REL Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description v-rel avian reticuloendotheliosis viral oncogene homolog|This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 5966)
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Genes

212 target genes of the REL transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADTRP androgen-dependent TFPI-regulating protein
AGO1 argonaute RISC catalytic component 1
AHDC1 AT hook, DNA binding motif, containing 1
AHI1 Abelson helper integration site 1
ALG6 ALG6, alpha-1,3-glucosyltransferase
ANK2 ankyrin 2, neuronal
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGAP26-AS1 ARHGAP26 antisense RNA 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL14 ADP-ribosylation factor-like 14
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
B2M beta-2-microglobulin
BCL3 B-cell CLL/lymphoma 3
BCL6B B-cell CLL/lymphoma 6, member B
BICC1 BicC family RNA binding protein 1
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BMP2K BMP2 inducible kinase
BSPRY B-box and SPRY domain containing
C10ORF55 chromosome 10 open reading frame 55
CA14 carbonic anhydrase XIV
CACHD1 cache domain containing 1
CALR calreticulin
CAMTA1 calmodulin binding transcription activator 1
CCL20 chemokine (C-C motif) ligand 20
CD82 CD82 molecule
CD86 CD86 molecule
CDK8 cyclin-dependent kinase 8
CEP152 centrosomal protein 152kDa
CHD2 chromodomain helicase DNA binding protein 2
CLIC5 chloride intracellular channel 5
CLPTM1 cleft lip and palate associated transmembrane protein 1
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COMMD3 COMM domain containing 3
COMMD3-BMI1 COMMD3-BMI1 readthrough
CREB1 cAMP responsive element binding protein 1
CSF1 colony stimulating factor 1 (macrophage)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSRP1 cysteine and glycine-rich protein 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYLD cylindromatosis (turban tumor syndrome)
DSP desmoplakin
DTX3 deltex 3, E3 ubiquitin ligase
DTX4 deltex 4, E3 ubiquitin ligase
DUSP22 dual specificity phosphatase 22
E2F5 E2F transcription factor 5, p130-binding
EDNRA endothelin receptor type A
EFCAB6 EF-hand calcium binding domain 6
EGFR epidermal growth factor receptor
EGOT eosinophil granule ontogeny transcript (non-protein coding)
EGR2 early growth response 2
EHBP1L1 EH domain binding protein 1-like 1
EHF ets homologous factor
EIF4A2 eukaryotic translation initiation factor 4A2
EIF5A eukaryotic translation initiation factor 5A
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EML2 echinoderm microtubule associated protein like 2
ENO1 enolase 1, (alpha)
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
ETV3L ets variant 3-like
FAM162A family with sequence similarity 162, member A
FAM187A family with sequence similarity 187, member A
FAM189A2 family with sequence similarity 189, member A2
FBRS fibrosin
FFAR2 free fatty acid receptor 2
FLJ16124
FLJ31104 uncharacterized LOC441072
FTHL17 ferritin, heavy polypeptide-like 17
FXYD7 FXYD domain containing ion transport regulator 7
GADD45B growth arrest and DNA-damage-inducible, beta
GATA4 GATA binding protein 4
GDNF-AS1 GDNF antisense RNA 1 (head to head)
GLRA2 glycine receptor, alpha 2
GPBP1 GC-rich promoter binding protein 1
GPC6 glypican 6
GREM1 gremlin 1, DAN family BMP antagonist
GRK5 G protein-coupled receptor kinase 5
HDAC9 histone deacetylase 9
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HES1 hes family bHLH transcription factor 1
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HLA-DMA major histocompatibility complex, class II, DM alpha
HS1BP3 HCLS1 binding protein 3
ICAM1 intercellular adhesion molecule 1
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL13RA1 interleukin 13 receptor, alpha 1
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
IL25 interleukin 25
INADL InaD-like (Drosophila)
IRF8 interferon regulatory factor 8
ITPKC inositol-trisphosphate 3-kinase C
KAT7 K(lysine) acetyltransferase 7
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KDM2A lysine (K)-specific demethylase 2A
KIAA0368 KIAA0368
KIAA1217 KIAA1217
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF5 Kruppel-like factor 5 (intestinal)
KLHL5 kelch-like family member 5
KMT2A lysine (K)-specific methyltransferase 2A
KREMEN2 kringle containing transmembrane protein 2
KRTAP13-1 keratin associated protein 13-1
KSR1 kinase suppressor of ras 1
L1CAM L1 cell adhesion molecule
LAMP5 lysosomal-associated membrane protein family, member 5
LINC00486 long intergenic non-protein coding RNA 486
LINC00570 long intergenic non-protein coding RNA 570
LINC01549 long intergenic non-protein coding RNA 1549
LOC284648 uncharacterized LOC284648
LOC646626 uncharacterized LOC646626
LOC729683 uncharacterized LOC729683
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRC7 leucine rich repeat containing 7
LTB lymphotoxin beta (TNF superfamily, member 3)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAMDC2 MAM domain containing 2
MED8 mediator complex subunit 8
METTL1 methyltransferase like 1
MFSD11 major facilitator superfamily domain containing 11
MIR1538 microRNA 1538
MIR1915 microRNA 1915
MIR3935 microRNA 3935
MIR4285 microRNA 4285
MIR4322 microRNA 4322
MIR4505 microRNA 4505
MIR4792 microRNA 4792
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP9 matrix metallopeptidase 9
MSL1 male-specific lethal 1 homolog (Drosophila)
MSX1 msh homeobox 1
MYB v-myb avian myeloblastosis viral oncogene homolog
NAMA non-protein coding RNA, associated with MAP kinase pathway and growth arrest
NCS1 neuronal calcium sensor 1
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NEBL-AS1 NEBL antisense RNA 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NLK nemo-like kinase
NTNG1 netrin G1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
ORAI1 ORAI calcium release-activated calcium modulator 1
PACS1 phosphofurin acidic cluster sorting protein 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PARK7 parkinson protein 7
PCDH10 protocadherin 10
PCDH9 protocadherin 9
PDZD2 PDZ domain containing 2
PEA15 phosphoprotein enriched in astrocytes 15
PFN1 profilin 1
PI3 peptidase inhibitor 3, skin-derived
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PNKD paroxysmal nonkinesigenic dyskinesia
POU2F3 POU class 2 homeobox 3
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C
PPP6C protein phosphatase 6, catalytic subunit
PQBP1 polyglutamine binding protein 1
PRDM12 PR domain containing 12
PSD pleckstrin and Sec7 domain containing
PTPRR protein tyrosine phosphatase, receptor type, R
RAB10 RAB10, member RAS oncogene family
RAB12 RAB12, member RAS oncogene family
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RBP5 retinol binding protein 5, cellular
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RELT RELT tumor necrosis factor receptor
RIPK2 receptor-interacting serine-threonine kinase 2
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RYR3 ryanodine receptor 3
SCAF1 SR-related CTD-associated factor 1
SEC24A SEC24 family member A
SETD5 SET domain containing 5
SH2B3 SH2B adaptor protein 3
SLC12A8 solute carrier family 12, member 8
SMAD3 SMAD family member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOCS2 suppressor of cytokine signaling 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX13 SRY (sex determining region Y)-box 13
ST7 suppression of tumorigenicity 7
STXBP5L syntaxin binding protein 5-like
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae)
SYNPO synaptopodin
TBC1D17 TBC1 domain family, member 17
TBC1D22B TBC1 domain family, member 22B
TDRD10 tudor domain containing 10
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8
TNK2 tyrosine kinase, non-receptor, 2
TOM1L1 target of myb1 (chicken)-like 1
TOR3A torsin family 3, member A
TRPT1 tRNA phosphotransferase 1
TUBGCP4 tubulin, gamma complex associated protein 4
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBL7 ubiquitin-like 7
UCK2 uridine-cytidine kinase 2
VANGL2 VANGL planar cell polarity protein 2
VASH2 vasohibin 2
VCAN versican
VIM vimentin
VRTN vertebrae development associated
ZBTB1 zinc finger and BTB domain containing 1
ZBTB39 zinc finger and BTB domain containing 39
ZC3H12A zinc finger CCCH-type containing 12A
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase