RARA Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description retinoic acid receptor, alpha|This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010] (NCBI Entrez Gene Database, 5914)
External Link https://ncbi.nlm.nih.gov/gene/5914
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Genes

500 genes differentially expressed following the RARA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
JMJD6 jumonji domain containing 6 0.0173323
LCN2 lipocalin 2 0.016897
EGR1 early growth response 1 0.01535
GBP1 guanylate binding protein 1, interferon-inducible 0.015051
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.014082
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.0138908
IFI6 interferon, alpha-inducible protein 6 0.013239
IFI27 interferon, alpha-inducible protein 27 0.0132151
LTF lactotransferrin 0.0131161
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.0125235
IFI44L interferon-induced protein 44-like 0.0123619
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0120054
CXCL10 chemokine (C-X-C motif) ligand 10 0.0119999
CXCL8 chemokine (C-X-C motif) ligand 8 0.0116435
CXCL11 chemokine (C-X-C motif) ligand 11 0.0113441
SCG5 secretogranin V 0.0109271
PUF60 poly-U binding splicing factor 60KDa 0.0108341
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.010541
KYNU kynureninase 0.0104587
MT1X metallothionein 1X 0.0104189
IFI44 interferon-induced protein 44 0.0103025
IFRD2 interferon-related developmental regulator 2 0.00998396
GLOD4 glyoxalase domain containing 4 0.00995273
ELANE elastase, neutrophil expressed 0.00985302
SLPI secretory leukocyte peptidase inhibitor 0.00980718
S100A8 S100 calcium binding protein A8 0.00977047
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00971807
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.00965204
IFI16 interferon, gamma-inducible protein 16 0.00961764
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00956738
PLAUR plasminogen activator, urokinase receptor 0.00956639
MX1 MX dynamin-like GTPase 1 0.00947206
CNOT4 CCR4-NOT transcription complex, subunit 4 0.00946805
S100A9 S100 calcium binding protein A9 0.00938845
JCHAIN joining chain of multimeric IgA and IgM 0.00930702
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00919958
CYBB cytochrome b-245, beta polypeptide 0.00917258
GBP2 guanylate binding protein 2, interferon-inducible 0.00917005
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 0.00916213
HSPH1 heat shock 105kDa/110kDa protein 1 0.00914677
MT1G metallothionein 1G 0.00910772
SCPEP1 serine carboxypeptidase 1 0.00910168
EGR2 early growth response 2 0.00909462
BST2 bone marrow stromal cell antigen 2 0.00908621
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.00903724
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase 0.00903456
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00886362
ALOX5 arachidonate 5-lipoxygenase 0.00877752
CFB complement factor B 0.00876999
RSAD2 radical S-adenosyl methionine domain containing 2 0.00868511
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00864659
MT1HL1 metallothionein 1H-like 1 0.00864654
MT2A metallothionein 2A 0.00844477
MT1H metallothionein 1H 0.00835964
PCDH9 protocadherin 9 0.00834809
CHP1 calcineurin-like EF-hand protein 1 0.00832497
PI3 peptidase inhibitor 3, skin-derived 0.00827928
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.00827503
PDZK1IP1 PDZK1 interacting protein 1 0.00821654
ISG20 interferon stimulated exonuclease gene 20kDa 0.00813283
XAF1 XIAP associated factor 1 0.00808381
KLK6 kallikrein-related peptidase 6 0.00799571
IL15 interleukin 15 0.00790428
PITX3 paired-like homeodomain 3 0.00789098
ATF3 activating transcription factor 3 0.0078779
BHLHE41 basic helix-loop-helix family, member e41 0.00783467
PRKCA protein kinase C, alpha 0.00780352
BIK BCL2-interacting killer (apoptosis-inducing) 0.00776601
C1S complement component 1, s subcomponent 0.00775576
CXCL13 chemokine (C-X-C motif) ligand 13 0.00775488
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.00775011
BTN3A3 butyrophilin, subfamily 3, member A3 0.00769774
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.00765082
CFI complement factor I 0.00765078
IRS2 insulin receptor substrate 2 0.00760736
KRT14 keratin 14, type I 0.00760568
S100A12 S100 calcium binding protein A12 0.00756507
FOSL2 FOS-like antigen 2 0.00755423
MT1E metallothionein 1E 0.00752657
C1QB complement component 1, q subcomponent, B chain 0.00750171
CSRP1 cysteine and glycine-rich protein 1 0.00748171
NLRP2 NLR family, pyrin domain containing 2 0.00744034
CXCL9 chemokine (C-X-C motif) ligand 9 0.00741125
GLIPR1 GLI pathogenesis-related 1 0.00738215
POU2AF1 POU class 2 associating factor 1 0.00726902
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.00725538
RGS4 regulator of G-protein signaling 4 0.00719525
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00719452
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00716996
CTSS cathepsin S 0.00716641
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.00716492
GSPT2 G1 to S phase transition 2 0.0071635
MET MET proto-oncogene, receptor tyrosine kinase 0.00714042
SLCO1B3 solute carrier organic anion transporter family, member 1B3 0.00711617
CSTA cystatin A (stefin A) 0.00704124
INAVA innate immunity activator 0.00703847
MNDA myeloid cell nuclear differentiation antigen 0.00702672
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00702376
SP110 SP110 nuclear body protein 0.0069968
TRIM22 tripartite motif containing 22 0.00699382
C3 complement component 3 0.00697374
ALCAM activated leukocyte cell adhesion molecule 0.00697052
PNMA2 paraneoplastic Ma antigen 2 0.00696525
AZU1 azurocidin 1 0.00693943
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 0.00692538
C1R complement component 1, r subcomponent 0.00690874
PARP12 poly (ADP-ribose) polymerase family, member 12 0.00686931
IL18 interleukin 18 0.00685159
ZEB2 zinc finger E-box binding homeobox 2 0.00684477
FN1 fibronectin 1 0.00683899
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.00680762
CA2 carbonic anhydrase II 0.00678388
EGR3 early growth response 3 0.00677963
GFPT2 glutamine-fructose-6-phosphate transaminase 2 0.00677641
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.00676318
AIM2 absent in melanoma 2 0.00673305
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00669847
RIN2 Ras and Rab interactor 2 0.00668433
CLC Charcot-Leyden crystal galectin 0.00667591
KLK5 kallikrein-related peptidase 5 0.00667101
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.00666732
PXDN peroxidasin 0.00666688
KRT7 keratin 7, type II 0.00664213
HBEGF heparin-binding EGF-like growth factor 0.0066075
KRT5 keratin 5, type II 0.00658273
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.00658226
KLK10 kallikrein-related peptidase 10 0.00658179
DEFA4 defensin, alpha 4, corticostatin 0.00655206
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00655109
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.00653036
IRF9 interferon regulatory factor 9 0.00652733
REEP5 receptor accessory protein 5 0.00651457
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 0.00651413
WT1 Wilms tumor 1 0.00651128
CXCL6 chemokine (C-X-C motif) ligand 6 0.00648789
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.00646519
PSAP prosaposin 0.00645526
OLFM4 olfactomedin 4 0.00644679
IL32 interleukin 32 0.00643807
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 0.00641805
PRTN3 proteinase 3 0.00641772
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.00641187
MXRA7 matrix-remodelling associated 7 0.00635251
KLF2 Kruppel-like factor 2 0.00633514
SPTBN1 spectrin, beta, non-erythrocytic 1 0.00632512
LPAR6 lysophosphatidic acid receptor 6 0.00630323
NCF4 neutrophil cytosolic factor 4, 40kDa 0.00630105
GRN granulin 0.00630072
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.00630053
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.0062655
EIF5A eukaryotic translation initiation factor 5A 0.00624747
SP140L SP140 nuclear body protein-like 0.00624716
CAPN2 calpain 2, (m/II) large subunit 0.00623771
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00623324
CD69 CD69 molecule 0.00622216
RAB29 RAB29, member RAS oncogene family 0.00620448
TARP TCR gamma alternate reading frame protein 0.00619563
DOCK10 dedicator of cytokinesis 10 0.00619306
FXYD5 FXYD domain containing ion transport regulator 5 0.00619037
MCL1 myeloid cell leukemia 1 0.00618194
IRF7 interferon regulatory factor 7 0.00617095
GGT1 gamma-glutamyltransferase 1 0.00616659
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.00615985
VCAM1 vascular cell adhesion molecule 1 0.00615236
GPX1 glutathione peroxidase 1 0.00615184
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00614304
KRT15 keratin 15, type I 0.00613824
ZMPSTE24 zinc metallopeptidase STE24 0.00613108
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00613007
MSLN mesothelin 0.00610085
ELF1 E74-like factor 1 (ets domain transcription factor) 0.00608846
CTSG cathepsin G 0.00608524
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.00607833
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00606166
SOX11 SRY (sex determining region Y)-box 11 0.00604923
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.00602399
CRYAB crystallin, alpha B 0.00602175
MMP7 matrix metallopeptidase 7 0.00600731
DUSP2 dual specificity phosphatase 2 0.00598608
FCGBP Fc fragment of IgG binding protein 0.00598447
GNAS GNAS complex locus 0.00597941
S100P S100 calcium binding protein P 0.00597854
FOLR1 folate receptor 1 (adult) 0.00596292
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00592783
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.00591437
COL9A2 collagen, type IX, alpha 2 0.00590771
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.00589648
ISLR immunoglobulin superfamily containing leucine-rich repeat 0.00586803
GFAP glial fibrillary acidic protein 0.00585641
VPREB1 pre-B lymphocyte 1 0.00585457
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00580574
DPYD dihydropyrimidine dehydrogenase 0.00579999
TRIB2 tribbles pseudokinase 2 0.00579919
MT1F metallothionein 1F 0.00579871
ADI1 acireductone dioxygenase 1 0.0057961
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.00578791
ITGB4 integrin, beta 4 0.00578527
OPTN optineurin 0.0057731
CTSB cathepsin B 0.00577129
TRIP6 thyroid hormone receptor interactor 6 0.00576782
GAS1 growth arrest-specific 1 0.00576001
SAMD9 sterile alpha motif domain containing 9 0.00575853
TADA2A transcriptional adaptor 2A 0.00574853
C1QA complement component 1, q subcomponent, A chain 0.00574665
IGFBP6 insulin-like growth factor binding protein 6 0.00574504
MICB MHC class I polypeptide-related sequence B 0.00573137
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.00571692
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00569874
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00569563
CLEC5A C-type lectin domain family 5, member A 0.00567335
GPR65 G protein-coupled receptor 65 0.0056693
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.00564799
LXN latexin 0.00564524
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.00563861
TMEM255A transmembrane protein 255A 0.00561515
NVL nuclear VCP-like 0.00560916
IL7R interleukin 7 receptor 0.00560613
PADI2 peptidyl arginine deiminase, type II 0.00560474
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.00560309
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.00559844
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) 0.00559229
MINPP1 multiple inositol-polyphosphate phosphatase 1 0.00558015
THBS2 thrombospondin 2 0.00557216
F3 coagulation factor III (thromboplastin, tissue factor) 0.0055689
RIOK3 RIO kinase 3 0.0055667
DCHS1 dachsous cadherin-related 1 0.00555515
ZC3H12A zinc finger CCCH-type containing 12A 0.0055528
ANXA1 annexin A1 0.00554835
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.00554178
TRIM29 tripartite motif containing 29 0.0055205
NCF1C neutrophil cytosolic factor 1C pseudogene 0.00550797
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 0.00550538
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.00550416
LIPG lipase, endothelial 0.00549464
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.00549327
SP100 SP100 nuclear antigen 0.00547787
INHBA inhibin, beta A 0.00547501
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 0.00546811
LYPD1 LY6/PLAUR domain containing 1 0.00545827
PLBD1 phospholipase B domain containing 1 0.00545382
AKAP12 A kinase (PRKA) anchor protein 12 0.00545171
IGLL1 immunoglobulin lambda-like polypeptide 1 0.0054361
TPK1 thiamin pyrophosphokinase 1 0.00542587
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.00542297
CH25H cholesterol 25-hydroxylase 0.00541235
SLC16A4 solute carrier family 16, member 4 0.00540091
PTPRD protein tyrosine phosphatase, receptor type, D 0.00539824
PMP2 peripheral myelin protein 2 0.00539651
C1ORF54 chromosome 1 open reading frame 54 0.00539432
ITPRID2 ITPR interacting domain containing 2 0.00539278

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0306882
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.0125948
ACAT2 acetyl-CoA acetyltransferase 2 -0.0122749
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0120555
OLFM1 olfactomedin 1 -0.0119063
DLK1 delta-like 1 homolog (Drosophila) -0.0104934
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0102001
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00999017
MECOM MDS1 and EVI1 complex locus -0.00978915
TMSB15A thymosin beta 15a -0.00961601
PTK2 protein tyrosine kinase 2 -0.0092264
TFF3 trefoil factor 3 (intestinal) -0.00918231
ASRGL1 asparaginase like 1 -0.00898757
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -0.00865399
MAPK13 mitogen-activated protein kinase 13 -0.00852745
SDC2 syndecan 2 -0.00838078
CPE carboxypeptidase E -0.00835353
HOPX HOP homeobox -0.00811673
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00810446
NTS neurotensin -0.00803196
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.0079436
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 -0.00790788
GPC3 glypican 3 -0.0077645
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00765562
FASN fatty acid synthase -0.00763581
NQO2 NAD(P)H dehydrogenase, quinone 2 -0.00758248
BEX1 brain expressed, X-linked 1 -0.00756525
EPCAM epithelial cell adhesion molecule -0.00750463
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -0.00746128
SEPTIN10 septin 10 -0.00724892
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00721941
FKBP1B FK506 binding protein 1B, 12.6 kDa -0.00721438
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -0.00715829
AKR1C3 aldo-keto reductase family 1, member C3 -0.00712164
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00711936
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00691683
SEPP1 selenoprotein P, plasma, 1 -0.00684116
WBP5 WW domain binding protein 5 -0.00680794
KLHL23 kelch-like family member 23 -0.00678158
RAB25 RAB25, member RAS oncogene family -0.00676885
DEK DEK proto-oncogene -0.0067402
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.00671179
INA internexin neuronal intermediate filament protein, alpha -0.00658655
WFDC1 WAP four-disulfide core domain 1 -0.00658546
ARHGAP29 Rho GTPase activating protein 29 -0.00643405
RAPSN receptor-associated protein of the synapse -0.00639542
UPK1B uroplakin 1B -0.00637181
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 -0.00634692
PEG3 paternally expressed 3 -0.00633135
CEP43 centrosomal protein 43 -0.0062985
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.00629778
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -0.00614945
CGA glycoprotein hormones, alpha polypeptide -0.00609181
PPARG peroxisome proliferator-activated receptor gamma -0.00607861
IGFBP5 insulin-like growth factor binding protein 5 -0.00604753
DDHD2 DDHD domain containing 2 -0.00601562
FHL1 four and a half LIM domains 1 -0.00600706
GLO1 glyoxalase I -0.00600037
CIT citron rho-interacting serine/threonine kinase -0.00597686
ARMCX2 armadillo repeat containing, X-linked 2 -0.00596129
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -0.00593265
FABP4 fatty acid binding protein 4, adipocyte -0.0058905
SF3B5 splicing factor 3b, subunit 5, 10kDa -0.00586956
WIF1 WNT inhibitory factor 1 -0.00583557
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -0.0058341
TGFBR3 transforming growth factor, beta receptor III -0.00579562
CDKN3 cyclin-dependent kinase inhibitor 3 -0.00579207
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.00577725
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00576564
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00575206
EMX2 empty spiracles homeobox 2 -0.00574008
PROM1 prominin 1 -0.00572701
ZBED1 zinc finger, BED-type containing 1 -0.00572036
KIF20A kinesin family member 20A -0.00570745
GMDS GDP-mannose 4,6-dehydratase -0.00569313
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.00567331
IRS1 insulin receptor substrate 1 -0.00563587
OTUD3 OTU deubiquitinase 3 -0.00561829
CENPX centromere protein X -0.0056155
PDLIM1 PDZ and LIM domain 1 -0.00559447
CTNNBIP1 catenin, beta interacting protein 1 -0.00556615
UQCRC2 ubiquinol-cytochrome c reductase core protein II -0.00555918
FST follistatin -0.00554029
SLC35G2 solute carrier family 35, member G2 -0.00552526
PEG10 paternally expressed 10 -0.00552522
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 -0.00549386
TSPYL5 TSPY-like 5 -0.00548814
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -0.00547489
FUBP1 far upstream element (FUSE) binding protein 1 -0.00547089
CHKB choline kinase beta -0.00546777
THBS4 thrombospondin 4 -0.00546553
VKORC1 vitamin K epoxide reductase complex, subunit 1 -0.00542952
CXADR coxsackie virus and adenovirus receptor -0.00540777
INSM1 insulinoma-associated 1 -0.00540166
SLC16A6 solute carrier family 16, member 6 -0.00539977
SFTPC surfactant protein C -0.0053778
CRH corticotropin releasing hormone -0.00537227
HEBP2 heme binding protein 2 -0.00534785
SNAP25 synaptosomal-associated protein, 25kDa -0.00533791
CD99 CD99 molecule -0.00531241
MYH11 myosin, heavy chain 11, smooth muscle -0.00529588
MRTFB myocardin related transcription factor B -0.00529002
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 -0.00528987
RAD51AP1 RAD51 associated protein 1 -0.00527971
PKP4 plakophilin 4 -0.00527281
RMI1 RecQ mediated genome instability 1 -0.00525253
EMP2 epithelial membrane protein 2 -0.00524097
SH3BP4 SH3-domain binding protein 4 -0.00524034
SLC2A4RG SLC2A4 regulator -0.00522854
ASPH aspartate beta-hydroxylase -0.00522325
SPARCL1 SPARC-like 1 (hevin) -0.00520421
TP73-AS1 TP73 antisense RNA 1 -0.00520166
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -0.00518411
STK39 serine threonine kinase 39 -0.00518094
RAB40B RAB40B, member RAS oncogene family -0.00517389
SPC25 SPC25, NDC80 kinetochore complex component -0.0051586
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E -0.00514997
CD36 CD36 molecule (thrombospondin receptor) -0.00514515
HMGB3 high mobility group box 3 -0.00514483
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00514111
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.00513737
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 -0.00513199
NTAN1 N-terminal asparagine amidase -0.00512587
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma -0.00511834
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -0.00511681
TMEM204 transmembrane protein 204 -0.00508749
TBX3 T-box 3 -0.00507498
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.00506252
SPAG16 sperm associated antigen 16 -0.00506232
CHGA chromogranin A -0.00505118
ASCL1 achaete-scute family bHLH transcription factor 1 -0.0050453
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.00504249
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 -0.00502775
THAP12 THAP domain containing 12 -0.00501148
METTL5 methyltransferase like 5 -0.00500948
DYNLL1 dynein, light chain, LC8-type 1 -0.00500631
COPS4 COP9 signalosome subunit 4 -0.00500122
SHROOM2 shroom family member 2 -0.00499605
ACYP1 acylphosphatase 1, erythrocyte (common) type -0.00497383
FOXF1 forkhead box F1 -0.00496684
PHACTR2 phosphatase and actin regulator 2 -0.00495246
LDHA lactate dehydrogenase A -0.00494852
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 -0.00493954
ESR1 estrogen receptor 1 -0.00493821
P4HB prolyl 4-hydroxylase, beta polypeptide -0.00492218
UNC13B unc-13 homolog B (C. elegans) -0.00491301
ADGRA3 adhesion G protein-coupled receptor A3 -0.00491245
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -0.00490846
RELN reelin -0.00490393
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -0.00490292
SFTPA2 surfactant protein A2 -0.00490083
C3ORF14 chromosome 3 open reading frame 14 -0.00489343
TOM1L1 target of myb1 (chicken)-like 1 -0.00488147
PHTF2 putative homeodomain transcription factor 2 -0.00487095
EPS8 epidermal growth factor receptor pathway substrate 8 -0.00485872
CHN2 chimerin 2 -0.00485495
ESRP2 epithelial splicing regulatory protein 2 -0.00484489
SCML2 sex comb on midleg-like 2 (Drosophila) -0.00484272
RTN2 reticulon 2 -0.00483634
ASPN asporin -0.00483265
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -0.00482541
MEIS1 Meis homeobox 1 -0.00481768
HSDL2 hydroxysteroid dehydrogenase like 2 -0.00481619
CD248 CD248 molecule, endosialin -0.00481275
C1ORF115 chromosome 1 open reading frame 115 -0.00481055
HIC2 hypermethylated in cancer 2 -0.00480589
HAL histidine ammonia-lyase -0.00480012
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -0.00479798
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -0.00478793
HOXC10 homeobox C10 -0.00478724
CRMP1 collapsin response mediator protein 1 -0.00477648
NCKAP1 NCK-associated protein 1 -0.00472774
RNASEH2A ribonuclease H2, subunit A -0.00472718
MYO1D myosin ID -0.00472188
NELL1 NEL-like 1 (chicken) -0.00471622
ECT2 epithelial cell transforming 2 -0.00471019
ENO1 enolase 1, (alpha) -0.00470932
FGFR3 fibroblast growth factor receptor 3 -0.0047085
SCD5 stearoyl-CoA desaturase 5 -0.00469597
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -0.00469082
TRAPPC2L trafficking protein particle complex 2-like -0.00468493
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00468434
CPA3 carboxypeptidase A3 (mast cell) -0.00467135
WSB2 WD repeat and SOCS box containing 2 -0.00466771
VDAC3 voltage-dependent anion channel 3 -0.00466339
ISYNA1 inositol-3-phosphate synthase 1 -0.00466209
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 -0.00465817
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -0.00465595
PCLO piccolo presynaptic cytomatrix protein -0.00464023
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.00462492
GSTM3 glutathione S-transferase mu 3 (brain) -0.00462144
PMCH pro-melanin-concentrating hormone -0.00461665
PAQR4 progestin and adipoQ receptor family member IV -0.00460774
TWIST1 twist family bHLH transcription factor 1 -0.0046056
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) -0.00460549
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0046004
PTCH1 patched 1 -0.00459615
IL17RB interleukin 17 receptor B -0.00459101
APIP APAF1 interacting protein -0.00459058
HBB hemoglobin, beta -0.00459052
COL18A1 collagen, type XVIII, alpha 1 -0.00457666
DHDDS dehydrodolichyl diphosphate synthase -0.00457603
CDCA3 cell division cycle associated 3 -0.00455983
XYLT1 xylosyltransferase I -0.00455568
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.00455289
PPAP2A phosphatidic acid phosphatase type 2A -0.00455071
SCGN secretagogin, EF-hand calcium binding protein -0.00454912
YEATS4 YEATS domain containing 4 -0.00454789
ECI2 enoyl-CoA delta isomerase 2 -0.00454784
PRDX2 peroxiredoxin 2 -0.00454307
RPL29 ribosomal protein L29 -0.00453814
SETD3 SET domain containing 3 -0.00453674
MAN1A1 mannosidase, alpha, class 1A, member 1 -0.0045334
PLA1A phospholipase A1 member A -0.00453294
ZNF443 zinc finger protein 443 -0.00452424
LIG1 ligase I, DNA, ATP-dependent -0.00452071
HELLS helicase, lymphoid-specific -0.00451543
TESC tescalcin -0.00451342
C1ORF174 chromosome 1 open reading frame 174 -0.00450966
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 -0.00450422
BIRC5 baculoviral IAP repeat containing 5 -0.00450105
MLF1 myeloid leukemia factor 1 -0.004495
EVA1B eva-1 homolog B (C. elegans) -0.00449248
NME4 NME/NM23 nucleoside diphosphate kinase 4 -0.00447956
RNGTT RNA guanylyltransferase and 5'-phosphatase -0.00447685
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -0.00447332
ADCY2 adenylate cyclase 2 (brain) -0.00446918
AGR2 anterior gradient 2 -0.00446303
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00446263
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.00445386
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 -0.0044484
MTCL1 microtubule crosslinking factor 1 -0.0044464
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.00443607
CCNG1 cyclin G1 -0.00443154
PLIN2 perilipin 2 -0.00442168
TXNIP thioredoxin interacting protein -0.00441822
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 -0.00441212
DCTPP1 dCTP pyrophosphatase 1 -0.00441211
TMEM168 transmembrane protein 168 -0.00440707
EGLN3 egl-9 family hypoxia-inducible factor 3 -0.00438942
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.00438372
CSTB cystatin B (stefin B) -0.00436957
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00436901
MARK1 MAP/microtubule affinity-regulating kinase 1 -0.00436669
CARD8 caspase recruitment domain family, member 8 -0.00436662
MAOA monoamine oxidase A -0.00436261
MGP matrix Gla protein -0.00435817
C14ORF132 chromosome 14 open reading frame 132 -0.00433964
ADK adenosine kinase -0.00433694
DLG1 discs, large homolog 1 (Drosophila) -0.00433452