REST Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description RE1-silencing transcription factor|This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described [provided by RefSeq, Jul 2010] (NCBI Entrez Gene Database, 5978)
External Link https://ncbi.nlm.nih.gov/gene/5978
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Genes

498 genes differentially expressed following the REST gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
GNAS GNAS complex locus 0.0173773
L1CAM L1 cell adhesion molecule 0.0163916
PTK2 protein tyrosine kinase 2 0.0145506
CPE carboxypeptidase E 0.0131488
NPY1R neuropeptide Y receptor Y1 0.0128904
TFF1 trefoil factor 1 0.012744
BEX1 brain expressed, X-linked 1 0.0123516
RGS5 regulator of G-protein signaling 5 0.0117186
CHGB chromogranin B 0.0117108
SEPP1 selenoprotein P, plasma, 1 0.0115017
ACKR3 atypical chemokine receptor 3 0.0108223
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0108179
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.0107061
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.01022
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.010119
OXA1L oxidase (cytochrome c) assembly 1-like 0.00986406
AQP1 aquaporin 1 (Colton blood group) 0.00984844
PEG3 paternally expressed 3 0.00984068
NPIPB3 nuclear pore complex interacting protein family, member B3 0.0093639
FGF13 fibroblast growth factor 13 0.00911428
HHEX hematopoietically expressed homeobox 0.00887847
GPX1 glutathione peroxidase 1 0.0087139
CADM1 cell adhesion molecule 1 0.0086737
CPVL carboxypeptidase, vitellogenic-like 0.00866174
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00856199
PAN2 PAN2 poly(A) specific ribonuclease subunit 0.00844467
GOLGA8A golgin A8 family, member A 0.00840859
HBB hemoglobin, beta 0.00840109
GREM1 gremlin 1, DAN family BMP antagonist 0.00834497
MAL mal, T-cell differentiation protein 0.00832041
FCGBP Fc fragment of IgG binding protein 0.00831736
RNASET2 ribonuclease T2 0.00830684
LMO2 LIM domain only 2 (rhombotin-like 1) 0.0082941
ANOS1 anosmin 1 0.00823854
KYNU kynureninase 0.0081737
ITM2C integral membrane protein 2C 0.00811096
CLU clusterin 0.0081
ANXA3 annexin A3 0.00796751
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.00791537
VCL vinculin 0.00789425
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.00788347
OLFM1 olfactomedin 1 0.00782722
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.00766437
PSCA prostate stem cell antigen 0.0076504
SAMD4A sterile alpha motif domain containing 4A 0.00758552
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00758322
CXCL12 chemokine (C-X-C motif) ligand 12 0.00756169
FXYD6 FXYD domain containing ion transport regulator 6 0.00755888
DLK1 delta-like 1 homolog (Drosophila) 0.00751545
FN1 fibronectin 1 0.0074449
IFRD2 interferon-related developmental regulator 2 0.00743768
GPX3 glutathione peroxidase 3 0.00741819
ASS1 argininosuccinate synthase 1 0.00737933
FABP4 fatty acid binding protein 4, adipocyte 0.00737389
IGFBP5 insulin-like growth factor binding protein 5 0.00735081
SOX11 SRY (sex determining region Y)-box 11 0.00728143
CTSC cathepsin C 0.00721634
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.00714415
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00713384
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.00711221
COL9A3 collagen, type IX, alpha 3 0.00709123
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00708585
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00704332
PPIF peptidylprolyl isomerase F 0.00698365
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.00694558
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.006924
S100P S100 calcium binding protein P 0.00692173
PIGP phosphatidylinositol glycan anchor biosynthesis, class P 0.00684943
APOLD1 apolipoprotein L domain containing 1 0.00684048
CYTH1 cytohesin 1 0.0068141
ZNF721 zinc finger protein 721 0.0067808
SHTN1 shootin 1 0.0067791
MT1F metallothionein 1F 0.0067628
IFI27 interferon, alpha-inducible protein 27 0.00675102
STMN2 stathmin 2 0.00673757
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.00670437
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.00670211
CA2 carbonic anhydrase II 0.00669096
PDK4 pyruvate dehydrogenase kinase, isozyme 4 0.00668949
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00668222
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00668027
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00665672
JAM2 junctional adhesion molecule 2 0.00657377
KDM5D lysine (K)-specific demethylase 5D 0.00654234
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.00649612
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00649092
NPTX2 neuronal pentraxin II 0.00648084
RET ret proto-oncogene 0.00643544
KRT8 keratin 8, type II 0.00640479
MAB21L2 mab-21-like 2 (C. elegans) 0.00640126
ADIRF adipogenesis regulatory factor 0.00633821
NEBL nebulette 0.0063347
METTL7A methyltransferase like 7A 0.00632817
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00629445
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.0062915
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.00626228
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.00625404
GREB1 growth regulation by estrogen in breast cancer 1 0.00621012
MSLN mesothelin 0.00618245
PRDX2 peroxiredoxin 2 0.00618143
HSPA1A heat shock 70kDa protein 1A 0.00614477
MARCKS myristoylated alanine-rich protein kinase C substrate 0.00610961
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.00607845
SYNGR3 synaptogyrin 3 0.0060447
NEFH neurofilament, heavy polypeptide 0.00604448
GOLGA8H golgin A8 family, member H 0.00604443
PLVAP plasmalemma vesicle associated protein 0.00603578
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00603147
PRNP prion protein 0.00600005
CCNG1 cyclin G1 0.00597973
COG7 component of oligomeric golgi complex 7 0.00597391
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 0.00597044
TXNL4A thioredoxin-like 4A 0.00596525
SFRP1 secreted frizzled-related protein 1 0.00595564
DUOX2 dual oxidase 2 0.00594318
ZNF160 zinc finger protein 160 0.00593346
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.00592452
F3 coagulation factor III (thromboplastin, tissue factor) 0.00592204
PPARG peroxisome proliferator-activated receptor gamma 0.00591178
LITAF lipopolysaccharide-induced TNF factor 0.00590567
LXN latexin 0.00589505
SH3BP4 SH3-domain binding protein 4 0.00588519
CSRP2 cysteine and glycine-rich protein 2 0.00588421
OPHN1 oligophrenin 1 0.00588234
ERGIC3 ERGIC and golgi 3 0.00588137
DMAC2L distal membrane arm assembly component 2 like 0.00586747
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00586554
EIF3G eukaryotic translation initiation factor 3, subunit G 0.00586554
TSPAN8 tetraspanin 8 0.00585703
TM9SF3 transmembrane 9 superfamily member 3 0.00585208
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00584726
FHL1 four and a half LIM domains 1 0.00583765
IGF1 insulin-like growth factor 1 (somatomedin C) 0.00581585
PEBP1 phosphatidylethanolamine binding protein 1 0.00580688
PBX1 pre-B-cell leukemia homeobox 1 0.00580293
MEIS1 Meis homeobox 1 0.00579953
DAXX death-domain associated protein 0.00577314
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00577074
EGR2 early growth response 2 0.00575423
TMEM176B transmembrane protein 176B 0.00575263
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.00570866
PUF60 poly-U binding splicing factor 60KDa 0.00567117
TJP2 tight junction protein 2 0.00566808
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.00566175
C6ORF48 chromosome 6 open reading frame 48 0.00561314
PROM1 prominin 1 0.005605
OLFML2A olfactomedin-like 2A 0.00560314
SLC35G2 solute carrier family 35, member G2 0.00558738
NID1 nidogen 1 0.00557797
ADGRG6 adhesion G protein-coupled receptor G6 0.0055501
MECOM MDS1 and EVI1 complex locus 0.00554826
AOX1 aldehyde oxidase 1 0.00554013
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.00553108
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.00552872
HSPB8 heat shock 22kDa protein 8 0.00552199
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.00551662
GRHPR glyoxylate reductase/hydroxypyruvate reductase 0.00550471
SOWAHC sosondowah ankyrin repeat domain family member C 0.00549579
SNAP25 synaptosomal-associated protein, 25kDa 0.0054951
BHLHE41 basic helix-loop-helix family, member e41 0.00548766
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00544175
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.0054244
A2M alpha-2-macroglobulin 0.00542383
GMDS GDP-mannose 4,6-dehydratase 0.00542067
PLLP plasmolipin 0.00541311
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00540497
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa 0.00540195
TIMP3 TIMP metallopeptidase inhibitor 3 0.00539177
MEN1 multiple endocrine neoplasia I 0.0053816
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.00537501
ADCY1 adenylate cyclase 1 (brain) 0.00537391
RTN1 reticulon 1 0.00537377
DENND3 DENN/MADD domain containing 3 0.0053719
KARS1 lysyl-tRNA synthetase 1 0.00537144
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.00536371
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00536317
MATN2 matrilin 2 0.00535494
MUC2 mucin 2, oligomeric mucus/gel-forming 0.00534762
PLP1 proteolipid protein 1 0.00533232
SASH1 SAM and SH3 domain containing 1 0.00533082
LAMB1 laminin, beta 1 0.00531883
CYBA cytochrome b-245, alpha polypeptide 0.00531365
VWF von Willebrand factor 0.00529969
AHCY adenosylhomocysteinase 0.0052965
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00529579
CLEC3B C-type lectin domain family 3, member B 0.00529452
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.00528317
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00527858
MRPL19 mitochondrial ribosomal protein L19 0.00527214
NKX2-2 NK2 homeobox 2 0.0052716
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.00526005
COX5A cytochrome c oxidase subunit Va 0.00525842
TAC1 tachykinin, precursor 1 0.00525418
TRIM8 tripartite motif containing 8 0.00525381
ELL2 elongation factor, RNA polymerase II, 2 0.00525276
DNASE1L3 deoxyribonuclease I-like 3 0.00525198
PRR11 proline rich 11 0.00524891
INSR insulin receptor 0.00523194
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.00522445
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.00522365
CDH5 cadherin 5, type 2 (vascular endothelium) 0.00517708
NDN necdin, melanoma antigen (MAGE) family member 0.00517288
AMZ2 archaelysin family metallopeptidase 2 0.00516725
DST dystonin 0.00516694
CAVIN2 caveolae associated protein 2 0.00516347
ACAT1 acetyl-CoA acetyltransferase 1 0.00515974
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.0051449
KIF2C kinesin family member 2C 0.00514396
MCF2L MCF.2 cell line derived transforming sequence-like 0.00513857
SEPTIN4 septin 4 0.00510282
MEG3 maternally expressed 3 (non-protein coding) 0.00509906
TMEM243 transmembrane protein 243, mitochondrial 0.00508417
ANXA10 annexin A10 0.00506624
MTUS1 microtubule associated tumor suppressor 1 0.00506345
SPARCL1 SPARC-like 1 (hevin) 0.00505404
TSPAN1 tetraspanin 1 0.00505287
XPO7 exportin 7 0.00504873
UQCRB ubiquinol-cytochrome c reductase binding protein 0.00504764
FGFR1 fibroblast growth factor receptor 1 0.00504116
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 0.00502727
STON1 stonin 1 0.00502493
GPC3 glypican 3 0.00500871
RBM34 RNA binding motif protein 34 0.00500624
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.00500273
ACACB acetyl-CoA carboxylase beta 0.00499391
LGALS4 lectin, galactoside-binding, soluble, 4 0.00499097
DDR2 discoidin domain receptor tyrosine kinase 2 0.00499047
TUBB2B tubulin, beta 2B class IIb 0.00498331
INA internexin neuronal intermediate filament protein, alpha 0.0049766
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00497361
CYC1 cytochrome c-1 0.00496794
HYAL1 hyaluronoglucosaminidase 1 0.00496389
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00495963
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.00495937
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) 0.00495824
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00495355
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.00492953
ACD adrenocortical dysplasia homolog (mouse) 0.00492231
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.00492091
TSC22D2 TSC22 domain family, member 2 0.00491824
SST somatostatin 0.00491406
DAAM2 dishevelled associated activator of morphogenesis 2 0.00491263
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.00491141
ADRA2A adrenoceptor alpha 2A 0.00491079
SELE selectin E 0.00490987
KLF6 Kruppel-like factor 6 0.00490738
LDB2 LIM domain binding 2 0.00490342
WFDC1 WAP four-disulfide core domain 1 0.00490218
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.00490114
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00489727

decreased expression

Symbol Name Standardized Value
LTF lactotransferrin -0.0145775
SSBP2 single-stranded DNA binding protein 2 -0.0129234
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.0126707
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.0114437
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.0108031
MYB v-myb avian myeloblastosis viral oncogene homolog -0.0107859
SCGB1D2 secretoglobin, family 1D, member 2 -0.0107741
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.0105997
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.00995868
MMP7 matrix metallopeptidase 7 -0.0096262
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00947881
STK26 serine/threonine protein kinase 26 -0.00947363
PDHX pyruvate dehydrogenase complex, component X -0.00902195
CA12 carbonic anhydrase XII -0.00886718
S100A9 S100 calcium binding protein A9 -0.00883622
CTSZ cathepsin Z -0.00865376
DPYD dihydropyrimidine dehydrogenase -0.00859643
KRT15 keratin 15, type I -0.00857822
TPSAB1 tryptase alpha/beta 1 -0.00842185
TMC5 transmembrane channel-like 5 -0.00832994
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00822273
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -0.00816742
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0081501
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 -0.00799383
ELANE elastase, neutrophil expressed -0.00796133
LTBP1 latent transforming growth factor beta binding protein 1 -0.00793785
XIC X chromosome inactivation center -0.00792135
WIF1 WNT inhibitory factor 1 -0.00785848
POSTN periostin, osteoblast specific factor -0.0076201
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00760622
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00738988
SCGB2A2 secretoglobin, family 2A, member 2 -0.00738919
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00735664
NIBAN1 niban apoptosis regulator 1 -0.00731664
CCL5 chemokine (C-C motif) ligand 5 -0.00717717
TARP TCR gamma alternate reading frame protein -0.00715453
DSP desmoplakin -0.00713419
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.00713112
LMNB1 lamin B1 -0.00711687
EREG epiregulin -0.00708235
ACSL5 acyl-CoA synthetase long-chain family member 5 -0.0070749
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -0.00704162
RCAN1 regulator of calcineurin 1 -0.00703641
AZU1 azurocidin 1 -0.00697349
NOTCH2 notch 2 -0.00696379
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.00695037
LEF1 lymphoid enhancer-binding factor 1 -0.00691687
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.00688827
MZB1 marginal zone B and B1 cell-specific protein -0.00682289
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -0.00680814
BIK BCL2-interacting killer (apoptosis-inducing) -0.00675943
GLOD4 glyoxalase domain containing 4 -0.00671259
SMYD3 SET and MYND domain containing 3 -0.00669859
JCHAIN joining chain of multimeric IgA and IgM -0.00667732
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00667506
STK38L serine/threonine kinase 38 like -0.00667304
SULF1 sulfatase 1 -0.00661234
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.00660049
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00654218
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.00650132
CD9 CD9 molecule -0.00649502
S100A8 S100 calcium binding protein A8 -0.00648144
IGLL1 immunoglobulin lambda-like polypeptide 1 -0.00645639
PTGES prostaglandin E synthase -0.00644919
SFN stratifin -0.00640253
HMGN4 high mobility group nucleosomal binding domain 4 -0.00639798
KRT14 keratin 14, type I -0.00639186
RAG1 recombination activating gene 1 -0.00636239
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00636168
SPRY2 sprouty homolog 2 (Drosophila) -0.00633967
CIAO3 cytosolic iron-sulfur assembly component 3 -0.0063381
DEPTOR DEP domain containing MTOR-interacting protein -0.0062576
PTPN7 protein tyrosine phosphatase, non-receptor type 7 -0.00625203
IFI30 interferon, gamma-inducible protein 30 -0.00624042
SNX7 sorting nexin 7 -0.00623738
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00620913
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00620721
PRAME preferentially expressed antigen in melanoma -0.00616809
NREP neuronal regeneration related protein -0.00616468
PMM1 phosphomannomutase 1 -0.00616212
ARHGAP26 Rho GTPase activating protein 26 -0.00614758
NUSAP1 nucleolar and spindle associated protein 1 -0.00610984
TPD52L1 tumor protein D52-like 1 -0.00610485
AAMDC adipogenesis associated, Mth938 domain containing -0.00608203
PRTN3 proteinase 3 -0.00602161
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00598506
ELOVL5 ELOVL fatty acid elongase 5 -0.00594534
IL7R interleukin 7 receptor -0.00593972
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.00591901
CST7 cystatin F (leukocystatin) -0.00591486
ANO3 anoctamin 3 -0.00588638
PSPH phosphoserine phosphatase -0.00586867
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00586725
HDAC9 histone deacetylase 9 -0.00586363
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.00581982
PLBD1 phospholipase B domain containing 1 -0.0058157
RAD23B RAD23 homolog B (S. cerevisiae) -0.00578776
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00578463
PRPF4 pre-mRNA processing factor 4 -0.00578163
GLS glutaminase -0.0057605
DLX5 distal-less homeobox 5 -0.00573823
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 -0.00573362
CNN3 calponin 3, acidic -0.00570593
CLEC5A C-type lectin domain family 5, member A -0.00563378
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00560023
SCGB2A1 secretoglobin, family 2A, member 1 -0.0055947
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -0.00555728
ENAH enabled homolog (Drosophila) -0.00553829
HAL histidine ammonia-lyase -0.00548735
APOD apolipoprotein D -0.0054837
ADAM9 ADAM metallopeptidase domain 9 -0.00547852
MSL2 male-specific lethal 2 homolog (Drosophila) -0.00546486
KRT16 keratin 16, type I -0.00544841
GATAD2A GATA zinc finger domain containing 2A -0.00544336
GPNMB glycoprotein (transmembrane) nmb -0.00543333
GADD45A growth arrest and DNA-damage-inducible, alpha -0.00543333
THAP12 THAP domain containing 12 -0.00542881
CD38 CD38 molecule -0.00542668
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00541473
IL7 interleukin 7 -0.00537049
CRYM crystallin, mu -0.00536728
SSBP3 single stranded DNA binding protein 3 -0.00536377
FLOT1 flotillin 1 -0.00533936
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00531642
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00531184
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 -0.00530869
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00529057
S100A12 S100 calcium binding protein A12 -0.00527972
ZDHHC6 zinc finger, DHHC-type containing 6 -0.00527757
AEBP1 AE binding protein 1 -0.00527573
IL2RG interleukin 2 receptor, gamma -0.0052648
MMP9 matrix metallopeptidase 9 -0.00525496
OVGP1 oviductal glycoprotein 1, 120kDa -0.00523963
TCL1B T-cell leukemia/lymphoma 1B -0.00523956
LHFPL2 lipoma HMGIC fusion partner-like 2 -0.0052248
NT5E 5'-nucleotidase, ecto (CD73) -0.00519619
TSPOAP1 TSPO associated protein 1 -0.00518798
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) -0.00518549
MTCL1 microtubule crosslinking factor 1 -0.00514409
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00514118
RSF1 remodeling and spacing factor 1 -0.00511612
ZBTB18 zinc finger and BTB domain containing 18 -0.00509998
PITX3 paired-like homeodomain 3 -0.00509588
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00509523
BCAT1 branched chain amino-acid transaminase 1, cytosolic -0.00509404
H1-0 H1.0 linker histone -0.00509404
CTSG cathepsin G -0.00509354
HTRA1 HtrA serine peptidase 1 -0.00507842
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00506871
HOXC10 homeobox C10 -0.00506507
EPHB6 EPH receptor B6 -0.00505932
NKX3-1 NK3 homeobox 1 -0.00504127
FAM3C family with sequence similarity 3, member C -0.00504083
KLK11 kallikrein-related peptidase 11 -0.00501263
DPEP1 dipeptidase 1 (renal) -0.00501244
SKI SKI proto-oncogene -0.00500747
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B -0.00498369
ALOX5 arachidonate 5-lipoxygenase -0.00497945
MLPH melanophilin -0.00496958
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) -0.00495775
ARL4A ADP-ribosylation factor-like 4A -0.00494632
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -0.00494157
JMJD6 jumonji domain containing 6 -0.00493519
YBX3 Y box binding protein 3 -0.00492844
HAS2 hyaluronan synthase 2 -0.00492049
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) -0.00491727
MPO myeloperoxidase -0.00491019
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -0.00489242
PTK7 protein tyrosine kinase 7 (inactive) -0.00488959
CYBB cytochrome b-245, beta polypeptide -0.00487488
F12 coagulation factor XII (Hageman factor) -0.00485705
CD84 CD84 molecule -0.00485084
SRGN serglycin -0.00484868
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.0048384
TXNIP thioredoxin interacting protein -0.00482475
APMAP adipocyte plasma membrane associated protein -0.00481804
CCL20 chemokine (C-C motif) ligand 20 -0.00481266
NAV3 neuron navigator 3 -0.00480621
MAOA monoamine oxidase A -0.00479474
RAB8A RAB8A, member RAS oncogene family -0.00479089
NDP Norrie disease (pseudoglioma) -0.00478106
CD1E CD1e molecule -0.00477431
MYO6 myosin VI -0.00477092
DEFA4 defensin, alpha 4, corticostatin -0.00475942
ALG6 ALG6, alpha-1,3-glucosyltransferase -0.00475539
RAB25 RAB25, member RAS oncogene family -0.004752
DUSP2 dual specificity phosphatase 2 -0.00473709
FBXO3 F-box protein 3 -0.004695
SIX2 SIX homeobox 2 -0.00469153
RESF1 retroelement silencing factor 1 -0.00468224
PRR16 proline rich 16 -0.00467925
PTK2B protein tyrosine kinase 2 beta -0.00466558
CDK14 cyclin-dependent kinase 14 -0.00466351
DGS2 DiGeorge syndrome/velocardiofacial syndrome complex 2 -0.00463891
DGKZ diacylglycerol kinase, zeta -0.00463542
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00462884
TMEM45A transmembrane protein 45A -0.00462552
XCL1 chemokine (C motif) ligand 1 -0.00459532
ACSL3 acyl-CoA synthetase long-chain family member 3 -0.0045944
VEGFA vascular endothelial growth factor A -0.00456888
NUP160 nucleoporin 160kDa -0.00456631
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.00455781
MGAM maltase-glucoamylase -0.00455747
FABP6 fatty acid binding protein 6, ileal -0.00455734
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -0.00455588
KRT23 keratin 23, type I -0.00455317
PKP1 plakophilin 1 -0.00455273
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -0.00454638
LCN2 lipocalin 2 -0.00453233
LRRC8B leucine rich repeat containing 8 family, member B -0.00450774
IRX5 iroquois homeobox 5 -0.00450635
GJA1 gap junction protein, alpha 1, 43kDa -0.00450575
COMP cartilage oligomeric matrix protein -0.00449915
NOTCH3 notch 3 -0.00449593
SMG7 SMG7 nonsense mediated mRNA decay factor -0.00449566
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) -0.00446377
TES testin LIM domain protein -0.00446156
PHACTR1 phosphatase and actin regulator 1 -0.00445843
KCTD12 potassium channel tetramerization domain containing 12 -0.00444953
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) -0.00442821
MEIS2 Meis homeobox 2 -0.00442435
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -0.00442316
PCTP phosphatidylcholine transfer protein -0.00441984
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.00440113
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -0.00439096
KIF20A kinesin family member 20A -0.00438969
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 -0.00437954
VPREB3 pre-B lymphocyte 3 -0.00437884
TIPRL TOR signaling pathway regulator -0.00437386
CDK8 cyclin-dependent kinase 8 -0.00436993
ACTL6A actin-like 6A -0.00434304
GABRP gamma-aminobutyric acid (GABA) A receptor, pi -0.00432929
CD2 CD2 molecule -0.00432128
VASP vasodilator-stimulated phosphoprotein -0.0043166
PNKP polynucleotide kinase 3'-phosphatase -0.00431254
SFTPB surfactant protein B -0.00431141
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -0.00429745
IKZF1 IKAROS family zinc finger 1 (Ikaros) -0.00429506
MPC2 mitochondrial pyruvate carrier 2 -0.00428964
MCTP1 multiple C2 domains, transmembrane 1 -0.00428669
MALL mal, T-cell differentiation protein-like -0.00427844
CAMP cathelicidin antimicrobial peptide -0.00427329
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00427163
WDR41 WD repeat domain 41 -0.0042621
LRRC59 leucine rich repeat containing 59 -0.00425809
TPST2 tyrosylprotein sulfotransferase 2 -0.00425515
KDM3B lysine (K)-specific demethylase 3B -0.00425227
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -0.00423929