RERF-LC-MS Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

179 genes with high or low expression in RERF-LC-MS relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
SELE selectin E 2.47808
GBX2 gastrulation brain homeobox 2 2.22509
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 2.13341
SPINK4 serine peptidase inhibitor, Kazal type 4 2.12594
TCF21 transcription factor 21 2.10406
GLA galactosidase, alpha 2.09573
SP4 Sp4 transcription factor 2.07558
MAGEA10 melanoma antigen family A10 2.03372
ATG12 autophagy related 12 2.0132
LCN1 lipocalin 1 2.0019
CLC Charcot-Leyden crystal galectin 1.99187
CGA glycoprotein hormones, alpha polypeptide 1.98917
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 1.98132
HOXA1 homeobox A1 1.95407
HOXA4 homeobox A4 1.94119
CD34 CD34 molecule 1.94073
ANGPT2 angiopoietin 2 1.90618
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 1.89342
TRPA1 transient receptor potential cation channel, subfamily A, member 1 1.88234
DIO2 deiodinase, iodothyronine, type II 1.84092
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 1.83077
DPEP3 dipeptidase 3 1.79232
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.7849
DIO3 deiodinase, iodothyronine, type III 1.77548
SELL selectin L 1.77492
MID1 midline 1 1.76802
NRCAM neuronal cell adhesion molecule 1.72519
DIRAS3 DIRAS family, GTP-binding RAS-like 3 1.72492
HOXA5 homeobox A5 1.70867
PF4 platelet factor 4 1.70174
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) 1.69646
SRP19 signal recognition particle 19kDa 1.69474
COL4A6 collagen, type IV, alpha 6 1.67862
MPO myeloperoxidase 1.65514
F5 coagulation factor V (proaccelerin, labile factor) 1.63897
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 1.63872
RND2 Rho family GTPase 2 1.63178
NR5A2 nuclear receptor subfamily 5, group A, member 2 1.61824
MAGEA4 melanoma antigen family A4 1.61025
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.60265
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.60033
SAGE1 sarcoma antigen 1 1.5829
S100A3 S100 calcium binding protein A3 1.57317
NR4A3 nuclear receptor subfamily 4, group A, member 3 1.57212
PHKA1 phosphorylase kinase, alpha 1 (muscle) 1.56986
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 1.56214
GCLM glutamate-cysteine ligase, modifier subunit 1.55725
GAGE3 G antigen 3 1.55095
DOLK dolichol kinase 1.54779
GAGE7 G antigen 7 1.53025
BMP6 bone morphogenetic protein 6 1.51557
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.51211
EPHA5 EPH receptor A5 1.50267
SMOX spermine oxidase 1.49501
PDZRN4 PDZ domain containing ring finger 4 1.49441
CRLF2 cytokine receptor-like factor 2 1.49413
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 1.49252
ELANE elastase, neutrophil expressed 1.49114
ACOT9 acyl-CoA thioesterase 9 1.49005
HHIPL2 HHIP-like 2 1.48585
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 1.4855
HOXA2 homeobox A2 1.47765
LRRC6 leucine rich repeat containing 6 1.47628
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 1.46932
HMOX1 heme oxygenase 1 1.4546
NOVA1 neuro-oncological ventral antigen 1 1.45373
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.44291
B9D1 B9 protein domain 1 1.44179
HCCS holocytochrome c synthase 1.44047
PDGFRL platelet-derived growth factor receptor-like 1.43923
TEK TEK tyrosine kinase, endothelial 1.43561
PDE4B phosphodiesterase 4B, cAMP-specific 1.43441
FGG fibrinogen gamma chain 1.4291
LOC284244 uncharacterized LOC284244 1.41751

low expression

Symbol Name Standardized Value
ZGPAT zinc finger, CCCH-type with G patch domain -3.28131
HBE1 hemoglobin, epsilon 1 -2.81032
HRH4 histamine receptor H4 -2.79093
MRPL2 mitochondrial ribosomal protein L2 -2.66925
G6PC glucose-6-phosphatase, catalytic subunit -2.62179
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 -2.50929
NOL12 nucleolar protein 12 -2.48434
GAD1 glutamate decarboxylase 1 (brain, 67kDa) -2.45618
ANGPTL2 angiopoietin-like 2 -2.4293
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime -2.31157
PVRL3 poliovirus receptor-related 3 -2.28578
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -2.21123
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -2.16199
LTB4R leukotriene B4 receptor -2.11051
CCNK cyclin K -2.09447
DSG1 desmoglein 1 -2.07589
PISD phosphatidylserine decarboxylase -2.02104
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 -1.92826
GIMAP6 GTPase, IMAP family member 6 -1.91683
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 -1.91124
MYH2 myosin, heavy chain 2, skeletal muscle, adult -1.8744
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -1.86556
MPPED2 metallophosphoesterase domain containing 2 -1.86331
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing -1.86277
NOVA2 neuro-oncological ventral antigen 2 -1.84011
FLJ21369 uncharacterized protein FLJ21369 -1.83888
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 -1.81058
PARD6B par-6 family cell polarity regulator beta -1.79516
HAVCR1 hepatitis A virus cellular receptor 1 -1.76717
PRPF3 pre-mRNA processing factor 3 -1.76607
ANKRD26 ankyrin repeat domain 26 -1.75921
TRIM3 tripartite motif containing 3 -1.753
FZD8 frizzled class receptor 8 -1.74915
CCL16 chemokine (C-C motif) ligand 16 -1.74884
LOC157562 uncharacterized LOC157562 -1.74521
ITPKB inositol-trisphosphate 3-kinase B -1.72003
OPCML opioid binding protein/cell adhesion molecule-like -1.70603
PDYN prodynorphin -1.70361
NR3C2 nuclear receptor subfamily 3, group C, member 2 -1.69782
NRXN1 neurexin 1 -1.69016
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 -1.6696
SPRR3 small proline-rich protein 3 -1.66868
STK11 serine/threonine kinase 11 -1.66684
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) -1.66588
PLCG1 phospholipase C, gamma 1 -1.66155
RBBP9 retinoblastoma binding protein 9 -1.65966
RAD52 RAD52 homolog (S. cerevisiae) -1.65771
NEUROG2 neurogenin 2 -1.65362
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -1.6488
NPY neuropeptide Y -1.64713
BTBD7 BTB (POZ) domain containing 7 -1.63624
SULT1A3 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 -1.6345
ACBD4 acyl-CoA binding domain containing 4 -1.62262
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma -1.62195
LPAR2 lysophosphatidic acid receptor 2 -1.61902
HRASLS2 HRAS-like suppressor 2 -1.61442
VNN1 vanin 1 -1.59765
HIST1H3F histone cluster 1, H3f -1.59753
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 -1.59656
IL37 interleukin 37 -1.59198
BCL2L11 BCL2-like 11 (apoptosis facilitator) -1.58435
EHF ets homologous factor -1.58382
AHSP alpha hemoglobin stabilizing protein -1.58339
XIST X inactive specific transcript (non-protein coding) -1.5828
SCRG1 stimulator of chondrogenesis 1 -1.58188
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) -1.56914
METTL16 methyltransferase like 16 -1.56548
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -1.55752
KLRC4 killer cell lectin-like receptor subfamily C, member 4 -1.55141
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 -1.53505
TIMP4 TIMP metallopeptidase inhibitor 4 -1.53499
BAGE B melanoma antigen -1.53008
PCYT1B phosphate cytidylyltransferase 1, choline, beta -1.52641
RGS12 regulator of G-protein signaling 12 -1.51871
KRT33A keratin 33A, type I -1.51245
CLIC5 chloride intracellular channel 5 -1.51199
CCL8 chemokine (C-C motif) ligand 8 -1.50874
NIPSNAP3B nipsnap homolog 3B (C. elegans) -1.50864
DYM dymeclin -1.50249
GHRHR growth hormone releasing hormone receptor -1.50218
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) -1.50186
WNK1 WNK lysine deficient protein kinase 1 -1.50086
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 -1.49356
STATH statherin -1.49224
LATS1 large tumor suppressor kinase 1 -1.48822
SENP7 SUMO1/sentrin specific peptidase 7 -1.4875
PCDHA3 protocadherin alpha 3 -1.48559
SCAND2P SCAN domain containing 2 pseudogene -1.48444
PSG5 pregnancy specific beta-1-glycoprotein 5 -1.48385
EPHA3 EPH receptor A3 -1.48384
DIDO1 death inducer-obliterator 1 -1.48081
MMP8 matrix metallopeptidase 8 -1.48066
LY6D lymphocyte antigen 6 complex, locus D -1.4714
KLHDC3 kelch domain containing 3 -1.46686
SPP2 secreted phosphoprotein 2, 24kDa -1.46466
STAR steroidogenic acute regulatory protein -1.45595
RNF17 ring finger protein 17 -1.44888
RAD9A RAD9 homolog A (S. pombe) -1.44444
GPR88 G protein-coupled receptor 88 -1.44291
NPY5R neuropeptide Y receptor Y5 -1.44022
IVD isovaleryl-CoA dehydrogenase -1.43635
TAAR2 trace amine associated receptor 2 -1.43298
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 -1.4307
JRKL JRK-like -1.42962
TRPV1 transient receptor potential cation channel, subfamily V, member 1 -1.41616