REST Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description RE1-silencing transcription factor|This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described [provided by RefSeq, Jul 2010] (NCBI Entrez Gene Database, 5978)
External Link http://www.ncbi.nlm.nih.gov/gene/5978
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Genes

72 interacting proteins for REST from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CBX3 chromobox homolog 3
CDYL chromodomain protein, Y-like
CSNK1E casein kinase 1, epsilon
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CUL1 cullin 1
E2F6 E2F transcription factor 6
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EIF4A3 eukaryotic translation initiation factor 4A3
FBXW11 F-box and WD repeat domain containing 11
FBXW2 F-box and WD repeat domain containing 2
FBXW4 F-box and WD repeat domain containing 4
FBXW5 F-box and WD repeat domain containing 5
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FBXW8 F-box and WD repeat domain containing 8
GRIA2 glutamate receptor, ionotropic, AMPA 2
GTF2B general transcription factor IIB
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HIST1H2AA histone cluster 1, H2aa
HIST1H2AB histone cluster 1, H2ab
HIST1H2AC histone cluster 1, H2ac
HIST1H2AD histone cluster 1, H2ad
HIST1H2AH histone cluster 1, H2ah
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BA histone cluster 1, H2ba
HIST1H2BB histone cluster 1, H2bb
HIST1H2BD histone cluster 1, H2bd
HIST1H2BF histone cluster 1, H2bf
HIST1H2BH histone cluster 1, H2bh
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BK histone cluster 1, H2bk
HIST1H2BL histone cluster 1, H2bl
HIST1H2BM histone cluster 1, H2bm
HIST1H2BN histone cluster 1, H2bn
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HIST1H4F histone cluster 1, H4f
HIST2H2AA4 histone cluster 2, H2aa4
HIST2H2AB histone cluster 2, H2ab
HIST2H2AC histone cluster 2, H2ac
HIST2H2BE histone cluster 2, H2be
HIST2H2BF histone cluster 2, H2bf
HIST2H3A histone cluster 2, H3a
HIST3H2A histone cluster 3, H2a
HIST3H2BB histone cluster 3, H2bb
HTT huntingtin
KDM5C lysine (K)-specific demethylase 5C
L3MBTL1 l(3)mbt-like 1 (Drosophila)
MAX MYC associated factor X
MGA MGA, MAX dimerization protein
MMP16 matrix metallopeptidase 16 (membrane-inserted)
NCOR1 nuclear receptor corepressor 1
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
RCOR1 REST corepressor 1
RING1 ring finger protein 1
RNF2 ring finger protein 2
RPS27A ribosomal protein S27a
SIN3A SIN3 transcription regulator family member A
SIN3B SIN3 transcription regulator family member B
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
SP1 Sp1 transcription factor
SUB1 SUB1 homolog (S. cerevisiae)
TBP TATA box binding protein
TERF2 telomeric repeat binding factor 2
TFDP1 transcription factor Dp-1
UBC ubiquitin C