RAF1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description Raf-1 proto-oncogene, serine/threonine kinase|This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5894)
External Link http://www.ncbi.nlm.nih.gov/gene/5894
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Genes

662 interacting proteins for RAF1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
AASS aminoadipate-semialdehyde synthase
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ABLIM1 actin binding LIM protein 1
ACACA acetyl-CoA carboxylase alpha
ACOT8 acyl-CoA thioesterase 8
ACTL6A actin-like 6A
ADCY6 adenylate cyclase 6
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AGTR1 angiotensin II receptor, type 1
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AIP aryl hydrocarbon receptor interacting protein
AKAP8 A kinase (PRKA) anchor protein 8
AKAP8L A kinase (PRKA) anchor protein 8-like
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALOX15 arachidonate 15-lipoxygenase
AMPD2 adenosine monophosphate deaminase 2
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
APAF1 apoptotic peptidase activating factor 1
AR androgen receptor
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARF4 ADP-ribosylation factor 4
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARL1 ADP-ribosylation factor-like 1
ARRB2 arrestin, beta 2
ASS1 argininosuccinate synthase 1
ATAD3A ATPase family, AAA domain containing 3A
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
AURKB aurora kinase B
BAD BCL2-associated agonist of cell death
BAG1 BCL2-associated athanogene
BAG2 BCL2-associated athanogene 2
BAIAP2 BAI1-associated protein 2
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL6 B-cell CLL/lymphoma 6
BCR breakpoint cluster region
BIN1 bridging integrator 1
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BIRC7 baculoviral IAP repeat containing 7
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRAP BRCA1 associated protein
C1QBP complement component 1, q subcomponent binding protein
CACYBP calcyclin binding protein
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALU calumenin
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC6 coiled-coil domain containing 6
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT3 chaperonin containing TCP1, subunit 3 (gamma)
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDC37 cell division cycle 37
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDK1 cyclin-dependent kinase 1
CDK11A cyclin-dependent kinase 11A
CDK11B cyclin-dependent kinase 11B
CDK16 cyclin-dependent kinase 16
CDK17 cyclin-dependent kinase 17
CDK18 cyclin-dependent kinase 18
CDK20 cyclin-dependent kinase 20
CDK4 cyclin-dependent kinase 4
CDK9 cyclin-dependent kinase 9
CEP170 centrosomal protein 170kDa
CEP170B centrosomal protein 170B
CEP250 centrosomal protein 250kDa
CEPT1 choline/ethanolamine phosphotransferase 1
CFLAR CASP8 and FADD-like apoptosis regulator
CGN cingulin
CHD4 chromodomain helicase DNA binding protein 4
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
CHUK conserved helix-loop-helix ubiquitous kinase
CLASP1 cytoplasmic linker associated protein 1
CLASP2 cytoplasmic linker associated protein 2
CLK3 CDC-like kinase 3
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
COPG1 coatomer protein complex, subunit gamma 1
COPG2 coatomer protein complex, subunit gamma 2
COPS3 COP9 signalosome subunit 3
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRTC1 CREB regulated transcription coactivator 1
CRTC2 CREB regulated transcription coactivator 2
CRTC3 CREB regulated transcription coactivator 3
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSNK1A1 casein kinase 1, alpha 1
CTSB cathepsin B
CTTN cortactin
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYLD cylindromatosis (turban tumor syndrome)
CYR61 cysteine-rich, angiogenic inducer, 61
DCAF7 DDB1 and CUL4 associated factor 7
DDR1 discoidin domain receptor tyrosine kinase 1
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND1A DENN/MADD domain containing 1A
DENND4A DENN/MADD domain containing 4A
DENND4C DENN/MADD domain containing 4C
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DMPK dystrophia myotonica-protein kinase
DMTN dematin actin binding protein
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
DOCK11 dedicator of cytokinesis 11
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK2 docking protein 2, 56kDa
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
EDC3 enhancer of mRNA decapping 3
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1G eukaryotic translation elongation factor 1 gamma
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFTUD2 elongation factor Tu GTP binding domain containing 2
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3I eukaryotic translation initiation factor 3, subunit I
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4E2 eukaryotic translation initiation factor 4E family member 2
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
EP400 E1A binding protein p400
EPB41L3 erythrocyte membrane protein band 4.1-like 3
ERAS ES cell expressed Ras
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB2IP erbb2 interacting protein
ERCC3 excision repair cross-complementation group 3
ETFA electron-transfer-flavoprotein, alpha polypeptide
EXO1 exonuclease 1
FAM27E3 family with sequence similarity 27, member E3
FAM53C family with sequence similarity 53, member C
FAM96B family with sequence similarity 96, member B
FANCD2 Fanconi anemia, complementation group D2
FANCI Fanconi anemia, complementation group I
FASN fatty acid synthase
FBL fibrillarin
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FBXW8 F-box and WD repeat domain containing 8
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FER fer (fps/fes related) tyrosine kinase
FKBP4 FK506 binding protein 4, 59kDa
FKBP5 FK506 binding protein 5
FKBPL FK506 binding protein like
FOXO3 forkhead box O3
FYN FYN proto-oncogene, Src family tyrosine kinase
GANAB glucosidase, alpha; neutral AB
GAPVD1 GTPase activating protein and VPS9 domains 1
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCDH glutaryl-CoA dehydrogenase
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GIGYF1 GRB10 interacting GYF protein 1
GIGYF2 GRB10 interacting GYF protein 2
GLMN glomulin, FKBP associated protein
GLUD1 glutamate dehydrogenase 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPRASP2 G protein-coupled receptor associated sorting protein 2
GRB10 growth factor receptor-bound protein 10
GRIP1 glutamate receptor interacting protein 1
GSG2 germ cell associated 2 (haspin)
GTF2I general transcription factor IIi
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HAUS5 HAUS augmin-like complex, subunit 5
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HELLS helicase, lymphoid-specific
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HIPK4 homeodomain interacting protein kinase 4
HIST1H2BL histone cluster 1, H2bl
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPM heterogeneous nuclear ribonucleoprotein M
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1B heat shock 70kDa protein 1B
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL2RB interleukin 2 receptor, beta
ILK integrin-linked kinase
ILVBL ilvB (bacterial acetolactate synthase)-like
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INPP5F inositol polyphosphate-5-phosphatase F
INSR insulin receptor
INTS10 integrator complex subunit 10
IPO13 importin 13
IPO4 importin 4
IPO7 importin 7
IPO9 importin 9
IQGAP2 IQ motif containing GTPase activating protein 2
IQGAP3 IQ motif containing GTPase activating protein 3
IRAK1 interleukin-1 receptor-associated kinase 1
IRS2 insulin receptor substrate 2
IRS4 insulin receptor substrate 4
JAK1 Janus kinase 1
JAK2 Janus kinase 2
KIAA0355 KIAA0355
KIAA0930 KIAA0930
KIAA1671 KIAA1671
KIF1B kinesin family member 1B
KIF1C kinesin family member 1C
KIF23 kinesin family member 23
KIF5B kinesin family member 5B
KLC1 kinesin light chain 1
KLC2 kinesin light chain 2
KLC3 kinesin light chain 3
KLC4 kinesin light chain 4
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KPNA4 karyopherin alpha 4 (importin alpha 3)
KPNB1 karyopherin (importin) beta 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT18 keratin 18, type I
KRT19 keratin 19, type I
KRT8 keratin 8, type II
KSR1 kinase suppressor of ras 1
KSR2 kinase suppressor of ras 2
LARP1 La ribonucleoprotein domain family, member 1
LATS1 large tumor suppressor kinase 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LIMA1 LIM domain and actin binding 1
LIMS1 LIM and senescent cell antigen-like domains 1
LIMS2 LIM and senescent cell antigen-like domains 2
LMNA lamin A/C
LMO7 LIM domain 7
LONP1 lon peptidase 1, mitochondrial
LPCAT1 lysophosphatidylcholine acyltransferase 1
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LRPPRC leucine-rich pentatricopeptide repeat containing
LSR lipolysis stimulated lipoprotein receptor
LTK leukocyte receptor tyrosine kinase
LUZP1 leucine zipper protein 1
MAGED1 melanoma antigen family D1
MAGED2 melanoma antigen family D2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPKAP1 mitogen-activated protein kinase associated protein 1
MARK1 MAP/microtubule affinity-regulating kinase 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK3 MAP/microtubule affinity-regulating kinase 3
MARS methionyl-tRNA synthetase
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MAST2 microtubule associated serine/threonine kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MAX MYC associated factor X
MCM7 minichromosome maintenance complex component 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLF1 myeloid leukemia factor 1
MLF2 myeloid leukemia factor 2
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MOGS mannosyl-oligosaccharide glucosidase
MRAS muscle RAS oncogene homolog
MRPS22 mitochondrial ribosomal protein S22
MRPS34 mitochondrial ribosomal protein S34
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MSH6 mutS homolog 6
MTMR12 myotubularin related protein 12
MYBBP1A MYB binding protein (P160) 1a
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO5C myosin VC
MYO9A myosin IXA
MYO9B myosin IXB
NADK NAD kinase
NAV1 neuron navigator 1
NCKAP1 NCK-associated protein 1
NCKIPSD NCK interacting protein with SH3 domain
NDUFA4 NDUFA4, mitochondrial complex associated
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEK9 NIMA-related kinase 9
NELFA negative elongation factor complex member A
NELFB negative elongation factor complex member B
NF1 neurofibromin 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NISCH nischarin
NONO non-POU domain containing, octamer-binding
NOP56 NOP56 ribonucleoprotein
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRF1 nuclear respiratory factor 1
NUCLEOLIN nucleolin multifunctional protein
NUDCD3 NudC domain containing 3
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14
NUP133 nucleoporin 133kDa
NUP153 nucleoporin 153kDa
NUP98 nucleoporin 98kDa
OAT ornithine aminotransferase
OIP5 Opa interacting protein 5
OSBPL3 oxysterol binding protein-like 3
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAQR3 progestin and adipoQ receptor family member III
PARD3 par-3 family cell polarity regulator
PARP8 poly (ADP-ribose) polymerase family, member 8
PARVA parvin, alpha
PARVB parvin, beta
PBK PDZ binding kinase
PCBP1 poly(rC) binding protein 1
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDZD11 PDZ domain containing 11
PEBP1 phosphatidylethanolamine binding protein 1
PEBP4 phosphatidylethanolamine-binding protein 4
PELO pelota homolog (Drosophila)
PEX5L peroxisomal biogenesis factor 5-like
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PFKP phosphofructokinase, platelet
PHB prohibitin
PHKA2 phosphorylase kinase, alpha 2 (liver)
PHLDB2 pleckstrin homology-like domain, family B, member 2
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKM pyruvate kinase, muscle
PKP2 plakophilin 2
PLCG1 phospholipase C, gamma 1
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHA7 pleckstrin homology domain containing, family A member 7
PLK1 polo-like kinase 1
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
PNKD paroxysmal nonkinesigenic dyskinesia
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPID peptidylprolyl isomerase D
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PPP5C protein phosphatase 5, catalytic subunit
PPP6C protein phosphatase 6, catalytic subunit
PPT1 palmitoyl-protein thioesterase 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCG protein kinase C, gamma
PRKCH protein kinase C, eta
PRKCI protein kinase C, iota
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKD2 protein kinase D2
PRKD3 protein kinase D3
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKG1 protein kinase, cGMP-dependent, type I
PRPF6 pre-mRNA processing factor 6
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSME4 proteasome (prosome, macropain) activator subunit 4
PTGES2 prostaglandin E synthase 2
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PUM1 pumilio RNA-binding family member 1
R3HDM1 R3H domain containing 1
R3HDM2 R3H domain containing 2
RAB11B RAB11B, member RAS oncogene family
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RAE1 ribonucleic acid export 1
RALGDS ral guanine nucleotide dissociation stimulator
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RANBP2 RAN binding protein 2
RAP1A RAP1A, member of RAS oncogene family
RAP2A RAP2A, member of RAS oncogene family
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASAL2 RAS protein activator like 2
RASD2 RASD family, member 2
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RB1 retinoblastoma 1
RBBP7 retinoblastoma binding protein 7
RBBP8 retinoblastoma binding protein 8
RBL2 retinoblastoma-like 2
RCAN1 regulator of calcineurin 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RCN2 reticulocalbin 2, EF-hand calcium binding domain
REEP1 receptor accessory protein 1
REEP4 receptor accessory protein 4
RERG RAS-like, estrogen-regulated, growth inhibitor
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RFXANK regulatory factor X-associated ankyrin-containing protein
RHEB Ras homolog enriched in brain
RHOT1 ras homolog family member T1
RHOT2 ras homolog family member T2
RICTOR RPTOR independent companion of MTOR, complex 2
RNGTT RNA guanylyltransferase and 5'-phosphatase
RNH1 ribonuclease/angiogenin inhibitor 1
RPAP3 RNA polymerase II associated protein 3
RPN1 ribophorin I
RPN2 ribophorin II
RPP30 ribonuclease P/MRP 30kDa subunit
RPS2 ribosomal protein S2
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RRAS related RAS viral (r-ras) oncogene homolog
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RSU1 Ras suppressor protein 1
RTKN rhotekin
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SACK1B scaffolding CK1 anchoring protein B
SAMD4A sterile alpha motif domain containing 4A
SAMD4B sterile alpha motif domain containing 4B
SARS seryl-tRNA synthetase
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCNN1D sodium channel, non voltage gated 1 delta subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SCO2 SCO2 cytochrome c oxidase assembly protein
SDF4 stromal cell derived factor 4
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SFN stratifin
SGK1 serum/glucocorticoid regulated kinase 1
SH3KBP1 SH3-domain kinase binding protein 1
SH3PXD2A SH3 and PX domains 2A
SH3RF1 SH3 domain containing ring finger 1
SH3RF3 SH3 domain containing ring finger 3
SHKBP1 SH3KBP1 binding protein 1
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SHROOM2 shroom family member 2
SHROOM3 shroom family member 3
SIPA1L2 signal-induced proliferation-associated 1 like 2
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SKP1 S-phase kinase-associated protein 1
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLIT2 slit homolog 2 (Drosophila)
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMC2 structural maintenance of chromosomes 2
SMC4 structural maintenance of chromosomes 4
SMYD3 SET and MYND domain containing 3
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SORBS1 sorbin and SH3 domain containing 1
SORBS2 sorbin and SH3 domain containing 2
SPRY2 sprouty homolog 2 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SQRDL sulfide quinone reductase-like (yeast)
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SSR1 signal sequence receptor, alpha
SSR4 signal sequence receptor, delta
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STIP1 stress-induced phosphoprotein 1
STK3 serine/threonine kinase 3
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUCLG1 succinate-CoA ligase, alpha subunit
SYNE2 spectrin repeat containing, nuclear envelope 2
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBC1D22A TBC1 domain family, member 22A
TBC1D22B TBC1 domain family, member 22B
TBC1D4 TBC1 domain family, member 4
TBC1D5 TBC1 domain family, member 5
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBXA2R thromboxane A2 receptor
TCP1 t-complex 1
TECR trans-2,3-enoyl-CoA reductase
TIAM1 T-cell lymphoma invasion and metastasis 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMPO thymopoietin
TOMM34 translocase of outer mitochondrial membrane 34
TOP1 topoisomerase (DNA) I
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53BP2 tumor protein p53 binding protein 2
TPD52L1 tumor protein D52-like 1
TRABD TraB domain containing
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM28 tripartite motif containing 28
TRIM32 tripartite motif containing 32
TRIP11 thyroid hormone receptor interactor 11
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TRRAP transformation/transcription domain-associated protein
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TSC22D3 TSC22 domain family, member 3
TTC27 tetratricopeptide repeat domain 27
TTC28 tetratricopeptide repeat domain 28
TTC4 tetratricopeptide repeat domain 4
TTC9C tetratricopeptide repeat domain 9C
TUBA1A tubulin, alpha 1a
TUBA4A tubulin, alpha 4a
TUBB4A tubulin, beta 4A class IVa
TUBB6 tubulin, beta 6 class V
TUBG1 tubulin, gamma 1
TUBGCP2 tubulin, gamma complex associated protein 2
U2SURP U2 snRNP-associated SURP domain containing
UBC ubiquitin C
UBE2D2 ubiquitin-conjugating enzyme E2D 2
UBE3C ubiquitin protein ligase E3C
UBR2 ubiquitin protein ligase E3 component n-recognin 2
UHRF1BP1L UHRF1 binding protein 1-like
UNC45A unc-45 homolog A (C. elegans)
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
USP19 ubiquitin specific peptidase 19
USP54 ubiquitin specific peptidase 54
USP8 ubiquitin specific peptidase 8
USP9X ubiquitin specific peptidase 9, X-linked
VAMP8 vesicle-associated membrane protein 8
VAV1 vav 1 guanine nucleotide exchange factor
VCP valosin containing protein
VDAC1 voltage-dependent anion channel 1
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
VKORC1 vitamin K epoxide reductase complex, subunit 1
VPS33B vacuolar protein sorting 33 homolog B (yeast)
WDR6 WD repeat domain 6
WDR62 WD repeat domain 62
WDR77 WD repeat domain 77
WDR83 WD repeat domain 83
WNK1 WNK lysine deficient protein kinase 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPO1 exportin 1
XPO5 exportin 5
XPOT exportin, tRNA
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
XRN1 5'-3' exoribonuclease 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
YY1 YY1 transcription factor
ZCCHC8 zinc finger, CCHC domain containing 8
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF121 zinc finger protein 121
ZNF281 zinc finger protein 281
ZNF568 zinc finger protein 568