RAP1A Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description RAP1A, member of RAS oncogene family|This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] (NCBI Entrez Gene Database, 5906)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RAP1A
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Genes

139 co-expressed genes for RAP1A from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ADGRL1 adhesion G protein-coupled receptor L1
AGPS alkylglycerone phosphate synthase
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AQP5 aquaporin 5
AQP7 aquaporin 7
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATRX alpha thalassemia/mental retardation syndrome X-linked
BAHD1 bromo adjacent homology domain containing 1
BMS1 BMS1 ribosome biogenesis factor
BPHL biphenyl hydrolase-like (serine hydrolase)
BRCA1 breast cancer 1, early onset
C1ORF216 chromosome 1 open reading frame 216
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCNF cyclin F
CDK13 cyclin-dependent kinase 13
CDYL chromodomain protein, Y-like
CEP350 centrosomal protein 350kDa
CHD3 chromodomain helicase DNA binding protein 3
CHD9 chromodomain helicase DNA binding protein 9
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CNOT2 CCR4-NOT transcription complex, subunit 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
DCK deoxycytidine kinase
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DKK4 dickkopf WNT signaling pathway inhibitor 4
DNA2 DNA replication helicase/nuclease 2
DPT dermatopontin
DTNA dystrobrevin, alpha
ECE2 endothelin converting enzyme 2
EIF4E eukaryotic translation initiation factor 4E
EIF5B eukaryotic translation initiation factor 5B
ERCC2 excision repair cross-complementation group 2
EXTL3 exostosin-like glycosyltransferase 3
FAM189A2 family with sequence similarity 189, member A2
FIG4 FIG4 phosphoinositide 5-phosphatase
FNTB farnesyltransferase, CAAX box, beta
FRYL FRY-like
GPATCH8 G patch domain containing 8
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIP2 glutamate receptor interacting protein 2
GSK3B glycogen synthase kinase 3 beta
GTSE1 G-2 and S-phase expressed 1
HIC2 hypermethylated in cancer 2
HMGN4 high mobility group nucleosomal binding domain 4
HNRNPL heterogeneous nuclear ribonucleoprotein L
HOXA11 homeobox A11
HOXD4 homeobox D4
HSPA13 heat shock protein 70kDa family, member 13
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IL13 interleukin 13
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
IPCEF1 interaction protein for cytohesin exchange factors 1
IRF2 interferon regulatory factor 2
JAG1 jagged 1
JRK Jrk homolog (mouse)
KIAA0195 KIAA0195
KIAA0586 KIAA0586
KLHDC10 kelch domain containing 10
KLHL18 kelch-like family member 18
KRT33A keratin 33A, type I
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LEPROTL1 leptin receptor overlapping transcript-like 1
LIAS lipoic acid synthetase
LPGAT1 lysophosphatidylglycerol acyltransferase 1
LSM1 LSM1, U6 small nuclear RNA associated
MC5R melanocortin 5 receptor
METTL21B methyltransferase like 21B
MFN1 mitofusin 1
MFN2 mitofusin 2
MSH3 mutS homolog 3
MSL3 male-specific lethal 3 homolog (Drosophila)
MSX1 msh homeobox 1
MT4 metallothionein 4
MYCBP MYC binding protein
NFYB nuclear transcription factor Y, beta
NKRF NFKB repressing factor
NMT1 N-myristoyltransferase 1
NR2C1 nuclear receptor subfamily 2, group C, member 1
NRTN neurturin
NUMB numb homolog (Drosophila)
OPRL1 opiate receptor-like 1
OSR1 odd-skipped related transciption factor 1
PAX9 paired box 9
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCF11 PCF11 cleavage and polyadenylation factor subunit
PCGF1 polycomb group ring finger 1
PEX3 peroxisomal biogenesis factor 3
PHF10 PHD finger protein 10
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIGF phosphatidylinositol glycan anchor biosynthesis, class F
PIGR polymeric immunoglobulin receptor
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
PPP5C protein phosphatase 5, catalytic subunit
PRIM2 primase, DNA, polypeptide 2 (58kDa)
RAP1A RAP1A, member of RAS oncogene family
RB1 retinoblastoma 1
RBBP8 retinoblastoma binding protein 8
RFC1 replication factor C (activator 1) 1, 145kDa
SCAMP1 secretory carrier membrane protein 1
SEC23IP SEC23 interacting protein
SEC31A SEC31 homolog A (S. cerevisiae)
SEC62 SEC62 homolog (S. cerevisiae)
SFSWAP splicing factor, suppressor of white-apricot family
SH2B1 SH2B adaptor protein 1
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SMC5 structural maintenance of chromosomes 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPAST spastin
SPEF1 sperm flagellar 1
SPRED2 sprouty-related, EVH1 domain containing 2
SSTR5 somatostatin receptor 5
SYNJ2 synaptojanin 2
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D22A TBC1 domain family, member 22A
TMEM11 transmembrane protein 11
TPP2 tripeptidyl peptidase II
TRIM27 tripartite motif containing 27
TTI1 TELO2 interacting protein 1
UTRN utrophin
YAF2 YY1 associated factor 2
ZBTB22 zinc finger and BTB domain containing 22
ZNF292 zinc finger protein 292
ZNF500 zinc finger protein 500