RET signaling Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-8853659
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Genes

41 proteins participating in the RET signaling pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ARTN artemin
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK2 docking protein 2, 56kDa
DOK4 docking protein 4
DOK5 docking protein 5
DOK6 docking protein 6
FRS2 fibroblast growth factor receptor substrate 2
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GDNF glial cell derived neurotrophic factor
GFRA1 GDNF family receptor alpha 1
GFRA2 GDNF family receptor alpha 2
GFRA3 GDNF family receptor alpha 3
GFRA4 GDNF family receptor alpha 4
GRB10 growth factor receptor-bound protein 10
GRB2 growth factor receptor-bound protein 2
GRB7 growth factor receptor-bound protein 7
IRS2 insulin receptor substrate 2
MAPK7 mitogen-activated protein kinase 7
NRTN neurturin
PDLIM7 PDZ and LIM domain 7 (enigma)
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PLCG1 phospholipase C, gamma 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKCA protein kinase C, alpha
PSPN persephin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAP1GAP RAP1 GTPase activating protein
RET ret proto-oncogene
SHANK3 SH3 and multiple ankyrin repeat domains 3
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SOS1 son of sevenless homolog 1 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase