RAF1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description Raf-1 proto-oncogene, serine/threonine kinase|This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5894)
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Genes

433 genes differentially expressed following the RAF1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ARHGAP20 Rho GTPase activating protein 20 3.18964
KHDC3L KH domain containing 3-like, subcortical maternal complex member 3.18964
GPR183 G protein-coupled receptor 183 3.18964
GNAT3 guanine nucleotide binding protein, alpha transducing 3 3.18964
AMER2 APC membrane recruitment protein 2 3.18964
HSPA1L heat shock 70kDa protein 1-like 3.18964
C6ORF118 chromosome 6 open reading frame 118 3.18964
THBD thrombomodulin 3.18964
TUBB8 tubulin, beta 8 class VIII 3.18964
SP140 SP140 nuclear body protein 3.18964
MRAP melanocortin 2 receptor accessory protein 3.18964
C5ORF58 chromosome 5 open reading frame 58 3.18964
DES desmin 3.18964
GOLGA6A golgin A6 family, member A 3.18964
FOXA2 forkhead box A2 3.18964
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 3.18964
MUC6 mucin 6, oligomeric mucus/gel-forming 3.18964
VTN vitronectin 3.18964
RAB36 RAB36, member RAS oncogene family 3.18964
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 3.18964
FRMPD1 FERM and PDZ domain containing 1 3.18964
CATSPERZ catsper channel auxiliary subunit zeta 3.18964
IRX3 iroquois homeobox 3 3.18964
IKZF3 IKAROS family zinc finger 3 (Aiolos) 3.18964
CPLX1 complexin 1 3.18964
HES2 hes family bHLH transcription factor 2 3.18964
DMRT1 doublesex and mab-3 related transcription factor 1 3.18964
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 3.18964
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 3.17238
IL22RA1 interleukin 22 receptor, alpha 1 3.17238
KRT20 keratin 20, type I 3.17238
OR10A6 olfactory receptor, family 10, subfamily A, member 6 (gene/pseudogene) 3.17238
GRM2 glutamate receptor, metabotropic 2 3.17238
SERTM1 serine-rich and transmembrane domain containing 1 3.17238
PDZD9 PDZ domain containing 9 3.17238
LRRC56 leucine rich repeat containing 56 3.17238
CX3CL1 chemokine (C-X3-C motif) ligand 1 3.17238
TM4SF1 transmembrane 4 L six family member 1 3.17238
RNASE9 ribonuclease, RNase A family, 9 (non-active) 3.17238
FGF7 fibroblast growth factor 7 3.17238
TSGA13 testis specific, 13 3.17238
PDIA2 protein disulfide isomerase family A, member 2 3.17238
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 3.17238
FGL1 fibrinogen-like 1 3.17238
TRIM17 tripartite motif containing 17 3.17238
MBLAC1 metallo-beta-lactamase domain containing 1 3.17238
HEATR9 HEAT repeat containing 9 3.17238
FOXR1 forkhead box R1 3.17238
TMEM217 transmembrane protein 217 3.17238
MAS1 MAS1 proto-oncogene, G protein-coupled receptor 3.17238
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 3.17238
CPB1 carboxypeptidase B1 (tissue) 3.17238
ACVRL1 activin A receptor type II-like 1 3.17238
OCSTAMP osteoclast stimulatory transmembrane protein 3.17238
CX3CR1 chemokine (C-X3-C motif) receptor 1 3.17238
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 3.17238
CCDC38 coiled-coil domain containing 38 3.17238
SHE Src homology 2 domain containing E 3.17238
C1ORF146 chromosome 1 open reading frame 146 3.17238
IL2RG interleukin 2 receptor, gamma 3.17238
FAM90A1 family with sequence similarity 90, member A1 3.17238
XCL1 chemokine (C motif) ligand 1 3.17238
NFAM1 NFAT activating protein with ITAM motif 1 3.17238
TUBB1 tubulin, beta 1 class VI 3.17238
MED19 mediator complex subunit 19 3.17238
TAS2R1 taste receptor, type 2, member 1 3.17238
CSNK2A3 casein kinase 2, alpha 3 polypeptide 3.17238
MFAP5 microfibrillar associated protein 5 3.17238
GRP gastrin-releasing peptide 3.17238
GUCY2F guanylate cyclase 2F, retinal 3.17238
LRRC63 leucine rich repeat containing 63 3.17238
COLEC10 collectin sub-family member 10 (C-type lectin) 3.17238
CATSPERT catsper channel auxiliary subunit tau 3.17238
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase 3.17238
KRT81 keratin 81, type II 3.17238
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 3.17238
XKR3 XK, Kell blood group complex subunit-related family, member 3 3.17238
SELL selectin L 3.17238
FOXD4L5 forkhead box D4-like 5 3.17238
BEST3 bestrophin 3 3.17238
COX8C cytochrome c oxidase subunit VIIIC 3.17238
GDF9 growth differentiation factor 9 3.17238
GPR83 G protein-coupled receptor 83 3.17238
ZAR1L zygote arrest 1-like 3.17238
FAM131C family with sequence similarity 131, member C 3.17238
RD3 retinal degeneration 3 3.17238
AVPR1A arginine vasopressin receptor 1A 3.17238
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 3.17238
FAM240C family with sequence similarity 240 member C 3.17238
LIPT2-AS1 LIPT2 antisense RNA 1 3.17238
NOTCH2NLB notch 2 N-terminal like B 3.17238
SPMIP3 sperm microtubule inner protein 3 3.17238
C17ORF113 chromosome 17 open reading frame 113 3.17238
LY6L lymphocyte antigen 6 family member L 3.17238
TUBB8B tubulin beta 8B 3.17238
H4C13 H4 clustered histone 13 3.17238
SLC49A3 solute carrier family 49 member 3 3.17238
H3-5 H3.5 histone 3.17238
SEPTIN14 septin 14 3.17238
HAO2 hydroxyacid oxidase 2 (long chain) 3.17238
ARHGAP15 Rho GTPase activating protein 15 3.17238
VCX3B variable charge, X-linked 3B 3.17238
SBSN suprabasin 3.17238
ACOT1 acyl-CoA thioesterase 1 3.17238
RLBP1 retinaldehyde binding protein 1 3.17238
OR2A5 olfactory receptor, family 2, subfamily A, member 5 3.17238
HINT3 histidine triad nucleotide binding protein 3 3.17238
HHEX hematopoietically expressed homeobox 3.17238
SYCP1 synaptonemal complex protein 1 3.17238
COL19A1 collagen, type XIX, alpha 1 3.17238
LOX lysyl oxidase 3.17238
SIX3 SIX homeobox 3 3.17238
TSHB thyroid stimulating hormone, beta 3.17238
SELPLG selectin P ligand 3.17238
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 3.17238
SECTM1 secreted and transmembrane 1 3.17238
FOXD1 forkhead box D1 3.17238
KLHL33 kelch-like family member 33 3.17238
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 3.17238
TMEM179 transmembrane protein 179 3.17238
TBX3 T-box 3 3.17238
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 3.17238
SLC45A2 solute carrier family 45, member 2 3.17238
SCIMP SLP adaptor and CSK interacting membrane protein 3.17238
ADGRG1 adhesion G protein-coupled receptor G1 3.17238
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 3.17238
IL6 interleukin 6 3.17238
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4 3.17238
AKR1D1 aldo-keto reductase family 1, member D1 3.17238
ZBTB16 zinc finger and BTB domain containing 16 3.17238
WDR87 WD repeat domain 87 3.17238
LZIC leucine zipper and CTNNBIP1 domain containing 3.17238
CABP7 calcium binding protein 7 3.17238
PCDHGB1 protocadherin gamma subfamily B, 1 3.17238
SPTBN5 spectrin, beta, non-erythrocytic 5 3.17238
NPPA natriuretic peptide A 3.17238
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 3.17238
TMEM132D transmembrane protein 132D 3.17238
TEX11 testis expressed 11 3.17238
TTC16 tetratricopeptide repeat domain 16 3.17238
FBXO40 F-box protein 40 3.17238
LRRC32 leucine rich repeat containing 32 3.17238
PMP2 peripheral myelin protein 2 3.17238
CFAP61 cilia and flagella associated protein 61 3.17238
SPEF1 sperm flagellar 1 3.17238
TCF21 transcription factor 21 3.17238
TSPAN32 tetraspanin 32 3.17238
ZMYND10 zinc finger, MYND-type containing 10 3.17238
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 3.17238
ITGA10 integrin, alpha 10 3.17238
PHOSPHO1 phosphatase, orphan 1 3.17238
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 3.17238
RGS11 regulator of G-protein signaling 11 3.17238
SUPT20HL1 suppressor of Ty 20 homolog (S. cerevisiae)-like 1 3.17238
NXNL1 nucleoredoxin-like 1 3.17238
TMEM139 transmembrane protein 139 3.17238
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 3.17238
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 3.17238
ERICH6B glutamate-rich 6B 3.17238
TPSB2 tryptase beta 2 (gene/pseudogene) 3.17238
AKNAD1 AKNA domain containing 1 3.17238
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 3.17238
C22ORF42 chromosome 22 open reading frame 42 3.17238
FAM209A family with sequence similarity 209, member A 3.17238
COX7B2 cytochrome c oxidase subunit VIIb2 3.17238
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 3.17238
C8ORF89 chromosome 8 open reading frame 89 3.17238
RAB40AL RAB40A, member RAS oncogene family-like 3.17238
CST7 cystatin F (leukocystatin) 3.17238
TESPA1 thymocyte expressed, positive selection associated 1 3.17238
SIAH3 siah E3 ubiquitin protein ligase family member 3 3.17238
ZNRF4 zinc and ring finger 4 3.17238
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 3.17238
TNR tenascin R 3.17238
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 3.17238
NPBWR1 neuropeptides B/W receptor 1 3.17238
CRTAM cytotoxic and regulatory T cell molecule 3.17238
IL37 interleukin 37 3.17238
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae) 3.17238
ANGPTL3 angiopoietin-like 3 3.17238
MYADML2 myeloid-associated differentiation marker-like 2 3.17238
CASR calcium-sensing receptor 3.17238
CCNO cyclin O 3.17238
DRD3 dopamine receptor D3 3.17238
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 3.17238
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 3.17238
IL33 interleukin 33 3.17238
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 3.17238
RAD9B RAD9 homolog B (S. pombe) 3.17238
GOLGA8N golgin A8 family, member N 3.17238
ANXA2R annexin A2 receptor 3.17238
CD38 CD38 molecule 3.17238
TMEM184A transmembrane protein 184A 3.17238
GOLGA8K golgin A8 family, member K 3.17238
MEPE matrix extracellular phosphoglycoprotein 3.17238
CLEC2A C-type lectin domain family 2, member A 3.17238
LOXL4 lysyl oxidase-like 4 3.17238
LY6G5C lymphocyte antigen 6 complex, locus G5C 3.17238
MMP1 matrix metallopeptidase 1 3.17238
SCNN1B sodium channel, non voltage gated 1 beta subunit 3.17238
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 3.17238
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 3.17238
PRSS33 protease, serine, 33 3.17238
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 3.17238
BATF2 basic leucine zipper transcription factor, ATF-like 2 3.17238
NT5DC4 5'-nucleotidase domain containing 4 3.17238
HHIPL2 HHIP-like 2 3.17238
GPR68 G protein-coupled receptor 68 3.17238
LRRC74A leucine rich repeat containing 74A 3.17238
OR56B4 olfactory receptor, family 56, subfamily B, member 4 3.17238
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial 3.14284
MMP16 matrix metallopeptidase 16 (membrane-inserted) 3.13249
FBXO46 F-box protein 46 3.09319
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 3.03904
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 3.03904
RNF222 ring finger protein 222 2.99856
ZNF521 zinc finger protein 521 2.96022
TMX3 thioredoxin-related transmembrane protein 3 2.9101
CNMD chondromodulin 2.8903
MYO15A myosin XVA 2.88636
MYO1E myosin IE 2.85684
SCUBE2 signal peptide, CUB domain, EGF-like 2 2.82607
SSH2 slingshot protein phosphatase 2 2.79003
COXFA4 cytochrome c oxidase associated subunit FA4 2.77975
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 2.57606
H3-3A H3.3 histone A 2.53437
FANCF Fanconi anemia, complementation group F 2.51848
FOXK2 forkhead box K2 2.49315
CITED4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 2.46715
PCDHA6 protocadherin alpha 6 2.46514
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit 2.43446
RBM38 RNA binding motif protein 38 2.42315
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 2.42249
ZNF8 zinc finger protein 8 2.41717
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 2.40761
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 2.40297
NOSIP nitric oxide synthase interacting protein 2.37464
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 2.37096
COMMD1 copper metabolism (Murr1) domain containing 1 2.35167
JMJD6 jumonji domain containing 6 2.33791
OTUD3 OTU deubiquitinase 3 2.32614
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 2.31668
KIAA2013 KIAA2013 2.26217
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 2.26203
UQCRC1 ubiquinol-cytochrome c reductase core protein I 2.25999
CACUL1 CDK2-associated, cullin domain 1 2.25447
COX5B cytochrome c oxidase subunit Vb 2.23824
SVBP small vasohibin binding protein 2.22575
ZNF157 zinc finger protein 157 2.21617
KLF10 Kruppel-like factor 10 2.215
MARCHF6 membrane associated ring-CH-type finger 6 2.21179
RNF181 ring finger protein 181 2.1904
FHL1 four and a half LIM domains 1 2.18279
WDR77 WD repeat domain 77 2.13103
TUBA1B tubulin, alpha 1b 2.13076
IFNGR1 interferon gamma receptor 1 2.13076
RFK riboflavin kinase 2.12644
PRDX1 peroxiredoxin 1 2.12635
NOX4 NADPH oxidase 4 2.12601
NUP54 nucleoporin 54kDa 2.12601
NUAK1 NUAK family, SNF1-like kinase, 1 2.1198
NUP188 nucleoporin 188kDa 2.11974
SSB Sjogren syndrome antigen B (autoantigen La) 2.11974
CASP8AP2 caspase 8 associated protein 2 2.11974
TM9SF2 transmembrane 9 superfamily member 2 2.11765
ACAD10 acyl-CoA dehydrogenase family, member 10 2.11508
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 2.11508
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 2.11411
TSPAN3 tetraspanin 3 2.11324
TSLIG3C tRNA splicing ligase complex subunit 3C 2.10188
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C 2.10188
GEMIN7 gem (nuclear organelle) associated protein 7 2.096
LONRF1 LON peptidase N-terminal domain and ring finger 1 2.09446
COPG1 coatomer protein complex, subunit gamma 1 2.08682
ARMC2 armadillo repeat containing 2 2.07228
SYNGR1 synaptogyrin 1 2.06394
OAZ1 ornithine decarboxylase antizyme 1 2.05878
TUBB3 tubulin, beta 3 class III 2.05616
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G 2.05307
MRPL38 mitochondrial ribosomal protein L38 2.05275
VPS33B vacuolar protein sorting 33 homolog B (yeast) 2.04786
PEX12 peroxisomal biogenesis factor 12 2.04424
CBX8 chromobox homolog 8 2.04424
POU5F2 POU domain class 5, transcription factor 2 2.04424
PCDHA5 protocadherin alpha 5 2.04424
DNM3 dynamin 3 2.04424
CDH12 cadherin 12, type 2 (N-cadherin 2) 2.04424
NGFR nerve growth factor receptor 2.04424
PABPC1L2B poly(A) binding protein, cytoplasmic 1-like 2B 2.04424
FZD9 frizzled class receptor 9 2.04424
NGF nerve growth factor (beta polypeptide) 2.04424
C4ORF51 chromosome 4 open reading frame 51 2.04424
MRPS31 mitochondrial ribosomal protein S31 2.04319
METTL3 methyltransferase like 3 2.04057
XKR9 XK, Kell blood group complex subunit-related family, member 9 2.03045
NIBAN1 niban apoptosis regulator 1 2.02671
PPME1 protein phosphatase methylesterase 1 2.02671
HSPE1 heat shock 10kDa protein 1 2.01857
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.01586
EFR3B EFR3 homolog B (S. cerevisiae) 2.01361
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 2.01129

decreased expression

Symbol Name Standardized Value
BTN2A2 butyrophilin, subfamily 2, member A2 -3.18964
RSPH1 radial spoke head 1 homolog (Chlamydomonas) -3.18964
NCR1 natural cytotoxicity triggering receptor 1 -3.18964
SYCE3 synaptonemal complex central element protein 3 -3.17238
RPEL1 ribulose-5-phosphate-3-epimerase-like 1 -3.17238
KIF12 kinesin family member 12 -3.17238
RGPD5 RANBP2-like and GRIP domain containing 5 -3.17238
NCKAP5 NCK-associated protein 5 -3.17238
C10ORF90 chromosome 10 open reading frame 90 -3.17238
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) -3.17238
ARMCX6 armadillo repeat containing, X-linked 6 -3.17238
ALOX15B arachidonate 15-lipoxygenase, type B -3.17238
PTGDR prostaglandin D2 receptor (DP) -3.17238
CPZ carboxypeptidase Z -3.17238
TMEM132E transmembrane protein 132E -3.17238
CHL1 cell adhesion molecule L1-like -3.17238
OXTR oxytocin receptor -3.17238
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 -3.17238
LOC122539214 Zinc finger protein LOC122539214 -3.17238
POLR1H RNA polymerase I subunit H -3.17238
ELFN2 extracellular leucine-rich repeat and fibronectin type III domain containing 2 -3.17238
PRDM6 PR domain containing 6 -3.17238
BEST2 bestrophin 2 -3.17238
OR2A25 olfactory receptor, family 2, subfamily A, member 25 -3.17238
LDHD lactate dehydrogenase D -3.17238
UPK3B uroplakin 3B -3.17238
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 -3.17238
PLXDC2 plexin domain containing 2 -3.17238
RASA4B RAS p21 protein activator 4B -3.17238
C19ORF38 chromosome 19 open reading frame 38 -3.17238
ZNF230 zinc finger protein 230 -3.17238
IFT70B intraflagellar transport 70B -3.17238
UFSP1 UFM1-specific peptidase 1 (non-functional) -3.17238
GLB1L2 galactosidase, beta 1-like 2 -3.17238
RAB40A RAB40A, member RAS oncogene family -3.17238
VSTM1 V-set and transmembrane domain containing 1 -3.17238
TMEM31 transmembrane protein 31 -3.17238
KBTBD8 kelch repeat and BTB (POZ) domain containing 8 -3.17238
CXCR4 chemokine (C-X-C motif) receptor 4 -3.17238
ACSBG2 acyl-CoA synthetase bubblegum family member 2 -3.17238
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) -3.17238
FBXW11 F-box and WD repeat domain containing 11 -3.13069
HASPIN histone H3 associated protein kinase -3.12929
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A -3.1193
CATSPERQ catsper channel auxiliary subunit theta -3.1193
USP3 ubiquitin specific peptidase 3 -3.09714
TOMM34 translocase of outer mitochondrial membrane 34 -3.07144
ZBTB7B zinc finger and BTB domain containing 7B -2.85869
KIF7 kinesin family member 7 -2.78342
PNKP polynucleotide kinase 3'-phosphatase -2.77418
NHSL2 NHS-like 2 -2.76794
SUN2 Sad1 and UNC84 domain containing 2 -2.72066
PCDH11X protocadherin 11 X-linked -2.72066
ZNF101 zinc finger protein 101 -2.69649
RPS19 ribosomal protein S19 -2.66904
NBAS neuroblastoma amplified sequence -2.6643
CCNE2 cyclin E2 -2.6643
CDCA4 cell division cycle associated 4 -2.65742
IRS4 insulin receptor substrate 4 -2.6503
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae) -2.61547
UBXN2A UBX domain protein 2A -2.56134
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -2.5234
TUBA8 tubulin, alpha 8 -2.51952
TFE3 transcription factor binding to IGHM enhancer 3 -2.51203
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.48583
GPR75-ASB3 GPR75-ASB3 readthrough -2.47335
SUSD5 sushi domain containing 5 -2.46925
QKI QKI, KH domain containing, RNA binding -2.42722
LAPTM4B lysosomal protein transmembrane 4 beta -2.41893
DCK deoxycytidine kinase -2.37952
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 -2.37768
NUCB2 nucleobindin 2 -2.36223
PGLYRP1 peptidoglycan recognition protein 1 -2.35167
PCDHB16 protocadherin beta 16 -2.35167
APLN apelin -2.35167
AGTRAP angiotensin II receptor-associated protein -2.34684
GABPB2 GA binding protein transcription factor, beta subunit 2 -2.31769
POT1 protection of telomeres 1 -2.30387
LNX2 ligand of numb-protein X 2 -2.28254
AK7 adenylate kinase 7 -2.27585
CDK18 cyclin-dependent kinase 18 -2.27585
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -2.26935
UBE2F ubiquitin-conjugating enzyme E2F (putative) -2.26762
FAM222B family with sequence similarity 222, member B -2.26602
MYH14 myosin, heavy chain 14, non-muscle -2.26031
SCD5 stearoyl-CoA desaturase 5 -2.23974
TXNIP thioredoxin interacting protein -2.23824
SLC16A6 solute carrier family 16, member 6 -2.23824
TMEM132B transmembrane protein 132B -2.23824
BEAN1 brain expressed, associated with NEDD4, 1 -2.23824
DENND5B DENN/MADD domain containing 5B -2.22692
COL6A1 collagen, type VI, alpha 1 -2.215
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -2.21398
ITPKB inositol-trisphosphate 3-kinase B -2.20237
THBS4 thrombospondin 4 -2.1904
C11ORF42 chromosome 11 open reading frame 42 -2.1904
PIWIL2 piwi-like RNA-mediated gene silencing 2 -2.1904
PRDM1 PR domain containing 1, with ZNF domain -2.1904
PKLR pyruvate kinase, liver and RBC -2.1904
KIFC2 kinesin family member C2 -2.1904
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 -2.1904
TMED6 transmembrane emp24 protein transport domain containing 6 -2.1904
OPRL1 opiate receptor-like 1 -2.1904
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -2.1904
OCA2 oculocutaneous albinism II -2.1904
ATP5MC2 ATP synthase membrane subunit c locus 2 -2.19007
HLA-E major histocompatibility complex, class I, E -2.16121
TFPI2 tissue factor pathway inhibitor 2 -2.15626
ALPK3 alpha-kinase 3 -2.15621
PTPRG protein tyrosine phosphatase, receptor type, G -2.1489
MYH10 myosin, heavy chain 10, non-muscle -2.1489
PAPPA2 pappalysin 2 -2.13839
LAMC1 laminin, gamma 1 (formerly LAMB2) -2.13103
UQCC4 ubiquinol-cytochrome c reductase complex assembly factor 4 -2.12644
RNF175 ring finger protein 175 -2.1253
NTNG2 netrin G2 -2.11974
SPATS2L spermatogenesis associated, serine-rich 2-like -2.11491
DBN1 drebrin 1 -2.10182
DHX37 DEAH (Asp-Glu-Ala-His) box polypeptide 37 -2.09817
FASTK Fas-activated serine/threonine kinase -2.09817
MPHOSPH6 M-phase phosphoprotein 6 -2.08015
MGMT O-6-methylguanine-DNA methyltransferase -2.07395
GSE1 Gse1 coiled-coil protein -2.06394
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 -2.06381
BEND5 BEN domain containing 5 -2.06367
BEX5 brain expressed, X-linked 5 -2.06103
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 -2.05447
ZSCAN21 zinc finger and SCAN domain containing 21 -2.04439
RASL11B RAS-like, family 11, member B -2.03045
DPEP3 dipeptidase 3 -2.02143
EXOC4 exocyst complex component 4 -2.02143
RNF26 ring finger protein 26 -2.01722