| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | v-rel avian reticuloendotheliosis viral oncogene homolog|This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 5966) |
| External Link | https://ncbi.nlm.nih.gov/gene/5966 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the REL gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RGS5 | regulator of G-protein signaling 5 | 0.0148405 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0138647 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0128153 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.0125081 |
| ASPN | asporin | 0.0118494 |
| THBS2 | thrombospondin 2 | 0.0117121 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.0112304 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.0110441 |
| AREG | amphiregulin | 0.0107475 |
| CLEC3B | C-type lectin domain family 3, member B | 0.0106474 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0105842 |
| A2M | alpha-2-macroglobulin | 0.0104553 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.0103458 |
| NPY1R | neuropeptide Y receptor Y1 | 0.0102686 |
| POU2AF1 | POU class 2 associating factor 1 | 0.010134 |
| METTL7A | methyltransferase like 7A | 0.0100402 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.0099818 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00988466 |
| MT1E | metallothionein 1E | 0.00981282 |
| PLK1 | polo-like kinase 1 | 0.00980413 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00967022 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00961158 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0095686 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00946533 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.00933108 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.00926453 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0091354 |
| IL6R | interleukin 6 receptor | 0.00908263 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.00906907 |
| GPR137B | G protein-coupled receptor 137B | 0.0089657 |
| GPX1 | glutathione peroxidase 1 | 0.00895056 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00873334 |
| PDGFRL | platelet-derived growth factor receptor-like | 0.00872162 |
| C3 | complement component 3 | 0.00870353 |
| CRABP1 | cellular retinoic acid binding protein 1 | 0.00866156 |
| RBM47 | RNA binding motif protein 47 | 0.00865948 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.00855531 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00854362 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00852913 |
| CYBA | cytochrome b-245, alpha polypeptide | 0.00850657 |
| ISYNA1 | inositol-3-phosphate synthase 1 | 0.00850013 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00835227 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00823614 |
| MFAP5 | microfibrillar associated protein 5 | 0.00820558 |
| FN1 | fibronectin 1 | 0.00815007 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00814259 |
| CD93 | CD93 molecule | 0.00811618 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00808137 |
| KDSR | 3-ketodihydrosphingosine reductase | 0.0079727 |
| TMEM176B | transmembrane protein 176B | 0.00782858 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.00776942 |
| LEFTY1 | left-right determination factor 1 | 0.0077151 |
| BPIFA1 | BPI fold containing family A, member 1 | 0.00763841 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.00759862 |
| BAX | BCL2-associated X protein | 0.00756187 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.00752608 |
| MT1X | metallothionein 1X | 0.00749173 |
| TXLNA | taxilin alpha | 0.00748987 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00747031 |
| NPEPL1 | aminopeptidase-like 1 | 0.00745832 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00728258 |
| MGP | matrix Gla protein | 0.00727317 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00726175 |
| C1ORF54 | chromosome 1 open reading frame 54 | 0.00726051 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00723578 |
| TMEM176A | transmembrane protein 176A | 0.00720687 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00717427 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00713838 |
| NDRG2 | NDRG family member 2 | 0.00707511 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 0.00699506 |
| SELENOW | selenoprotein W | 0.00695348 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.00694784 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00694123 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | 0.00689617 |
| MT1H | metallothionein 1H | 0.00689044 |
| PCDH17 | protocadherin 17 | 0.00685102 |
| SFRP4 | secreted frizzled-related protein 4 | 0.0068466 |
| TFCP2L1 | transcription factor CP2-like 1 | 0.00680865 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00680106 |
| THBS1 | thrombospondin 1 | 0.00679727 |
| WDR7 | WD repeat domain 7 | 0.00679112 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0067502 |
| XPO7 | exportin 7 | 0.00670696 |
| CTSH | cathepsin H | 0.00669222 |
| MT1F | metallothionein 1F | 0.00667456 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00666247 |
| MT1G | metallothionein 1G | 0.0066595 |
| CFH | complement factor H | 0.00659784 |
| CLTB | clathrin, light chain B | 0.00656314 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | 0.00654912 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0065404 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00653156 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00651286 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00650563 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) | 0.00650077 |
| GAS6 | growth arrest-specific 6 | 0.00648844 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00647709 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00644682 |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 0.00643455 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00642323 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | 0.00641841 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00641737 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00637081 |
| PDGFD | platelet derived growth factor D | 0.00630276 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.00629717 |
| NUTF2 | nuclear transport factor 2 | 0.00627357 |
| C4BPA | complement component 4 binding protein, alpha | 0.00625574 |
| METRN | meteorin, glial cell differentiation regulator | 0.00624138 |
| FLT3 | fms-related tyrosine kinase 3 | 0.00623326 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.0062013 |
| IPO13 | importin 13 | 0.00618467 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.00613745 |
| SHTN1 | shootin 1 | 0.00611135 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.00609462 |
| IER3 | immediate early response 3 | 0.00607905 |
| PLA2G10 | phospholipase A2, group X | 0.00606776 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.00605231 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0060068 |
| PLK2 | polo-like kinase 2 | 0.0060059 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit | 0.00600051 |
| RUVBL1 | RuvB-like AAA ATPase 1 | 0.00599851 |
| LGMN | legumain | 0.00598594 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00596924 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 0.00595271 |
| KLF2 | Kruppel-like factor 2 | 0.00593562 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | 0.005935 |
| BTG2 | BTG family, member 2 | 0.00593087 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.00591379 |
| GPX3 | glutathione peroxidase 3 | 0.0058838 |
| ICAM2 | intercellular adhesion molecule 2 | 0.00588296 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00586447 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00586279 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.00585743 |
| SETBP1 | SET binding protein 1 | 0.00584123 |
| SLIT1 | slit homolog 1 (Drosophila) | 0.00583895 |
| CREBL2 | cAMP responsive element binding protein-like 2 | 0.00582684 |
| CRLF1 | cytokine receptor-like factor 1 | 0.00582344 |
| TRIM8 | tripartite motif containing 8 | 0.00582077 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00580312 |
| HMGB3 | high mobility group box 3 | 0.00579685 |
| COL14A1 | collagen, type XIV, alpha 1 | 0.00579654 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.0057836 |
| CLDN7 | claudin 7 | 0.00578345 |
| KLF6 | Kruppel-like factor 6 | 0.00575892 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.00575667 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | 0.005755 |
| MCAM | melanoma cell adhesion molecule | 0.00573986 |
| YBX1 | Y box binding protein 1 | 0.00573977 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00573076 |
| MVP | major vault protein | 0.00572194 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.00571789 |
| NCAN | neurocan | 0.00570923 |
| PALLD | palladin, cytoskeletal associated protein | 0.00570275 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.0056927 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | 0.00568493 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.00568492 |
| AKIRIN1 | akirin 1 | 0.00568405 |
| JUND | jun D proto-oncogene | 0.00568167 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00567847 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.00567191 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.00567074 |
| EFHD1 | EF-hand domain family, member D1 | 0.0056375 |
| PROM1 | prominin 1 | 0.00562833 |
| RPS27L | ribosomal protein S27-like | 0.00559513 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.00559144 |
| HABP2 | hyaluronan binding protein 2 | 0.00558976 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 | 0.00558487 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 | 0.00557935 |
| INSR | insulin receptor | 0.0055785 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00556629 |
| ISOC2 | isochorismatase domain containing 2 | 0.00556249 |
| AHCY | adenosylhomocysteinase | 0.00555856 |
| LAT2 | linker for activation of T cells family, member 2 | 0.00555732 |
| COL9A3 | collagen, type IX, alpha 3 | 0.0055529 |
| MARCKSL1 | MARCKS-like 1 | 0.00554809 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00554675 |
| SLC66A2 | solute carrier family 66 member 2 | 0.00554323 |
| SMAD2 | SMAD family member 2 | 0.00550746 |
| TSPAN4 | tetraspanin 4 | 0.00550728 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.0055033 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | 0.0054979 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00549595 |
| ATP5F1D | ATP synthase F1 subunit delta | 0.00548173 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.00547708 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00547394 |
| PLIN3 | perilipin 3 | 0.00546512 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha | 0.00546032 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00545088 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.00544723 |
| CCL21 | chemokine (C-C motif) ligand 21 | 0.00544305 |
| KIAA0930 | KIAA0930 | 0.00544057 |
| GPNMB | glycoprotein (transmembrane) nmb | 0.00542544 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.00542283 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00541938 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.00541767 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00541534 |
| CAPG | capping protein (actin filament), gelsolin-like | 0.00541252 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00541218 |
| GOLGA8H | golgin A8 family, member H | 0.0054116 |
| SH2B3 | SH2B adaptor protein 3 | 0.00540648 |
| NOP53 | NOP53 ribosome biogenesis factor | 0.00539946 |
| BLNK | B-cell linker | 0.00539055 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.0053706 |
| ATP6V0D1 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 | 0.00536702 |
| TGFA | transforming growth factor, alpha | 0.00535711 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.005345 |
| SCARB1 | scavenger receptor class B, member 1 | 0.00534237 |
| DBN1 | drebrin 1 | 0.00533256 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) | 0.00531241 |
| XIC | X chromosome inactivation center | 0.00531144 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00529377 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.00529369 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | 0.00529329 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.00528842 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 | 0.00528723 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.00528109 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.00528 |
| TUBA1A | tubulin, alpha 1a | 0.00527983 |
| NDN | necdin, melanoma antigen (MAGE) family member | 0.00527844 |
| CYRIA | CYFIP related Rac1 interactor A | 0.00526072 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 | 0.00524579 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00524207 |
| GRB14 | growth factor receptor-bound protein 14 | 0.00523937 |
| CD37 | CD37 molecule | 0.00523306 |
| CTSD | cathepsin D | 0.00517048 |
| ADIRF | adipogenesis regulatory factor | 0.00515664 |
| CD81 | CD81 molecule | 0.00515068 |
| TWF2 | twinfilin actin binding protein 2 | 0.00515001 |
| FGL1 | fibrinogen-like 1 | 0.00514983 |
| AMBP | alpha-1-microglobulin/bikunin precursor | 0.00514009 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.0051336 |
| PNMA8A | PNMA family member 8A | 0.00512045 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.0051195 |
| KRT14 | keratin 14, type I | 0.00511324 |
| KIAA0040 | KIAA0040 | 0.00510686 |
| PTK2 | protein tyrosine kinase 2 | 0.0050943 |
| PBLD | phenazine biosynthesis-like protein domain containing | 0.00508014 |
| KRT8 | keratin 8, type II | 0.00507383 |
| SLA | Src-like-adaptor | 0.00507137 |
| PPIF | peptidylprolyl isomerase F | 0.00506905 |
| MIA | melanoma inhibitory activity | 0.00506817 |
| CHEK2 | checkpoint kinase 2 | 0.00506744 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00505745 |
| CPM | carboxypeptidase M | 0.00505494 |
| MYH11 | myosin, heavy chain 11, smooth muscle | 0.00504684 |
| CISH | cytokine inducible SH2-containing protein | 0.00503681 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00503515 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 0.00503272 |
| ANPEP | alanyl (membrane) aminopeptidase | 0.00503224 |
| TBCB | tubulin folding cofactor B | 0.00502583 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0210372 |
| S100A9 | S100 calcium binding protein A9 | -0.0156415 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.0152693 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.015202 |
| S100A8 | S100 calcium binding protein A8 | -0.0147826 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.013796 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0137467 |
| ANXA3 | annexin A3 | -0.0136312 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0132085 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.0128496 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.0121052 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0120737 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.0113484 |
| LTF | lactotransferrin | -0.0107976 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.0103261 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.0103028 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.0102795 |
| KIF20A | kinesin family member 20A | -0.00980232 |
| CLC | Charcot-Leyden crystal galectin | -0.00978458 |
| S100P | S100 calcium binding protein P | -0.00969395 |
| S100A12 | S100 calcium binding protein A12 | -0.009607 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00952709 |
| ELANE | elastase, neutrophil expressed | -0.00932205 |
| CADM1 | cell adhesion molecule 1 | -0.00931049 |
| HBD | hemoglobin, delta | -0.00927891 |
| CD69 | CD69 molecule | -0.00915562 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00912352 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00910989 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00908404 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.00895662 |
| IFI44 | interferon-induced protein 44 | -0.00889749 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00889052 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.00888834 |
| NTS | neurotensin | -0.00879736 |
| WT1 | Wilms tumor 1 | -0.0087743 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0087326 |
| CPD | carboxypeptidase D | -0.00872223 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00870046 |
| AGR2 | anterior gradient 2 | -0.00864286 |
| ITK | IL2-inducible T-cell kinase | -0.0085606 |
| HBB | hemoglobin, beta | -0.00855642 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00853567 |
| MAP7 | microtubule-associated protein 7 | -0.00851436 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00847843 |
| ANXA1 | annexin A1 | -0.00846907 |
| PCP4 | Purkinje cell protein 4 | -0.00838243 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00837316 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0082623 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00815719 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00812552 |
| TPD52L1 | tumor protein D52-like 1 | -0.0081228 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00801533 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00800008 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00795552 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00793926 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00791499 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00790239 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.00790168 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | -0.00778933 |
| CHN1 | chimerin 1 | -0.00777113 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00767325 |
| IRS2 | insulin receptor substrate 2 | -0.00767072 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00766588 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00764773 |
| MGAM | maltase-glucoamylase | -0.00756078 |
| TDO2 | tryptophan 2,3-dioxygenase | -0.00751362 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.00751332 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.007506 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | -0.00749433 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | -0.00749426 |
| SRSF7 | serine/arginine-rich splicing factor 7 | -0.00747523 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00742794 |
| NPR3 | natriuretic peptide receptor 3 | -0.00741814 |
| PDGFC | platelet derived growth factor C | -0.00738925 |
| ARL4A | ADP-ribosylation factor-like 4A | -0.00736395 |
| TMEM100 | transmembrane protein 100 | -0.00728401 |
| CSTA | cystatin A (stefin A) | -0.00723899 |
| HDC | histidine decarboxylase | -0.00713508 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00712642 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.0071154 |
| LYZ | lysozyme | -0.00706696 |
| PER3 | period circadian clock 3 | -0.0070353 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | -0.00702339 |
| CAV2 | caveolin 2 | -0.00694788 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | -0.00694365 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.00692977 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.0069191 |
| IFT57 | intraflagellar transport 57 | -0.00690169 |
| PRSS21 | protease, serine, 21 (testisin) | -0.00685474 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00680333 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00678961 |
| NMU | neuromedin U | -0.00678833 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00677413 |
| NOTCH2 | notch 2 | -0.00677122 |
| PSAT1 | phosphoserine aminotransferase 1 | -0.00674073 |
| CHIT1 | chitinase 1 (chitotriosidase) | -0.00662119 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | -0.00661587 |
| PGD | phosphogluconate dehydrogenase | -0.00659777 |
| KYNU | kynureninase | -0.00658725 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00657672 |
| MMP7 | matrix metallopeptidase 7 | -0.00654332 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | -0.00653084 |
| CTSG | cathepsin G | -0.00652843 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00652394 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00652003 |
| CLGN | calmegin | -0.00651818 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00650158 |
| IFI44L | interferon-induced protein 44-like | -0.00649811 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00648924 |
| C1ORF56 | chromosome 1 open reading frame 56 | -0.00646332 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00645694 |
| NUP160 | nucleoporin 160kDa | -0.00645425 |
| RPL10 | ribosomal protein L10 | -0.00645227 |
| BTN3A2 | butyrophilin, subfamily 3, member A2 | -0.00643172 |
| LPAR6 | lysophosphatidic acid receptor 6 | -0.00642995 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00641841 |
| CST7 | cystatin F (leukocystatin) | -0.00641745 |
| KLK11 | kallikrein-related peptidase 11 | -0.00641066 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00640353 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | -0.00640112 |
| MRPS16 | mitochondrial ribosomal protein S16 | -0.00639299 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00630833 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.00626966 |
| RALB | v-ral simian leukemia viral oncogene homolog B | -0.0062552 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.00624816 |
| TARP | TCR gamma alternate reading frame protein | -0.00624699 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.00624383 |
| YAP1 | Yes-associated protein 1 | -0.00623212 |
| ZMYND11 | zinc finger, MYND-type containing 11 | -0.00622658 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | -0.00621893 |
| CDR2L | cerebellar degeneration-related protein 2-like | -0.00621339 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00621213 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00620192 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.00619783 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00619686 |
| KAZN | kazrin, periplakin interacting protein | -0.00618503 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00618303 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00617679 |
| TOB1 | transducer of ERBB2, 1 | -0.0061641 |
| AUTS2 | autism susceptibility candidate 2 | -0.00615242 |
| ANKRD49 | ankyrin repeat domain 49 | -0.00614818 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.00613225 |
| MID1 | midline 1 | -0.00612995 |
| SRSF1 | serine/arginine-rich splicing factor 1 | -0.00609918 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00608274 |
| GPM6A | glycoprotein M6A | -0.00607171 |
| LOX | lysyl oxidase | -0.00606552 |
| ESYT1 | extended synaptotagmin-like protein 1 | -0.0060383 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00603589 |
| CAMP | cathelicidin antimicrobial peptide | -0.00600707 |
| ANOS1 | anosmin 1 | -0.00599615 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00597205 |
| NXN | nucleoredoxin | -0.00596969 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00596055 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00596037 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.00593179 |
| FZD6 | frizzled class receptor 6 | -0.00589145 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 | -0.00587838 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00586869 |
| UQCRFS1 | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | -0.00585714 |
| CNPY2 | canopy FGF signaling regulator 2 | -0.00582554 |
| THAP9-AS1 | THAP9 antisense RNA 1 | -0.00580754 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.0058045 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0058007 |
| BPI | bactericidal/permeability-increasing protein | -0.00579745 |
| GPR65 | G protein-coupled receptor 65 | -0.00578727 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.00578261 |
| POF1B | premature ovarian failure, 1B | -0.00577865 |
| HOXB7 | homeobox B7 | -0.00577331 |
| PRKCA | protein kinase C, alpha | -0.00574517 |
| NDNF | neuron-derived neurotrophic factor | -0.00574283 |
| TMEM106C | transmembrane protein 106C | -0.00573744 |
| REXO2 | RNA exonuclease 2 | -0.00569726 |
| TMEM126B | transmembrane protein 126B | -0.00569456 |
| FHL1 | four and a half LIM domains 1 | -0.00565978 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00564427 |
| TMPRSS11E | transmembrane protease, serine 11E | -0.00564377 |
| KLK2 | kallikrein-related peptidase 2 | -0.00564235 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00563695 |
| HLA-DMB | major histocompatibility complex, class II, DM beta | -0.00559776 |
| SMAD5 | SMAD family member 5 | -0.00556423 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.00556364 |
| AIMP1 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 | -0.00556287 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | -0.00556121 |
| KLK8 | kallikrein-related peptidase 8 | -0.00555454 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | -0.0055511 |
| ING2 | inhibitor of growth family, member 2 | -0.00553552 |
| MEIS2 | Meis homeobox 2 | -0.00553066 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | -0.0055272 |
| LYST | lysosomal trafficking regulator | -0.00552538 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.00551612 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.00550839 |
| CSAD | cysteine sulfinic acid decarboxylase | -0.00549518 |
| C9ORF3 | chromosome 9 open reading frame 3 | -0.00548963 |
| KYAT3 | kynurenine aminotransferase 3 | -0.005489 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.00547348 |
| RGCC | regulator of cell cycle | -0.00545899 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.00543883 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00543739 |
| MTMR2 | myotubularin related protein 2 | -0.00541338 |
| SLC35E2B | solute carrier family 35, member E2B | -0.00541147 |
| TMSB15A | thymosin beta 15a | -0.00540994 |
| MEIS1 | Meis homeobox 1 | -0.00540067 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | -0.00539603 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | -0.00538443 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.00537883 |
| APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A | -0.00536515 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00533792 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00532753 |
| GPATCH8 | G patch domain containing 8 | -0.00531777 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | -0.00531033 |
| MPO | myeloperoxidase | -0.00529375 |
| CA3 | carbonic anhydrase III | -0.00529222 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0052772 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.00527619 |
| CD48 | CD48 molecule | -0.00527055 |
| TTC37 | tetratricopeptide repeat domain 37 | -0.00525974 |
| BDNF | brain-derived neurotrophic factor | -0.00525745 |
| CLEC5A | C-type lectin domain family 5, member A | -0.0052564 |
| CHPT1 | choline phosphotransferase 1 | -0.00524043 |
| PLBD1 | phospholipase B domain containing 1 | -0.00522226 |
| TENM3 | teneurin transmembrane protein 3 | -0.00521719 |
| GPR171 | G protein-coupled receptor 171 | -0.005215 |
| CANX | calnexin | -0.00520893 |
| CDC7 | cell division cycle 7 | -0.00520355 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00520291 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 | -0.00519115 |
| INHBB | inhibin, beta B | -0.00518547 |
| LYPD1 | LY6/PLAUR domain containing 1 | -0.00518468 |
| SUSD4 | sushi domain containing 4 | -0.00516104 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.0051601 |
| HIST1H2AE | histone cluster 1, H2ae | -0.00515903 |
| EPHB2 | EPH receptor B2 | -0.00514269 |
| CETN2 | centrin, EF-hand protein, 2 | -0.00513413 |
| TCF21 | transcription factor 21 | -0.00511786 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.00511268 |
| COMMD3 | COMM domain containing 3 | -0.00511023 |
| VCPKMT | valosin containing protein lysine (K) methyltransferase | -0.00510206 |
| ORMDL2 | ORMDL sphingolipid biosynthesis regulator 2 | -0.00509163 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0050824 |
| OSBPL10 | oxysterol binding protein-like 10 | -0.00507627 |
| MMP2 | matrix metallopeptidase 2 | -0.00507529 |
| BIN2 | bridging integrator 2 | -0.00506249 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.00506179 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | -0.00504837 |
| NREP | neuronal regeneration related protein | -0.00504244 |
| MRPL42 | mitochondrial ribosomal protein L42 | -0.00503561 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.00502266 |
| FLNA | filamin A, alpha | -0.0050201 |
