| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/RB_P130_DN.V1_UP |
| Similar Terms | |
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272 genes differentially expressed following the RB_P130_DN.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| ADCK3 | aarF domain containing kinase 3 |
| ALK | anaplastic lymphoma receptor tyrosine kinase |
| ANAPC5 | anaphase promoting complex subunit 5 |
| AQP5 | aquaporin 5 |
| ART1 | ADP-ribosyltransferase 1 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| AURKA | aurora kinase A |
| AURKB | aurora kinase B |
| AVP | arginine vasopressin |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 |
| BIRC5 | baculoviral IAP repeat containing 5 |
| C11ORF31 | chromosome 11 open reading frame 31 |
| C11ORF71 | chromosome 11 open reading frame 71 |
| C12ORF10 | chromosome 12 open reading frame 10 |
| C9ORF89 | chromosome 9 open reading frame 89 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCNB2 | cyclin B2 |
| CDC7 | cell division cycle 7 |
| CDK1 | cyclin-dependent kinase 1 |
| CHCHD6 | coiled-coil-helix-coiled-coil-helix domain containing 6 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CMTM7 | CKLF-like MARVEL transmembrane domain containing 7 |
| COL11A2 | collagen, type XI, alpha 2 |
| CRB3 | crumbs family member 3 |
| CRLF1 | cytokine receptor-like factor 1 |
| CRTAC1 | cartilage acidic protein 1 |
| CUEDC2 | CUE domain containing 2 |
| CYBA | cytochrome b-245, alpha polypeptide |
| DCTPP1 | dCTP pyrophosphatase 1 |
| DUSP13 | dual specificity phosphatase 13 |
| EFTUD2 | elongation factor Tu GTP binding domain containing 2 |
| EIF1B | eukaryotic translation initiation factor 1B |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) |
| ENKD1 | enkurin domain containing 1 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog |
| EXOSC2 | exosome component 2 |
| FADS2 | fatty acid desaturase 2 |
| FAM187A | family with sequence similarity 187, member A |
| FAM220A | family with sequence similarity 220, member A |
| FAM64A | family with sequence similarity 64, member A |
| FAM73B | family with sequence similarity 73, member B |
| FGF10 | fibroblast growth factor 10 |
| FOXI1 | forkhead box I1 |
| FST | follistatin |
| GC | group-specific component (vitamin D binding protein) |
| GFER | growth factor, augmenter of liver regeneration |
| GLIS2 | GLIS family zinc finger 2 |
| GPN3 | GPN-loop GTPase 3 |
| GREM2 | gremlin 2, DAN family BMP antagonist |
| GRTP1 | growth hormone regulated TBC protein 1 |
| H2AFB1 | H2A histone family, member B1 |
| HINT1 | histidine triad nucleotide binding protein 1 |
| HMGA2 | high mobility group AT-hook 2 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IER3 | immediate early response 3 |
| KAZN | kazrin, periplakin interacting protein |
| KIF20A | kinesin family member 20A |
| KIF22 | kinesin family member 22 |
| LITAF | lipopolysaccharide-induced TNF factor |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MBD3 | methyl-CpG binding domain protein 3 |
| MRAS | muscle RAS oncogene homolog |
| MYLK | myosin light chain kinase |
| MYOZ2 | myozenin 2 |
| NKD2 | naked cuticle homolog 2 (Drosophila) |
| NKX2-8 | NK2 homeobox 8 |
| NPPB | natriuretic peptide B |
| NSMCE1 | non-SMC element 1 homolog (S. cerevisiae) |
| NXNL1 | nucleoredoxin-like 1 |
| OAF | OAF homolog (Drosophila) |
| ORC1 | origin recognition complex, subunit 1 |
| OXLD1 | oxidoreductase-like domain containing 1 |
| PARS2 | prolyl-tRNA synthetase 2, mitochondrial (putative) |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 |
| PDZK1 | PDZ domain containing 1 |
| PF4 | platelet factor 4 |
| PIWIL1 | piwi-like RNA-mediated gene silencing 1 |
| POLD2 | polymerase (DNA directed), delta 2, accessory subunit |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RABEPK | Rab9 effector protein with kelch motifs |
| RACGAP1 | Rac GTPase activating protein 1 |
| RAD51D | RAD51 paralog D |
| RASA4 | RAS p21 protein activator 4 |
| RASD1 | RAS, dexamethasone-induced 1 |
| RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 |
| RENBP | renin binding protein |
| RGL3 | ral guanine nucleotide dissociation stimulator-like 3 |
| RGS16 | regulator of G-protein signaling 16 |
| RHOJ | ras homolog family member J |
| RIPK3 | receptor-interacting serine-threonine kinase 3 |
| RSPH9 | radial spoke head 9 homolog (Chlamydomonas) |
| RUVBL2 | RuvB-like AAA ATPase 2 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEMA5B | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SGSM3 | small G protein signaling modulator 3 |
| SIM1 | single-minded family bHLH transcription factor 1 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC13A2 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| SLC43A3 | solute carrier family 43, member 3 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SNN | stannin |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 |
| SNRPC | small nuclear ribonucleoprotein polypeptide C |
| SNTA1 | syntrophin, alpha 1 |
| SPATA13 | spermatogenesis associated 13 |
| STAT5B | signal transducer and activator of transcription 5B |
| STMN3 | stathmin-like 3 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAL2 | T-cell acute lymphocytic leukemia 2 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TINAG | tubulointerstitial nephritis antigen |
| TK1 | thymidine kinase 1, soluble |
| TMEM151B | transmembrane protein 151B |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAF4 | TNF receptor-associated factor 4 |
| TWIST2 | twist family bHLH transcription factor 2 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) |
| VSIG2 | V-set and immunoglobulin domain containing 2 |
| WNT2B | wingless-type MMTV integration site family, member 2B |
| ZBTB12 | zinc finger and BTB domain containing 12 |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZNF428 | zinc finger protein 428 |
| Symbol | Name |
|---|---|
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| AKAP9 | A kinase (PRKA) anchor protein 9 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARRDC4 | arrestin domain containing 4 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATAD1 | ATPase family, AAA domain containing 1 |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 |
| ATP9B | ATPase, class II, type 9B |
| AVL9 | AVL9 homolog (S. cerevisiase) |
| B2M | beta-2-microglobulin |
| BNC1 | basonuclin 1 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| C10ORF99 | chromosome 10 open reading frame 99 |
| C17ORF62 | chromosome 17 open reading frame 62 |
| C3ORF70 | chromosome 3 open reading frame 70 |
| C9ORF72 | chromosome 9 open reading frame 72 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 |
| CASP6 | caspase 6, apoptosis-related cysteine peptidase |
| CD1D | CD1d molecule |
| CHMP1B | charged multivesicular body protein 1B |
| CLIP1 | CAP-GLY domain containing linker protein 1 |
| CLU | clusterin |
| COPB1 | coatomer protein complex, subunit beta 1 |
| CSDE1 | cold shock domain containing E1, RNA-binding |
| CTSB | cathepsin B |
| CTSC | cathepsin C |
| CTSK | cathepsin K |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 |
| DEFB1 | defensin, beta 1 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 |
| DSP | desmoplakin |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 |
| EBPL | emopamil binding protein-like |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| EIF3J | eukaryotic translation initiation factor 3, subunit J |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) |
| EVI5 | ecotropic viral integration site 5 |
| FAM214B | family with sequence similarity 214, member B |
| FAM32A | family with sequence similarity 32, member A |
| FBXO28 | F-box protein 28 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GAS5 | growth arrest-specific 5 (non-protein coding) |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GJB2 | gap junction protein, beta 2, 26kDa |
| GLO1 | glyoxalase I |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 |
| GNS | glucosamine (N-acetyl)-6-sulfatase |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) |
| GUCA2A | guanylate cyclase activator 2A (guanylin) |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
| HK2 | hexokinase 2 |
| HLA-G | major histocompatibility complex, class I, G |
| HSPA1B | heat shock 70kDa protein 1B |
| HTRA1 | HtrA serine peptidase 1 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IFITM10 | interferon induced transmembrane protein 10 |
| KDM5B | lysine (K)-specific demethylase 5B |
| KIAA1161 | KIAA1161 |
| KIF16B | kinesin family member 16B |
| KLK6 | kallikrein-related peptidase 6 |
| KLK7 | kallikrein-related peptidase 7 |
| KRT1 | keratin 1, type II |
| KRT10 | keratin 10, type I |
| KRT6B | keratin 6B, type II |
| KRT79 | keratin 79, type II |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LAMP2 | lysosomal-associated membrane protein 2 |
| LGALSL | lectin, galactoside-binding-like |
| LIFR | leukemia inhibitory factor receptor alpha |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| MFN1 | mitofusin 1 |
| MORC3 | MORC family CW-type zinc finger 3 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NCL | nucleolin |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NRARP | NOTCH-regulated ankyrin repeat protein |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 |
| PCDHB17P | protocadherin beta 17 pseudogene |
| PLBD1 | phospholipase B domain containing 1 |
| PNRC2 | proline-rich nuclear receptor coactivator 2 |
| PRPF38B | pre-mRNA processing factor 38B |
| PVRL4 | poliovirus receptor-related 4 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 |
| RAB24 | RAB24, member RAS oncogene family |
| RAB8B | RAB8B, member RAS oncogene family |
| RAP2C | RAP2C, member of RAS oncogene family |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 |
| RB1 | retinoblastoma 1 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RHOV | ras homolog family member V |
| RNASET2 | ribonuclease T2 |
| RRAGA | Ras-related GTP binding A |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCEL | sciellin |
| SEC23A | Sec23 homolog A (S. cerevisiae) |
| SEC24C | SEC24 family member C |
| SELK | selenoprotein K |
| SH3BP5L | SH3-binding domain protein 5-like |
| SLC10A6 | solute carrier family 10 (sodium/bile acid cotransporter), member 6 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC35F6 | solute carrier family 35, member F6 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMIM14 | small integral membrane protein 14 |
| SNX2 | sorting nexin 2 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) |
| SPOP | speckle-type POZ protein |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| TFB2M | transcription factor B2, mitochondrial |
| TMEM123 | transmembrane protein 123 |
| TMEM140 | transmembrane protein 140 |
| TMEM87A | transmembrane protein 87A |
| TOMM34 | translocase of outer mitochondrial membrane 34 |
| TXLNG | taxilin gamma |
| TXNDC9 | thioredoxin domain containing 9 |
| TYW5 | tRNA-yW synthesizing protein 5 |
| UBXN4 | UBX domain protein 4 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| USP18 | ubiquitin specific peptidase 18 |
| USP47 | ubiquitin specific peptidase 47 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 |
| WDR26 | WD repeat domain 26 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 |
| ZMPSTE24 | zinc metallopeptidase STE24 |
