| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | retinoblastoma 1|The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5925) |
| External Link | https://ncbi.nlm.nih.gov/gene/5925 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the RB1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | 0.0244946 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0181955 |
| RRAGA | Ras-related GTP binding A | 0.015448 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0125513 |
| PEG10 | paternally expressed 10 | 0.0118625 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.0108823 |
| KRT7 | keratin 7, type II | 0.0106043 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.0103943 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | 0.0102645 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.0101116 |
| TNS3 | tensin 3 | 0.00977631 |
| FN1 | fibronectin 1 | 0.00977152 |
| NPY1R | neuropeptide Y receptor Y1 | 0.00936212 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | 0.00934736 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00920461 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00920452 |
| BCHE | butyrylcholinesterase | 0.00905218 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00903966 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00884231 |
| ASPN | asporin | 0.00883446 |
| JMJD6 | jumonji domain containing 6 | 0.00865454 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | 0.00861853 |
| PNN | pinin, desmosome associated protein | 0.0083421 |
| PTK2 | protein tyrosine kinase 2 | 0.00828525 |
| MXRA7 | matrix-remodelling associated 7 | 0.00819588 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | 0.00814812 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00811537 |
| LUM | lumican | 0.0080307 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00800673 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00800534 |
| IRS2 | insulin receptor substrate 2 | 0.00797376 |
| TCF4 | transcription factor 4 | 0.00789606 |
| WDR7 | WD repeat domain 7 | 0.00778966 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00771051 |
| CA2 | carbonic anhydrase II | 0.00770958 |
| STK26 | serine/threonine protein kinase 26 | 0.00768138 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00759506 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.00752188 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0074446 |
| CYTL1 | cytokine-like 1 | 0.00742142 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00739949 |
| COL16A1 | collagen, type XVI, alpha 1 | 0.00738678 |
| CTSK | cathepsin K | 0.00736767 |
| NPIPA1 | nuclear pore complex interacting protein family, member A1 | 0.00734991 |
| HMOX1 | heme oxygenase 1 | 0.00734801 |
| TSPAN4 | tetraspanin 4 | 0.00733161 |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.00732577 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | 0.00730259 |
| SMAD7 | SMAD family member 7 | 0.00727272 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.00726973 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00719177 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00716624 |
| HHEX | hematopoietically expressed homeobox | 0.00711904 |
| PLEC | plectin | 0.00705054 |
| XIC | X chromosome inactivation center | 0.00703337 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.00703332 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00692056 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 0.00687113 |
| TPSAB1 | tryptase alpha/beta 1 | 0.00669225 |
| WDR26 | WD repeat domain 26 | 0.00668416 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0066644 |
| PILRB | paired immunoglobin-like type 2 receptor beta | 0.0066151 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.00651822 |
| CST6 | cystatin E/M | 0.00651526 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00651023 |
| PLK1 | polo-like kinase 1 | 0.00649612 |
| TXNL4A | thioredoxin-like 4A | 0.00647254 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.0064631 |
| GDF15 | growth differentiation factor 15 | 0.00637117 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00635617 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00635255 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00631558 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | 0.00631244 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.00628577 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00626313 |
| MMP1 | matrix metallopeptidase 1 | 0.00625061 |
| HOPX | HOP homeobox | 0.00621292 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00620051 |
| ODC1 | ornithine decarboxylase 1 | 0.00613153 |
| IRS1 | insulin receptor substrate 1 | 0.00612727 |
| PFN2 | profilin 2 | 0.00612192 |
| CSAD | cysteine sulfinic acid decarboxylase | 0.00611853 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 | 0.00610407 |
| PRPF4B | pre-mRNA processing factor 4B | 0.00609498 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00607422 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00603178 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00599128 |
| OLFML2A | olfactomedin-like 2A | 0.00594757 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00593022 |
| MIA | melanoma inhibitory activity | 0.00592417 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 0.0059165 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | 0.00590564 |
| MATN2 | matrilin 2 | 0.00589577 |
| PLXNA2 | plexin A2 | 0.00587935 |
| CCNA2 | cyclin A2 | 0.00586936 |
| SQLE | squalene epoxidase | 0.00586827 |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | 0.00584697 |
| EMP1 | epithelial membrane protein 1 | 0.00584594 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00583632 |
| GOLGA4 | golgin A4 | 0.00581564 |
| PNMA8A | PNMA family member 8A | 0.0058083 |
| CCNL2 | cyclin L2 | 0.00578997 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | 0.00578438 |
| TXLNA | taxilin alpha | 0.00577663 |
| KRT17 | keratin 17, type I | 0.00577488 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00575849 |
| RGS16 | regulator of G-protein signaling 16 | 0.00575721 |
| RGS5 | regulator of G-protein signaling 5 | 0.00571851 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00570462 |
| SGCE | sarcoglycan, epsilon | 0.00570125 |
| SH2B1 | SH2B adaptor protein 1 | 0.00567453 |
| MMP11 | matrix metallopeptidase 11 | 0.00566781 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.00566588 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00562085 |
| MIR22HG | MIR22 host gene | 0.00561386 |
| PXDC1 | PX domain containing 1 | 0.00561309 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00560044 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00559896 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.00559345 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.00558634 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.00557684 |
| IFI44L | interferon-induced protein 44-like | 0.00557477 |
| THOC2 | THO complex 2 | 0.00556663 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.005555 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00554757 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.00554027 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00552232 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.00551694 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 0.0055043 |
| RBBP6 | retinoblastoma binding protein 6 | 0.00550364 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00550052 |
| ZNF512B | zinc finger protein 512B | 0.00548546 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.00544448 |
| PLD3 | phospholipase D family, member 3 | 0.00543092 |
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 0.0054308 |
| S100A2 | S100 calcium binding protein A2 | 0.00539045 |
| ECM1 | extracellular matrix protein 1 | 0.00538344 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | 0.0053724 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00536825 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 0.00536068 |
| EDRF1 | erythroid differentiation regulatory factor 1 | 0.00535655 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.00535321 |
| SETD5 | SET domain containing 5 | 0.00534082 |
| STIP1 | stress-induced phosphoprotein 1 | 0.00533752 |
| LAMB2 | laminin, beta 2 (laminin S) | 0.00533262 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00532853 |
| PDHX | pyruvate dehydrogenase complex, component X | 0.00532597 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | 0.00532233 |
| INHBB | inhibin, beta B | 0.00531244 |
| CLGN | calmegin | 0.0052911 |
| KLC1 | kinesin light chain 1 | 0.00528119 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00527983 |
| CCN2 | cellular communication network factor 2 | 0.00527621 |
| MAGED1 | melanoma antigen family D1 | 0.00526543 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.00525055 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00524009 |
| NXN | nucleoredoxin | 0.00523983 |
| VEGFC | vascular endothelial growth factor C | 0.00523752 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.00523351 |
| PCDH9 | protocadherin 9 | 0.00522771 |
| YBX1 | Y box binding protein 1 | 0.00521527 |
| UBL3 | ubiquitin-like 3 | 0.00520691 |
| NVL | nuclear VCP-like | 0.0052066 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | 0.00520462 |
| BTG2 | BTG family, member 2 | 0.00519219 |
| DCLK1 | doublecortin-like kinase 1 | 0.0051916 |
| KANK2 | KN motif and ankyrin repeat domains 2 | 0.0051909 |
| RCL1 | RNA terminal phosphate cyclase-like 1 | 0.00518673 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.00517433 |
| METTL3 | methyltransferase like 3 | 0.00517412 |
| TASOR2 | transcription activation suppressor family member 2 | 0.00517399 |
| RPL10 | ribosomal protein L10 | 0.00516885 |
| OTUD4 | OTU deubiquitinase 4 | 0.00516351 |
| COL7A1 | collagen, type VII, alpha 1 | 0.00516194 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00515972 |
| SCRIB | scribbled planar cell polarity protein | 0.00515132 |
| WT1 | Wilms tumor 1 | 0.00512271 |
| PLCE1 | phospholipase C, epsilon 1 | 0.00511576 |
| OGN | osteoglycin | 0.00510947 |
| INHBE | inhibin, beta E | 0.00510716 |
| LAMB1 | laminin, beta 1 | 0.0051054 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00510449 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00509988 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.00509327 |
| GOLGA8A | golgin A8 family, member A | 0.00508577 |
| VEGFA | vascular endothelial growth factor A | 0.0050723 |
| CPE | carboxypeptidase E | 0.00506783 |
| DSP | desmoplakin | 0.00506648 |
| STX16 | syntaxin 16 | 0.00505932 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00505467 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | 0.00504834 |
| SYCP2 | synaptonemal complex protein 2 | 0.00503355 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00503159 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 0.00503095 |
| PCDH17 | protocadherin 17 | 0.00502055 |
| SLBP | stem-loop binding protein | 0.00502006 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | 0.00500364 |
| CPSF1 | cleavage and polyadenylation specific factor 1, 160kDa | 0.00500191 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.00498132 |
| RAB38 | RAB38, member RAS oncogene family | 0.0049796 |
| PHF10 | PHD finger protein 10 | 0.00497222 |
| CNN3 | calponin 3, acidic | 0.00496181 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | 0.00496073 |
| RANBP6 | RAN binding protein 6 | 0.0049451 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.00493579 |
| AGO3 | argonaute RISC catalytic component 3 | 0.00492774 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.00492421 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.00491667 |
| PMP22 | peripheral myelin protein 22 | 0.00489 |
| MORC2 | MORC family CW-type zinc finger 2 | 0.00488976 |
| ZBTB40 | zinc finger and BTB domain containing 40 | 0.0048894 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00488933 |
| CYC1 | cytochrome c-1 | 0.004867 |
| MPPED2 | metallophosphoesterase domain containing 2 | 0.00486373 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00485982 |
| LMNA | lamin A/C | 0.0048478 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00484277 |
| DPT | dermatopontin | 0.0048392 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.00483861 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 | 0.00481533 |
| NOAZFP | nucleolar atypical zinc finger | 0.00481021 |
| CP | ceruloplasmin (ferroxidase) | 0.00480802 |
| KLHL41 | kelch-like family member 41 | 0.00479997 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00479524 |
| CUL3 | cullin 3 | 0.00479024 |
| KRT14 | keratin 14, type I | 0.00478467 |
| SCEL | sciellin | 0.00476697 |
| GAA | glucosidase, alpha; acid | 0.00475464 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00475392 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.00474843 |
| NKTR | natural killer cell triggering receptor | 0.00474082 |
| COL5A2 | collagen, type V, alpha 2 | 0.00473662 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | 0.00473501 |
| HRASLS | HRAS-like suppressor | 0.00472945 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.00471075 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.00470633 |
| EDNRA | endothelin receptor type A | 0.00469084 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.00467964 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00467745 |
| MBD1 | methyl-CpG binding domain protein 1 | 0.00467684 |
| NFIB | nuclear factor I/B | 0.00466812 |
| PLXDC1 | plexin domain containing 1 | 0.00466726 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.00466725 |
| DENND5A | DENN/MADD domain containing 5A | 0.00466124 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.00465531 |
| SOBP | sine oculis binding protein homolog (Drosophila) | 0.00465104 |
| HELZ | helicase with zinc finger | 0.00464684 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 0.00464083 |
| RPS27L | ribosomal protein S27-like | 0.00463331 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | -0.014409 |
| S100A9 | S100 calcium binding protein A9 | -0.0132385 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.0131962 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -0.0130606 |
| S100A8 | S100 calcium binding protein A8 | -0.0120305 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0120029 |
| MMP12 | matrix metallopeptidase 12 | -0.0116632 |
| LTF | lactotransferrin | -0.0115613 |
| CHEK2 | checkpoint kinase 2 | -0.0115484 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0112233 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0109501 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.010889 |
| TXNIP | thioredoxin interacting protein | -0.0108057 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.0106585 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0105828 |
| S100A7 | S100 calcium binding protein A7 | -0.0101418 |
| GCA | grancalcin, EF-hand calcium binding protein | -0.0100021 |
| KRT19 | keratin 19, type I | -0.00975754 |
| MAL | mal, T-cell differentiation protein | -0.00962496 |
| RHOB | ras homolog family member B | -0.00957563 |
| AOC1 | amine oxidase, copper containing 1 | -0.00945976 |
| CLDN10 | claudin 10 | -0.00923834 |
| GUCY2C | guanylate cyclase 2C | -0.009029 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.00900225 |
| NTS | neurotensin | -0.00882945 |
| SYNGR3 | synaptogyrin 3 | -0.00876176 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0086575 |
| GLUL | glutamate-ammonia ligase | -0.00859571 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) | -0.00857154 |
| OLFM1 | olfactomedin 1 | -0.00856749 |
| LY75 | lymphocyte antigen 75 | -0.00849403 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.00846141 |
| CALB1 | calbindin 1, 28kDa | -0.00839045 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | -0.00823573 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00822027 |
| GLOD4 | glyoxalase domain containing 4 | -0.00813582 |
| SELENBP1 | selenium binding protein 1 | -0.00808487 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.00798706 |
| VNN1 | vanin 1 | -0.00796636 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00789857 |
| TSPAN1 | tetraspanin 1 | -0.00789186 |
| IFITM2 | interferon induced transmembrane protein 2 | -0.00786268 |
| PUDP | pseudouridine 5'-phosphatase | -0.00779914 |
| SPRR3 | small proline-rich protein 3 | -0.00765442 |
| AK4 | adenylate kinase 4 | -0.0076023 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.00756428 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.0075524 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00751168 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00748357 |
| IL2RG | interleukin 2 receptor, gamma | -0.00748209 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | -0.00743126 |
| FABP6 | fatty acid binding protein 6, ileal | -0.00740926 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00737763 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00717435 |
| IL7R | interleukin 7 receptor | -0.00716374 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00715346 |
| SSBP3 | single stranded DNA binding protein 3 | -0.00715049 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.00714917 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -0.00700054 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.00698603 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00696445 |
| HEPH | hephaestin | -0.0069618 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00689076 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.00688704 |
| HIP1 | huntingtin interacting protein 1 | -0.00685265 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00684786 |
| CES1 | carboxylesterase 1 | -0.00681598 |
| RRM2 | ribonucleotide reductase M2 | -0.00680562 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | -0.0067847 |
| RNASE6 | ribonuclease, RNase A family, k6 | -0.0067644 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00676128 |
| ZNF140 | zinc finger protein 140 | -0.00673557 |
| DCXR | dicarbonyl/L-xylulose reductase | -0.00673169 |
| HNMT | histamine N-methyltransferase | -0.00671619 |
| ANGPT1 | angiopoietin 1 | -0.00669027 |
| DMD | dystrophin | -0.00668765 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.00667541 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | -0.00666553 |
| DAZAP2 | DAZ associated protein 2 | -0.00663003 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | -0.00661776 |
| HBB | hemoglobin, beta | -0.00659941 |
| TPD52L1 | tumor protein D52-like 1 | -0.00658723 |
| AGA | aspartylglucosaminidase | -0.00658681 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | -0.00657832 |
| NMRK1 | nicotinamide riboside kinase 1 | -0.00656706 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00656524 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00655867 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.00655627 |
| BMP4 | bone morphogenetic protein 4 | -0.00655477 |
| FAR2 | fatty acyl CoA reductase 2 | -0.0065543 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | -0.00653778 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00652362 |
| AMACR | alpha-methylacyl-CoA racemase | -0.00649281 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00648705 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.00648002 |
| TMEM14A | transmembrane protein 14A | -0.00647254 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -0.00647114 |
| NEFH | neurofilament, heavy polypeptide | -0.00643022 |
| TST | thiosulfate sulfurtransferase (rhodanese) | -0.00638963 |
| IL1R1 | interleukin 1 receptor, type I | -0.00634795 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0063416 |
| NDRG1 | N-myc downstream regulated 1 | -0.00630267 |
| HIST3H2A | histone cluster 3, H2a | -0.00628637 |
| CTSS | cathepsin S | -0.0062814 |
| HCP5 | HLA complex P5 (non-protein coding) | -0.00627124 |
| ADM | adrenomedullin | -0.00626671 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00625646 |
| VSNL1 | visinin-like 1 | -0.00623619 |
| KLK6 | kallikrein-related peptidase 6 | -0.00621813 |
| CDCP1 | CUB domain containing protein 1 | -0.00620313 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.0061863 |
| DACH1 | dachshund family transcription factor 1 | -0.00617429 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -0.00616678 |
| EVI2A | ecotropic viral integration site 2A | -0.00616239 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00612274 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | -0.00610611 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.00608941 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00607726 |
| ZNF423 | zinc finger protein 423 | -0.00605266 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.0060486 |
| OLFM4 | olfactomedin 4 | -0.00604736 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.00603727 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00600431 |
| GPX2 | glutathione peroxidase 2 | -0.00599541 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.00598898 |
| CRYL1 | crystallin, lambda 1 | -0.00596426 |
| S100A12 | S100 calcium binding protein A12 | -0.00595582 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.00595364 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00595341 |
| LYZ | lysozyme | -0.00593012 |
| CYTIP | cytohesin 1 interacting protein | -0.00589782 |
| IL1R2 | interleukin 1 receptor, type II | -0.00589297 |
| LIMA1 | LIM domain and actin binding 1 | -0.00588299 |
| VIPR1 | vasoactive intestinal peptide receptor 1 | -0.00588264 |
| RNASET2 | ribonuclease T2 | -0.005878 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.00587593 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.0058569 |
| PTHLH | parathyroid hormone-like hormone | -0.00585522 |
| ANXA1 | annexin A1 | -0.00583177 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00582923 |
| MMD | monocyte to macrophage differentiation-associated | -0.00581433 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.00581029 |
| ALPL | alkaline phosphatase, liver/bone/kidney | -0.00574292 |
| EFNA1 | ephrin-A1 | -0.00573643 |
| NELL2 | NEL-like 2 (chicken) | -0.00573387 |
| TP53 | tumor protein p53 | -0.00568116 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.00567775 |
| RTN2 | reticulon 2 | -0.00566133 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.00566128 |
| ACVR1B | activin A receptor, type IB | -0.00563591 |
| IRF6 | interferon regulatory factor 6 | -0.0056199 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00561511 |
| CRYM | crystallin, mu | -0.00560378 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.00559318 |
| MCOLN1 | mucolipin 1 | -0.00555575 |
| PROM1 | prominin 1 | -0.00554005 |
| TFF1 | trefoil factor 1 | -0.00552638 |
| BTNL8 | butyrophilin-like 8 | -0.0055206 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | -0.00551896 |
| TMEM176A | transmembrane protein 176A | -0.00550979 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.00549612 |
| ABHD10 | abhydrolase domain containing 10 | -0.00549354 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.00548737 |
| HLA-DOB | major histocompatibility complex, class II, DO beta | -0.00545503 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.00545482 |
| TBC1D15 | TBC1 domain family, member 15 | -0.0054416 |
| JPT2 | Jupiter microtubule associated homolog 2 | -0.00544024 |
| ADD3 | adducin 3 (gamma) | -0.00542265 |
| METTL9 | methyltransferase like 9 | -0.00540478 |
| TRIM68 | tripartite motif containing 68 | -0.0053944 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00539391 |
| PCTP | phosphatidylcholine transfer protein | -0.00538374 |
| MED7 | mediator complex subunit 7 | -0.00538115 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | -0.00537476 |
| S100P | S100 calcium binding protein P | -0.00537159 |
| GPR137B | G protein-coupled receptor 137B | -0.00537091 |
| OSMR | oncostatin M receptor | -0.00536383 |
| YPEL5 | yippee-like 5 (Drosophila) | -0.00536328 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | -0.00535805 |
| RESF1 | retroelement silencing factor 1 | -0.00533518 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | -0.00533465 |
| ERLIN2 | ER lipid raft associated 2 | -0.00532414 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.00531616 |
| FYB1 | FYN binding protein 1 | -0.00530962 |
| CPQ | carboxypeptidase Q | -0.00530488 |
| DENND1B | DENN/MADD domain containing 1B | -0.005304 |
| CORO1C | coronin, actin binding protein, 1C | -0.00529348 |
| CALML4 | calmodulin-like 4 | -0.00528772 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.0052806 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00527159 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00526174 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.00525791 |
| SOSTDC1 | sclerostin domain containing 1 | -0.00524894 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00522577 |
| LDLRAP1 | low density lipoprotein receptor adaptor protein 1 | -0.00520639 |
| FPR1 | formyl peptide receptor 1 | -0.0052034 |
| CD48 | CD48 molecule | -0.00519563 |
| IGBP1 | immunoglobulin (CD79A) binding protein 1 | -0.0051947 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00518603 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 | -0.00516966 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00515715 |
| LEPR | leptin receptor | -0.00515645 |
| ASRGL1 | asparaginase like 1 | -0.00513936 |
| STAT5A | signal transducer and activator of transcription 5A | -0.00513531 |
| PCYOX1 | prenylcysteine oxidase 1 | -0.00512863 |
| GSTK1 | glutathione S-transferase kappa 1 | -0.00512624 |
| ZNF468 | zinc finger protein 468 | -0.00511649 |
| PQBP1 | polyglutamine binding protein 1 | -0.0051019 |
| SNX11 | sorting nexin 11 | -0.00510037 |
| BPGM | 2,3-bisphosphoglycerate mutase | -0.00509921 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00508351 |
| MGST3 | microsomal glutathione S-transferase 3 | -0.00507106 |
| RWDD3 | RWD domain containing 3 | -0.00506848 |
| SLA | Src-like-adaptor | -0.0050684 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00506488 |
| FZD10 | frizzled class receptor 10 | -0.00506191 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00503995 |
| ADAP1 | ArfGAP with dual PH domains 1 | -0.0050362 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.00503457 |
| CDC42 | cell division cycle 42 | -0.00501965 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | -0.0050181 |
| BCL2L14 | BCL2-like 14 (apoptosis facilitator) | -0.00498895 |
| ATG5 | autophagy related 5 | -0.00498684 |
| CD1B | CD1b molecule | -0.00498053 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | -0.00497983 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00497814 |
| BIN1 | bridging integrator 1 | -0.00497573 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00497463 |
| PIR | pirin (iron-binding nuclear protein) | -0.00497409 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00496659 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.00496279 |
| NIT2 | nitrilase family, member 2 | -0.00495592 |
| YIPF5 | Yip1 domain family, member 5 | -0.00494495 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 | -0.00493955 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00493742 |
| DMBT1 | deleted in malignant brain tumors 1 | -0.0049372 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00493195 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00493029 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.00492956 |
| PENK | proenkephalin | -0.00492802 |
| IL7 | interleukin 7 | -0.00492055 |
| GIPC2 | GIPC PDZ domain containing family, member 2 | -0.00491886 |
| SRGN | serglycin | -0.00491119 |
| LY96 | lymphocyte antigen 96 | -0.00490806 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | -0.00489867 |
| SYNGR2 | synaptogyrin 2 | -0.00489463 |
| MPO | myeloperoxidase | -0.00489286 |
| AZIN1 | antizyme inhibitor 1 | -0.0048821 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | -0.00487331 |
