RARG Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description retinoic acid receptor, gamma|This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 5916)
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Genes

348 genes differentially expressed following the RARG gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
IL22RA2 interleukin 22 receptor, alpha 2 2.98139
PDE3B phosphodiesterase 3B, cGMP-inhibited 2.98139
PTGFR prostaglandin F receptor (FP) 2.98139
SFTPB surfactant protein B 2.98139
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 2.98139
TMEM71 transmembrane protein 71 2.98139
OR2AJ1 olfactory receptor, family 2, subfamily AJ, member 1 2.98139
KHDC3L KH domain containing 3-like, subcortical maternal complex member 2.98139
SOWAHB sosondowah ankyrin repeat domain family member B 2.98139
SPDYE11 speedy/RINGO cell cycle regulator family member E11 2.98139
CPLX3 complexin 3 2.98139
ANKRD34A ankyrin repeat domain 34A 2.98139
TRIM73 tripartite motif containing 73 2.98139
MAGEA2 melanoma antigen family A2 2.98139
GPR151 G protein-coupled receptor 151 2.98139
HES3 hes family bHLH transcription factor 3 2.98139
APLN apelin 2.98139
GJB3 gap junction protein, beta 3, 31kDa 2.98139
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 2.98139
ARHGAP36 Rho GTPase activating protein 36 2.98139
NFAM1 NFAT activating protein with ITAM motif 1 2.98139
SLC30A2 solute carrier family 30 (zinc transporter), member 2 2.98139
C19ORF67 chromosome 19 open reading frame 67 2.98139
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 2.98139
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.98139
RNF39 ring finger protein 39 2.98139
NLRP6 NLR family, pyrin domain containing 6 2.98139
ANGPTL3 angiopoietin-like 3 2.98139
SLX1B SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) 2.98139
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 2.98139
TGM6 transglutaminase 6 2.98139
TTC36 tetratricopeptide repeat domain 36 2.98139
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 2.98139
TEX38 testis expressed 38 2.98139
TMPRSS13 transmembrane protease, serine 13 2.98139
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 2.98139
ASCL1 achaete-scute family bHLH transcription factor 1 2.98139
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2.98139
FGF9 fibroblast growth factor 9 2.98139
CCDC87 coiled-coil domain containing 87 2.98139
CCDC83 coiled-coil domain containing 83 2.98139
PRSS21 protease, serine, 21 (testisin) 2.98139
EBI3 Epstein-Barr virus induced 3 2.98139
CTAG2 cancer/testis antigen 2 2.98139
GRM6 glutamate receptor, metabotropic 6 2.98139
ANXA2R annexin A2 receptor 2.98139
CD3D CD3d molecule, delta (CD3-TCR complex) 2.98139
OR6B1 olfactory receptor, family 6, subfamily B, member 1 2.98139
TMEM156 transmembrane protein 156 2.98139
LRTM3 leucine rich repeat transmembrane protein 3 2.98139
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 2.98139
ACSL5 acyl-CoA synthetase long-chain family member 5 2.98139
ADRB1 adrenoceptor beta 1 2.98139
OR51M1 olfactory receptor, family 51, subfamily M, member 1 2.98139
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 2.98139
GATA2 GATA binding protein 2 2.98139
CSAG2 CSAG family, member 2 2.98139
LTK leukocyte receptor tyrosine kinase 2.98139
IL16 interleukin 16 2.98139
PRG4 proteoglycan 4 2.98139
C9ORF43 chromosome 9 open reading frame 43 2.98139
CLDN16 claudin 16 2.98139
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 2.98139
ZC3H11C zinc finger CCCH-type containing 11C 2.98139
FAM240C family with sequence similarity 240 member C 2.98139
H2BK1 H2B.K variant histone 1 2.98139
H4C15 H4 clustered histone 15 2.98139
GLYATL1B glycine-N-acyltransferase like 1B 2.98139
ACP4 acid phosphatase 4 2.98139
TENT5D terminal nucleotidyltransferase 5D 2.98139
KASH5 KASH domain containing 5 2.98139
GBP3 guanylate binding protein 3 2.98139
PCDHGC3 protocadherin gamma subfamily C, 3 2.98139
SAA4 serum amyloid A4, constitutive 2.98139
UTS2 urotensin 2 2.98139
SLC35D3 solute carrier family 35, member D3 2.98139
TAS2R5 taste receptor, type 2, member 5 2.98139
HNF4A hepatocyte nuclear factor 4, alpha 2.98139
HLF hepatic leukemia factor 2.98139
SLFN11 schlafen family member 11 2.98139
CST11 cystatin 11 2.98139
CD6 CD6 molecule 2.98139
LY86 lymphocyte antigen 86 2.98139
TREM1 triggering receptor expressed on myeloid cells 1 2.98139
RAB9B RAB9B, member RAS oncogene family 2.98139
PCDHA3 protocadherin alpha 3 2.98139
GGT5 gamma-glutamyltransferase 5 2.98139
NR0B1 nuclear receptor subfamily 0, group B, member 1 2.98139
GSC goosecoid homeobox 2.98139
TCF23 transcription factor 23 2.98139
C1QTNF9 C1q and tumor necrosis factor related protein 9 2.98139
AWAT1 acyl-CoA wax alcohol acyltransferase 1 2.98139
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.98139
MSX2 msh homeobox 2 2.98139
OR51B5 olfactory receptor, family 51, subfamily B, member 5 2.98139
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 2.98139
MAGEB3 melanoma antigen family B3 2.98139
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 2.98139
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 2.98139
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 2.98139
WFDC8 WAP four-disulfide core domain 8 2.98139
ADAM2 ADAM metallopeptidase domain 2 2.98139
C11ORF16 chromosome 11 open reading frame 16 2.98139
SLC38A3 solute carrier family 38, member 3 2.98139
MEFV Mediterranean fever 2.98139
TREH trehalase (brush-border membrane glycoprotein) 2.98139
APOC4 apolipoprotein C-IV 2.98139
LGALS12 lectin, galactoside-binding, soluble, 12 2.98139
CYSLTR1 cysteinyl leukotriene receptor 1 2.98139
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 2.98139
CDC20B cell division cycle 20B 2.98139
CST4 cystatin S 2.98139
SERPINB12 serpin peptidase inhibitor, clade B (ovalbumin), member 12 2.98139
GRK1 G protein-coupled receptor kinase 1 2.98139
THTPA thiamine triphosphatase 2.98139
BTNL3 butyrophilin-like 3 2.98139
TRIM7 tripartite motif containing 7 2.98139
TRIM50 tripartite motif containing 50 2.98139
IRGM immunity-related GTPase family, M 2.98139
TTC9B tetratricopeptide repeat domain 9B 2.98139
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 2.98139
PDZRN4 PDZ domain containing ring finger 4 2.98139
FBXO40 F-box protein 40 2.98139
C8G complement component 8, gamma polypeptide 2.98139
BEAN1 brain expressed, associated with NEDD4, 1 2.98139
SMIM23 small integral membrane protein 23 2.98139
MAGED4B melanoma antigen family D4B 2.98139
PDCD1LG2 programmed cell death 1 ligand 2 2.98139
PRSS33 protease, serine, 33 2.98139
ZCCHC12 zinc finger, CCHC domain containing 12 2.98139
DRD5 dopamine receptor D5 2.98139
SHISA8 shisa family member 8 2.98139
EVPLL envoplakin-like 2.98139
PRH2 proline-rich protein HaeIII subfamily 2 2.98139
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 2.98139
IL19 interleukin 19 2.98139
PCDH12 protocadherin 12 2.98139
HOPX HOP homeobox 2.98139
GFRAL GDNF family receptor alpha like 2.98139
NKX6-2 NK6 homeobox 2 2.98139
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 2.98139
DMTN dematin actin binding protein 2.98139
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.98139
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 2.98139
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.98139
ZMYND15 zinc finger, MYND-type containing 15 2.98139
ZNF474 zinc finger protein 474 2.98139
OR3A1 olfactory receptor, family 3, subfamily A, member 1 2.98139
OR9Q1 olfactory receptor, family 9, subfamily Q, member 1 2.98139
GOLGA8R golgin A8 family, member R 2.98139
PCDHGB5 protocadherin gamma subfamily B, 5 2.98139
NTSR2 neurotensin receptor 2 2.98139
CLCA1 chloride channel accessory 1 2.98139
PATE1 prostate and testis expressed 1 2.98139
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 2.98139
ADGRF1 adhesion G protein-coupled receptor F1 2.98139
DMRTB1 DMRT-like family B with proline-rich C-terminal, 1 2.98139
SUN3 Sad1 and UNC84 domain containing 3 2.98139
C9ORF57 chromosome 9 open reading frame 57 2.98139
DBX2 developing brain homeobox 2 2.98139
MAPK11 mitogen-activated protein kinase 11 2.98139
PRSS54 protease, serine, 54 2.98139
TEX28 testis expressed 28 2.98139
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 2.98139
GFI1B growth factor independent 1B transcription repressor 2.98139
KLHDC1 kelch domain containing 1 2.98139
SPATA19 spermatogenesis associated 19 2.98139
PCDHGB2 protocadherin gamma subfamily B, 2 2.98139
RIPK3 receptor-interacting serine-threonine kinase 3 2.98139
LRRN4 leucine rich repeat neuronal 4 2.98139
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 2.98139
POU4F1 POU class 4 homeobox 1 2.98139
CH25H cholesterol 25-hydroxylase 2.98139
FKBP1C FK506 binding protein 1C 2.98139
AP5S1 adaptor-related protein complex 5, sigma 1 subunit 2.98049
AKR1C1 aldo-keto reductase family 1, member C1 2.98049
GOLGA6C golgin A6 family, member C 2.86877
PDCL2 phosducin-like 2 2.86877
PSMC3IP PSMC3 interacting protein 2.86423
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 2.8468
KLC4 kinesin light chain 4 2.83227
ANKRD13D ankyrin repeat domain 13 family, member D 2.80384
ASXL3 additional sex combs like transcriptional regulator 3 2.77509
CAND1 cullin-associated and neddylation-dissociated 1 2.75892
MYADM myeloid-associated differentiation marker 2.73838
FBXO2 F-box protein 2 2.73784
SOAT1 sterol O-acyltransferase 1 2.67556
CFAP95 cilia and flagella associated protein 95 2.48919
CELF2 CUGBP, Elav-like family member 2 2.4493
IL12A interleukin 12A 2.44719
PARVG parvin, gamma 2.44719
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 2.44719
ZNF773 zinc finger protein 773 2.44719
PTPN20 protein tyrosine phosphatase, non-receptor type 20 2.44719
MRPL15 mitochondrial ribosomal protein L15 2.44719
ANGPT4 angiopoietin 4 2.44719
HDAC11 histone deacetylase 11 2.44719
DORIP1 dopamine receptor interacting protein 1 2.42419
POFUT2 protein O-fucosyltransferase 2 2.42301
UBAP1 ubiquitin associated protein 1 2.39622
SAMD14 sterile alpha motif domain containing 14 2.33744
CFAP53 cilia and flagella associated protein 53 2.33614
PCM1 pericentriolar material 1 2.33423
ZSWIM9 zinc finger SWIM-type containing 9 2.29965
FGF1 fibroblast growth factor 1 (acidic) 2.28949
STX3 syntaxin 3 2.26767
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 2.26767
PNLDC1 poly(A)-specific ribonuclease (PARN)-like domain containing 1 2.26767
RIPOR2 RHO family interacting cell polarization regulator 2 2.26692
KLHL28 kelch-like family member 28 2.26534
CHCHD6 coiled-coil-helix-coiled-coil-helix domain containing 6 2.25342
ITGA7 integrin, alpha 7 2.20397
CLCN1 chloride channel, voltage-sensitive 1 2.20066
KY kyphoscoliosis peptidase 2.17135
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) 2.17075
FOXN3 forkhead box N3 2.16598
WDPCP WD repeat containing planar cell polarity effector 2.1543
TMEM127 transmembrane protein 127 2.1532
ETAA1 Ewing tumor-associated antigen 1 2.14784
RAMP2 receptor (G protein-coupled) activity modifying protein 2 2.14528
RCN1 reticulocalbin 1, EF-hand calcium binding domain 2.12774
CREBRF CREB3 regulatory factor 2.12318
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 2.11663
SNAP23 synaptosomal-associated protein, 23kDa 2.09948
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.09637
BAIAP2 BAI1-associated protein 2 2.08098
BAG4 BCL2-associated athanogene 4 2.07977
DCXR dicarbonyl/L-xylulose reductase 2.07502
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) 2.0576
AMH anti-Mullerian hormone 2.02975
FOS FBJ murine osteosarcoma viral oncogene homolog 2.02303
FANCC Fanconi anemia, complementation group C 2.02303
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa 2.02293
CDK19 cyclin-dependent kinase 19 2.02139
PCOLCE2 procollagen C-endopeptidase enhancer 2 2.01983
BMP2K BMP2 inducible kinase 2.01771
H2AC16 H2A clustered histone 16 2.01579
DPYSL4 dihydropyrimidinase-like 4 2.00475

decreased expression

Symbol Name Standardized Value
ASB17 ankyrin repeat and SOCS box containing 17 -2.98139
TRIM15 tripartite motif containing 15 -2.98139
MUC6 mucin 6, oligomeric mucus/gel-forming -2.98139
RAX retina and anterior neural fold homeobox -2.98139
FAM177B family with sequence similarity 177, member B -2.98139
MYCT1 myc target 1 -2.98139
RAB21 RAB21, member RAS oncogene family -2.98139
MAMDC4 MAM domain containing 4 -2.98139
KCNK9 potassium channel, two pore domain subfamily K, member 9 -2.98139
LRRC43 leucine rich repeat containing 43 -2.98139
CD68 CD68 molecule -2.98139
LGALS2 lectin, galactoside-binding, soluble, 2 -2.98139
PROM2 prominin 2 -2.98139
CSF3R colony stimulating factor 3 receptor (granulocyte) -2.98139
PCDHGA12 protocadherin gamma subfamily A, 12 -2.98139
FAM81B family with sequence similarity 81, member B -2.98139
RP1 retinitis pigmentosa 1 (autosomal dominant) -2.98139
CHP2 calcineurin-like EF-hand protein 2 -2.98139
GNLY granulysin -2.98139
CARD14 caspase recruitment domain family, member 14 -2.98139
CHADL chondroadherin-like -2.98139
MFSD2B major facilitator superfamily domain containing 2B -2.98139
MRPL9 mitochondrial ribosomal protein L9 -2.98139
MYEOV myeloma overexpressed -2.98139
SP140L SP140 nuclear body protein-like -2.98139
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -2.98139
STYXL2 serine/threonine/tyrosine interacting like 2 -2.98139
ART3 ADP-ribosyltransferase 3 -2.98139
ANGPTL8 angiopoietin like 8 -2.98139
LCAT lecithin-cholesterol acyltransferase -2.98139
C1ORF87 chromosome 1 open reading frame 87 -2.98139
ELF4 E74-like factor 4 (ets domain transcription factor) -2.98139
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) -2.98139
UTS2B urotensin 2B -2.98139
CTXN2 cortexin 2 -2.98139
ETV7 ets variant 7 -2.98139
VSTM1 V-set and transmembrane domain containing 1 -2.98139
CFAP61 cilia and flagella associated protein 61 -2.98139
HRH4 histamine receptor H4 -2.98139
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -2.92487
ADORA2B adenosine A2b receptor -2.92269
RBM8A RNA binding motif protein 8A -2.91066
GABARAP GABA(A) receptor-associated protein -2.88514
LTB4R leukotriene B4 receptor -2.87432
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) -2.87432
BRME1 break repair meiotic recombinase recruitment factor 1 -2.85376
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.7837
TXNDC11 thioredoxin domain containing 11 -2.73012
FDX2 ferredoxin 2 -2.6526
PTPRM protein tyrosine phosphatase, receptor type, M -2.62063
RORC RAR-related orphan receptor C -2.57496
CRHR1 corticotropin releasing hormone receptor 1 -2.57496
SRCIN1 SRC kinase signaling inhibitor 1 -2.53229
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 -2.46134
DPY30 dpy-30 homolog (C. elegans) -2.45196
RBMX RNA binding motif protein, X-linked -2.44719
CATSPER2 cation channel, sperm associated 2 -2.44013
LPAR2 lysophosphatidic acid receptor 2 -2.43145
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 -2.42301
CMTR1 cap methyltransferase 1 -2.42301
PITRM1 pitrilysin metallopeptidase 1 -2.4006
SIGMAR1 sigma non-opioid intracellular receptor 1 -2.38176
EMSY EMSY transcriptional repressor, BRCA2 interacting -2.37971
FIRRM FIGNL1 interacting regulator of recombination and mitosis -2.36481
NEK11 NIMA-related kinase 11 -2.35199
CLK3 CDC-like kinase 3 -2.34444
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.33744
TTC28 tetratricopeptide repeat domain 28 -2.33744
C11ORF71 chromosome 11 open reading frame 71 -2.30466
VWA5B1 von Willebrand factor A domain containing 5B1 -2.28472
ZNF335 zinc finger protein 335 -2.28472
STK33 serine/threonine kinase 33 -2.26767
SLC66A2 solute carrier family 66 member 2 -2.26767
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) -2.25421
APOC1 apolipoprotein C-I -2.25122
ANKRD61 ankyrin repeat domain 61 -2.24257
GADD45B growth arrest and DNA-damage-inducible, beta -2.21472
INHA inhibin, alpha -2.20603
COQ10A coenzyme Q10 homolog A (S. cerevisiae) -2.19501
POLH polymerase (DNA directed), eta -2.17284
DACT2 dishevelled-binding antagonist of beta-catenin 2 -2.1598
SOD1 superoxide dismutase 1, soluble -2.1598
MTAP methylthioadenosine phosphorylase -2.15176
RPL11 ribosomal protein L11 -2.14525
ACMSD aminocarboxymuconate semialdehyde decarboxylase -2.14175
PUSL1 pseudouridylate synthase-like 1 -2.13166
MX1 MX dynamin-like GTPase 1 -2.13166
KIFC2 kinesin family member C2 -2.13166
TNC tenascin C -2.13166
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -2.12774
OBSL1 obscurin-like 1 -2.1251
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog -2.12318
TNIP1 TNFAIP3 interacting protein 1 -2.12256
TMX2 thioredoxin-related transmembrane protein 2 -2.12235
TNRC6B trinucleotide repeat containing 6B -2.11663
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -2.09956
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 -2.08599
PPP1R10 protein phosphatase 1, regulatory subunit 10 -2.07502
GPATCH1 G patch domain containing 1 -2.05557
NUP42 nucleoporin 42 -2.05357
JARID2 jumonji, AT rich interactive domain 2 -2.02975
FASTKD2 FAST kinase domains 2 -2.02912
RLN2 relaxin 2 -2.02912
KCTD2 potassium channel tetramerization domain containing 2 -2.0255
PLD1 phospholipase D1, phosphatidylcholine-specific -2.02303
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -2.0203
KBTBD2 kelch repeat and BTB (POZ) domain containing 2 -2.01983
MAN1B1 mannosidase, alpha, class 1B, member 1 -2.01677
AP2B1 adaptor-related protein complex 2, beta 1 subunit -2.00401
SLC68A1 solute carrier family 68 member 1 -2.00401