| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | RAD51 recombinase|The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009] (NCBI Entrez Gene Database, 5888) |
| External Link | https://ncbi.nlm.nih.gov/gene/5888 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the RAD51 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHP1 | calcineurin-like EF-hand protein 1 | 0.0168374 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.0155834 |
| MAGEA3 | melanoma antigen family A3 | 0.0145792 |
| MGP | matrix Gla protein | 0.0138149 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.0137872 |
| CFD | complement factor D (adipsin) | 0.0132206 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.0128703 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0127838 |
| APOD | apolipoprotein D | 0.0125902 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.0123319 |
| BCHE | butyrylcholinesterase | 0.0122195 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0121518 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0120672 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.011772 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.0112988 |
| CFH | complement factor H | 0.0112495 |
| SRPX | sushi-repeat containing protein, X-linked | 0.0111839 |
| CFB | complement factor B | 0.0110709 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.0108113 |
| C3 | complement component 3 | 0.0107918 |
| CHRDL1 | chordin-like 1 | 0.0106446 |
| COL15A1 | collagen, type XV, alpha 1 | 0.0105562 |
| LCN2 | lipocalin 2 | 0.0101796 |
| PMP22 | peripheral myelin protein 22 | 0.0101733 |
| CES1 | carboxylesterase 1 | 0.0100818 |
| PLTP | phospholipid transfer protein | 0.00978025 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 0.00970011 |
| ASPN | asporin | 0.00965563 |
| STC1 | stanniocalcin 1 | 0.00951483 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog | 0.00945798 |
| DCT | dopachrome tautomerase | 0.00945792 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00945507 |
| CD163 | CD163 molecule | 0.00944756 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00936879 |
| ARHGEF40 | Rho guanine nucleotide exchange factor (GEF) 40 | 0.00927053 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00922511 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00921392 |
| BEX1 | brain expressed, X-linked 1 | 0.00916265 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00913661 |
| OPHN1 | oligophrenin 1 | 0.00908174 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00907397 |
| BEX4 | brain expressed, X-linked 4 | 0.00898985 |
| DCN | decorin | 0.00894274 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00884271 |
| MX2 | MX dynamin-like GTPase 2 | 0.00883427 |
| DES | desmin | 0.00876341 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00876232 |
| MAOA | monoamine oxidase A | 0.00876152 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.008737 |
| SYNM | synemin, intermediate filament protein | 0.00873687 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 0.00863112 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.00858922 |
| NRCAM | neuronal cell adhesion molecule | 0.00856537 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.00854784 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.00854222 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00854218 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.00853318 |
| WFDC1 | WAP four-disulfide core domain 1 | 0.00847839 |
| CDC42SE1 | CDC42 small effector 1 | 0.00845148 |
| PLN | phospholamban | 0.00834022 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00832327 |
| SNX10 | sorting nexin 10 | 0.008298 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00810441 |
| PEG3 | paternally expressed 3 | 0.00809708 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 0.00806302 |
| RNF144A | ring finger protein 144A | 0.00803854 |
| SORD | sorbitol dehydrogenase | 0.00801359 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00791404 |
| XAF1 | XIAP associated factor 1 | 0.00774206 |
| THBS2 | thrombospondin 2 | 0.00773681 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00771139 |
| FASN | fatty acid synthase | 0.00771031 |
| C1S | complement component 1, s subcomponent | 0.00762487 |
| NID2 | nidogen 2 (osteonidogen) | 0.00761381 |
| SMS | spermine synthase | 0.00758605 |
| FN1 | fibronectin 1 | 0.00755594 |
| NID1 | nidogen 1 | 0.007538 |
| TLR4 | toll-like receptor 4 | 0.00753711 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.00752856 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 | 0.00752711 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00748163 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00747937 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00745142 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.00744496 |
| CTSK | cathepsin K | 0.00743027 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00742321 |
| C7 | complement component 7 | 0.00741953 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.007399 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00737958 |
| CLU | clusterin | 0.00737756 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | 0.00733659 |
| KYNU | kynureninase | 0.00733296 |
| LMOD1 | leiomodin 1 (smooth muscle) | 0.0073208 |
| MORC4 | MORC family CW-type zinc finger 4 | 0.00731295 |
| CNTN1 | contactin 1 | 0.00730109 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00729455 |
| MAGEA12 | melanoma antigen family A12 | 0.00727782 |
| S100A9 | S100 calcium binding protein A9 | 0.00724787 |
| LAMA2 | laminin, alpha 2 | 0.0072426 |
| RELN | reelin | 0.00723943 |
| TNS1 | tensin 1 | 0.00722488 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.0072021 |
| S100B | S100 calcium binding protein B | 0.00719599 |
| COL4A5 | collagen, type IV, alpha 5 | 0.00719133 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00718544 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | 0.00715915 |
| PLIN2 | perilipin 2 | 0.00715432 |
| WBP5 | WW domain binding protein 5 | 0.00713791 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 0.00711913 |
| SRPK1 | SRSF protein kinase 1 | 0.00707943 |
| ANXA4 | annexin A4 | 0.00704396 |
| AGR2 | anterior gradient 2 | 0.00703192 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00702194 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | 0.00698585 |
| PLAT | plasminogen activator, tissue | 0.00694298 |
| MPDZ | multiple PDZ domain protein | 0.00684427 |
| DMXL2 | Dmx-like 2 | 0.00684118 |
| LAMA4 | laminin, alpha 4 | 0.00683359 |
| UPK1B | uroplakin 1B | 0.00682577 |
| MAOB | monoamine oxidase B | 0.0068215 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | 0.00678689 |
| FGL1 | fibrinogen-like 1 | 0.0067833 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00677974 |
| IL1B | interleukin 1, beta | 0.0067688 |
| C3AR1 | complement component 3a receptor 1 | 0.0067615 |
| NOTCH2NL | notch 2 N-terminal like | 0.00675376 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.00674967 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00673193 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00671059 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | 0.0066349 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0066119 |
| COLEC12 | collectin sub-family member 12 | 0.00660759 |
| FCGBP | Fc fragment of IgG binding protein | 0.00660601 |
| METTL7A | methyltransferase like 7A | 0.00659028 |
| QKI | QKI, KH domain containing, RNA binding | 0.00658833 |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.00658083 |
| NAV3 | neuron navigator 3 | 0.00655448 |
| FGF13 | fibroblast growth factor 13 | 0.0065369 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00650779 |
| MITF | microphthalmia-associated transcription factor | 0.00650742 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00644709 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.00641223 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | 0.00640626 |
| PLP1 | proteolipid protein 1 | 0.00638161 |
| SNAI2 | snail family zinc finger 2 | 0.00638073 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00638013 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00636315 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00635688 |
| TSPAN8 | tetraspanin 8 | 0.00635638 |
| GAS1 | growth arrest-specific 1 | 0.00628543 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 | 0.0062843 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 | 0.00626962 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.00626199 |
| NCKAP1 | NCK-associated protein 1 | 0.00625871 |
| SERINC5 | serine incorporator 5 | 0.00624634 |
| REG1A | regenerating islet-derived 1 alpha | 0.00621922 |
| STAT5A | signal transducer and activator of transcription 5A | 0.00620565 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00620353 |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.00618341 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.00617741 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.00616998 |
| NRN1 | neuritin 1 | 0.00616965 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.00616563 |
| CSTA | cystatin A (stefin A) | 0.00615948 |
| NPAS2 | neuronal PAS domain protein 2 | 0.00615532 |
| IFI44L | interferon-induced protein 44-like | 0.00614589 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00613812 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00612321 |
| MXRA5 | matrix-remodelling associated 5 | 0.006119 |
| C1R | complement component 1, r subcomponent | 0.00611805 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00611341 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00610554 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 0.00607058 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00606903 |
| C1QB | complement component 1, q subcomponent, B chain | 0.00606654 |
| FXYD6 | FXYD domain containing ion transport regulator 6 | 0.00604416 |
| HAL | histidine ammonia-lyase | 0.00603 |
| FAM8A1 | family with sequence similarity 8, member A1 | 0.00602659 |
| ANGPTL2 | angiopoietin-like 2 | 0.0060184 |
| PIP | prolactin-induced protein | 0.00601637 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00601271 |
| TSPYL5 | TSPY-like 5 | 0.00600664 |
| RGS2 | regulator of G-protein signaling 2 | 0.0060043 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.00600109 |
| KAT2B | K(lysine) acetyltransferase 2B | 0.0059693 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00596437 |
| CD4 | CD4 molecule | 0.00595671 |
| DUSP5 | dual specificity phosphatase 5 | 0.00595176 |
| AHNAK | AHNAK nucleoprotein | 0.00595028 |
| GPX2 | glutathione peroxidase 2 | 0.00594527 |
| COMT | catechol-O-methyltransferase | 0.00594366 |
| SMTN | smoothelin | 0.00594317 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00594034 |
| AEBP1 | AE binding protein 1 | 0.00594027 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00591401 |
| CNN1 | calponin 1, basic, smooth muscle | 0.00589408 |
| TYR | tyrosinase | 0.00587518 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 | 0.00587141 |
| PIR | pirin (iron-binding nuclear protein) | 0.00585392 |
| DEFB1 | defensin, beta 1 | 0.0058522 |
| COL1A2 | collagen, type I, alpha 2 | 0.0058409 |
| DUSP4 | dual specificity phosphatase 4 | 0.00583817 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.00583445 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | 0.0058284 |
| CENPU | centromere protein U | 0.00582369 |
| INSM1 | insulinoma-associated 1 | 0.00581752 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00581604 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.0058092 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00579988 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00578529 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | 0.00578511 |
| LOC105375355 | uroplakin-3b | 0.00578463 |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.00578326 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00576737 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 | 0.00575029 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00574102 |
| GPX3 | glutathione peroxidase 3 | 0.00573273 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.00572845 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 | 0.0057184 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0057162 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00571517 |
| AGTR1 | angiotensin II receptor, type 1 | 0.00571058 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.00570294 |
| FADS1 | fatty acid desaturase 1 | 0.00570234 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00569322 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00568588 |
| EPCAM | epithelial cell adhesion molecule | 0.00568386 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00566926 |
| KLHL21 | kelch-like family member 21 | 0.00566213 |
| OLFML2A | olfactomedin-like 2A | 0.00564737 |
| BTG2 | BTG family, member 2 | 0.00563347 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00563095 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.00562488 |
| FYB1 | FYN binding protein 1 | 0.0056178 |
| ARHGAP6 | Rho GTPase activating protein 6 | 0.00560988 |
| AOC3 | amine oxidase, copper containing 3 | 0.0056072 |
| S100A8 | S100 calcium binding protein A8 | 0.00560275 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 | 0.00559424 |
| IER5 | immediate early response 5 | 0.00557846 |
| TOB1 | transducer of ERBB2, 1 | 0.0055748 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.00557328 |
| MEIS1 | Meis homeobox 1 | 0.00557196 |
| MX1 | MX dynamin-like GTPase 1 | 0.00556064 |
| RRAS | related RAS viral (r-ras) oncogene homolog | 0.00555739 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00553921 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00553378 |
| TNC | tenascin C | 0.00553364 |
| BCL2A1 | BCL2-related protein A1 | 0.00552032 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00550553 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SIRT3 | sirtuin 3 | -0.015707 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.0136736 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.0126124 |
| CA2 | carbonic anhydrase II | -0.011905 |
| ADI1 | acireductone dioxygenase 1 | -0.0115897 |
| KRT14 | keratin 14, type I | -0.0114691 |
| STC2 | stanniocalcin 2 | -0.0114136 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0113671 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0112026 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0111292 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.0111091 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | -0.0106204 |
| E2F2 | E2F transcription factor 2 | -0.010509 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | -0.0103168 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.0100824 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00975276 |
| PRR7 | proline rich 7 (synaptic) | -0.00971554 |
| NPR3 | natriuretic peptide receptor 3 | -0.00923532 |
| CCN2 | cellular communication network factor 2 | -0.00896955 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00887171 |
| MAP7 | microtubule-associated protein 7 | -0.00878419 |
| ANXA3 | annexin A3 | -0.00869 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00865353 |
| AUTS2 | autism susceptibility candidate 2 | -0.00823547 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00815018 |
| DNTT | DNA nucleotidylexotransferase | -0.00810447 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00796046 |
| TOX | thymocyte selection-associated high mobility group box | -0.00794544 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00792734 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00790503 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00784213 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -0.00765822 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | -0.00755734 |
| SDC1 | syndecan 1 | -0.0074926 |
| KRT17 | keratin 17, type I | -0.00744147 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00732114 |
| KRT16 | keratin 16, type I | -0.0072585 |
| TLE4 | transducin-like enhancer of split 4 | -0.00724899 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00716745 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | -0.00710988 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.00706971 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.007068 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00698233 |
| ENOPH1 | enolase-phosphatase 1 | -0.00692376 |
| FOXG1 | forkhead box G1 | -0.00689501 |
| ARPP21 | cAMP-regulated phosphoprotein, 21kDa | -0.00684476 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00680488 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0068037 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00679841 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | -0.00678545 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0067671 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00670829 |
| PRMT1 | protein arginine methyltransferase 1 | -0.0066898 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00652351 |
| AREG | amphiregulin | -0.00649574 |
| DAD1 | defender against cell death 1 | -0.00638532 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.00636349 |
| KRT6B | keratin 6B, type II | -0.00634947 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | -0.00633254 |
| INHBB | inhibin, beta B | -0.00632197 |
| ORC1 | origin recognition complex, subunit 1 | -0.00624843 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | -0.006241 |
| PRR16 | proline rich 16 | -0.00622276 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.00617712 |
| LY6H | lymphocyte antigen 6 complex, locus H | -0.00616357 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | -0.00615723 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00613176 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | -0.00610874 |
| CDH13 | cadherin 13 | -0.00607878 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.00603906 |
| GSTT1 | glutathione S-transferase theta 1 | -0.00603067 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -0.00602842 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00602146 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | -0.00600918 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00600484 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.0059725 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00596328 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B | -0.00594614 |
| COG7 | component of oligomeric golgi complex 7 | -0.00594245 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00591261 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0059044 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.00588642 |
| H1-0 | H1.0 linker histone | -0.00585622 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | -0.00585336 |
| SC5D | sterol-C5-desaturase | -0.00584469 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | -0.00584171 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00583854 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.00582733 |
| TPBG | trophoblast glycoprotein | -0.00581261 |
| FOLR1 | folate receptor 1 (adult) | -0.00580754 |
| IFI30 | interferon, gamma-inducible protein 30 | -0.00580186 |
| KRT5 | keratin 5, type II | -0.00579003 |
| CDC20 | cell division cycle 20 | -0.00578482 |
| OAZ1 | ornithine decarboxylase antizyme 1 | -0.00573154 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | -0.005729 |
| PITX2 | paired-like homeodomain 2 | -0.00572727 |
| PCDH8 | protocadherin 8 | -0.00570753 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00568074 |
| THAP9-AS1 | THAP9 antisense RNA 1 | -0.0056403 |
| SFTPB | surfactant protein B | -0.00561169 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00559847 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | -0.00558644 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0055794 |
| PRMT5 | protein arginine methyltransferase 5 | -0.00556726 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00556649 |
| EZR | ezrin | -0.00555651 |
| TXNDC9 | thioredoxin domain containing 9 | -0.0055498 |
| PLXNA2 | plexin A2 | -0.00554559 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.00552867 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 | -0.00552228 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | -0.00550545 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00550019 |
| ACTB | actin, beta | -0.00549945 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.00549357 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 | -0.00548991 |
| PXDN | peroxidasin | -0.00548651 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0054742 |
| WBP4 | WW domain binding protein 4 | -0.00547182 |
| GRB14 | growth factor receptor-bound protein 14 | -0.005464 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.00546275 |
| ACADL | acyl-CoA dehydrogenase, long chain | -0.00544348 |
| RYR1 | ryanodine receptor 1 (skeletal) | -0.00544095 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | -0.00543388 |
| TEAD4 | TEA domain family member 4 | -0.00541192 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A | -0.00540121 |
| CRLF1 | cytokine receptor-like factor 1 | -0.00540118 |
| SLC13A1 | solute carrier family 13 (sodium/sulfate symporter), member 1 | -0.00539482 |
| ESM1 | endothelial cell-specific molecule 1 | -0.00537385 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.00535189 |
| ACTA1 | actin, alpha 1, skeletal muscle | -0.00534814 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | -0.00533868 |
| VPREB1 | pre-B lymphocyte 1 | -0.00533529 |
| LRP2 | low density lipoprotein receptor-related protein 2 | -0.00532445 |
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble | -0.00531272 |
| S100A2 | S100 calcium binding protein A2 | -0.00530885 |
| KRT6A | keratin 6A, type II | -0.00529587 |
| TRIM5 | tripartite motif containing 5 | -0.00528031 |
| C14ORF105 | chromosome 14 open reading frame 105 | -0.0052526 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.00524857 |
| ENO1 | enolase 1, (alpha) | -0.00523564 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.00522652 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.00522309 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -0.00521892 |
| CAPNS1 | calpain, small subunit 1 | -0.00520821 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | -0.00520751 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | -0.00519407 |
| NXN | nucleoredoxin | -0.0051938 |
| PCBP2 | poly(rC) binding protein 2 | -0.00518444 |
| MEF2C | myocyte enhancer factor 2C | -0.00517136 |
| NMU | neuromedin U | -0.00517094 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F | -0.00515401 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.00514643 |
| RETREG1 | reticulophagy regulator 1 | -0.00514238 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00512743 |
| PKP2 | plakophilin 2 | -0.00512633 |
| RTN4 | reticulon 4 | -0.00512097 |
| CLEC2D | C-type lectin domain family 2, member D | -0.00511583 |
| HMOX2 | heme oxygenase 2 | -0.0050907 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00508764 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.0050807 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.00507875 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00506358 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00505761 |
| ANXA5 | annexin A5 | -0.00504483 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.00504216 |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A | -0.00503208 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00501637 |
| LOX | lysyl oxidase | -0.00501462 |
| CCNC | cyclin C | -0.00499789 |
| CALML4 | calmodulin-like 4 | -0.00499255 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00497459 |
| GANAB | glucosidase, alpha; neutral AB | -0.00497268 |
| CD200 | CD200 molecule | -0.00496519 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like | -0.00494368 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | -0.00494365 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.00493694 |
| TMEM41B | transmembrane protein 41B | -0.00493264 |
| MSLN | mesothelin | -0.0049185 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -0.0049054 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00490004 |
| HSPA8 | heat shock 70kDa protein 8 | -0.00489335 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | -0.00488765 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | -0.00488671 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | -0.00488209 |
| RAPGEF4 | Rap guanine nucleotide exchange factor (GEF) 4 | -0.00487183 |
| KIAA1644 | KIAA1644 | -0.00484978 |
| MRPL19 | mitochondrial ribosomal protein L19 | -0.00484475 |
| NDNF | neuron-derived neurotrophic factor | -0.00483124 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | -0.00482873 |
| CTSZ | cathepsin Z | -0.00482373 |
| GPX1 | glutathione peroxidase 1 | -0.00481948 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00481703 |
| CNN2 | calponin 2 | -0.00481677 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00480962 |
| CYB561 | cytochrome b561 | -0.00480407 |
| NDRG1 | N-myc downstream regulated 1 | -0.00480386 |
| PFKP | phosphofructokinase, platelet | -0.0047977 |
| LIG4 | ligase IV, DNA, ATP-dependent | -0.00479387 |
| PRPF31 | pre-mRNA processing factor 31 | -0.00478995 |
| SSR4 | signal sequence receptor, delta | -0.00478606 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | -0.00476506 |
| NRBF2 | nuclear receptor binding factor 2 | -0.0047551 |
| ZNF395 | zinc finger protein 395 | -0.00474562 |
| STK17A | serine/threonine kinase 17a | -0.00473892 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.00473403 |
| ODC1 | ornithine decarboxylase 1 | -0.00471898 |
| ATP6V0D1 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | -0.00471868 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00471189 |
| TPP1 | tripeptidyl peptidase I | -0.00467621 |
| USP11 | ubiquitin specific peptidase 11 | -0.00466501 |
| IL21R | interleukin 21 receptor | -0.0046574 |
| TLK2 | tousled-like kinase 2 | -0.00465739 |
| NHP2 | NHP2 ribonucleoprotein | -0.00464178 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | -0.00463579 |
| TPI1 | triosephosphate isomerase 1 | -0.00461565 |
| BDNF | brain-derived neurotrophic factor | -0.00461055 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 | -0.00460848 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.0046084 |
| PKM | pyruvate kinase, muscle | -0.00460629 |
| ZNF675 | zinc finger protein 675 | -0.00460358 |
| DSC2 | desmocollin 2 | -0.00459311 |
| MRPS7 | mitochondrial ribosomal protein S7 | -0.00458655 |
| GORASP2 | golgi reassembly stacking protein 2, 55kDa | -0.00458016 |
| RIT1 | Ras-like without CAAX 1 | -0.00457855 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | -0.00457686 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.00457395 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.00456483 |
| L1TD1 | LINE-1 type transposase domain containing 1 | -0.00456294 |
| EGR1 | early growth response 1 | -0.0045622 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.00456065 |
| PUF60 | poly-U binding splicing factor 60KDa | -0.00455996 |
| SNX5 | sorting nexin 5 | -0.00455638 |
| GSAP | gamma-secretase activating protein | -0.0045301 |
| PPT1 | palmitoyl-protein thioesterase 1 | -0.00452856 |
| SPIN1 | spindlin 1 | -0.00452661 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.0045259 |
| CLIC3 | chloride intracellular channel 3 | -0.00452415 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00451916 |
| YIPF5 | Yip1 domain family, member 5 | -0.00451085 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) | -0.00450666 |
| UGT8 | UDP glycosyltransferase 8 | -0.00449883 |
| SYNJ2 | synaptojanin 2 | -0.0044982 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00449069 |
| SEC13 | SEC13 homolog (S. cerevisiae) | -0.00448806 |
| SLC22A11 | solute carrier family 22 (organic anion/urate transporter), member 11 | -0.0044724 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00447071 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | -0.00446594 |
| COMP | cartilage oligomeric matrix protein | -0.00445799 |
| FASTKD1 | FAST kinase domains 1 | -0.00445115 |
| PMM2 | phosphomannomutase 2 | -0.00444663 |
