RARB Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description retinoic acid receptor, beta|This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [provided by RefSeq, Mar 2014] (NCBI Entrez Gene Database, 5915)
Similar Terms
Downloads & Tools

Genes

354 genes differentially expressed following the RARB gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PHOX2A paired-like homeobox 2a 3.30767
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 3.30767
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 3.30767
GPRC5A G protein-coupled receptor, class C, group 5, member A 3.30767
CPA3 carboxypeptidase A3 (mast cell) 3.30767
GFI1B growth factor independent 1B transcription repressor 3.30767
OASL 2'-5'-oligoadenylate synthetase-like 3.30767
CCNB3 cyclin B3 3.30767
ADRA1B adrenoceptor alpha 1B 3.30767
IL17REL interleukin 17 receptor E-like 3.30767
NR1I2 nuclear receptor subfamily 1, group I, member 2 3.30767
ALAS2 5'-aminolevulinate synthase 2 3.30767
SHISA7 shisa family member 7 3.30767
VWA3A von Willebrand factor A domain containing 3A 3.30767
IL19 interleukin 19 3.30767
UBA7 ubiquitin-like modifier activating enzyme 7 3.30767
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 3.30767
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 3.30767
SPINT4 serine peptidase inhibitor, Kunitz type 4 3.30767
CD22 CD22 molecule 3.30767
GBX1 gastrulation brain homeobox 1 3.30767
GAGE10 G antigen 10 3.30767
ADCY4 adenylate cyclase 4 3.30767
WEE2 WEE1 homolog 2 (S. pombe) 3.30767
FAM161B family with sequence similarity 161, member B 3.30767
EXD1 exonuclease 3'-5' domain containing 1 3.27241
TSGA13 testis specific, 13 3.25133
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 3.25133
CPLX1 complexin 1 3.25133
SLC26A4 solute carrier family 26 (anion exchanger), member 4 3.25133
KNG1 kininogen 1 3.25133
BSND barttin CLCNK-type chloride channel accessory beta subunit 3.25133
FGL2 fibrinogen-like 2 3.25133
HCRTR1 hypocretin (orexin) receptor 1 3.25133
SLC16A11 solute carrier family 16, member 11 3.25133
IL22RA1 interleukin 22 receptor, alpha 1 3.25133
SPINK4 serine peptidase inhibitor, Kazal type 4 3.25133
TMEM151A transmembrane protein 151A 3.25133
UNC13C unc-13 homolog C (C. elegans) 3.25133
OR1L6 olfactory receptor, family 1, subfamily L, member 6 3.25133
SKOR1 SKI family transcriptional corepressor 1 3.25133
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 3.25133
GNRHR gonadotropin-releasing hormone receptor 3.25133
MPL MPL proto-oncogene, thrombopoietin receptor 3.25133
CPLX4 complexin 4 3.25133
HIC1 hypermethylated in cancer 1 3.25133
EPHB3 EPH receptor B3 3.25133
PMCH pro-melanin-concentrating hormone 3.25133
TRPV5 transient receptor potential cation channel, subfamily V, member 5 3.25133
PTGFR prostaglandin F receptor (FP) 3.25133
AZGP1 alpha-2-glycoprotein 1, zinc-binding 3.25133
OR10A6 olfactory receptor, family 10, subfamily A, member 6 (gene/pseudogene) 3.25133
ADTRP androgen-dependent TFPI-regulating protein 3.25133
DSG3 desmoglein 3 3.25133
PLCH2 phospholipase C, eta 2 3.25133
MSC musculin 3.25133
GPR21 G protein-coupled receptor 21 3.25133
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 3.25133
C11ORF87 chromosome 11 open reading frame 87 3.25133
PCDHGA12 protocadherin gamma subfamily A, 12 3.25133
NR1H4 nuclear receptor subfamily 1, group H, member 4 3.25133
OR9H1 olfactory receptor family 9 subfamily H member 1 pseudogene (gene/pseudogene) 3.25133
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 3.25133
TTR transthyretin 3.25133
SPATA25 spermatogenesis associated 25 3.25133
ZNF705D zinc finger protein 705D 3.25133
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 3.25133
CCDC42 coiled-coil domain containing 42 3.25133
CNTN6 contactin 6 3.25133
HNF1B HNF1 homeobox B 3.25133
GDF9 growth differentiation factor 9 3.25133
PLCZ1 phospholipase C, zeta 1 3.25133
CD300LF CD300 molecule-like family member f 3.25133
MCHR2 melanin-concentrating hormone receptor 2 3.25133
ZC3H11C zinc finger CCCH-type containing 11C 3.25133
CIMAP1B ciliary microtubule associated protein 1B 3.25133
LOC124902436 talanin 3.25133
MDFIC2 MyoD family inhibitor domain containing 2 3.25133
IHO1 interactor of HORMAD1 1 3.25133
PMIS2 PMIS2 transmembrane protein 3.25133
CPHXL2 cytoplasmic polyadenylated homeobox like 2 3.25133
CFAP65 cilia and flagella associated protein 65 3.25133
SQOR sulfide quinone oxidoreductase 3.25133
HAL histidine ammonia-lyase 3.25133
OPN5 opsin 5 3.25133
IL1R1 interleukin 1 receptor, type I 3.25133
VIT vitrin 3.25133
PTPRH protein tyrosine phosphatase, receptor type, H 3.25133
HBA2 hemoglobin, alpha 2 3.25133
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 3.25133
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 3.25133
ALDOB aldolase B, fructose-bisphosphate 3.25133
TSSK4 testis-specific serine kinase 4 3.25133
HLF hepatic leukemia factor 3.25133
FOXQ1 forkhead box Q1 3.25133
SIM2 single-minded family bHLH transcription factor 2 3.25133
TLR1 toll-like receptor 1 3.25133
TLR4 toll-like receptor 4 3.25133
C9 complement component 9 3.25133
SBSN suprabasin 3.25133
INSRR insulin receptor-related receptor 3.25133
CFAP45 cilia and flagella associated protein 45 3.25133
FAP fibroblast activation protein, alpha 3.25133
KLRF1 killer cell lectin-like receptor subfamily F, member 1 3.25133
TBX3 T-box 3 3.25133
SLC45A2 solute carrier family 45, member 2 3.25133
PDE1B phosphodiesterase 1B, calmodulin-dependent 3.25133
AGTR1 angiotensin II receptor, type 1 3.25133
FIBIN fin bud initiation factor homolog (zebrafish) 3.25133
SLA2 Src-like-adaptor 2 3.25133
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 3.25133
FRZB frizzled-related protein 3.25133
APOD apolipoprotein D 3.25133
C17ORF107 chromosome 17 open reading frame 107 3.25133
PYHIN1 pyrin and HIN domain family, member 1 3.25133
FSHR follicle stimulating hormone receptor 3.25133
ITGA11 integrin, alpha 11 3.25133
TSPAN32 tetraspanin 32 3.25133
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 3.25133
SCNN1B sodium channel, non voltage gated 1 beta subunit 3.25133
CDH17 cadherin 17, LI cadherin (liver-intestine) 3.25133
MAPK10 mitogen-activated protein kinase 10 3.25133
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 3.25133
LYZ lysozyme 3.25133
IGF1 insulin-like growth factor 1 (somatomedin C) 3.25133
NLRC3 NLR family, CARD domain containing 3 3.25133
NPBWR1 neuropeptides B/W receptor 1 3.25133
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 3.25133
SHISA8 shisa family member 8 3.25133
WFDC6 WAP four-disulfide core domain 6 3.25133
TIGD3 tigger transposable element derived 3 3.25133
EVPLL envoplakin-like 3.25133
CPSF4L cleavage and polyadenylation specific factor 4-like 3.25133
CXCR4 chemokine (C-X-C motif) receptor 4 3.25133
ADGRA1 adhesion G protein-coupled receptor A1 3.25133
CCL17 chemokine (C-C motif) ligand 17 3.25133
VWA7 von Willebrand factor A domain containing 7 3.25133
ISL1 ISL LIM homeobox 1 3.25133
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 3.25133
CERKL ceramide kinase-like 3.25133
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 3.25133
SLITRK6 SLIT and NTRK-like family, member 6 3.25133
BCL2L15 BCL2-like 15 3.25133
SFTA2 surfactant associated 2 3.25133
NLRP6 NLR family, pyrin domain containing 6 3.25133
SOST sclerostin 3.25133
ZNF831 zinc finger protein 831 3.25133
GOLGA8Q golgin A8 family, member Q 3.25133
MAGEC3 melanoma antigen family C3 3.25133
GRM2 glutamate receptor, metabotropic 2 3.25133
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 3.25133
LY6G6C lymphocyte antigen 6 complex, locus G6C 3.25133
UPK1B uroplakin 1B 3.25133
SIDT1 SID1 transmembrane family, member 1 3.25133
GSDMC gasdermin C 3.25133
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 3.25133
TM4SF19 transmembrane 4 L six family member 19 3.25133
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 3.25133
PXT1 peroxisomal, testis specific 1 3.25133
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 3.25133
EFCC1 EF-hand and coiled-coil domain containing 1 3.25133
MSMP microseminoprotein, prostate associated 3.25133
TEX35 testis expressed 35 3.25133
C11ORF42 chromosome 11 open reading frame 42 3.25133
TGM6 transglutaminase 6 3.25133
GREM1 gremlin 1, DAN family BMP antagonist 3.25133
SNAI2 snail family zinc finger 2 3.25133
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 3.25133
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 3.25133
AMIGO3 adhesion molecule with Ig-like domain 3 3.25133
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 3.19223
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 3.15659
SAXO5 stabilizer of axonemal microtubules 5 3.10315
JHY junctional cadherin complex regulator 3.10315
LOC122526780 uncharacterized LOC122526780 3.10315
TRAF3 TNF receptor-associated factor 3 3.05
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 2.97739
FEM1C fem-1 homolog c (C. elegans) 2.69687
HMGN5 high mobility group nucleosome binding domain 5 2.67097
FAM219A family with sequence similarity 219, member A 2.66119
KIF5C kinesin family member 5C 2.63846
TUT7 terminal uridylyl transferase 7 2.62962
LDLRAD4 low density lipoprotein receptor class A domain containing 4 2.60735
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 2.60735
SH2D2A SH2 domain containing 2A 2.57281
C10ORF90 chromosome 10 open reading frame 90 2.57196
SV2C synaptic vesicle glycoprotein 2C 2.57196
ASNSD1 asparagine synthetase domain containing 1 2.48194
NR3C2 nuclear receptor subfamily 3, group C, member 2 2.48194
KDM5A lysine (K)-specific demethylase 5A 2.47908
LPCAT3 lysophosphatidylcholine acyltransferase 3 2.47908
SNAPIN SNAP-associated protein 2.4724
MYO1G myosin IG 2.44518
IL11 interleukin 11 2.44518
ZNF513 zinc finger protein 513 2.44518
H4C1 H4 clustered histone 1 2.43998
RAB10 RAB10, member RAS oncogene family 2.42736
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.40505
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 2.38319
C8ORF34 chromosome 8 open reading frame 34 2.38319
SHISAL2B shisa like 2B 2.36922
EEF1AKMT1 EEF1A lysine methyltransferase 1 2.36306
LMBRD1 LMBR1 domain containing 1 2.35882
ZBTB10 zinc finger and BTB domain containing 10 2.35204
CAPN11 calpain 11 2.34604
TIGAR TP53 induced glycolysis regulatory phosphatase 2.33265
ZNF677 zinc finger protein 677 2.3239
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit 2.27681
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 2.25948
SERTM1 serine-rich and transmembrane domain containing 1 2.24217
RNPC3 RNA-binding region (RNP1, RRM) containing 3 2.23718
WDR26 WD repeat domain 26 2.21759
CFAP36 cilia and flagella associated protein 36 2.21215
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa 2.19476
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 2.18833
RRP1B ribosomal RNA processing 1B 2.18833
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) 2.18144
CCHCR1 coiled-coil alpha-helical rod protein 1 2.16757
TOP1 topoisomerase (DNA) I 2.15537
MAPK4 mitogen-activated protein kinase 4 2.15537
RBM14 RNA binding motif protein 14 2.13706
MATN4 matrilin 4 2.10974
ARHGAP32 Rho GTPase activating protein 32 2.09771
B3GAT1 beta-1,3-glucuronyltransferase 1 2.09628
CALY calcyon neuron-specific vesicular protein 2.09236
FRMPD2 FERM and PDZ domain containing 2 2.09236
MPPED1 metallophosphoesterase domain containing 1 2.09236
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 2.09236
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 2.07256
MOB1A MOB kinase activator 1A 2.07256
RERG RAS-like, estrogen-regulated, growth inhibitor 2.0705
FADS2 fatty acid desaturase 2 2.06315
UBE3B ubiquitin protein ligase E3B 2.05972
PLXDC2 plexin domain containing 2 2.03292
RHPN2 rhophilin, Rho GTPase binding protein 2 2.01989
LNPK lunapark, ER junction formation factor 2.00425

decreased expression

Symbol Name Standardized Value
GPRASP3 G protein-coupled receptor associated sorting protein family member 3 -3.30767
FAM217A family with sequence similarity 217, member A -3.30767
FAM222A family with sequence similarity 222, member A -3.30767
CBX4 chromobox homolog 4 -3.30767
STMND1 stathmin domain containing 1 -3.25133
GATA3 GATA binding protein 3 -3.25133
ACSM1 acyl-CoA synthetase medium-chain family member 1 -3.25133
CXCR5 chemokine (C-X-C motif) receptor 5 -3.25133
BMX BMX non-receptor tyrosine kinase -3.25133
CXCL2 chemokine (C-X-C motif) ligand 2 -3.25133
GC group-specific component (vitamin D binding protein) -3.25133
PROZ protein Z, vitamin K-dependent plasma glycoprotein -3.25133
OR14A16 olfactory receptor, family 14, subfamily A, member 16 -3.25133
TSKS testis-specific serine kinase substrate -3.25133
TRPV2 transient receptor potential cation channel, subfamily V, member 2 -3.25133
NPSR1 neuropeptide S receptor 1 -3.25133
TRAF3IP2 TRAF3 interacting protein 2 -3.25133
SYCP3 synaptonemal complex protein 3 -3.25133
MTTP microsomal triglyceride transfer protein -3.25133
MYO16 myosin XVI -3.25133
UPB1 ureidopropionase, beta -3.25133
TP53TG5 TP53 target 5 -3.25133
NT5C3B 5'-nucleotidase, cytosolic IIIB -3.25133
FGF4 fibroblast growth factor 4 -3.25133
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent -3.25133
SPRR2F small proline-rich protein 2F -3.25133
CLDN18 claudin 18 -3.25133
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 -3.25133
RALBP1 ralA binding protein 1 -3.25133
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal -3.25133
H3-7 H3.7 histone (putative) -3.25133
FBXO43 F-box protein 43 -3.25133
H2BC13 H2B clustered histone 13 -3.25133
CCL28 chemokine (C-C motif) ligand 28 -3.25133
AMH anti-Mullerian hormone -3.25133
KASH5 KASH domain containing 5 -3.25133
PLEKHN1 pleckstrin homology domain containing, family N member 1 -3.25133
CLEC4D C-type lectin domain family 4, member D -3.25133
GPR3 G protein-coupled receptor 3 -3.21266
PHLDB1 pleckstrin homology-like domain, family B, member 1 -3.17803
FOXP4 forkhead box P4 -3.15575
LINC02762 long intergenic non-protein coding RNA 2762 -3.13692
LBR lamin B receptor -3.10282
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -3.03712
SLC38A9 solute carrier family 38, member 9 -3.01776
TFB1M transcription factor B1, mitochondrial -2.92585
CHRDL1 chordin-like 1 -2.84153
INSIG2 insulin induced gene 2 -2.78529
DENND2A DENN/MADD domain containing 2A -2.73466
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 -2.70286
SMNDC1 survival motor neuron domain containing 1 -2.67987
DTX2 deltex 2, E3 ubiquitin ligase -2.65025
AMBRA1 autophagy/beclin-1 regulator 1 -2.64033
FOXB1 forkhead box B1 -2.63744
MCRIP1 MAPK regulated corepressor interacting protein 1 -2.6244
DEF6 differentially expressed in FDCP 6 homolog (mouse) -2.61366
SNORC secondary ossification center associated regulator of chondrocyte maturation -2.61004
FRMD6 FERM domain containing 6 -2.58948
TCF12 transcription factor 12 -2.58831
DYNLT1 dynein, light chain, Tctex-type 1 -2.57196
RGS2 regulator of G-protein signaling 2 -2.57196
H4C2 H4 clustered histone 2 -2.55039
LIF leukemia inhibitory factor -2.55039
GCNT7 glucosaminyl (N-acetyl) transferase family member 7 -2.55039
GPR87 G protein-coupled receptor 87 -2.50924
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.50712
KCNK10 potassium channel, two pore domain subfamily K, member 10 -2.50555
GCHFR GTP cyclohydrolase I feedback regulator -2.50555
BATF3 basic leucine zipper transcription factor, ATF-like 3 -2.50555
DCHS1 dachsous cadherin-related 1 -2.47908
LHCGR luteinizing hormone/choriogonadotropin receptor -2.44518
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 -2.44518
POMC proopiomelanocortin -2.44518
CSNK2A1 casein kinase 2, alpha 1 polypeptide -2.44518
ACSL6 acyl-CoA synthetase long-chain family member 6 -2.44518
RTN1 reticulon 1 -2.44518
RPL26 ribosomal protein L26 -2.43091
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -2.42499
NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 -2.40387
CLCN3 chloride channel, voltage-sensitive 3 -2.39458
MRS2 MRS2 magnesium transporter -2.38592
USP50 ubiquitin specific peptidase 50 -2.38319
H3C13 H3 clustered histone 13 -2.38319
CBR3 carbonyl reductase 3 -2.38319
SPEG SPEG complex locus -2.38319
SNAP25 synaptosomal-associated protein, 25kDa -2.35882
MME membrane metallo-endopeptidase -2.35882
MAGEA4 melanoma antigen family A4 -2.35882
GAREM2 GRB2 associated regulator of MAPK1 subtype 2 -2.33018
RMI1 RecQ mediated genome instability 1 -2.31998
PRAG1 PEAK1 related, kinase-activating pseudokinase 1 -2.28585
CCDC102B coiled-coil domain containing 102B -2.27681
PSME4 proteasome (prosome, macropain) activator subunit 4 -2.25911
CHMP1A charged multivesicular body protein 1A -2.23811
CAPN1 calpain 1, (mu/I) large subunit -2.2379
GEMIN4 gem (nuclear organelle) associated protein 4 -2.2379
PRKD2 protein kinase D2 -2.23438
POU3F4 POU class 3 homeobox 4 -2.22035
PIBF1 progesterone immunomodulatory binding factor 1 -2.19422
HELB helicase (DNA) B -2.18833
NCOA3 nuclear receptor coactivator 3 -2.18206
SFT2D2 SFT2 domain containing 2 -2.16413
COASY CoA synthase -2.16315
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae) -2.15791
CMKLR2 chemerin chemokine-like receptor 2 -2.13151
RAP1A RAP1A, member of RAS oncogene family -2.12254
ZNF552 zinc finger protein 552 -2.11806
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -2.05549
RPA2 replication protein A2, 32kDa -2.05549
ARHGAP18 Rho GTPase activating protein 18 -2.04812
SLMAP sarcolemma associated protein -2.03626
ACTR6 ARP6 actin-related protein 6 homolog (yeast) -2.03585
TRAPPC4 trafficking protein particle complex 4 -2.01989
TUBGCP4 tubulin, gamma complex associated protein 4 -2.01989
RPL35 ribosomal protein L35 -2.01279
REX1BD required for excision 1-B domain containing -2.01279
CD320 CD320 molecule -2.00425
RGS17 regulator of G-protein signaling 17 -2.00425