RCC-MF Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description cell line derived from kidney (Catalogue of Somatic Mutations In Cancer)
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Genes

268 genes mutated in the RCC-MF cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
ABRACL ABRA C-terminal like
ACACB acetyl-CoA carboxylase beta
ACCSL 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
AKAP6 A kinase (PRKA) anchor protein 6
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ALS2CR11 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11
AMDHD2 amidohydrolase domain containing 2
ANKRD30B ankyrin repeat domain 30B
ANKRD36C ankyrin repeat domain 36C
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASB15 ankyrin repeat and SOCS box containing 15
ASTN1 astrotactin 1
ATN1 atrophin 1
ATXN7L3 ataxin 7-like 3
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2
BAIAP2L2 BAI1-associated protein 2-like 2
BARX1 BARX homeobox 1
BCAN brevican
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like
BEGAIN brain-enriched guanylate kinase-associated
BICD2 bicaudal D homolog 2 (Drosophila)
BMP5 bone morphogenetic protein 5
BNC2 basonuclin 2
BRD8 bromodomain containing 8
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C2 complement component 2
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CAMKMT calmodulin-lysine N-methyltransferase
CARD9 caspase recruitment domain family, member 9
CASC4 cancer susceptibility candidate 4
CATSPERG catsper channel auxiliary subunit gamma
CC2D2A coiled-coil and C2 domain containing 2A
CCDC108 coiled-coil domain containing 108
CD101 CD101 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEP290 centrosomal protein 290kDa
CHIT1 chitinase 1 (chitotriosidase)
COL27A1 collagen, type XXVII, alpha 1
COL6A3 collagen, type VI, alpha 3
CPPED1 calcineurin-like phosphoesterase domain containing 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRTC1 CREB regulated transcription coactivator 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DAW1 dynein assembly factor with WDR repeat domains 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29
DIDO1 death inducer-obliterator 1
DISP1 dispatched homolog 1 (Drosophila)
DNAH1 dynein, axonemal, heavy chain 1
DNAH14 dynein, axonemal, heavy chain 14
DOCK7 dedicator of cytokinesis 7
DPYSL3 dihydropyrimidinase-like 3
E4F1 E4F transcription factor 1
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
EMD emerin
ERICH1 glutamate-rich 1
EVI2B ecotropic viral integration site 2B
EXTL3 exostosin-like glycosyltransferase 3
EYS eyes shut homolog (Drosophila)
EZR ezrin
FAM101A family with sequence similarity 101, member A
FAM167A family with sequence similarity 167, member A
FAM167B family with sequence similarity 167, member B
FASTKD5 FAST kinase domains 5
FBLN2 fibulin 2
FCRL1 Fc receptor-like 1
FKBP5 FK506 binding protein 5
FLYWCH1 FLYWCH-type zinc finger 1
FMNL3 formin-like 3
FN1 fibronectin 1
FSD2 fibronectin type III and SPRY domain containing 2
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2
GAS2L3 growth arrest-specific 2 like 3
GGT2 gamma-glutamyltransferase 2
GHDC GH3 domain containing
GIGYF1 GRB10 interacting GYF protein 1
GLYAT glycine-N-acyltransferase
GPR137 G protein-coupled receptor 137
GPR61 G protein-coupled receptor 61
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
HGFAC HGF activator
HIST1H1D histone cluster 1, H1d
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
HLA-A major histocompatibility complex, class I, A
HLA-C major histocompatibility complex, class I, C
HPCAL1 hippocalcin-like 1
HYDIN HYDIN, axonemal central pair apparatus protein
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
INPP5J inositol polyphosphate-5-phosphatase J
ITPKC inositol-trisphosphate 3-kinase C
JMJD8 jumonji domain containing 8
KBTBD6 kelch repeat and BTB (POZ) domain containing 6
KDM8 lysine (K)-specific demethylase 8
KDR kinase insert domain receptor
KIAA0754 KIAA0754
KIAA1671 KIAA1671
KIF17 kinesin family member 17
KIF18B kinesin family member 18B
KIF3A kinesin family member 3A
KMT2C lysine (K)-specific methyltransferase 2C
KRTAP13-4 keratin associated protein 13-4
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LDLR low density lipoprotein receptor
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LIN28B lin-28 homolog B (C. elegans)
LOXHD1 lipoxygenase homology domains 1
LRRC16A leucine rich repeat containing 16A
LUC7L LUC7-like (S. cerevisiae)
LYRM1 LYR motif containing 1
LYSMD4 LysM, putative peptidoglycan-binding, domain containing 4
MAGEB16 melanoma antigen family B16
MAP2 microtubule-associated protein 2
MAP4 microtubule-associated protein 4
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MCRS1 microspherule protein 1
MED26 mediator complex subunit 26
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
MKI67 marker of proliferation Ki-67
MMRN2 multimerin 2
MMS22L MMS22-like, DNA repair protein
MRPS7 mitochondrial ribosomal protein S7
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC4 mucin 4, cell surface associated
MXRA5 matrix-remodelling associated 5
MYO1F myosin IF
NEK4 NIMA-related kinase 4
NIN ninein (GSK3B interacting protein)
NIP7 NIP7, nucleolar pre-rRNA processing protein
NOP56 NOP56 ribonucleoprotein
NOV nephroblastoma overexpressed
NPSR1 neuropeptide S receptor 1
NRCAM neuronal cell adhesion molecule
NSD1 nuclear receptor binding SET domain protein 1
NSMCE1 non-SMC element 1 homolog (S. cerevisiae)
OFD1 oral-facial-digital syndrome 1
OR10J5 olfactory receptor, family 10, subfamily J, member 5
OR14I1 olfactory receptor, family 14, subfamily I, member 1
OR2L3 olfactory receptor, family 2, subfamily L, member 3
OR5K3 olfactory receptor, family 5, subfamily K, member 3
OR5P3 olfactory receptor, family 5, subfamily P, member 3
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PAQR5 progestin and adipoQ receptor family member V
PBRM1 polybromo 1
PCDHB18P protocadherin beta 18 pseudogene
PCLO piccolo presynaptic cytomatrix protein
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PDE7A phosphodiesterase 7A
PDE8A phosphodiesterase 8A
PDLIM2 PDZ and LIM domain 2 (mystique)
PFKP phosphofructokinase, platelet
PHKB phosphorylase kinase, beta
PKP2 plakophilin 2
PLCE1 phospholipase C, epsilon 1
PLEC plectin
POLQ polymerase (DNA directed), theta
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
PPP1R3B protein phosphatase 1, regulatory subunit 3B
PRSS1 protease, serine, 1 (trypsin 1)
PSME4 proteasome (prosome, macropain) activator subunit 4
PTH2R parathyroid hormone 2 receptor
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PYCR2 pyrroline-5-carboxylate reductase family, member 2
RASGRP4 RAS guanyl releasing protein 4
RCC1 regulator of chromosome condensation 1
RCN1 reticulocalbin 1, EF-hand calcium binding domain
REM1 RAS (RAD and GEM)-like GTP-binding 1
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RHOBTB2 Rho-related BTB domain containing 2
RIN3 Ras and Rab interactor 3
RRBP1 ribosome binding protein 1
RYR2 ryanodine receptor 2 (cardiac)
SACS sacsin molecular chaperone
SAXO1 stabilizer of axonemal microtubules 1
SCPEP1 serine carboxypeptidase 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SDK2 sidekick cell adhesion molecule 2
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SELV selenoprotein V
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SESTD1 SEC14 and spectrin domains 1
SETD2 SET domain containing 2
SH2D6 SH2 domain containing 6
SH2D7 SH2 domain containing 7
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC25A53 solute carrier family 25, member 53
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC30A10 solute carrier family 30, member 10
SLC37A2 solute carrier family 37 (glucose-6-phosphate transporter), member 2
SLIT2 slit homolog 2 (Drosophila)
SMC4 structural maintenance of chromosomes 4
SMOC2 SPARC related modular calcium binding 2
SMYD4 SET and MYND domain containing 4
SNX2 sorting nexin 2
SOS1 son of sevenless homolog 1 (Drosophila)
SPEN spen family transcriptional repressor
SPHK2 sphingosine kinase 2
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
STX6 syntaxin 6
SYNJ1 synaptojanin 1
TACC2 transforming, acidic coiled-coil containing protein 2
TADA1 transcriptional adaptor 1
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBXAS1 thromboxane A synthase 1 (platelet)
TCEAL4 transcription elongation factor A (SII)-like 4
TDRD12 tudor domain containing 12
TEX35 testis expressed 35
TGM4 transglutaminase 4
THAP3 THAP domain containing, apoptosis associated protein 3
THAP9 THAP domain containing 9
TIAM2 T-cell lymphoma invasion and metastasis 2
TLE3 transducin-like enhancer of split 3
TLN1 talin 1
TLN2 talin 2
TM9SF4 transmembrane 9 superfamily protein member 4
TMEM161A transmembrane protein 161A
TMEM59 transmembrane protein 59
TP53BP2 tumor protein p53 binding protein 2
TRAM2 translocation associated membrane protein 2
TRIM25 tripartite motif containing 25
TRIM64C tripartite motif containing 64C
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TSC1 tuberous sclerosis 1
TSPAN33 tetraspanin 33
TSSK4 testis-specific serine kinase 4
TTN titin
TUBGCP6 tubulin, gamma complex associated protein 6
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UNC5A unc-5 homolog A (C. elegans)
UPB1 ureidopropionase, beta
USP25 ubiquitin specific peptidase 25
USP53 ubiquitin specific peptidase 53
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
VSTM1 V-set and transmembrane domain containing 1
VTN vitronectin
VWA3B von Willebrand factor A domain containing 3B
WDR11 WD repeat domain 11
WDR59 WD repeat domain 59
WDR62 WD repeat domain 62
WWC1 WW and C2 domain containing 1
ZBED9 zinc finger, BED-type containing 9
ZC3H4 zinc finger CCCH-type containing 4
ZCCHC16 zinc finger, CCHC domain containing 16
ZDHHC7 zinc finger, DHHC-type containing 7
ZFHX4 zinc finger homeobox 4
ZFPM2 zinc finger protein, FOG family member 2
ZNF215 zinc finger protein 215
ZNF263 zinc finger protein 263
ZNF287 zinc finger protein 287
ZNF362 zinc finger protein 362
ZNF366 zinc finger protein 366
ZNF462 zinc finger protein 462
ZNF544 zinc finger protein 544
ZNF582 zinc finger protein 582
ZNF669 zinc finger protein 669
ZNF736 zinc finger protein 736