RBPJ Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description recombination signal binding protein for immunoglobulin kappa J region|The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2013] (NCBI Entrez Gene Database, 3516)
External Link http://www.ncbi.nlm.nih.gov/gene/3516
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128 interacting proteins for RBPJ from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ACTG1 actin gamma 1
ADIPOR1 adiponectin receptor 1
ADNP activity-dependent neuroprotector homeobox
AFAP1 actin filament associated protein 1
AKAP8 A kinase (PRKA) anchor protein 8
ANXA2 annexin A2
APP amyloid beta (A4) precursor protein
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
ATXN1 ataxin 1
ATXN1L ataxin 1-like
BCL6B B-cell CLL/lymphoma 6, member B
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK4 calcium/calmodulin-dependent protein kinase IV
CBFB core-binding factor, beta subunit
CDYL chromodomain protein, Y-like
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CIR1 corepressor interacting with RBPJ, 1
CKAP4 cytoskeleton-associated protein 4
CTNND1 catenin (cadherin-associated protein), delta 1
CTPS1 CTP synthase 1
CYC1 cytochrome c-1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DLK1 delta-like 1 homolog (Drosophila)
DLL1 delta-like 1 (Drosophila)
DLL3 delta-like 3 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
ECSIT ECSIT signalling integrator
EEF1G eukaryotic translation elongation factor 1 gamma
ELAVL1 ELAV like RNA binding protein 1
EP400 E1A binding protein p400
ERBB2IP erbb2 interacting protein
ERC1 ELKS/RAB6-interacting/CAST family member 1
ETV3 ets variant 3
F2R coagulation factor II (thrombin) receptor
FHL1 four and a half LIM domains 1
FHL2 four and a half LIM domains 2
FLNA filamin A, alpha
FN1 fibronectin 1
FOSL1 FOS-like antigen 1
FOXP1 forkhead box P1
GADD45A growth arrest and DNA-damage-inducible, alpha
GANAB glucosidase, alpha; neutral AB
GSK3B glycogen synthase kinase 3 beta
HDAC1 histone deacetylase 1
HDAC3 histone deacetylase 3
HMGB1 high mobility group box 1
HSPA1B heat shock 70kDa protein 1B
HSPB1 heat shock 27kDa protein 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
JAG1 jagged 1
JAG2 jagged 2
KAT2A K(lysine) acetyltransferase 2A
KAT2B K(lysine) acetyltransferase 2B
KAT5 K(lysine) acetyltransferase 5
KDM1A lysine (K)-specific demethylase 1A
KDM5A lysine (K)-specific demethylase 5A
LGALS1 lectin, galactoside-binding, soluble, 1
LMNA lamin A/C
MAML1 mastermind-like 1 (Drosophila)
MAX MYC associated factor X
MECP2 methyl CpG binding protein 2
MED27 mediator complex subunit 27
MRPL53 mitochondrial ribosomal protein L53
MYC v-myc avian myelocytomatosis viral oncogene homolog
MZT2B mitotic spindle organizing protein 2B
NABP2 nucleic acid binding protein 2
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NONO non-POU domain containing, octamer-binding
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NOTCH4 notch 4
NUP93 nucleoporin 93kDa
OPA1 optic atrophy 1 (autosomal dominant)
P3H1 prolyl 3-hydroxylase 1
PDLIM7 PDZ and LIM domain 7 (enigma)
PHF8 PHD finger protein 8
PHLDB2 pleckstrin homology-like domain, family B, member 2
PRKCDBP protein kinase C, delta binding protein
PRPF6 pre-mRNA processing factor 6
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTRF polymerase I and transcript release factor
QPCTL glutaminyl-peptide cyclotransferase-like
RARS arginyl-tRNA synthetase
RBMS2 RNA binding motif, single stranded interacting protein 2
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RFC4 replication factor C (activator 1) 4, 37kDa
RIF1 replication timing regulatory factor 1
RNF130 ring finger protein 130
RPL13 ribosomal protein L13
RPS27L ribosomal protein S27-like
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
RUNX3 runt-related transcription factor 3
SDF2L1 stromal cell-derived factor 2-like 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SH3BP4 SH3-domain binding protein 4
SIN3A SIN3 transcription regulator family member A
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMC4 structural maintenance of chromosomes 4
SMTN smoothelin
SND1 staphylococcal nuclease and tudor domain containing 1
SNW1 SNW domain containing 1
SPEN spen family transcriptional repressor
SRP9 signal recognition particle 9kDa
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SSR1 signal sequence receptor, alpha
SUFU suppressor of fused homolog (Drosophila)
TCF12 transcription factor 12
TF transferrin
TFAM transcription factor A, mitochondrial
TKT transketolase
TP53 tumor protein p53
TRIM21 tripartite motif containing 21
TSN translin
TUBA4A tubulin, alpha 4a
TXN thioredoxin
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
YBX1 Y box binding protein 1