REST Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description RE1-silencing transcription factor|This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described [provided by RefSeq, Jul 2010] (NCBI Entrez Gene Database, 5978)
Similar Terms
Downloads & Tools

Genes

135 target genes of the REST transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
ACTA1 actin, alpha 1, skeletal muscle
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional)
ANKRD34C ankyrin repeat domain 34C
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
BARHL1 BarH-like homeobox 1
BEX1 brain expressed, X-linked 1
BEX2 brain expressed X-linked 2
BEX4 brain expressed, X-linked 4
C3ORF14 chromosome 3 open reading frame 14
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CARTPT CART prepropeptide
CCDC33 coiled-coil domain containing 33
CDH23 cadherin-related 23
CELF4 CUGBP, Elav-like family member 4
CHAT choline O-acetyltransferase
CHGA chromogranin A
CHGB chromogranin B
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNTNAP2 contactin associated protein-like 2
CPNE9 copine family member IX
CRH corticotropin releasing hormone
CRYBA2 crystallin, beta A2
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTXN2 cortexin 2
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25
DLG4 discs, large homolog 4 (Drosophila)
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DPH2 DPH2 homolog (S. cerevisiae)
DPYSL2 dihydropyrimidinase-like 2
DVL1 dishevelled segment polarity protein 1
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC3L1 exocyst complex component 3-like 1
FAM78B family with sequence similarity 78, member B
FBLL1 fibrillarin-like 1
FGD2 FYVE, RhoGEF and PH domain containing 2
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAS2L2 growth arrest-specific 2 like 2
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1
GOLGA7B golgin A7 family, member B
GPR6 G protein-coupled receptor 6
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRM1 glutamate receptor, metabotropic 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3
HNF1A HNF1 homeobox A
HOOK1 hook microtubule-tethering protein 1
HOXD11 homeobox D11
HOXD3 homeobox D3
HPCA hippocalcin
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
INA internexin neuronal intermediate filament protein, alpha
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8
KCNQ1DN KCNQ1 downstream neighbor (non-protein coding)
KRT14 keratin 14, type I
KRT86 keratin 86, type II
LEP leptin
LOC200726 hCG1657980
LOC440040 glutamate receptor, metabotropic 5 pseudogene
MEIS3 Meis homeobox 3
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
MIR124-2 microRNA 124-2
MIR124-3 microRNA 124-3
MIR1253 microRNA 1253
MIR212 microRNA 212
MIR4475 microRNA 4475
MIR5580 microRNA 5580
MPV17 MpV17 mitochondrial inner membrane protein
NABP2 nucleic acid binding protein 2
NEFH neurofilament, heavy polypeptide
NEFM neurofilament, medium polypeptide
NEURL4 neuralized E3 ubiquitin protein ligase 4
NMS neuromedin S
NPAS4 neuronal PAS domain protein 4
NPPC natriuretic peptide C
NRSN1 neurensin 1
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
OTOA otoancorin
PAPD5 PAP associated domain containing 5
PAQR4 progestin and adipoQ receptor family member IV
PARD6A par-6 family cell polarity regulator alpha
PAXBP1-AS1 PAXBP1 antisense RNA 1
PCSK2 proprotein convertase subtilisin/kexin type 2
PENK proenkephalin
PKP4 plakophilin 4
POU4F2 POU class 4 homeobox 2
POU4F3 POU class 4 homeobox 3
PRMT8 protein arginine methyltransferase 8
PRNT prion protein (testis specific)
PTCHD2 patched domain containing 2
RGS7BP regulator of G-protein signaling 7 binding protein
RHCG Rh family, C glycoprotein
RNF13 ring finger protein 13
RPH3A rabphilin 3A
RXFP3 relaxin/insulin-like family peptide receptor 3
RXRB retinoid X receptor, beta
SARM1 sterile alpha and TIR motif containing 1
SCAMP5 secretory carrier membrane protein 5
SCN2A sodium channel, voltage gated, type II alpha subunit
SEC14L5 SEC14-like 5 (S. cerevisiae)
SFXN3 sideroflexin 3
SIRT6 sirtuin 6
SKAP1 src kinase associated phosphoprotein 1
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1
SLC35G2 solute carrier family 35, member G2
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SNAP25 synaptosomal-associated protein, 25kDa
SPTBN4 spectrin, beta, non-erythrocytic 4
SRM spermidine synthase
SST somatostatin
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
STMN2 stathmin 2
STMN4 stathmin-like 4
SYT14 synaptotagmin XIV
TCEAL6 transcription elongation factor A (SII)-like 6
TMCO4 transmembrane and coiled-coil domains 4
TMEM178B transmembrane protein 178B
TMEM181 transmembrane protein 181
TRMT61A tRNA methyltransferase 61A
TUBB3 tubulin, beta 3 class III
VRK3 vaccinia related kinase 3
VSTM2A V-set and transmembrane domain containing 2A
VSTM2L V-set and transmembrane domain containing 2 like
VWC2L von Willebrand factor C domain containing protein 2-like
XPR1 xenotropic and polytropic retrovirus receptor 1
ZNF638 zinc finger protein 638
ZNF653 zinc finger protein 653