RAI1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description retinoic acid induced 1|This gene is located within the Smith-Magenis syndrome region on chromosome 17. It is highly similar to its mouse counterpart and is expressed at high levels mainly in neuronal tissues. The protein encoded by this gene includes a polymorphic polyglutamine tract in the N-terminal domain. Expression of the mouse counterpart in neurons is induced by retinoic acid. This gene is associated with both the severity of the phenotype and the response to medication in schizophrenic patients. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 10743)
Similar Terms
Downloads & Tools

Genes

342 genes differentially expressed following the RAI1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
ALLC allantoicase 2.67333
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 2.67333
BHMT2 betaine--homocysteine S-methyltransferase 2 2.67333
TPSD1 tryptase delta 1 2.67333
C2CD4B C2 calcium-dependent domain containing 4B 2.67333
HTD2 hydroxyacyl-thioester dehydratase type 2 2.67333
MGAM maltase-glucoamylase 2.67333
VTCN1 V-set domain containing T cell activation inhibitor 1 2.67333
KLHL6 kelch-like family member 6 2.67333
EBF4 early B-cell factor 4 2.67333
SPINK4 serine peptidase inhibitor, Kazal type 4 2.67333
TMC8 transmembrane channel-like 8 2.67333
SSMEM1 serine-rich single-pass membrane protein 1 2.67333
OR2J2 olfactory receptor, family 2, subfamily J, member 2 2.67333
BATF basic leucine zipper transcription factor, ATF-like 2.67333
SLC26A4 solute carrier family 26 (anion exchanger), member 4 2.67333
MAB21L4 mab-21 like 4 2.67333
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 2.67333
FAM221B family with sequence similarity 221, member B 2.67333
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 2.64977
MROH6 maestro heat-like repeat family member 6 2.64977
TRIM74 tripartite motif containing 74 2.64977
TRIM77 tripartite motif containing 77 2.64977
CA1 carbonic anhydrase I 2.64977
BDKRB1 bradykinin receptor B1 2.64977
WNT16 wingless-type MMTV integration site family, member 16 2.64977
ASB12 ankyrin repeat and SOCS box containing 12 2.64977
ARPP21 cAMP-regulated phosphoprotein, 21kDa 2.64977
ASB4 ankyrin repeat and SOCS box containing 4 2.64977
SLC39A12 solute carrier family 39 (zinc transporter), member 12 2.64977
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.64977
SPEM1 spermatid maturation 1 2.64977
THEMIS thymocyte selection associated 2.64977
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 2.64977
TENM2 teneurin transmembrane protein 2 2.64977
CLDN14 claudin 14 2.64977
OR6J1 olfactory receptor, family 6, subfamily J, member 1 (gene/pseudogene) 2.64977
BMP3 bone morphogenetic protein 3 2.64977
CDK13 cyclin-dependent kinase 13 2.64977
SAG S-antigen; retina and pineal gland (arrestin) 2.64977
HMX1 H6 family homeobox 1 2.64977
SUSD5 sushi domain containing 5 2.64977
DLL4 delta-like 4 (Drosophila) 2.64977
MLN motilin 2.64977
RFX6 regulatory factor X, 6 2.64977
GPR101 G protein-coupled receptor 101 2.64977
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 2.64977
ZC2HC1B zinc finger, C2HC-type containing 1B 2.64977
DOK7 docking protein 7 2.64977
TKTL1 transketolase-like 1 2.64977
LTA lymphotoxin alpha 2.64977
CPNE6 copine VI (neuronal) 2.64977
ZAR1L zygote arrest 1-like 2.64977
LIPJ lipase, family member J 2.64977
TUBA3D tubulin, alpha 3d 2.64977
LGALS7B lectin, galactoside-binding, soluble, 7B 2.64977
ITK IL2-inducible T-cell kinase 2.64977
LOC107986837 uncharacterized LOC107986837 2.64977
MAG myelin associated glycoprotein 2.64977
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4 2.64977
CXCL11 chemokine (C-X-C motif) ligand 11 2.64977
OR11A1 olfactory receptor, family 11, subfamily A, member 1 2.64977
RGS21 regulator of G-protein signaling 21 2.64977
TFEC transcription factor EC 2.64977
AWAT2 acyl-CoA wax alcohol acyltransferase 2 2.64977
PIWIL1 piwi-like RNA-mediated gene silencing 1 2.64977
GJD4 gap junction protein, delta 4, 40.1kDa 2.64977
CCDC42 coiled-coil domain containing 42 2.64977
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 2.64977
TMPRSS11D transmembrane protease, serine 11D 2.64977
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 2.64977
XKR3 XK, Kell blood group complex subunit-related family, member 3 2.64977
SPATA22 spermatogenesis associated 22 2.64977
HES7 hes family bHLH transcription factor 7 2.64977
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 2.64977
CELA3A chymotrypsin-like elastase family, member 3A 2.64977
GATA6 GATA binding protein 6 2.64977
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 2.64977
TMEM176B transmembrane protein 176B 2.64977
CX3CL1 chemokine (C-X3-C motif) ligand 1 2.64977
SCN2B sodium channel, voltage gated, type II beta subunit 2.64977
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 2.64977
RNF183 ring finger protein 183 2.64977
SCGN secretagogin, EF-hand calcium binding protein 2.64977
RPL41 ribosomal protein L41 2.64977
NAPSA napsin A aspartic peptidase 2.64977
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7 2.64977
CLDN22 claudin 22 2.64977
TRIM15 tripartite motif containing 15 2.64977
TEKT1 tektin 1 2.64977
THBD thrombomodulin 2.64977
HRCT1 histidine rich carboxyl terminus 1 2.64977
CLEC18C C-type lectin domain family 18, member C 2.64977
CCL17 chemokine (C-C motif) ligand 17 2.64977
SHISA8 shisa family member 8 2.64977
FOXE3 forkhead box E3 2.64977
IFNL4 interferon, lambda 4 (gene/pseudogene) 2.64977
PLAAT2 phospholipase A and acyltransferase 2 2.64977
HUS1B HUS1 checkpoint homolog b (S. pombe) 2.64977
SPINK9 serine peptidase inhibitor, Kazal type 9 2.64977
FAM177B family with sequence similarity 177, member B 2.64977
GOLGA6D golgin A6 family, member D 2.64977
RTBDN retbindin 2.64977
RETNLB resistin like beta 2.64977
DEPP1 DEPP autophagy regulator 1 2.64977
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 2.64977
SUPT20HL2 suppressor of Ty 20 homolog (S. cerevisiae)-like 2 2.64977
MSANTD5 Myb/SANT DNA binding domain containing 5 2.64977
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 2.64977
CCDC187 coiled-coil domain containing 187 2.64977
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 2.64977
PCSK1 proprotein convertase subtilisin/kexin type 1 2.64977
SAXO3 stabilizer of axonemal microtubules 3 2.64977
LY6G6D lymphocyte antigen 6 complex, locus G6D 2.64977
MOS v-mos Moloney murine sarcoma viral oncogene homolog 2.64977
NT5C1B 5'-nucleotidase, cytosolic IB 2.64977
DLX2 distal-less homeobox 2 2.64977
THSD8 thrombospondin type 1 domain containing 8 2.64977
NT5DC4 5'-nucleotidase domain containing 4 2.64977
UTS2R urotensin 2 receptor 2.64977
ZC3H11D zinc finger CCCH-type containing 11D 2.64977
TBX2 T-box 2 2.64977
LOC124903372 uncharacterized LOC124903372 2.64977
GLO1 glyoxalase I 2.64977
EGR3 early growth response 3 2.64977
FBXO47 F-box protein 47 2.64977
FREY1 Frey regulator of sperm-oocyte fusion 1 2.64977
ZNRD2 zinc ribbon domain containing 2 2.64977
HSPB9 heat shock protein, alpha-crystallin-related, B9 2.64977
PRSS58 protease, serine, 58 2.64977
CALML5 calmodulin-like 5 2.64977
NRGN neurogranin (protein kinase C substrate, RC3) 2.64977
MORN5 MORN repeat containing 5 2.64977
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 2.64977
MYOZ2 myozenin 2 2.64977
NLRP3 NLR family, pyrin domain containing 3 2.64977
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 2.64977
MT3 metallothionein 3 2.64977
ZNF726 zinc finger protein 726 2.64977
LRRC31 leucine rich repeat containing 31 2.64977
PPP1R3A protein phosphatase 1, regulatory subunit 3A 2.64977
VN1R1 vomeronasal 1 receptor 1 2.64977
PRSS54 protease, serine, 54 2.64977
PCDHGB4 protocadherin gamma subfamily B, 4 2.64977
SLC51B solute carrier family 51, beta subunit 2.64977
FNDC1 fibronectin type III domain containing 1 2.64977
VAX2 ventral anterior homeobox 2 2.64977
ALAS2 5'-aminolevulinate synthase 2 2.64977
ANKRD30A ankyrin repeat domain 30A 2.64977
SMYD1 SET and MYND domain containing 1 2.64977
GAL3ST2 galactose-3-O-sulfotransferase 2 2.64977
FCN1 ficolin (collagen/fibrinogen domain containing) 1 2.64977
HAGH hydroxyacylglutathione hydrolase 2.63222
NAP1L2 nucleosome assembly protein 1-like 2 2.62628
NIPSNAP3B nipsnap homolog 3B (C. elegans) 2.62288
IL17D interleukin 17D 2.62288
GPAT3 glycerol-3-phosphate acyltransferase 3 2.62288
SLC26A7 solute carrier family 26 (anion exchanger), member 7 2.62288
ANKAR ankyrin and armadillo repeat containing 2.61262
MYBBP1A MYB binding protein (P160) 1a 2.60843
CRELD2 cysteine-rich with EGF-like domains 2 2.59879
BRAT1 BRCA1-associated ATM activator 1 2.57201
EIF5A eukaryotic translation initiation factor 5A 2.55218
MID1IP1 MID1 interacting protein 1 2.47139
ICA1 islet cell autoantigen 1, 69kDa 2.45674
GMCL1 germ cell-less, spermatogenesis associated 1 2.45674
LARP6 La ribonucleoprotein domain family, member 6 2.45674
CEP135 centrosomal protein 135kDa 2.45674
ANKRD52 ankyrin repeat domain 52 2.45674
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 2.44155
ICAM5 intercellular adhesion molecule 5, telencephalin 2.43241
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 2.43241
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 2.43241
ADAMTSL2 ADAMTS-like 2 2.43241
SLC46A3 solute carrier family 46, member 3 2.43241
NSD2 nuclear receptor binding SET domain protein 2 2.42219
UGT3A2 UDP glycosyltransferase 3 family, polypeptide A2 2.38124
TMEM80 transmembrane protein 80 2.37867
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 2.3641
RBP1 retinol binding protein 1, cellular 2.35593
SLC30A3 solute carrier family 30 (zinc transporter), member 3 2.3282
BMP8B bone morphogenetic protein 8b 2.32182
OR52A5 olfactory receptor, family 52, subfamily A, member 5 2.32182
MARVELD1 MARVEL domain containing 1 2.3177
RAN RAN, member RAS oncogene family 2.30138
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 2.29986
CSRNP1 cysteine-serine-rich nuclear protein 1 2.29684
BAMBI BMP and activin membrane-bound inhibitor 2.29623
CCNG1 cyclin G1 2.27742
SEC62 SEC62 homolog (S. cerevisiae) 2.2762
UTP4 UTP4 small subunit processome component 2.2762
SOD2 superoxide dismutase 2, mitochondrial 2.24471
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 2.2416
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 2.23985
PEX11B peroxisomal biogenesis factor 11 beta 2.23275
AADAT aminoadipate aminotransferase 2.2322
EGLN3 egl-9 family hypoxia-inducible factor 3 2.22644
LIMS2 LIM and senescent cell antigen-like domains 2 2.22644
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 2.22644
GPATCH8 G patch domain containing 8 2.21834
H1-5 H1.5 linker histone, cluster member 2.20037
YJU2B YJU2 splicing factor homolog B 2.18833
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 2.18189
RNH1 ribonuclease/angiogenin inhibitor 1 2.18163
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 2.16733
COMMD7 COMM domain containing 7 2.16218
SDCBP2 syndecan binding protein (syntenin) 2 2.15018
SNX8 sorting nexin 8 2.1438
SMAD7 SMAD family member 7 2.13368
GPR158 G protein-coupled receptor 158 2.12508
ZDHHC16 zinc finger, DHHC-type containing 16 2.12508
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 2.11872
ZRANB2 zinc finger, RAN-binding domain containing 2 2.11814
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) 2.09262
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 2.0906
SFRP2 secreted frizzled-related protein 2 2.08963
AHRR aryl-hydrocarbon receptor repressor 2.08963
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 2.08451
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21 2.08167
GLRA2 glycine receptor, alpha 2 2.07148
TRAPPC4 trafficking protein particle complex 4 2.06834
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 2.0675
PRMT5 protein arginine methyltransferase 5 2.06691
DCLRE1B DNA cross-link repair 1B 2.06117
AKAP7 A kinase (PRKA) anchor protein 7 2.05386
DENND1C DENN/MADD domain containing 1C 2.04012
ZNF513 zinc finger protein 513 2.03728
DERL3 derlin 3 2.0341
EML2 echinoderm microtubule associated protein like 2 2.02697
RAB25 RAB25, member RAS oncogene family 2.02013
SYT6 synaptotagmin VI 2.01129
SP8 Sp8 transcription factor 2.01129
SLC39A14 solute carrier family 39 (zinc transporter), member 14 2.01129
FAM50A family with sequence similarity 50, member A 2.00224
RPL21 ribosomal protein L21 2.00224

decreased expression

Symbol Name Standardized Value
CAMK1G calcium/calmodulin-dependent protein kinase IG -2.67333
ARHGAP9 Rho GTPase activating protein 9 -2.67333
RRH retinal pigment epithelium-derived rhodopsin homolog -2.64977
PROX1 prospero homeobox 1 -2.64977
ARID5A AT rich interactive domain 5A (MRF1-like) -2.64977
RXRA retinoid X receptor, alpha -2.64977
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 -2.64977
CDH20 cadherin 20, type 2 -2.64977
CUL7 cullin 7 -2.64402
FRS2 fibroblast growth factor receptor substrate 2 -2.63222
WASHC1 WASH complex subunit 1 -2.6267
PLSCR2 phospholipid scramblase 2 -2.58597
KIAA1328 KIAA1328 -2.53235
SAXO5 stabilizer of axonemal microtubules 5 -2.45674
THEM6 thioesterase superfamily member 6 -2.45674
ADRB2 adrenoceptor beta 2, surface -2.45674
ACOT12 acyl-CoA thioesterase 12 -2.45674
GLIPR1L2 GLI pathogenesis-related 1 like 2 -2.45674
FGFBP1 fibroblast growth factor binding protein 1 -2.45674
SP100 SP100 nuclear antigen -2.45674
ESR1 estrogen receptor 1 -2.45674
KRTAP13-4 keratin associated protein 13-4 -2.45674
BTC betacellulin -2.45674
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 -2.45674
PARP3 poly (ADP-ribose) polymerase family, member 3 -2.45674
IL22RA1 interleukin 22 receptor, alpha 1 -2.45674
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 -2.45674
GAN gigaxonin -2.45674
PDE1B phosphodiesterase 1B, calmodulin-dependent -2.45674
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 -2.45674
LRRC32 leucine rich repeat containing 32 -2.45674
MZB1 marginal zone B and B1 cell-specific protein -2.45674
PLD6 phospholipase D family, member 6 -2.45674
LORICRIN loricrin cornified envelope precursor protein -2.45674
KISS1 KiSS-1 metastasis-suppressor -2.45674
CSDC2 cold shock domain containing C2, RNA binding -2.45674
ERICH6B glutamate-rich 6B -2.45674
TEX46 testis expressed 46 -2.45674
CTAGE9 CTAGE family, member 9 -2.45674
ABLIM3 actin binding LIM protein family, member 3 -2.45674
RAG2 recombination activating gene 2 -2.45674
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) -2.45674
ASIC3 acid sensing (proton gated) ion channel 3 -2.45674
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 -2.45674
TTLL10 tubulin tyrosine ligase-like family member 10 -2.45674
GFI1B growth factor independent 1B transcription repressor -2.45674
UBE2L5 ubiquitin conjugating enzyme E2 L5 -2.45674
TICRR TOPBP1-interacting checkpoint and replication regulator -2.44935
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -2.43911
TRPC3 transient receptor potential cation channel, subfamily C, member 3 -2.42738
EIPR1 EARP complex and GARP complex interacting protein 1 -2.41035
CGNL1 cingulin-like 1 -2.3915
BCO2 beta-carotene oxygenase 2 -2.36917
NEMP2 nuclear envelope integral membrane protein 2 -2.34435
VSTM4 V-set and transmembrane domain containing 4 -2.33144
AGBL1 ATP/GTP binding protein-like 1 -2.32264
ZZZ3 zinc finger, ZZ-type containing 3 -2.30887
SPTBN1 spectrin, beta, non-erythrocytic 1 -2.30138
A2ML1 alpha-2-macroglobulin-like 1 -2.29488
ZNF79 zinc finger protein 79 -2.28202
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -2.2812
PRRT1 proline-rich transmembrane protein 1 -2.27469
ZBED8L ZBED8 like -2.25692
HSPA1B heat shock 70kDa protein 1B -2.2427
SV2A synaptic vesicle glycoprotein 2A -2.23275
COX15 cytochrome c oxidase assembly homolog 15 (yeast) -2.21998
LAT linker for activation of T cells -2.21998
ARHGAP45 Rho GTPase activating protein 45 -2.21904
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F -2.21818
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 -2.19638
HHAT hedgehog acyltransferase -2.18833
CCNB1 cyclin B1 -2.18189
RUNX1 runt-related transcription factor 1 -2.17434
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa -2.16733
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -2.16733
FGD6 FYVE, RhoGEF and PH domain containing 6 -2.16218
BTF3 basic transcription factor 3 -2.13231
ATXN7L3 ataxin 7-like 3 -2.13231
COL14A1 collagen, type XIV, alpha 1 -2.13231
STK33 serine/threonine kinase 33 -2.12813
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -2.12813
NRIP1 nuclear receptor interacting protein 1 -2.12813
FRMD4B FERM domain containing 4B -2.12533
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 -2.12004
TBC1D30 TBC1 domain family, member 30 -2.11814
ZGRF1 zinc finger, GRF-type containing 1 -2.09118
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.09118
HARBI1 harbinger transposase derived 1 -2.08963
MRS2 MRS2 magnesium transporter -2.07998
IQGAP2 IQ motif containing GTPase activating protein 2 -2.07556
PALM3 paralemmin 3 -2.07112
RNF222 ring finger protein 222 -2.0675
PSD4 pleckstrin and Sec7 domain containing 4 -2.0675
METRN meteorin, glial cell differentiation regulator -2.05565
WDR88 WD repeat domain 88 -2.05202
H4C2 H4 clustered histone 2 -2.04235
JPH2 junctophilin 2 -2.04235
ZWILCH zwilch kinetochore protein -2.04181
AP2S1 adaptor-related protein complex 2, sigma 1 subunit -2.03862
CD81 CD81 molecule -2.03655
MSI2 musashi RNA-binding protein 2 -2.02381
C2ORF68 chromosome 2 open reading frame 68 -2.02013
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.02013
MARCHF2 membrane associated ring-CH-type finger 2 -2.0114
INSL3 insulin-like 3 (Leydig cell) -2.01129
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa -2.01129
PCOLCE procollagen C-endopeptidase enhancer -2.00224