| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/RAPA_EARLY_UP.V1_UP |
| Similar Terms | |
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370 genes differentially expressed following the RAPA_EARLY_UP.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| ABCC8 | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 |
| ACOX3 | acyl-CoA oxidase 3, pristanoyl |
| ADCY10 | adenylate cyclase 10 (soluble) |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ADRA1B | adrenoceptor alpha 1B |
| AEBP1 | AE binding protein 1 |
| ALOX15 | arachidonate 15-lipoxygenase |
| AMOT | angiomotin |
| ANK1 | ankyrin 1, erythrocytic |
| ANPEP | alanyl (membrane) aminopeptidase |
| ARHGEF15 | Rho guanine nucleotide exchange factor (GEF) 15 |
| ASMT | acetylserotonin O-methyltransferase |
| ASPH | aspartate beta-hydroxylase |
| ASTN2 | astrotactin 2 |
| ATF6 | activating transcription factor 6 |
| ATG13 | autophagy related 13 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| AVPR2 | arginine vasopressin receptor 2 |
| B3GNT6 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| C2ORF72 | chromosome 2 open reading frame 72 |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) |
| CBX5 | chromobox homolog 5 |
| CCDC88C | coiled-coil domain containing 88C |
| CCDC9 | coiled-coil domain containing 9 |
| CCNG2 | cyclin G2 |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) |
| CDK10 | cyclin-dependent kinase 10 |
| CDON | cell adhesion associated, oncogene regulated |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CES1 | carboxylesterase 1 |
| CHD5 | chromodomain helicase DNA binding protein 5 |
| CHRD | chordin |
| CLCC1 | chloride channel CLIC-like 1 |
| CLDN14 | claudin 14 |
| CLK1 | CDC-like kinase 1 |
| COL5A2 | collagen, type V, alpha 2 |
| COL6A1 | collagen, type VI, alpha 1 |
| COPG2 | coatomer protein complex, subunit gamma 2 |
| CTBP2 | C-terminal binding protein 2 |
| CTSD | cathepsin D |
| CTSF | cathepsin F |
| CYP11B1 | cytochrome P450, family 11, subfamily B, polypeptide 1 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 |
| DAGLA | diacylglycerol lipase, alpha |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 |
| DLX5 | distal-less homeobox 5 |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DRD3 | dopamine receptor D3 |
| EFNA5 | ephrin-A5 |
| ESRRB | estrogen-related receptor beta |
| ETV2 | ets variant 2 |
| FABP7 | fatty acid binding protein 7, brain |
| FAM50A | family with sequence similarity 50, member A |
| FGFR2 | fibroblast growth factor receptor 2 |
| FKBP1A | FK506 binding protein 1A, 12kDa |
| FOXJ1 | forkhead box J1 |
| FPGS | folylpolyglutamate synthase |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 |
| FSCN1 | fascin actin-bundling protein 1 |
| FZD9 | frizzled class receptor 9 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 |
| GAPDHS | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic |
| GAS8 | growth arrest-specific 8 |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GMDS | GDP-mannose 4,6-dehydratase |
| GML | glycosylphosphatidylinositol anchored molecule like |
| GNAT1 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 |
| GPR182 | G protein-coupled receptor 182 |
| GPR31 | G protein-coupled receptor 31 |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
| GRK1 | G protein-coupled receptor kinase 1 |
| GRPR | gastrin-releasing peptide receptor |
| HAB1 | B1 for mucin |
| HBP1 | HMG-box transcription factor 1 |
| HCRTR2 | hypocretin (orexin) receptor 2 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
| HLA-DRB6 | major histocompatibility complex, class II, DR beta 6 (pseudogene) |
| HMBS | hydroxymethylbilane synthase |
| HOXD10 | homeobox D10 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| ICOS | inducible T-cell co-stimulator |
| INS | insulin |
| IRF7 | interferon regulatory factor 7 |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) |
| ITPKA | inositol-trisphosphate 3-kinase A |
| KCNC4 | potassium channel, voltage gated Shaw related subfamily C, member 4 |
| KIAA0040 | KIAA0040 |
| KLHL35 | kelch-like family member 35 |
| KLK6 | kallikrein-related peptidase 6 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| KRT13 | keratin 13, type I |
| KRT14 | keratin 14, type I |
| KRT19 | keratin 19, type I |
| KSR1 | kinase suppressor of ras 1 |
| L1CAM | L1 cell adhesion molecule |
| LDOC1 | leucine zipper, down-regulated in cancer 1 |
| LHX2 | LIM homeobox 2 |
| LST1 | leukocyte specific transcript 1 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MATN1 | matrilin 1, cartilage matrix protein |
| MPO | myeloperoxidase |
| MPPED1 | metallophosphoesterase domain containing 1 |
| MXRA7 | matrix-remodelling associated 7 |
| MYRF | myelin regulatory factor |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) |
| NCOA1 | nuclear receptor coactivator 1 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NINJ1 | ninjurin 1 |
| NKX2-8 | NK2 homeobox 8 |
| NPY | neuropeptide Y |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| NRL | neural retina leucine zipper |
| NUCB1 | nucleobindin 1 |
| NUDCD3 | NudC domain containing 3 |
| OLFML2A | olfactomedin-like 2A |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PART1 | prostate androgen-regulated transcript 1 (non-protein coding) |
| PDE1B | phosphodiesterase 1B, calmodulin-dependent |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PDE4A | phosphodiesterase 4A, cAMP-specific |
| PDE5A | phosphodiesterase 5A, cGMP-specific |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) |
| PIGO | phosphatidylinositol glycan anchor biosynthesis, class O |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta |
| PLA2G5 | phospholipase A2, group V |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) |
| PRKCG | protein kinase C, gamma |
| PROP1 | PROP paired-like homeobox 1 |
| PTGDR | prostaglandin D2 receptor (DP) |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| PTH2R | parathyroid hormone 2 receptor |
| PTK6 | protein tyrosine kinase 6 |
| PTPRD | protein tyrosine phosphatase, receptor type, D |
| RAD9A | RAD9 homolog A (S. pombe) |
| SCN2B | sodium channel, voltage gated, type II beta subunit |
| SEPT11 | septin 11 |
| SFPQ | splicing factor proline/glutamine-rich |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC25A42 | solute carrier family 25, member 42 |
| SLIT1 | slit homolog 1 (Drosophila) |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SOCS1 | suppressor of cytokine signaling 1 |
| SSH1 | slingshot protein phosphatase 1 |
| SST | somatostatin |
| SSUH2 | ssu-2 homolog (C. elegans) |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| SYNPO | synaptopodin |
| TAGLN3 | transgelin 3 |
| TCP10 | t-complex 10 |
| TCTA | T-cell leukemia translocation altered |
| TGM4 | transglutaminase 4 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TLE3 | transducin-like enhancer of split 3 |
| TMSB4Y | thymosin beta 4, Y-linked |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TRIM38 | tripartite motif containing 38 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked |
| VGF | VGF nerve growth factor inducible |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| VSIG4 | V-set and immunoglobulin domain containing 4 |
| VTN | vitronectin |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACHE | acetylcholinesterase (Yt blood group) |
| ACTR1B | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) |
| ACY1 | aminoacylase 1 |
| ADGRE1 | adhesion G protein-coupled receptor E1 |
| ADH6 | alcohol dehydrogenase 6 (class V) |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| AOC3 | amine oxidase, copper containing 3 |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ASMTL | acetylserotonin O-methyltransferase-like |
| ATG2A | autophagy related 2A |
| AXL | AXL receptor tyrosine kinase |
| BBC3 | BCL2 binding component 3 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial |
| BCKDK | branched chain ketoacid dehydrogenase kinase |
| BRMS1 | breast cancer metastasis suppressor 1 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit |
| CAV3 | caveolin 3 |
| CBX4 | chromobox homolog 4 |
| CCDC85B | coiled-coil domain containing 85B |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) |
| CDH22 | cadherin 22, type 2 |
| CHKB | choline kinase beta |
| CHMP3 | charged multivesicular body protein 3 |
| CIB2 | calcium and integrin binding family member 2 |
| CIT | citron rho-interacting serine/threonine kinase |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COG5 | component of oligomeric golgi complex 5 |
| COL10A1 | collagen, type X, alpha 1 |
| COL9A1 | collagen, type IX, alpha 1 |
| COL9A2 | collagen, type IX, alpha 2 |
| CRIP2 | cysteine-rich protein 2 |
| CRMP1 | collapsin response mediator protein 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| CYP2F1 | cytochrome P450, family 2, subfamily F, polypeptide 1 |
| DDN | dendrin |
| DPH1 | diphthamide biosynthesis 1 |
| DSG1 | desmoglein 1 |
| DUSP14 | dual specificity phosphatase 14 |
| DUSP2 | dual specificity phosphatase 2 |
| EDDM3A | epididymal protein 3A |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| ENG | endoglin |
| EPHB4 | EPH receptor B4 |
| ESRRA | estrogen-related receptor alpha |
| F10 | coagulation factor X |
| FAM168A | family with sequence similarity 168, member A |
| FAM182B | family with sequence similarity 182, member B |
| FAM49A | family with sequence similarity 49, member A |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FLOT1 | flotillin 1 |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| FOXI1 | forkhead box I1 |
| FTO | fat mass and obesity associated |
| FXYD1 | FXYD domain containing ion transport regulator 1 |
| GABRB1 | gamma-aminobutyric acid (GABA) A receptor, beta 1 |
| GALNS | galactosamine (N-acetyl)-6-sulfatase |
| GALR3 | galanin receptor 3 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GFRA2 | GDNF family receptor alpha 2 |
| GLUL | glutamate-ammonia ligase |
| GNRH2 | gonadotropin-releasing hormone 2 |
| GPR12 | G protein-coupled receptor 12 |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GRM2 | glutamate receptor, metabotropic 2 |
| GRN | granulin |
| GUCA2B | guanylate cyclase activator 2B (uroguanylin) |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HDAC6 | histone deacetylase 6 |
| HIST2H4A | histone cluster 2, H4a |
| HLA-E | major histocompatibility complex, class I, E |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HSPA1A | heat shock 70kDa protein 1A |
| IFI27 | interferon, alpha-inducible protein 27 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL11RA | interleukin 11 receptor, alpha |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| KDM4A | lysine (K)-specific demethylase 4A |
| KDM4B | lysine (K)-specific demethylase 4B |
| KISS1 | KiSS-1 metastasis-suppressor |
| KRT17 | keratin 17, type I |
| KRT4 | keratin 4, type II |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LHB | luteinizing hormone beta polypeptide |
| LMNA | lamin A/C |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAP1A | microtubule-associated protein 1A |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MEP1A | meprin A, alpha (PABA peptide hydrolase) |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MGST2 | microsomal glutathione S-transferase 2 |
| MICU1 | mitochondrial calcium uptake 1 |
| MID1 | midline 1 |
| MINK1 | misshapen-like kinase 1 |
| MOG | myelin oligodendrocyte glycoprotein |
| MSMO1 | methylsterol monooxygenase 1 |
| MTMR2 | myotubularin related protein 2 |
| MTMR3 | myotubularin related protein 3 |
| MUC3A | mucin 3A, cell surface associated |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NCAPH | non-SMC condensin I complex, subunit H |
| NCF1 | neutrophil cytosolic factor 1 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 |
| NHLH1 | nescient helix loop helix 1 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| NUP210 | nucleoporin 210kDa |
| NUPL2 | nucleoporin like 2 |
| OR2J2 | olfactory receptor, family 2, subfamily J, member 2 |
| OSBPL2 | oxysterol binding protein-like 2 |
| OVOL1 | ovo-like zinc finger 1 |
| PAX2 | paired box 2 |
| PCBP4 | poly(rC) binding protein 4 |
| PCSK2 | proprotein convertase subtilisin/kexin type 2 |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PHYHIP | phytanoyl-CoA 2-hydroxylase interacting protein |
| PINK1 | PTEN induced putative kinase 1 |
| PISD | phosphatidylserine decarboxylase |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLIN3 | perilipin 3 |
| PLXND1 | plexin D1 |
| PNPLA4 | patatin-like phospholipase domain containing 4 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPY | pancreatic polypeptide |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PRH2 | proline-rich protein HaeIII subfamily 2 |
| PRKCE | protein kinase C, epsilon |
| PSD | pleckstrin and Sec7 domain containing |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 |
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 |
| PTCH1 | patched 1 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| RAB5B | RAB5B, member RAS oncogene family |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 |
| RNF167 | ring finger protein 167 |
| ROR2 | receptor tyrosine kinase-like orphan receptor 2 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SEC16A | SEC16 homolog A (S. cerevisiae) |
| SELPLG | selectin P ligand |
| SERBP1 | SERPINE1 mRNA binding protein 1 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SMAD9 | SMAD family member 9 |
| SMAP1 | small ArfGAP 1 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SNTA1 | syntrophin, alpha 1 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SPRR1B | small proline-rich protein 1B |
| STK11 | serine/threonine kinase 11 |
| SYNGR4 | synaptogyrin 4 |
| TACR1 | tachykinin receptor 1 |
| TAF4 | TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TH | tyrosine hydroxylase |
| THOC1 | THO complex 1 |
| TNN | tenascin N |
| TRIM22 | tripartite motif containing 22 |
| TROAP | trophinin associated protein |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TSPAN4 | tetraspanin 4 |
| VENTXP7 | VENT homeobox pseudogene 7 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WFS1 | Wolfram syndrome 1 (wolframin) |
| WNK1 | WNK lysine deficient protein kinase 1 |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| YIPF2 | Yip1 domain family, member 2 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF175 | zinc finger protein 175 |
| ZNF3 | zinc finger protein 3 |
| ZNF799 | zinc finger protein 799 |
| ZNRF4 | zinc and ring finger 4 |
