| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/RELA_DN.V1_UP |
| Similar Terms | |
| Downloads & Tools |
288 genes differentially expressed following the RELA_DN.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| APOB | apolipoprotein B |
| ATF3 | activating transcription factor 3 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| ATP5C1 | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| BCO1 | beta-carotene oxygenase 1 |
| BIN1 | bridging integrator 1 |
| BPNT1 | 3'(2'), 5'-bisphosphate nucleotidase 1 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD38 | CD38 molecule |
| CDHR5 | cadherin-related family member 5 |
| CDK5R2 | cyclin-dependent kinase 5, regulatory subunit 2 (p39) |
| CDKN2B | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
| CELP | carboxyl ester lipase pseudogene |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CLDN15 | claudin 15 |
| CLK1 | CDC-like kinase 1 |
| CRB1 | crumbs family member 1, photoreceptor morphogenesis associated |
| CRYGA | crystallin, gamma A |
| CST5 | cystatin D |
| CTF1 | cardiotrophin 1 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DEFB1 | defensin, beta 1 |
| DGKI | diacylglycerol kinase, iota |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 |
| DNMT3L | DNA (cytosine-5-)-methyltransferase 3-like |
| DUSP8 | dual specificity phosphatase 8 |
| DYSF | dysferlin |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| ESM1 | endothelial cell-specific molecule 1 |
| ETFDH | electron-transferring-flavoprotein dehydrogenase |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| F9 | coagulation factor IX |
| FGF17 | fibroblast growth factor 17 |
| FGF2 | fibroblast growth factor 2 (basic) |
| FHL5 | four and a half LIM domains 5 |
| FLRT1 | fibronectin leucine rich transmembrane protein 1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL1 | FOS-like antigen 1 |
| FXYD7 | FXYD domain containing ion transport regulator 7 |
| FZD9 | frizzled class receptor 9 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GAS7 | growth arrest-specific 7 |
| GHRH | growth hormone releasing hormone |
| GJB1 | gap junction protein, beta 1, 32kDa |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GLYAT | glycine-N-acyltransferase |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GPR183 | G protein-coupled receptor 183 |
| GPR85 | G protein-coupled receptor 85 |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) |
| GRAP | GRB2-related adaptor protein |
| HOOK1 | hook microtubule-tethering protein 1 |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IL1B | interleukin 1, beta |
| INE1 | inactivation escape 1 (non-protein coding) |
| INTS6 | integrator complex subunit 6 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KCNA1 | potassium channel, voltage gated shaker related subfamily A, member 1 |
| KCNC4 | potassium channel, voltage gated Shaw related subfamily C, member 4 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 |
| KCNQ4 | potassium channel, voltage gated KQT-like subfamily Q, member 4 |
| KDM5D | lysine (K)-specific demethylase 5D |
| KLF10 | Kruppel-like factor 10 |
| KLF6 | Kruppel-like factor 6 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LAMC2 | laminin, gamma 2 |
| LGMN | legumain |
| LHCGR | luteinizing hormone/choriogonadotropin receptor |
| LILRP2 | leukocyte immunoglobulin-like receptor pseudogene 2 |
| LMO7 | LIM domain 7 |
| MAGEB4 | melanoma antigen family B4 |
| MAK | male germ cell-associated kinase |
| MC3R | melanocortin 3 receptor |
| MEP1B | meprin A, beta |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) |
| MTMR11 | myotubularin related protein 11 |
| MYBPC3 | myosin binding protein C, cardiac |
| NFIC | nuclear factor I/C (CCAAT-binding transcription factor) |
| NLK | nemo-like kinase |
| NOL4 | nucleolar protein 4 |
| NOVA1 | neuro-oncological ventral antigen 1 |
| NTM | neurotrimin |
| NTS | neurotensin |
| P2RY10 | purinergic receptor P2Y, G-protein coupled, 10 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PDE5A | phosphodiesterase 5A, cGMP-specific |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PEX6 | peroxisomal biogenesis factor 6 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PIP | prolactin-induced protein |
| PNLIPRP1 | pancreatic lipase-related protein 1 |
| PODXL2 | podocalyxin-like 2 |
| PPAN | peter pan homolog (Drosophila) |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRDM11 | PR domain containing 11 |
| PRKG1 | protein kinase, cGMP-dependent, type I |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF25 | ring finger protein 25 |
| RNF39 | ring finger protein 39 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SCG5 | secretogranin V |
| SIRPB1 | signal-regulatory protein beta 1 |
| SIRT4 | sirtuin 4 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SNAI1 | snail family zinc finger 1 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa |
| SRCAP | Snf2-related CREBBP activator protein |
| TANK | TRAF family member-associated NFKB activator |
| TEX14 | testis expressed 14 |
| THBD | thrombomodulin |
| TLX1 | T-cell leukemia homeobox 1 |
| TNC | tenascin C |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 |
| TPMT | thiopurine S-methyltransferase |
| TREX1 | three prime repair exonuclease 1 |
| TRIM38 | tripartite motif containing 38 |
| ULBP2 | UL16 binding protein 2 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| VEGFA | vascular endothelial growth factor A |
| VEGFB | vascular endothelial growth factor B |
| WASL | Wiskott-Aldrich syndrome-like |
| WRNIP1 | Werner helicase interacting protein 1 |
| XCL1 | chemokine (C motif) ligand 1 |
| ZFP36 | ZFP36 ring finger protein |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZFP37 | ZFP37 zinc finger protein |
| ZNF165 | zinc finger protein 165 |
| ZNF222 | zinc finger protein 222 |
| ZNF286A | zinc finger protein 286A |
| ZNF324 | zinc finger protein 324 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| Symbol | Name |
|---|---|
| ADGRE1 | adhesion G protein-coupled receptor E1 |
| ADRA1D | adrenoceptor alpha 1D |
| APCS | amyloid P component, serum |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| AVP | arginine vasopressin |
| BMPR1B | bone morphogenetic protein receptor, type IB |
| C1ORF21 | chromosome 1 open reading frame 21 |
| C5AR2 | complement component 5a receptor 2 |
| C7 | complement component 7 |
| CA9 | carbonic anhydrase IX |
| CALY | calcyon neuron-specific vesicular protein |
| CAPN9 | calpain 9 |
| CASC5 | cancer susceptibility candidate 5 |
| CCNK | cyclin K |
| CD247 | CD247 molecule |
| CD53 | CD53 molecule |
| CDON | cell adhesion associated, oncogene regulated |
| CH25H | cholesterol 25-hydroxylase |
| CHIT1 | chitinase 1 (chitotriosidase) |
| CLCN1 | chloride channel, voltage-sensitive 1 |
| CLDN6 | claudin 6 |
| CRISP2 | cysteine-rich secretory protein 2 |
| CST1 | cystatin SN |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 |
| CXCR3 | chemokine (C-X-C motif) receptor 3 |
| CYTIP | cytohesin 1 interacting protein |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DSG3 | desmoglein 3 |
| DUOX2 | dual oxidase 2 |
| ECEL1 | endothelin converting enzyme-like 1 |
| EGFL6 | EGF-like-domain, multiple 6 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| F13B | coagulation factor XIII, B polypeptide |
| FMO5 | flavin containing monooxygenase 5 |
| FTCD | formimidoyltransferase cyclodeaminase |
| GAGE3 | G antigen 3 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GDF5 | growth differentiation factor 5 |
| GNMT | glycine N-methyltransferase |
| GNRH2 | gonadotropin-releasing hormone 2 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR3 | G protein-coupled receptor 3 |
| GSTM1 | glutathione S-transferase mu 1 |
| HAS1 | hyaluronan synthase 1 |
| HDAC9 | histone deacetylase 9 |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H4B | histone cluster 1, H4b |
| HIST1H4L | histone cluster 1, H4l |
| HOXD3 | homeobox D3 |
| HRC | histidine rich calcium binding protein |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| HTR3B | 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic |
| IDUA | iduronidase, alpha-L- |
| IL17RB | interleukin 17 receptor B |
| IL2RG | interleukin 2 receptor, gamma |
| IL7R | interleukin 7 receptor |
| KCNA2 | potassium channel, voltage gated shaker related subfamily A, member 2 |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KLF8 | Kruppel-like factor 8 |
| KLK11 | kallikrein-related peptidase 11 |
| KLK7 | kallikrein-related peptidase 7 |
| KRT1 | keratin 1, type II |
| L1CAM | L1 cell adhesion molecule |
| LCE2B | late cornified envelope 2B |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LUZP4 | leucine zipper protein 4 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MECOM | MDS1 and EVI1 complex locus |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MST1R | macrophage stimulating 1 receptor |
| MUC4 | mucin 4, cell surface associated |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| MYOM1 | myomesin 1 |
| MYOM2 | myomesin 2 |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NFE2 | nuclear factor, erythroid 2 |
| NNAT | neuronatin |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| NPY4R | neuropeptide Y receptor Y4 |
| NRXN3 | neurexin 3 |
| OR10H1 | olfactory receptor, family 10, subfamily H, member 1 |
| OXT | oxytocin/neurophysin I prepropeptide |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PC | pyruvate carboxylase |
| PKLR | pyruvate kinase, liver and RBC |
| PLA2G10 | phospholipase A2, group X |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PRSS8 | protease, serine, 8 |
| PSCA | prostate stem cell antigen |
| PSD | pleckstrin and Sec7 domain containing |
| PTN | pleiotrophin |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| RAB30 | RAB30, member RAS oncogene family |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RASA3 | RAS p21 protein activator 3 |
| RBBP9 | retinoblastoma binding protein 9 |
| RBMXL2 | RNA binding motif protein, X-linked-like 2 |
| RBP1 | retinol binding protein 1, cellular |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RHOH | ras homolog family member H |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| SRPX2 | sushi-repeat containing protein, X-linked 2 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STAG3 | stromal antigen 3 |
| TACR3 | tachykinin receptor 3 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TBX5 | T-box 5 |
| TEF | thyrotrophic embryonic factor |
| TFDP3 | transcription factor Dp family, member 3 |
| TFEC | transcription factor EC |
| TFF1 | trefoil factor 1 |
| TMEM176A | transmembrane protein 176A |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNNI3 | troponin I type 3 (cardiac) |
| TPTE | transmembrane phosphatase with tensin homology |
| TRAF1 | TNF receptor-associated factor 1 |
| TXNRD2 | thioredoxin reductase 2 |
| UTS2 | urotensin 2 |
| VEGFC | vascular endothelial growth factor C |
| WNT2 | wingless-type MMTV integration site family member 2 |
| XPNPEP2 | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound |
