RANBP1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description RAN binding protein 1|This gene encodes a protein that forms a complex with Ras-related nuclear protein (Ran) and metabolizes guanoside triphosphate (GTP). This complex participates in the regulation of the cell cycle by controlling transport of proteins and nucleic acids into the nucleus. There are multiple pseudogenes for this gene on chromosomes 9, 12, 17, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] (NCBI Entrez Gene Database, 5902)
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Genes

348 genes differentially expressed following the RANBP1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 3.70862
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 3.70862
GJB5 gap junction protein, beta 5, 31.1kDa 3.70862
MTTP microsomal triglyceride transfer protein 3.70862
GYPB glycophorin B (MNS blood group) 3.70862
MFAP5 microfibrillar associated protein 5 3.70862
ADAD2 adenosine deaminase domain containing 2 3.70862
TNIP3 TNFAIP3 interacting protein 3 3.70862
ARSF arylsulfatase F 3.70862
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 3.70862
ADTRP androgen-dependent TFPI-regulating protein 3.70862
SIRPB1 signal-regulatory protein beta 1 3.70862
SSTR1 somatostatin receptor 1 3.70862
RASL10A RAS-like, family 10, member A 3.70862
LCE1B late cornified envelope 1B 3.70862
GPR52 G protein-coupled receptor 52 3.70862
ADGRE3 adhesion G protein-coupled receptor E3 3.70862
IZUMO3 IZUMO family member 3 3.70862
IGFL2 IGF-like family member 2 3.70862
NANOS3 nanos homolog 3 (Drosophila) 3.70862
GLUD2 glutamate dehydrogenase 2 3.70862
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1 3.70862
TRAT1 T cell receptor associated transmembrane adaptor 1 3.70862
NOTUM notum pectinacetylesterase homolog (Drosophila) 3.70862
NMUR2 neuromedin U receptor 2 3.70862
FAM9C family with sequence similarity 9, member C 3.70862
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 3.70862
STAP1 signal transducing adaptor family member 1 3.70862
DHRS9 dehydrogenase/reductase (SDR family) member 9 3.70862
RBP4 retinol binding protein 4, plasma 3.70862
WFDC11 WAP four-disulfide core domain 11 3.70862
NFE2 nuclear factor, erythroid 2 3.70862
AREG amphiregulin 3.70862
CSNK2A3 casein kinase 2, alpha 3 polypeptide 3.70862
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.70862
BHMT2 betaine--homocysteine S-methyltransferase 2 3.70862
C1ORF146 chromosome 1 open reading frame 146 3.70862
MS4A14 membrane-spanning 4-domains, subfamily A, member 14 3.70862
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 3.70862
KHDC3L KH domain containing 3-like, subcortical maternal complex member 3.70862
PRSS36 protease, serine, 36 3.70862
ADAT3 adenosine deaminase, tRNA-specific 3 3.70862
SPINK14 serine peptidase inhibitor, Kazal type 14 (putative) 3.70862
MUC22 mucin 22 3.70862
LBX2 ladybird homeobox 2 3.70862
ANKRD30B ankyrin repeat domain 30B 3.70862
LOC107986837 uncharacterized LOC107986837 3.70862
NECTIN4 nectin cell adhesion molecule 4 3.70862
PHF24 PHD finger protein 24 3.70862
GBP6 guanylate binding protein family, member 6 3.70862
GBP2 guanylate binding protein 2, interferon-inducible 3.70862
YPEL4 yippee-like 4 (Drosophila) 3.70862
GPR34 G protein-coupled receptor 34 3.70862
ZG16 zymogen granule protein 16 3.70862
FMO2 flavin containing monooxygenase 2 (non-functional) 3.70862
SMLR1 small leucine-rich protein 1 3.70862
HTD2 hydroxyacyl-thioester dehydratase type 2 3.70862
SMIM33 small integral membrane protein 33 3.70862
PLPP4 phospholipid phosphatase 4 3.70862
CIROZ ciliated left-right organizer protein containing ZP-N domains 3.70862
CIMIP4 ciliary microtubule inner protein 4 3.70862
CPNE8-AS1 CPNE8 antisense RNA 1 3.70862
DEFB109B defensin beta 109B 3.70862
LOC124902436 talanin 3.70862
STPG3 sperm-tail PG-rich repeat containing 3 3.70862
H2BC3 H2B clustered histone 3 3.70862
ELOA2 elongin A2 3.70862
ELAPOR2 endosome-lysosome associated apoptosis and autophagy regulator family member 2 3.70862
C1QTNF9B C1q and tumor necrosis factor related protein 9B 3.70862
IGSF22 immunoglobulin superfamily, member 22 3.70862
TFEC transcription factor EC 3.70862
LIX1 Lix1 homolog (chicken) 3.70862
PCDHB11 protocadherin beta 11 3.70862
DMP1 dentin matrix acidic phosphoprotein 1 3.70862
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 3.70862
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 3.70862
TARP TCR gamma alternate reading frame protein 3.70862
GPR75 G protein-coupled receptor 75 3.70862
FAM90A26 family with sequence similarity 90, member A26, pseudogene 3.70862
GDF10 growth differentiation factor 10 3.70862
RASAL3 RAS protein activator like 3 3.70862
CCR8 chemokine (C-C motif) receptor 8 3.70862
PAPOLB poly(A) polymerase beta (testis specific) 3.70862
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 3.70862
UGT2A1 UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus 3.70862
LRRC71 leucine rich repeat containing 71 3.70862
OOSP1 oocyte secreted protein 1, pseudogene 3.70862
IL1R2 interleukin 1 receptor, type II 3.70862
C9 complement component 9 3.70862
ALG10B ALG10B, alpha-1,2-glucosyltransferase 3.70862
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 3.70862
CST11 cystatin 11 3.70862
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 3.70862
C18ORF63 chromosome 18 open reading frame 63 3.70862
DYDC1 DPY30 domain containing 1 3.70862
EDN2 endothelin 2 3.70862
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 3.70862
MAGEA2B melanoma antigen family A2B 3.70862
PCDHGB2 protocadherin gamma subfamily B, 2 3.70862
HIGD2B HIG1 hypoxia inducible domain family, member 2B 3.70862
CABP5 calcium binding protein 5 3.70862
ALAS2 5'-aminolevulinate synthase 2 3.70862
PSG9 pregnancy specific beta-1-glycoprotein 9 3.70862
CD28 CD28 molecule 3.70862
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 3.70862
ORM2 orosomucoid 2 3.70862
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 3.70862
IL12A interleukin 12A 3.70862
TBC1D26 TBC1 domain family, member 26 3.70862
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 3.70862
EHF ets homologous factor 3.70862
HCRT hypocretin (orexin) neuropeptide precursor 3.70862
PATE4 prostate and testis expressed 4 3.70862
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C 3.70862
ALOXE3 arachidonate lipoxygenase 3 3.70862
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 3.70862
CPA2 carboxypeptidase A2 (pancreatic) 3.70862
TBX1 T-box 1 3.70862
SPATA4 spermatogenesis associated 4 3.70862
SPINK9 serine peptidase inhibitor, Kazal type 9 3.70862
TDRD10 tudor domain containing 10 3.70862
MORN5 MORN repeat containing 5 3.70862
NTN5 netrin 5 3.70862
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 3.70862
RESP18 regulated endocrine-specific protein 18 3.70862
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) 3.70862
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 3.70862
ADGRA1 adhesion G protein-coupled receptor A1 3.70862
PRR15L proline rich 15-like 3.70862
NRGN neurogranin (protein kinase C substrate, RC3) 3.70862
TTC24 tetratricopeptide repeat domain 24 3.70862
SLC51B solute carrier family 51, beta subunit 3.70862
GGN gametogenetin 3.70862
TMEM156 transmembrane protein 156 3.70862
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) 3.70862
GOLGA8N golgin A8 family, member N 3.70862
ANXA1 annexin A1 3.70862
ANXA8 annexin A8 3.70862
SHBG sex hormone-binding globulin 3.70862
OXER1 oxoeicosanoid (OXE) receptor 1 3.70862
AKR1C2 aldo-keto reductase family 1, member C2 3.70862
PHOX2A paired-like homeobox 2a 3.70862
NEUROD4 neuronal differentiation 4 3.70862
ZBED6 zinc finger, BED-type containing 6 3.70862
ITPKA inositol-trisphosphate 3-kinase A 3.70862
PSORS1C1 psoriasis susceptibility 1 candidate 1 3.70862
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 3.70862
FAM151A family with sequence similarity 151, member A 3.70862
SCN3A sodium channel, voltage gated, type III alpha subunit 3.70862
POU3F2 POU class 3 homeobox 2 3.70862
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 3.70862
C11ORF42 chromosome 11 open reading frame 42 3.70862
CARNS1 carnosine synthase 1 3.70862
PPP1R27 protein phosphatase 1, regulatory subunit 27 3.70862
CLCA2 chloride channel accessory 2 3.70862
APOL6 apolipoprotein L, 6 3.70862
RGN regucalcin 3.66152
INTS6 integrator complex subunit 6 3.30563
MISFA mitochondrial sheath formation associated 3.08066
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2 2.99563
ARMC10 armadillo repeat containing 10 2.94569
NHP2 NHP2 ribonucleoprotein 2.89385
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 2.82302
MMP23B matrix metallopeptidase 23B 2.78826
SPIN3 spindlin family, member 3 2.78826
ISCU iron-sulfur cluster assembly enzyme 2.78826
CNIH4 cornichon family AMPA receptor auxiliary protein 4 2.78443
ERBB4 erb-b2 receptor tyrosine kinase 4 2.72429
DDTL D-dopachrome tautomerase-like 2.65542
EIF4E1B eukaryotic translation initiation factor 4E family member 1B 2.65542
BBS5 Bardet-Biedl syndrome 5 2.65542
PRDM6 PR domain containing 6 2.65542
SPMIP8 sperm microtubule inner protein 8 2.65542
H2BC26 H2B clustered histone 26 2.65542
PVALEF parvalbumin like EF-hand containing 2.65542
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 2.65542
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) 2.62052
PDIK1L PDLIM1 interacting kinase 1 like 2.59214
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 2.56237
RSPRY1 ring finger and SPRY domain containing 1 2.53114
CEP295NL CEP295 N-terminal like 2.49898
MRPS2 mitochondrial ribosomal protein S2 2.4959
MRPL11 mitochondrial ribosomal protein L11 2.4633
AUNIP aurora kinase A and ninein interacting protein 2.43264
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 2.42907
CFL1 cofilin 1 (non-muscle) 2.40025
NAT16 N-acetyltransferase 16 (GCN5-related, putative) 2.34538
RPS19BP1 ribosomal protein S19 binding protein 1 2.34414
KLC2 kinesin light chain 2 2.33751
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase 2.33199
CTSS cathepsin S 2.3011
C17ORF114 chromosome 17 open reading frame 114 2.3011
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) 2.3011
ATP5MG ATP synthase membrane subunit g 2.3011
LUC7L3 LUC7-like 3 (S. cerevisiae) 2.3011
ABHD15 abhydrolase domain containing 15 2.3011
DND1 DND microRNA-mediated repression inhibitor 1 2.30076
CLMB calcimembrin 2.26921
ZNF532 zinc finger protein 532 2.21543
RNF185 ring finger protein 185 2.21195
ZFP37 ZFP37 zinc finger protein 2.19809
SLC39A4 solute carrier family 39 (zinc transporter), member 4 2.19014
PPM1J protein phosphatase, Mg2+/Mn2+ dependent, 1J 2.1899
VSTM2L V-set and transmembrane domain containing 2 like 2.18708
GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 2.18301
RAB23 RAB23, member RAS oncogene family 2.18058
CENPA centromere protein A 2.16496
DHRS1 dehydrogenase/reductase (SDR family) member 1 2.15738
MANF mesencephalic astrocyte-derived neurotrophic factor 2.15614
GRAMD4 GRAM domain containing 4 2.12757
HMGB1 high mobility group box 1 2.12744
PIMREG PICALM interacting mitotic regulator 2.11432
RASEF RAS and EF-hand domain containing 2.11037
H2AC8 H2A clustered histone 8 2.10639
ATXN3 ataxin 3 2.09302
GPR137B G protein-coupled receptor 137B 2.09156
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 2.09156
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 2.09026
CMC2 C-x(9)-C motif containing 2 2.08144
HLA-DRA major histocompatibility complex, class II, DR alpha 2.08144
RCE1 Ras converting CAAX endopeptidase 1 2.07703
HAUS4 HAUS augmin-like complex, subunit 4 2.07635
IGFBP6 insulin-like growth factor binding protein 6 2.07258
MKRN1 makorin ring finger protein 1 2.07134
BTF3 basic transcription factor 3 2.06856
ADRM1 adhesion regulating molecule 1 2.06406
LYRM9 LYR motif containing 9 2.06252
TRIM34 tripartite motif containing 34 2.04379
TSLIG3B tRNA splicing ligase complex subunit 3B 2.0436
PIAS1 protein inhibitor of activated STAT, 1 2.04302
SCAND1 SCAN domain containing 1 2.04288
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2.0173
BROX BRO1 domain and CAAX motif containing 2.01676
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 2.00362

decreased expression

Symbol Name Standardized Value
ICAM5 intercellular adhesion molecule 5, telencephalin -3.70862
EGFL6 EGF-like-domain, multiple 6 -3.70862
SLC46A1 solute carrier family 46 (folate transporter), member 1 -3.70862
HRH1 histamine receptor H1 -3.70862
C11ORF96 chromosome 11 open reading frame 96 -3.70862
CD22 CD22 molecule -3.70862
TBX22 T-box 22 -3.70862
JSRP1 junctional sarcoplasmic reticulum protein 1 -3.70862
CLEC4D C-type lectin domain family 4, member D -3.70862
TRPV3 transient receptor potential cation channel, subfamily V, member 3 -3.70862
VAX2 ventral anterior homeobox 2 -3.70862
DKK2 dickkopf WNT signaling pathway inhibitor 2 -3.70862
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow -3.70862
TNS2 tensin 2 -3.70862
MMP21 matrix metallopeptidase 21 -3.70862
PTGER4 prostaglandin E receptor 4 (subtype EP4) -3.70862
RUFY4 RUN and FYVE domain containing 4 -3.70862
HAS1 hyaluronan synthase 1 -3.70862
RGL4 ral guanine nucleotide dissociation stimulator-like 4 -3.70862
SPDYE5 speedy/RINGO cell cycle regulator family member E5 -3.70862
NCR1 natural cytotoxicity triggering receptor 1 -3.70862
TBX10 T-box 10 -3.70862
ARL13A ADP-ribosylation factor-like 13A -3.70862
DNAAF11 dynein axonemal assembly factor 11 -3.70862
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal -3.70862
DRC1 dynein regulatory complex subunit 1 -3.70862
SLC31A2 solute carrier family 31 (copper transporter), member 2 -3.70862
TLR5 toll-like receptor 5 -3.70862
ACOT1 acyl-CoA thioesterase 1 -3.70862
CEL carboxyl ester lipase -3.70862
ZNF816 zinc finger protein 816 -3.61345
NPIPB12 nuclear pore complex interacting protein family member B12 -3.45953
UBE3D ubiquitin protein ligase E3D -3.06871
BAX BCL2-associated X protein -3.0194
SLC4A3 solute carrier family 4 (anion exchanger), member 3 -2.93716
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F -2.91802
SRSF7 serine/arginine-rich splicing factor 7 -2.88801
SHOX short stature homeobox -2.8801
EEF2 eukaryotic translation elongation factor 2 -2.71506
CENPL centromere protein L -2.70944
SLC60A2 solute carrier family 60 member 2 -2.67361
NCEH1 neutral cholesterol ester hydrolase 1 -2.67361
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) -2.65542
CCDC92B coiled-coil domain containing 92B -2.57845
DUSP10 dual specificity phosphatase 10 -2.55513
H4C6 H4 clustered histone 6 -2.55513
MYLK4 myosin light chain kinase family, member 4 -2.55513
RANBP3L RAN binding protein 3-like -2.55513
POM121L2 POM121 transmembrane nucleoporin-like 2 -2.55513
MEI4 meiosis-specific 4 homolog (S. cerevisiae) -2.51202
SBF2 SET binding factor 2 -2.50916
MUC12 mucin 12, cell surface associated -2.49812
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 -2.4959
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 -2.42828
MYOCD myocardin -2.42056
CCDC148 coiled-coil domain containing 148 -2.41346
CFAP46 cilia and flagella associated protein 46 -2.41346
VPS13B vacuolar protein sorting 13 homolog B (yeast) -2.41146
AAK1 AP2 associated kinase 1 -2.40025
STK40 serine/threonine kinase 40 -2.39153
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 -2.32785
RCSD1 RCSD domain containing 1 -2.3011
C4ORF50 chromosome 4 open reading frame 50 -2.3011
LRRC36 leucine rich repeat containing 36 -2.3011
EMC1 ER membrane protein complex subunit 1 -2.3011
TENT5C terminal nucleotidyltransferase 5C -2.3011
H2BC13 H2B clustered histone 13 -2.3011
MATN4 matrilin 4 -2.2995
GPN1 GPN-loop GTPase 1 -2.29884
KIF5A kinesin family member 5A -2.2809
ZNF514 zinc finger protein 514 -2.27636
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -2.26921
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 -2.26921
RNF31 ring finger protein 31 -2.26921
TBX15 T-box 15 -2.26921
GBX1 gastrulation brain homeobox 1 -2.26921
HARS1 histidyl-tRNA synthetase 1 -2.26511
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 -2.25963
URM1 ubiquitin related modifier 1 -2.24357
ZNF544 zinc finger protein 544 -2.24144
MGARP mitochondria-localized glutamic acid-rich protein -2.2391
TRPV2 transient receptor potential cation channel, subfamily V, member 2 -2.2391
ENDOD1 endonuclease domain containing 1 -2.23151
ZMYM2 zinc finger, MYM-type 2 -2.21543
XPOT exportin, tRNA -2.21543
NSUN6 NOP2/Sun domain family, member 6 -2.18058
MLYCD malonyl-CoA decarboxylase -2.18058
ZNF644 zinc finger protein 644 -2.15614
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 -2.14891
LDB1 LIM domain binding 1 -2.11173
ZNF202 zinc finger protein 202 -2.10468
RIC8A RIC8 guanine nucleotide exchange factor A -2.10179
ISCA2 iron-sulfur cluster assembly 2 -2.09631
AFF4 AF4/FMR2 family, member 4 -2.09302
TRIM25 tripartite motif containing 25 -2.09122
WASF2 WAS protein family, member 2 -2.09026
MYBBP1A MYB binding protein (P160) 1a -2.09026
NAIP NLR family, apoptosis inhibitory protein -2.09026
HSPA2 heat shock 70kDa protein 2 -2.08144
GULP1 GULP, engulfment adaptor PTB domain containing 1 -2.06419
SLC9B1 solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1 -2.05829
POPDC3 popeye domain containing 3 -2.05829
AOC2 amine oxidase, copper containing 2 (retina-specific) -2.05829
ZNF837 zinc finger protein 837 -2.05426
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -2.04379
PSME3IP1 proteasome activator subunit 3 interacting protein 1 -2.0436
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 -2.0362
MTM1 myotubularin 1 -2.02954
ARL4A ADP-ribosylation factor-like 4A -2.0173
KLHL29 kelch-like family member 29 -2.01676
BRD4 bromodomain containing 4 -2.00977
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 -2.00823
MARCKS myristoylated alanine-rich protein kinase C substrate -2.00362
TACC2 transforming, acidic coiled-coil containing protein 2 -2.00362