RELA Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description v-rel avian reticuloendotheliosis viral oncogene homolog A|NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] (NCBI Entrez Gene Database, 5970)
Similar Terms
Downloads & Tools

Genes

170 target genes of the RELA transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
ADRBK2 adrenergic, beta, receptor kinase 2
ADTRP androgen-dependent TFPI-regulating protein
AGO1 argonaute RISC catalytic component 1
AHDC1 AT hook, DNA binding motif, containing 1
AHI1 Abelson helper integration site 1
ALAS1 5'-aminolevulinate synthase 1
ALG6 ALG6, alpha-1,3-glucosyltransferase
ANK2 ankyrin 2, neuronal
ANXA5 annexin A5
ARHGAP26-AS1 ARHGAP26 antisense RNA 1
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
B2M beta-2-microglobulin
BCL3 B-cell CLL/lymphoma 3
BCL6B B-cell CLL/lymphoma 6, member B
BICC1 BicC family RNA binding protein 1
BIRC3 baculoviral IAP repeat containing 3
BMP2K BMP2 inducible kinase
C10ORF55 chromosome 10 open reading frame 55
CACHD1 cache domain containing 1
CD40 CD40 molecule, TNF receptor superfamily member 5
CD86 CD86 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK8 cyclin-dependent kinase 8
CHD2 chromodomain helicase DNA binding protein 2
CHD9 chromodomain helicase DNA binding protein 9
CISD1 CDGSH iron sulfur domain 1
CLIC5 chloride intracellular channel 5
CLPTM1 cleft lip and palate associated transmembrane protein 1
COMMD3 COMM domain containing 3
COMMD3-BMI1 COMMD3-BMI1 readthrough
CREB1 cAMP responsive element binding protein 1
CSF1 colony stimulating factor 1 (macrophage)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSRP1 cysteine and glycine-rich protein 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYLD cylindromatosis (turban tumor syndrome)
DSP desmoplakin
DTX4 deltex 4, E3 ubiquitin ligase
EGFR epidermal growth factor receptor
EGOT eosinophil granule ontogeny transcript (non-protein coding)
EGR2 early growth response 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EML2 echinoderm microtubule associated protein like 2
ENO3 enolase 3 (beta, muscle)
ETV3L ets variant 3-like
FAM178B family with sequence similarity 178, member B
FAM187A family with sequence similarity 187, member A
FAM189A2 family with sequence similarity 189, member A2
FBRS fibrosin
FLJ31104 uncharacterized LOC441072
FOXP4 forkhead box P4
FOXS1 forkhead box S1
FTHL17 ferritin, heavy polypeptide-like 17
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GATA4 GATA binding protein 4
GLRA2 glycine receptor, alpha 2
GREM1 gremlin 1, DAN family BMP antagonist
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HMGB1 high mobility group box 1
HS1BP3 HCLS1 binding protein 3
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKZF3 IKAROS family zinc finger 3 (Aiolos)
INADL InaD-like (Drosophila)
IRF8 interferon regulatory factor 8
ITGB8 integrin, beta 8
ITPKC inositol-trisphosphate 3-kinase C
KAT7 K(lysine) acetyltransferase 7
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KDM2A lysine (K)-specific demethylase 2A
KIAA0368 KIAA0368
KIAA1217 KIAA1217
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KREMEN2 kringle containing transmembrane protein 2
KSR1 kinase suppressor of ras 1
LHX8 LIM homeobox 8
LINC00486 long intergenic non-protein coding RNA 486
LINC00570 long intergenic non-protein coding RNA 570
LOC284648 uncharacterized LOC284648
LOC729683 uncharacterized LOC729683
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LTB lymphotoxin beta (TNF superfamily, member 3)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MIR1538 microRNA 1538
MIR3973 microRNA 3973
MIR4322 microRNA 4322
MIR4505 microRNA 4505
MIR4734 microRNA 4734
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MSL1 male-specific lethal 1 homolog (Drosophila)
MSX1 msh homeobox 1
MTMR1 myotubularin related protein 1
NAV1 neuron navigator 1
NCS1 neuronal calcium sensor 1
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NEK6 NIMA-related kinase 6
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14
OPTN optineurin
ORAI1 ORAI calcium release-activated calcium modulator 1
PACS1 phosphofurin acidic cluster sorting protein 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PARK7 parkinson protein 7
PARP8 poly (ADP-ribose) polymerase family, member 8
PAX3 paired box 3
PDZD2 PDZ domain containing 2
PEA15 phosphoprotein enriched in astrocytes 15
PFN1 profilin 1
PI3 peptidase inhibitor 3, skin-derived
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PNKD paroxysmal nonkinesigenic dyskinesia
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PPP6C protein phosphatase 6, catalytic subunit
PRDM2 PR domain containing 2, with ZNF domain
PRR5L proline rich 5 like
PTPRR protein tyrosine phosphatase, receptor type, R
RAB10 RAB10, member RAS oncogene family
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RBP5 retinol binding protein 5, cellular
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELT RELT tumor necrosis factor receptor
RIPK2 receptor-interacting serine-threonine kinase 2
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SEC24A SEC24 family member A
SETD5 SET domain containing 5
SH2B3 SH2B adaptor protein 3
SH3GLB1 SH3-domain GRB2-like endophilin B1
SLC12A8 solute carrier family 12, member 8
SLC30A2 solute carrier family 30 (zinc transporter), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOWAHB sosondowah ankyrin repeat domain family member B
SOX13 SRY (sex determining region Y)-box 13
SPATS2 spermatogenesis associated, serine-rich 2
STX17 syntaxin 17
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae)
SYNPO synaptopodin
SYT1 synaptotagmin I
TDRD10 tudor domain containing 10
THADA thyroid adenoma associated
TLX1 T-cell leukemia homeobox 1
TM4SF1 transmembrane 4 L six family member 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNK2 tyrosine kinase, non-receptor, 2
TOM1L1 target of myb1 (chicken)-like 1
TOR3A torsin family 3, member A
TRAF3IP3 TRAF3 interacting protein 3
TRPT1 tRNA phosphotransferase 1
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UBL7 ubiquitin-like 7
UCK2 uridine-cytidine kinase 2
UNC13B unc-13 homolog B (C. elegans)
VANGL2 VANGL planar cell polarity protein 2
VASH2 vasohibin 2
VCAN versican
VIM vimentin
VRTN vertebrae development associated
ZBTB1 zinc finger and BTB domain containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZFP91 ZFP91 zinc finger protein
ZFP91-CNTF ZFP91-CNTF readthrough (NMD candidate)
ZMYND15 zinc finger, MYND-type containing 15
ZNF436-AS1 ZNF436 antisense RNA 1
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase