RCC-JF Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description cell line derived from kidney (Catalogue of Somatic Mutations In Cancer)
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Genes

324 genes mutated in the RCC-JF cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACAN aggrecan
ACSS1 acyl-CoA synthetase short-chain family member 1
ADAM33 ADAM metallopeptidase domain 33
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
ADAMTSL1 ADAMTS-like 1
ADGRL3 adhesion G protein-coupled receptor L3
ADIG adipogenin
ADRA1A adrenoceptor alpha 1A
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AGFG2 ArfGAP with FG repeats 2
AKAP12 A kinase (PRKA) anchor protein 12
AKAP7 A kinase (PRKA) anchor protein 7
AKAP9 A kinase (PRKA) anchor protein 9
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
AMICA1 adhesion molecule, interacts with CXADR antigen 1
ANKLE1 ankyrin repeat and LEM domain containing 1
ANKRD36C ankyrin repeat domain 36C
ANO7 anoctamin 7
ANPEP alanyl (membrane) aminopeptidase
APRT adenine phosphoribosyltransferase
ARHGAP35 Rho GTPase activating protein 35
ASCC3 activating signal cointegrator 1 complex subunit 3
ATP13A3 ATPase type 13A3
BBS2 Bardet-Biedl syndrome 2
BBS4 Bardet-Biedl syndrome 4
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BOD1L1 biorientation of chromosomes in cell division 1-like 1
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CARD6 caspase recruitment domain family, member 6
CASC5 cancer susceptibility candidate 5
CCDC43 coiled-coil domain containing 43
CCR10 chemokine (C-C motif) receptor 10
CD177 CD177 molecule
CDCA7L cell division cycle associated 7-like
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CELF6 CUGBP, Elav-like family member 6
CFLAR CASP8 and FADD-like apoptosis regulator
CGREF1 cell growth regulator with EF-hand domain 1
CHD6 chromodomain helicase DNA binding protein 6
CHEK2 checkpoint kinase 2
CLASP2 cytoplasmic linker associated protein 2
CLCN6 chloride channel, voltage-sensitive 6
CLDN18 claudin 18
CMKLR1 chemerin chemokine-like receptor 1
CNGA2 cyclic nucleotide gated channel alpha 2
CNTNAP3B contactin associated protein-like 3B
CNTNAP4 contactin associated protein-like 4
CREBBP CREB binding protein
CRELD1 cysteine-rich with EGF-like domains 1
CRHR1 corticotropin releasing hormone receptor 1
CROCC ciliary rootlet coiled-coil, rootletin
CSMD1 CUB and Sushi multiple domains 1
CSMD3 CUB and Sushi multiple domains 3
CSPG4 chondroitin sulfate proteoglycan 4
CTAGE5 CTAGE family, member 5
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
DAAM2 dishevelled associated activator of morphogenesis 2
DCBLD2 discoidin, CUB and LCCL domain containing 2
DCLRE1B DNA cross-link repair 1B
DDR1 discoidin domain receptor tyrosine kinase 1
DGKQ diacylglycerol kinase, theta 110kDa
DHRS7C dehydrogenase/reductase (SDR family) member 7C
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DNAH6 dynein, axonemal, heavy chain 6
DNAH7 dynein, axonemal, heavy chain 7
DNAH9 dynein, axonemal, heavy chain 9
DNAI2 dynein, axonemal, intermediate chain 2
DOCK3 dedicator of cytokinesis 3
DOCK9 dedicator of cytokinesis 9
DPP10 dipeptidyl-peptidase 10 (non-functional)
DTD1 D-tyrosyl-tRNA deacylase 1
DUS3L dihydrouridine synthase 3-like (S. cerevisiae)
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
EFCAB6 EF-hand calcium binding domain 6
EGR4 early growth response 4
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ELSPBP1 epididymal sperm binding protein 1
ENOPH1 enolase-phosphatase 1
EP400 E1A binding protein p400
EPB42 erythrocyte membrane protein band 4.2
EPHA4 EPH receptor A4
ERCC6L excision repair cross-complementation group 6-like
ERGIC3 ERGIC and golgi 3
FAT3 FAT atypical cadherin 3
FAT4 FAT atypical cadherin 4
FGFR3 fibroblast growth factor receptor 3
FGR FGR proto-oncogene, Src family tyrosine kinase
FHOD3 formin homology 2 domain containing 3
FLG filaggrin
FNTB farnesyltransferase, CAAX box, beta
FRAS1 Fraser extracellular matrix complex subunit 1
FRG2C FSHD region gene 2 family, member C
FSD1L fibronectin type III and SPRY domain containing 1-like
FTH1P19 ferritin, heavy polypeptide 1 pseudogene 19
GAS2 growth arrest-specific 2
GEMIN4 gem (nuclear organelle) associated protein 4
GIMAP8 GTPase, IMAP family member 8
GJC2 gap junction protein, gamma 2, 47kDa
GK glycerol kinase
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GOLGB1 golgin B1
GPR146 G protein-coupled receptor 146
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTA2 glutathione S-transferase alpha 2
HAPLN3 hyaluronan and proteoglycan link protein 3
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
HHAT hedgehog acyltransferase
HIST1H4I histone cluster 1, H4i
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-B major histocompatibility complex, class I, B
HSF2 heat shock transcription factor 2
HSPH1 heat shock 105kDa/110kDa protein 1
HTRA2 HtrA serine peptidase 2
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B
IL1RAP interleukin 1 receptor accessory protein
IL6ST interleukin 6 signal transducer
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INTS8 integrator complex subunit 8
ITGA10 integrin, alpha 10
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13
KCTD7 potassium channel tetramerization domain containing 7
KIF25 kinesin family member 25
KLHL31 kelch-like family member 31
KRT13 keratin 13, type I
KRT23 keratin 23, type I
KSR2 kinase suppressor of ras 2
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAPTM4B lysosomal protein transmembrane 4 beta
LOXHD1 lipoxygenase homology domains 1
LRP5 low density lipoprotein receptor-related protein 5
LRRC8E leucine rich repeat containing 8 family, member E
LRRD1 leucine-rich repeats and death domain containing 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAK16 MAK16 homolog (S. cerevisiae)
MBNL3 muscleblind-like splicing regulator 3
MCC mutated in colorectal cancers
MCM2 minichromosome maintenance complex component 2
MCTP1 multiple C2 domains, transmembrane 1
MDFI MyoD family inhibitor
MED13 mediator complex subunit 13
METTL5 methyltransferase like 5
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MPP1 membrane protein, palmitoylated 1, 55kDa
MROH2A maestro heat-like repeat family member 2A
MROH7 maestro heat-like repeat family member 7
MSLN mesothelin
MTMR3 myotubularin related protein 3
MUC16 mucin 16, cell surface associated
MUC17 mucin 17, cell surface associated
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MXRA5 matrix-remodelling associated 5
MYO18A myosin XVIIIA
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
N4BP3 NEDD4 binding protein 3
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NCAPD3 non-SMC condensin II complex, subunit D3
NCOR2 nuclear receptor corepressor 2
NPHP4 nephronophthisis 4
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NRROS negative regulator of reactive oxygen species
NSD1 nuclear receptor binding SET domain protein 1
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5
NUP160 nucleoporin 160kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OLFML2B olfactomedin-like 2B
OR1L6 olfactory receptor, family 1, subfamily L, member 6
OR4K15 olfactory receptor, family 4, subfamily K, member 15
OR51J1 olfactory receptor, family 51, subfamily J, member 1 (gene/pseudogene)
OR8H3 olfactory receptor, family 8, subfamily H, member 3
OR8I2 olfactory receptor, family 8, subfamily I, member 2
OSGIN1 oxidative stress induced growth inhibitor 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
OXTR oxytocin receptor
PARP4 poly (ADP-ribose) polymerase family, member 4
PASK PAS domain containing serine/threonine kinase
PCDHA1 protocadherin alpha 1
PCDHA10 protocadherin alpha 10
PCDHA11 protocadherin alpha 11
PCDHA12 protocadherin alpha 12
PCDHA13 protocadherin alpha 13
PCDHA2 protocadherin alpha 2
PCDHA3 protocadherin alpha 3
PCDHA4 protocadherin alpha 4
PCDHA5 protocadherin alpha 5
PCDHA6 protocadherin alpha 6
PCDHA7 protocadherin alpha 7
PCDHA8 protocadherin alpha 8
PCDHA9 protocadherin alpha 9
PCDHAC1 protocadherin alpha subfamily C, 1
PCDHAC2 protocadherin alpha subfamily C, 2
PCDHB10 protocadherin beta 10
PCM1 pericentriolar material 1
PDIA4 protein disulfide isomerase family A, member 4
PEAR1 platelet endothelial aggregation receptor 1
PF4 platelet factor 4
PGLYRP3 peptidoglycan recognition protein 3
PHF20L1 PHD finger protein 20-like 1
PHF21A PHD finger protein 21A
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLA2R1 phospholipase A2 receptor 1, 180kDa
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
PLG plasminogen
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POM121L2 POM121 transmembrane nucleoporin-like 2
POTEJ POTE ankyrin domain family, member J
POU2F1 POU class 2 homeobox 1
PPAPDC3 phosphatidic acid phosphatase type 2 domain containing 3
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PRAP1 proline-rich acidic protein 1
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PROM2 prominin 2
PROX2 prospero homeobox 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAB18 RAB18, member RAS oncogene family
RAB2A RAB2A, member RAS oncogene family
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASAL1 RAS protein activator like 1 (GAP1 like)
REPIN1 replication initiator 1
RGPD3 RANBP2-like and GRIP domain containing 3
RNF13 ring finger protein 13
RNF151 ring finger protein 151
RNF213 ring finger protein 213
RNF43 ring finger protein 43
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
SACK1B scaffolding CK1 anchoring protein B
SETD2 SET domain containing 2
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SGOL1 shugoshin-like 1 (S. pombe)
SH2D3C SH2 domain containing 3C
SH3BP2 SH3-domain binding protein 2
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC2A14 solute carrier family 2 (facilitated glucose transporter), member 14
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SNX24 sorting nexin 24
SOX7 SRY (sex determining region Y)-box 7
SPATA6L spermatogenesis associated 6-like
SPATS2 spermatogenesis associated, serine-rich 2
SRBD1 S1 RNA binding domain 1
SRP72 signal recognition particle 72kDa
SRPR signal recognition particle receptor (docking protein)
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST7 suppression of tumorigenicity 7
STIM1 stromal interaction molecule 1
STK11 serine/threonine kinase 11
SV2B synaptic vesicle glycoprotein 2B
SYNE1 spectrin repeat containing, nuclear envelope 1
SYNE3 spectrin repeat containing, nuclear envelope family member 3
SYT2 synaptotagmin II
SYTL2 synaptotagmin-like 2
SYTL3 synaptotagmin-like 3
TADA2A transcriptional adaptor 2A
TANGO6 transport and golgi organization 6 homolog (Drosophila)
TBC1D23 TBC1 domain family, member 23
TCF25 transcription factor 25 (basic helix-loop-helix)
TCF4 transcription factor 4
TDH L-threonine dehydrogenase (pseudogene)
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TG thyroglobulin
THUMPD1 THUMP domain containing 1
TMEM132A transmembrane protein 132A
TMEM92 transmembrane protein 92
TMX3 thioredoxin-related transmembrane protein 3
TNC tenascin C
TNFRSF19 tumor necrosis factor receptor superfamily, member 19
TNN tenascin N
TNS3 tensin 3
TPCN1 two pore segment channel 1
TRIM23 tripartite motif containing 23
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC22D1 TSC22 domain family, member 1
TTC31 tetratricopeptide repeat domain 31
TTLL9 tubulin tyrosine ligase-like family member 9
TTN titin
TUBA1C tubulin, alpha 1c
UBR4 ubiquitin protein ligase E3 component n-recognin 4
USH2A Usher syndrome 2A (autosomal recessive, mild)
USP2 ubiquitin specific peptidase 2
USP42 ubiquitin specific peptidase 42
UTRN utrophin
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WT1-AS WT1 antisense RNA
WWC2 WW and C2 domain containing 2
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
ZBBX zinc finger, B-box domain containing
ZBTB16 zinc finger and BTB domain containing 16
ZBTB4 zinc finger and BTB domain containing 4
ZC3H13 zinc finger CCCH-type containing 13
ZKSCAN2 zinc finger with KRAB and SCAN domains 2
ZMYND11 zinc finger, MYND-type containing 11
ZNF253 zinc finger protein 253
ZNF280C zinc finger protein 280C
ZNF395 zinc finger protein 395
ZNF493 zinc finger protein 493
ZNF512B zinc finger protein 512B
ZNF536 zinc finger protein 536
ZNF609 zinc finger protein 609
ZNF705G zinc finger protein 705G