REL Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description v-rel avian reticuloendotheliosis viral oncogene homolog|This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 5966)
External Link http://www.ncbi.nlm.nih.gov/gene/5966
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151 interacting proteins for REL from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACTG1 actin gamma 1
ADRB2 adrenoceptor beta 2, surface
ADSL adenylosuccinate lyase
ANKHD1 ankyrin repeat and KH domain containing 1
ANKRD28 ankyrin repeat domain 28
AR androgen receptor
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BCL3 B-cell CLL/lymphoma 3
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C1QBP complement component 1, q subcomponent binding protein
C9ORF91 chromosome 9 open reading frame 91
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCNE1 cyclin E1
CD3EAP CD3e molecule, epsilon associated protein
CDK2 cyclin-dependent kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CLIC4 chloride intracellular channel 4
CLTC clathrin, heavy chain (Hc)
COMMD1 copper metabolism (Murr1) domain containing 1
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
CREBBP CREB binding protein
CUL1 cullin 1
CXCL14 chemokine (C-X-C motif) ligand 14
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DGCR6 DiGeorge syndrome critical region gene 6
DPF2 D4, zinc and double PHD fingers family 2
ELF1 E74-like factor 1 (ets domain transcription factor)
EP300 E1A binding protein p300
FBXW11 F-box and WD repeat domain containing 11
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FHIT fragile histidine triad
FKBP5 FK506 binding protein 5
FOXP3 forkhead box P3
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GLG1 golgi glycoprotein 1
GTF2B general transcription factor IIB
GTF2I general transcription factor IIi
HDAC1 histone deacetylase 1
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HSPA1L heat shock 70kDa protein 1-like
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IQGAP2 IQ motif containing GTPase activating protein 2
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KPNA3 karyopherin alpha 3 (importin alpha 4)
LRPPRC leucine-rich pentatricopeptide repeat containing
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK8 mitogen-activated protein kinase 8
MCC mutated in colorectal cancers
MTIF2 mitochondrial translational initiation factor 2
MTPN myotrophin
MVP major vault protein
NDE1 nudE neurodevelopment protein 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NKRF NFKB repressing factor
NOTCH1 notch 1
PAPOLA poly(A) polymerase alpha
PARK2 parkin RBR E3 ubiquitin protein ligase
PDCD2 programmed cell death 2
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR1D polymerase (RNA) I polypeptide D, 16kDa
POLR1E polymerase (RNA) I polypeptide E, 53kDa
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PPP4C protein phosphatase 4, catalytic subunit
PPP6C protein phosphatase 6, catalytic subunit
PPP6R1 protein phosphatase 6, regulatory subunit 1
PPP6R2 protein phosphatase 6, regulatory subunit 2
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME4 proteasome (prosome, macropain) activator subunit 4
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
RASAL2 RAS protein activator like 2
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPL30 ribosomal protein L30
RPL6 ribosomal protein L6
RPS13 ribosomal protein S13
SEC16A SEC16 homolog A (S. cerevisiae)
SIN3A SIN3 transcription regulator family member A
SKP1 S-phase kinase-associated protein 1
SOCS3 suppressor of cytokine signaling 3
SP1 Sp1 transcription factor
SPAG9 sperm associated antigen 9
SRF serum response factor (c-fos serum response element-binding transcription factor)
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TBK1 TANK-binding kinase 1
TBP TATA box binding protein
TDO2 tryptophan 2,3-dioxygenase
TMEM165 transmembrane protein 165
TNIP1 TNFAIP3 interacting protein 1
TNIP2 TNFAIP3 interacting protein 2
TUBA3C tubulin, alpha 3c
TUBB tubulin, beta class I
TUBB4A tubulin, beta 4A class IVa
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
USP9X ubiquitin specific peptidase 9, X-linked
WDR37 WD repeat domain 37