 0.0154399
SUB1 SUB1 homolog (S. cerevisiae) 0.0154208
MMP12 matrix metallopeptidase 12 0.0153588
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.0153175
ANK2 ankyrin 2, neuronal 0.0152684
HMOX1 heme oxygenase 1 0.0152371
KRT6A keratin 6A, type II 0.0151888
C1QA complement component 1, q subcomponent, A chain 0.0150682
HOPX HOP homeobox 0.0149821
RPIA ribose 5-phosphate isomerase A 0.0149112
EDNRA endothelin receptor type A 0.0148952
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.0148637
NBAS neuroblastoma amplified sequence 0.0148522
COL3A1 collagen, type III, alpha 1 0.0147684
FN1 fibronectin 1 0.0147675
MOXD1 monooxygenase, DBH-like 1 0.0146592
PTP4A3 protein tyrosine phosphatase type IVA, member 3 0.0145483
SPARCL1 SPARC-like 1 (hevin) 0.0145206
IL17RB interleukin 17 receptor B 0.0144479
SPRR1A small proline-rich protein 1A 0.0144306
FHL1 four and a half LIM domains 1 0.0144142
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 0.0142297
METTL9 methyltransferase like 9 0.0142139
CCL4 chemokine (C-C motif) ligand 4 0.0142065
MREG melanoregulin 0.0141482
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.0140997
GLUL glutamate-ammonia ligase 0.0140617
MSX1 msh homeobox 1 0.0139625
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.0138888
LPAR6 lysophosphatidic acid receptor 6 0.0137855
CLDN10 claudin 10 0.0137751
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.0137628
ITGA6 integrin, alpha 6 0.0137572
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.0135912
CCRL2 chemokine (C-C motif) receptor-like 2 0.0135199
AGR2 anterior gradient 2 0.0134616
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.0134519
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0134104
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 0.0133154
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.0132952
RRAGD Ras-related GTP binding D 0.0131968
MXRA7 matrix-remodelling associated 7 0.013178
FZD4 frizzled class receptor 4 0.0131407
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.013119
NELL2 NEL-like 2 (chicken) 0.0130722
C3 complement component 3 0.0130639
IFRD2 interferon-related developmental regulator 2 0.0130259
SLC16A4 solute carrier family 16, member 4 0.013011
RAD51C RAD51 paralog C 0.0129769
IGLL1 immunoglobulin lambda-like polypeptide 1 0.0129083
IL1RN interleukin 1 receptor antagonist 0.0128446
HIST1H2BH histone cluster 1, H2bh 0.0128001
PUDP pseudouridine 5'-phosphatase 0.0127717
PLVAP plasmalemma vesicle associated protein 0.0127471
LYPD1 LY6/PLAUR domain containing 1 0.0127426
CD320 CD320 molecule 0.0127393
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0127172
PI3 peptidase inhibitor 3, skin-derived 0.0127099
ADORA2B adenosine A2b receptor 0.0126608
ASPN asporin 0.0126593
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2) 0.0126319
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.0126301
DHDDS dehydrodolichyl diphosphate synthase 0.0126226
LGALS2 lectin, galactoside-binding, soluble, 2 0.01259
SAT1 spermidine/spermine N1-acetyltransferase 1 0.0125863
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.0125861
HSPA2 heat shock 70kDa protein 2 0.0125786
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.0125784
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.0125306
PBX2P1 pre-B-cell leukemia homeobox 2 pseudogene 1 0.0125253
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 0.0125237
MACROH2A2 macroH2A.2 histone 0.01251
NARF nuclear prelamin A recognition factor 0.0124545
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.0124545
GJA1 gap junction protein, alpha 1, 43kDa 0.0124403
TMEM140 transmembrane protein 140 0.0124248
TSPAN6 tetraspanin 6 0.0123696
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 0.0123381
XIC X chromosome inactivation center 0.0123065
MMP11 matrix metallopeptidase 11 0.0123023
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.012271
ISYNA1 inositol-3-phosphate synthase 1 0.0122179
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.0122062
STC2 stanniocalcin 2 0.0122038
SATB2 SATB homeobox 2 0.0121978
CYTL1 cytokine-like 1 0.012159
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.012134
LPCAT1 lysophosphatidylcholine acyltransferase 1 0.0120692
LTBP1 latent transforming growth factor beta binding protein 1 0.0120504
UROD uroporphyrinogen decarboxylase 0.012044
PLN phospholamban 0.0120146
CHKB choline kinase beta 0.0120082
MFAP4 microfibrillar-associated protein 4 0.0119993
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 0.0119339
ZFP36L1 ZFP36 ring finger protein-like 1 0.0119221
RSAD2 radical S-adenosyl methionine domain containing 2 0.0118373
CREB1 cAMP responsive element binding protein 1 0.0117996
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.0117923
GYG2 glycogenin 2 0.0117692
GPX4 glutathione peroxidase 4 0.0117636
MYBPC1 myosin binding protein C, slow type 0.0116673
GNAS GNAS complex locus 0.0116575
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0116506
TTC39A tetratricopeptide repeat domain 39A 0.0116286
KANK2 KN motif and ankyrin repeat domains 2 0.0115674
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 0.0115642
IGFBP5 insulin-like growth factor binding protein 5 0.0115188
WBP5 WW domain binding protein 5 0.0115125
JAG1 jagged 1 0.0115024
ICAM2 intercellular adhesion molecule 2 0.0114956
GEM GTP binding protein overexpressed in skeletal muscle 0.0114823
ARMCX1 armadillo repeat containing, X-linked 1 0.0114498
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.0114347
KRT16 keratin 16, type I 0.0114115
DLK1 delta-like 1 homolog (Drosophila) 0.011394
MN1 meningioma (disrupted in balanced translocation) 1 0.0113702
MYLK myosin light chain kinase 0.0113458
ASPA aspartoacylase 0.0113237
CEL carboxyl ester lipase 0.0113138
FTH1 ferritin, heavy polypeptide 1 0.011227
IFI44L interferon-induced protein 44-like 0.0111853
COL1A2 collagen, type I, alpha 2 0.0111736
MED13 mediator complex subunit 13 0.0111709
CKAP4 cytoskeleton-associated protein 4 0.0110592
COG7 component of oligomeric golgi complex 7 0.0110359
EIF5 eukaryotic translation initiation factor 5 0.0109878
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.0109825
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.0109661
KRT13 keratin 13, type I 0.0109651
GRWD1 glutamate-rich WD repeat containing 1 0.0109293
ANGPTL2 angiopoietin-like 2 0.0109134
SLC35F2 solute carrier family 35, member F2 0.0108841
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.0108671
GATAD2A GATA zinc finger domain containing 2A 0.010865
BARD1 BRCA1 associated RING domain 1 0.0108638
C1ORF54 chromosome 1 open reading frame 54 0.0108552
JAKMIP2 janus kinase and microtubule interacting protein 2 0.010761
SPRR3 small proline-rich protein 3 0.0107592
IFITM3 interferon induced transmembrane protein 3 0.0107542
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.0106872
JCHAIN joining chain of multimeric IgA and IgM 0.0106853
ZDHHC4 zinc finger, DHHC-type containing 4 0.0106677
NADK NAD kinase 0.0106594
DGAT1 diacylglycerol O-acyltransferase 1 0.0106366
FLT1 fms-related tyrosine kinase 1 0.0106234
AOC3 amine oxidase, copper containing 3 0.0106058
PEG10 paternally expressed 10 0.010603
KRT15 keratin 15, type I 0.0105975
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 0.0105841
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 0.0105604
JAM3 junctional adhesion molecule 3 0.0105293
GCLC glutamate-cysteine ligase, catalytic subunit 0.0104797
SKAP2 src kinase associated phosphoprotein 2 0.0104795
PDGFD platelet derived growth factor D 0.010478
SHB Src homology 2 domain containing adaptor protein B 0.010414
HOXA5 homeobox A5 0.010393
RANBP1 RAN binding protein 1 0.0103832
CD48 CD48 molecule 0.0103816
TAC1 tachykinin, precursor 1 0.0103767
SURF1 surfeit 1 0.0103738
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.0103704
CD38 CD38 molecule 0.0103626
TGFB1 transforming growth factor, beta 1 0.0103478
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.0103289
WASHC4 WASH complex subunit 4 0.0103166
ARG2 arginase 2 0.01031
SORBS1 sorbin and SH3 domain containing 1 0.0102913
CPE carboxypeptidase E 0.0102865
NPY1R neuropeptide Y receptor Y1 0.0102803
IDO1 indoleamine 2,3-dioxygenase 1 0.0102738
SPINK5 serine peptidase inhibitor, Kazal type 5 0.0102708
SLAMF7 SLAM family member 7 0.0102502
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 0.0102314
JMJD6 jumonji domain containing 6 0.0102287
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.0101617
S100A2 S100 calcium binding protein A2 0.0101422

decreased expression

Symbol Name Standardized Value
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.0334661
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.028793
MAP7 microtubule-associated protein 7 -0.0283056
KRT7 keratin 7, type II -0.0281018
EPN2 epsin 2 -0.0279829
TACSTD2 tumor-associated calcium signal transducer 2 -0.0263928
BASP1 brain abundant, membrane attached signal protein 1 -0.0249116
MSLN mesothelin -0.0235019
SGK1 serum/glucocorticoid regulated kinase 1 -0.0225662
COL9A3 collagen, type IX, alpha 3 -0.0219251
FRY furry homolog (Drosophila) -0.021092
PDGFA platelet-derived growth factor alpha polypeptide -0.0194571
RFX5 regulatory factor X, 5 (influences HLA class II expression) -0.0187012
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) -0.0186899
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0186486
TLE4 transducin-like enhancer of split 4 -0.0185679
S100A10 S100 calcium binding protein A10 -0.0185498
GUCY2C guanylate cyclase 2C -0.0184037
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) -0.0183207
MAMLD1 mastermind-like domain containing 1 -0.018163
APLP2 amyloid beta (A4) precursor-like protein 2 -0.0181482
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) -0.0181366
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -0.0180354
F13A1 coagulation factor XIII, A1 polypeptide -0.018034
BACE2 beta-site APP-cleaving enzyme 2 -0.0177953
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -0.017367
PGM1 phosphoglucomutase 1 -0.0173643
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.017306
AHNAK AHNAK nucleoprotein -0.0171232
CST3 cystatin C -0.017119
ATP8B4 ATPase, class I, type 8B, member 4 -0.0169709
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.0168473
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -0.0164218
CRIP2 cysteine-rich protein 2 -0.0164149
ERBB2 erb-b2 receptor tyrosine kinase 2 -0.0163952
SFRP1 secreted frizzled-related protein 1 -0.0162375
AZU1 azurocidin 1 -0.0161821
CRIP1 cysteine-rich protein 1 (intestinal) -0.0160038
RNH1 ribonuclease/angiogenin inhibitor 1 -0.0159959
APOD apolipoprotein D -0.0158827
ATP10D ATPase, class V, type 10D -0.0158675
IDI1 isopentenyl-diphosphate delta isomerase 1 -0.0158586
LY75 lymphocyte antigen 75 -0.0157743
CXCL5 chemokine (C-X-C motif) ligand 5 -0.0157642
TAGLN2 transgelin 2 -0.0157297
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.0157078
ADAM28 ADAM metallopeptidase domain 28 -0.0155656
CXCL2 chemokine (C-X-C motif) ligand 2 -0.0155512
NDRG1 N-myc downstream regulated 1 -0.0154872
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -0.0154159
CHEK1 checkpoint kinase 1 -0.0154111
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0154038
XPO7 exportin 7 -0.0153762
CXCL6 chemokine (C-X-C motif) ligand 6 -0.0153279
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.0152937
SPON2 spondin 2, extracellular matrix protein -0.0152521
DDIT4 DNA-damage-inducible transcript 4 -0.0151187
MT1M metallothionein 1M -0.0151064
CST6 cystatin E/M -0.0150699
FKBP14 FK506 binding protein 14, 22 kDa -0.0150529
DSTN destrin (actin depolymerizing factor) -0.0149993
MRPS2 mitochondrial ribosomal protein S2 -0.014951
KLK10 kallikrein-related peptidase 10 -0.0149251
SH3YL1 SH3 and SYLF domain containing 1 -0.0149236
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.0148366
TLR4 toll-like receptor 4 -0.0147794
EPHA3 EPH receptor A3 -0.0146985
FNBP1 formin binding protein 1 -0.0146456
COL9A2 collagen, type IX, alpha 2 -0.0145443
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -0.0145328
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.0145005
GSN gelsolin -0.0144647
S100A12 S100 calcium binding protein A12 -0.0144615
L1CAM L1 cell adhesion molecule -0.014443
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.0144142
SOSTDC1 sclerostin domain containing 1 -0.0143623
CCNE2 cyclin E2 -0.014248
DPYSL3 dihydropyrimidinase-like 3 -0.0141484
SHROOM2 shroom family member 2 -0.0141275
EPHA4 EPH receptor A4 -0.0141262
C6 complement component 6 -0.0141156
SELL selectin L -0.0140894
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0140672
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0138853
IL6 interleukin 6 -0.0138103
INSIG1 insulin induced gene 1 -0.0137856
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.0137258
KIF14 kinesin family member 14 -0.0135539
CIAO3 cytosolic iron-sulfur assembly component 3 -0.0134977
FOXC1 forkhead box C1 -0.0134851
RHOB ras homolog family member B -0.013479
TRPS1 trichorhinophalangeal syndrome I -0.0134683
LPXN leupaxin -0.0134281
APMAP adipocyte plasma membrane associated protein -0.0134052
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -0.0133397
VLDLR very low density lipoprotein receptor -0.0133079
PLS3 plastin 3 -0.0132711
RBKS ribokinase -0.0132641
S100A11 S100 calcium binding protein A11 -0.0132462
EGR3 early growth response 3 -0.0132389
CSRP1 cysteine and glycine-rich protein 1 -0.0131882
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.013184
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0130981
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.0130927
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0130865
INPP1 inositol polyphosphate-1-phosphatase -0.0130469
CFH complement factor H -0.0130427
ADGRL2 adhesion G protein-coupled receptor L2 -0.0130406
RNASE3 ribonuclease, RNase A family, 3 -0.0129978
AHI1 Abelson helper integration site 1 -0.012924
MSMO1 methylsterol monooxygenase 1 -0.0129166
XYLT1 xylosyltransferase I -0.0129166
CCR7 chemokine (C-C motif) receptor 7 -0.0128858
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0128625
LINC00623 long intergenic non-protein coding RNA 623 -0.0128386
CLDN1 claudin 1 -0.0128073
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -0.0127824
TARP TCR gamma alternate reading frame protein -0.0127563
PLPP2 phospholipid phosphatase 2 -0.0127119
KLK11 kallikrein-related peptidase 11 -0.0126932
PHLDA2 pleckstrin homology-like domain, family A, member 2 -0.012625
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -0.0126169
ZBED2 zinc finger, BED-type containing 2 -0.0125726
NOTCH2 notch 2 -0.012565
DHCR24 24-dehydrocholesterol reductase -0.0125201
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.0124762
PTCH1 patched 1 -0.012472
SOGA1 suppressor of glucose, autophagy associated 1 -0.01244
NAV3 neuron navigator 3 -0.0124353
ELANE elastase, neutrophil expressed -0.0123703
NXN nucleoredoxin -0.0123703
TARBP1 TAR (HIV-1) RNA binding protein 1 -0.0123314
PRTN3 proteinase 3 -0.0123148
TRPM4 transient receptor potential cation channel, subfamily M, member 4 -0.0123145
FPGS folylpolyglutamate synthase -0.0123075
GAB2 GRB2-associated binding protein 2 -0.0122989
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 -0.0122789
DST dystonin -0.0122621
STK17A serine/threonine kinase 17a -0.0121813
PDLIM2 PDZ and LIM domain 2 (mystique) -0.0121261
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) -0.0121019
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.0120725
CLEC11A C-type lectin domain family 11, member A -0.0120619
WASF3 WAS protein family, member 3 -0.0120395
KLK6 kallikrein-related peptidase 6 -0.0120179
RAD23B RAD23 homolog B (S. cerevisiae) -0.0119857
PAX8 paired box 8 -0.0119795
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.0119686
NCALD neurocalcin delta -0.0119667
CRP C-reactive protein, pentraxin-related -0.0119427
SPTSSA serine palmitoyltransferase, small subunit A -0.0119314
ACAT2 acetyl-CoA acetyltransferase 2 -0.0119111
C7 complement component 7 -0.0118793
EGR1 early growth response 1 -0.0118609
BTG1 B-cell translocation gene 1, anti-proliferative -0.0118424
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.0118365
HEATR1 HEAT repeat containing 1 -0.011835
IRAK3 interleukin-1 receptor-associated kinase 3 -0.0117997
PBK PDZ binding kinase -0.0117772
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -0.0117672
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0117524
GAS7 growth arrest-specific 7 -0.0117098
STMN2 stathmin 2 -0.0116369
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.0116077
KRT8 keratin 8, type II -0.0116061
FZD6 frizzled class receptor 6 -0.0115751
KCNK1 potassium channel, two pore domain subfamily K, member 1 -0.0115716
SLC38A2 solute carrier family 38, member 2 -0.0115681
FLT3 fms-related tyrosine kinase 3 -0.0115674
PHF20 PHD finger protein 20 -0.0115633
GPC1 glypican 1 -0.0115059
ELF5 E74-like factor 5 (ets domain transcription factor) -0.0114868
FOSL2 FOS-like antigen 2 -0.0114277
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.0113763
RPL36 ribosomal protein L36 -0.0113184
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.0113109
UVRAG UV radiation resistance associated -0.0112806
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0112619
HDAC4 histone deacetylase 4 -0.0112331
HOXC6 homeobox C6 -0.0112301
ECT2 epithelial cell transforming 2 -0.0112029
ELP1 elongator acetyltransferase complex subunit 1 -0.0111909
TSPO translocator protein (18kDa) -0.0111693
LOC105375355 uroplakin-3b -0.0111673
CCN2 cellular communication network factor 2 -0.0111618
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -0.0111458
GLUD2 glutamate dehydrogenase 2 -0.0111283
TFF3 trefoil factor 3 (intestinal) -0.0110703
ETNK1 ethanolamine kinase 1 -0.0110668
PAWR PRKC, apoptosis, WT1, regulator -0.0110633
COL18A1 collagen, type XVIII, alpha 1 -0.0110363
MYB v-myb avian myeloblastosis viral oncogene homolog -0.0110021
SOX17 SRY (sex determining region Y)-box 17 -0.0109809
C4BPB complement component 4 binding protein, beta -0.0109787
MYRF myelin regulatory factor -0.0109612
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -0.0109583
CYB5R2 cytochrome b5 reductase 2 -0.010949
TBC1D4 TBC1 domain family, member 4 -0.0109268
COTL1 coactosin-like F-actin binding protein 1 -0.0109092
CKAP2 cytoskeleton associated protein 2 -0.0109036
KLF9 Kruppel-like factor 9 -0.0108861
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -0.0108444
NCAPD3 non-SMC condensin II complex, subunit D3 -0.0108435
ACSL3 acyl-CoA synthetase long-chain family member 3 -0.0107984
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1 -0.0107706
SWAP70 SWAP switching B-cell complex 70kDa subunit -0.010663
C3ORF14 chromosome 3 open reading frame 14 -0.0106583
TUBB6 tubulin, beta 6 class V -0.0106413
CAST calpastatin -0.0105929
PLG plasminogen -0.0105669
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0105639
TMSB15A thymosin beta 15a -0.0105392
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -0.0105279
GJB1 gap junction protein, beta 1, 32kDa -0.0105264
SRPX sushi-repeat containing protein, X-linked -0.0105164
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -0.0104564
ANXA5 annexin A5 -0.0104555
CTSV cathepsin V -0.0104518
NOTCH2NL notch 2 N-terminal like -0.0104398
AMACR alpha-methylacyl-CoA racemase -0.0104389
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.0104166
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -0.0103907
LMO3 LIM domain only 3 (rhombotin-like 2) -0.0103891
OSTF1 osteoclast stimulating factor 1 -0.0103672
NBPF10 neuroblastoma breakpoint family, member 10 -0.010363
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 -0.0103608
FOXN3 forkhead box N3 -0.0103591
RBBP7 retinoblastoma binding protein 7 -0.010356
SDC2 syndecan 2 -0.0103451
PPA2 pyrophosphatase (inorganic) 2 -0.0103305
HOXC10 homeobox C10 -0.0102953
BTBD3 BTB (POZ) domain containing 3 -0.0102735
C9 complement component 9 -0.0102532
HAL histidine ammonia-lyase -0.0102528
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 -0.0102454
TGFBR3 transforming growth factor, beta receptor III -0.0102443
RECQL RecQ helicase-like -0.0102387
CCL19 chemokine (C-C motif) ligand 19 -0.0102249
FAM3C family with sequence similarity 3, member C -0.0102202
RAP1GAP2 RAP1 GTPase activating protein 2 -0.0102145
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 -0.0101995
LAMP5 lysosomal-associated membrane protein family, member 5 -0.0101888
PXN paxillin -0.0101767
RUNX1 runt-related transcription factor 1 -0.0101626
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 -0.0101603
SOX10 SRY (sex determining region Y)-box 10 -0.0101593
FOXE1 forkhead box E1 -0.0101574
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.0101459
MMP10 matrix metallopeptidase 10 -0.0101459