REC8 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description REC8 meiotic recombination protein|This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9985)
External Link http://www.ncbi.nlm.nih.gov/gene/9985
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Genes

15 interacting proteins for REC8 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ATR ATR serine/threonine kinase
BAG2 BCL2-associated athanogene 2
BRCA1 breast cancer 1, early onset
CACYBP calcyclin binding protein
MLF1 myeloid leukemia factor 1
MLF2 myeloid leukemia factor 2
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SMC1A structural maintenance of chromosomes 1A
SMC1B structural maintenance of chromosomes 1B
SMC3 structural maintenance of chromosomes 3
STIP1 stress-induced phosphoprotein 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SYCP3 synaptonemal complex protein 3