RET Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description ret proto-oncogene|This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5979)
External Link https://ncbi.nlm.nih.gov/gene/5979
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Genes

499 genes differentially expressed following the RET gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CSTA cystatin A (stefin A) 0.0136226
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.0135758
RNF167 ring finger protein 167 0.0129368
ADIRF adipogenesis regulatory factor 0.0127298
AQP3 aquaporin 3 (Gill blood group) 0.0121538
S100A9 S100 calcium binding protein A9 0.0120615
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.0116955
SFN stratifin 0.0115956
S100A7 S100 calcium binding protein A7 0.0113844
JPT1 Jupiter microtubule associated homolog 1 0.0106555
IFI27 interferon, alpha-inducible protein 27 0.0105772
DEFB1 defensin, beta 1 0.0105655
CXCL14 chemokine (C-X-C motif) ligand 14 0.010536
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0105184
JCHAIN joining chain of multimeric IgA and IgM 0.0104614
POU2AF1 POU class 2 associating factor 1 0.0101163
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00988671
MGP matrix Gla protein 0.00953313
NVL nuclear VCP-like 0.00936609
DAXX death-domain associated protein 0.00896011
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.00888404
IFITM1 interferon induced transmembrane protein 1 0.00880719
SLPI secretory leukocyte peptidase inhibitor 0.00868099
IGFBP5 insulin-like growth factor binding protein 5 0.00857401
LAMP3 lysosomal-associated membrane protein 3 0.00847328
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00846395
FKBP11 FK506 binding protein 11, 19 kDa 0.00839175
TUBB2A tubulin, beta 2A class IIa 0.00838195
DEGS1 delta(4)-desaturase, sphingolipid 1 0.00821099
PDZK1IP1 PDZK1 interacting protein 1 0.00814195
MMP12 matrix metallopeptidase 12 0.00802539
APOD apolipoprotein D 0.00801272
GPM6B glycoprotein M6B 0.00798992
PLIN2 perilipin 2 0.00797495
BIRC3 baculoviral IAP repeat containing 3 0.00792634
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.00786978
CXCL13 chemokine (C-X-C motif) ligand 13 0.00786941
PPP1R16B protein phosphatase 1, regulatory subunit 16B 0.0078614
PI3 peptidase inhibitor 3, skin-derived 0.0078455
SPRR1B small proline-rich protein 1B 0.00776471
FXYD2 FXYD domain containing ion transport regulator 2 0.00771301
EAF2 ELL associated factor 2 0.0076323
HIST1H2AC histone cluster 1, H2ac 0.00761364
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00760939
MZB1 marginal zone B and B1 cell-specific protein 0.00759258
MALL mal, T-cell differentiation protein-like 0.00755192
CYTIP cytohesin 1 interacting protein 0.00746329
BAMBI BMP and activin membrane-bound inhibitor 0.00736456
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00729328
S100A2 S100 calcium binding protein A2 0.00721363
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00721112
SPRR2B small proline-rich protein 2B 0.00720692
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5 0.0071517
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00715115
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.0071193
ERGIC2 ERGIC and golgi 2 0.00707093
KRT1 keratin 1, type II 0.00706776
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00706687
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00701139
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00695986
XPO7 exportin 7 0.00693418
TAC1 tachykinin, precursor 1 0.00693253
OLFM4 olfactomedin 4 0.00691633
AMDHD2 amidohydrolase domain containing 2 0.00689081
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.00683895
HSPA8 heat shock 70kDa protein 8 0.00679679
CD8A CD8a molecule 0.00674896
TFPI2 tissue factor pathway inhibitor 2 0.00673468
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.00672904
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00672886
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.00668058
AQP1 aquaporin 1 (Colton blood group) 0.00667752
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.00666793
SNX10 sorting nexin 10 0.0065681
PTGES prostaglandin E synthase 0.00651672
COCH cochlin 0.00651085
MX1 MX dynamin-like GTPase 1 0.00649522
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00647722
PLAU plasminogen activator, urokinase 0.00646767
HNMT histamine N-methyltransferase 0.00645651
SEC62 SEC62 homolog (S. cerevisiae) 0.00642607
CD93 CD93 molecule 0.00640866
ACP5 acid phosphatase 5, tartrate resistant 0.00640664
LY6D lymphocyte antigen 6 complex, locus D 0.00640033
KRT5 keratin 5, type II 0.00639505
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 0.00638201
RAB9A RAB9A, member RAS oncogene family 0.00637557
STOM stomatin 0.0063532
HSPH1 heat shock 105kDa/110kDa protein 1 0.00634494
ATP5PD ATP synthase peripheral stalk subunit d 0.00632056
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.0063004
KRT6A keratin 6A, type II 0.00629629
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.00629583
ARMCX3 armadillo repeat containing, X-linked 3 0.00626871
CCL5 chemokine (C-C motif) ligand 5 0.00625291
SMAD6 SMAD family member 6 0.00624967
CCL13 chemokine (C-C motif) ligand 13 0.00619883
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.00619855
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00618853
NEFM neurofilament, medium polypeptide 0.00617463
CD79A CD79a molecule, immunoglobulin-associated alpha 0.00617159
C6ORF48 chromosome 6 open reading frame 48 0.00616512
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.00609932
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.00607884
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.00607149
ARID5B AT rich interactive domain 5B (MRF1-like) 0.00605304
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.00602637
NUP85 nucleoporin 85kDa 0.00602054
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.0060015
DPEP1 dipeptidase 1 (renal) 0.00599681
RNASE6 ribonuclease, RNase A family, k6 0.00597711
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.00595325
ESD esterase D 0.00595321
KRT6B keratin 6B, type II 0.00595244
MMP1 matrix metallopeptidase 1 0.00593428
TGM2 transglutaminase 2 0.0059271
TACSTD2 tumor-associated calcium signal transducer 2 0.00592698
METTL7A methyltransferase like 7A 0.00592153
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.00590766
C1ORF54 chromosome 1 open reading frame 54 0.00590629
CTSH cathepsin H 0.00588655
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.0058798
GEM GTP binding protein overexpressed in skeletal muscle 0.00587893
IL2RG interleukin 2 receptor, gamma 0.00586787
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.00586434
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00585122
GNG5 guanine nucleotide binding protein (G protein), gamma 5 0.00583914
PEBP1 phosphatidylethanolamine binding protein 1 0.00582727
ALOX5 arachidonate 5-lipoxygenase 0.00581816
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00580931
LPAR6 lysophosphatidic acid receptor 6 0.00579385
FOXO1 forkhead box O1 0.00578912
LTF lactotransferrin 0.00578235
RPS26 ribosomal protein S26 0.00574461
PENK proenkephalin 0.00572967
PLBD1 phospholipase B domain containing 1 0.0057294
KRT17 keratin 17, type I 0.00572871
SH3GLB1 SH3-domain GRB2-like endophilin B1 0.00572072
SLAMF7 SLAM family member 7 0.00571995
CHRDL1 chordin-like 1 0.00571881
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.00570154
TOR3A torsin family 3, member A 0.00570066
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00567403
RCAN1 regulator of calcineurin 1 0.00566501
CAPN3 calpain 3, (p94) 0.00566036
TSPAN7 tetraspanin 7 0.00563484
TSPAN8 tetraspanin 8 0.00562969
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00562528
DMBT1 deleted in malignant brain tumors 1 0.00561531
ISCU iron-sulfur cluster assembly enzyme 0.00559857
SPRR1A small proline-rich protein 1A 0.00558482
CNIH4 cornichon family AMPA receptor auxiliary protein 4 0.00556565
MMD monocyte to macrophage differentiation-associated 0.00556537
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 0.00556459
SNAP25 synaptosomal-associated protein, 25kDa 0.00552898
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 0.00552361
OSBPL8 oxysterol binding protein-like 8 0.00550367
UBE2J1 ubiquitin-conjugating enzyme E2, J1 0.0054917
CD27 CD27 molecule 0.00548559
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.00547872
CHP1 calcineurin-like EF-hand protein 1 0.00547732
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.00546829
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00546814
HLA-DOB major histocompatibility complex, class II, DO beta 0.00542875
CST7 cystatin F (leukocystatin) 0.00542531
MICB MHC class I polypeptide-related sequence B 0.00542334
HCK HCK proto-oncogene, Src family tyrosine kinase 0.00542312
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.005422
KRT14 keratin 14, type I 0.00538864
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.00538818
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00538416
SYT1 synaptotagmin I 0.00537316
TFRC transferrin receptor 0.00537314
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00536418
RGS4 regulator of G-protein signaling 4 0.00535609
CLMN calmin (calponin-like, transmembrane) 0.00535336
RHCG Rh family, C glycoprotein 0.00534617
GPR137B G protein-coupled receptor 137B 0.00533031
GNG7 guanine nucleotide binding protein (G protein), gamma 7 0.00532597
PPARG peroxisome proliferator-activated receptor gamma 0.0053121
GPX7 glutathione peroxidase 7 0.00530831
GPR65 G protein-coupled receptor 65 0.00529559
MXRA7 matrix-remodelling associated 7 0.00525525
SPOP speckle-type POZ protein 0.00524048
MCAM melanoma cell adhesion molecule 0.0052355
AMZ2 archaelysin family metallopeptidase 2 0.00523309
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00522552
ATG3 autophagy related 3 0.00521378
CST6 cystatin E/M 0.00521191
PALLD palladin, cytoskeletal associated protein 0.00518573
OASL 2'-5'-oligoadenylate synthetase-like 0.00517994
RPL14 ribosomal protein L14 0.00517123
CRYM crystallin, mu 0.00516876
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.00515007
SMYD2 SET and MYND domain containing 2 0.00514622
MSMO1 methylsterol monooxygenase 1 0.00512957
RAB33A RAB33A, member RAS oncogene family 0.00512403
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 0.00512365
PNRC1 proline-rich nuclear receptor coactivator 1 0.00512072
EDNRB endothelin receptor type B 0.00512
CCL4 chemokine (C-C motif) ligand 4 0.0051179
GZMK granzyme K (granzyme 3; tryptase II) 0.00511224
GYG1 glycogenin 1 0.00510173
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.00509706
BPGM 2,3-bisphosphoglycerate mutase 0.00508263
ZNF277 zinc finger protein 277 0.0050802
KLK6 kallikrein-related peptidase 6 0.00507909
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.0050718
PLAAT3 phospholipase A and acyltransferase 3 0.0050581
EIF3E eukaryotic translation initiation factor 3, subunit E 0.00505222
CCL17 chemokine (C-C motif) ligand 17 0.00504749
CHN2 chimerin 2 0.00502937
PLCL1 phospholipase C-like 1 0.00500881
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00500737
BAG2 BCL2-associated athanogene 2 0.00499529
LAX1 lymphocyte transmembrane adaptor 1 0.004995
DCK deoxycytidine kinase 0.00498946
EPS8 epidermal growth factor receptor pathway substrate 8 0.0049834
SRGN serglycin 0.00497141
LEPROT leptin receptor overlapping transcript 0.00496996
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00495345
ARHGAP6 Rho GTPase activating protein 6 0.00495245
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.00495209
SH3YL1 SH3 and SYLF domain containing 1 0.00494321
TMEM243 transmembrane protein 243, mitochondrial 0.00493233
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.00493057
SP110 SP110 nuclear body protein 0.00492764
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 0.00492517
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 0.00492033
ADRA2A adrenoceptor alpha 2A 0.00491653
XCL1 chemokine (C motif) ligand 1 0.00490701
PNOC prepronociceptin 0.00489514
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 0.00487446
MRPS33 mitochondrial ribosomal protein S33 0.00487202
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00487177
ALCAM activated leukocyte cell adhesion molecule 0.00486729
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.0048551
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.0048521
FRZB frizzled-related protein 0.00484695
IFI44L interferon-induced protein 44-like 0.00484191
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.00483223
IGBP1 immunoglobulin (CD79A) binding protein 1 0.00483211
TRIM8 tripartite motif containing 8 0.00483209
PUDP pseudouridine 5'-phosphatase 0.00483131
DUSP22 dual specificity phosphatase 22 0.0048293
RPL26L1 ribosomal protein L26-like 1 0.00482512
MAOA monoamine oxidase A 0.00482134
SFTPC surfactant protein C 0.00480845
IRF7 interferon regulatory factor 7 0.0048077
ASS1 argininosuccinate synthase 1 0.00479819

decreased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 -0.0204464
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.0129188
EFNB2 ephrin-B2 -0.0107667
CPB1 carboxypeptidase B1 (tissue) -0.0101969
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00993455
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0094386
FBN2 fibrillin 2 -0.00941104
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00888026
MFAP2 microfibrillar-associated protein 2 -0.00883998
KANK1 KN motif and ankyrin repeat domains 1 -0.00879681
NOTCH2 notch 2 -0.00865133
BTBD3 BTB (POZ) domain containing 3 -0.00832264
TFF3 trefoil factor 3 (intestinal) -0.00830938
PHACTR2 phosphatase and actin regulator 2 -0.00826204
CLU clusterin -0.00797709
ADGRE1 adhesion G protein-coupled receptor E1 -0.00796234
SCGB2A1 secretoglobin, family 2A, member 1 -0.00795035
GPX3 glutathione peroxidase 3 -0.0076914
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B -0.00768716
KDM5D lysine (K)-specific demethylase 5D -0.00767054
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00766602
VNN1 vanin 1 -0.0075833
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00756418
CST3 cystatin C -0.00739668
DACH1 dachshund family transcription factor 1 -0.00722259
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.00720132
APOB apolipoprotein B -0.00713826
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 -0.00711505
RHOBTB3 Rho-related BTB domain containing 3 -0.00707429
BMP2 bone morphogenetic protein 2 -0.00704692
STK10 serine/threonine kinase 10 -0.0070285
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.0070102
AMH anti-Mullerian hormone -0.00697242
SNX7 sorting nexin 7 -0.00692625
MB myoglobin -0.00689206
MEIS1 Meis homeobox 1 -0.0068195
APOA2 apolipoprotein A-II -0.00680779
CSK c-src tyrosine kinase -0.00677271
MMP2 matrix metallopeptidase 2 -0.00667651
TMEM158 transmembrane protein 158 (gene/pseudogene) -0.00666285
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -0.00663071
HOMER3 homer scaffolding protein 3 -0.0066142
PSRC1 proline/serine-rich coiled-coil 1 -0.00660789
FBN1 fibrillin 1 -0.00658558
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.00656294
CRP C-reactive protein, pentraxin-related -0.00654601
MTCL1 microtubule crosslinking factor 1 -0.00652337
EXT1 exostosin glycosyltransferase 1 -0.0064943
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00648775
AHSG alpha-2-HS-glycoprotein -0.00647661
GOLGA8A golgin A8 family, member A -0.00642728
SPEN spen family transcriptional repressor -0.00640863
CGA glycoprotein hormones, alpha polypeptide -0.0063707
ABLIM1 actin binding LIM protein 1 -0.00633918
TCEA2 transcription elongation factor A (SII), 2 -0.00631412
AURKB aurora kinase B -0.00630583
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00625708
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.00625441
PFKL phosphofructokinase, liver -0.00618988
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00617349
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -0.00617144
KIF1B kinesin family member 1B -0.00616974
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00615624
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00612206
UBE2M ubiquitin-conjugating enzyme E2M -0.0060948
TSEN34 TSEN34 tRNA splicing endonuclease subunit -0.00607527
ELN elastin -0.00606177
RRBP1 ribosome binding protein 1 -0.00600615
NRCAM neuronal cell adhesion molecule -0.00599843
ANKRD10 ankyrin repeat domain 10 -0.00599172
SLIT2 slit homolog 2 (Drosophila) -0.00596412
COL4A5 collagen, type IV, alpha 5 -0.00595782
MTA1 metastasis associated 1 -0.0059483
GSTA1 glutathione S-transferase alpha 1 -0.00594323
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00594274
MYO6 myosin VI -0.00594039
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0059384
NOVA1 neuro-oncological ventral antigen 1 -0.00592696
FBXL7 F-box and leucine-rich repeat protein 7 -0.00592557
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 -0.00592275
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00591385
MFAP5 microfibrillar associated protein 5 -0.00591023
HYOU1 hypoxia up-regulated 1 -0.00586266
OBSL1 obscurin-like 1 -0.00586158
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.00585135
DOCK9 dedicator of cytokinesis 9 -0.00583994
NNMT nicotinamide N-methyltransferase -0.00583371
ERBB4 erb-b2 receptor tyrosine kinase 4 -0.00580264
ESR1 estrogen receptor 1 -0.00577292
TSPO translocator protein (18kDa) -0.0057706
TFF1 trefoil factor 1 -0.00572443
ACADVL acyl-CoA dehydrogenase, very long chain -0.00572385
UBE2S ubiquitin-conjugating enzyme E2S -0.00572087
IRX5 iroquois homeobox 5 -0.00571713
PXDN peroxidasin -0.00571035
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00569129
COL1A2 collagen, type I, alpha 2 -0.00569089
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00567533
IRS2 insulin receptor substrate 2 -0.00567239
TFF2 trefoil factor 2 -0.00565185
PLPP2 phospholipid phosphatase 2 -0.00565092
POSTN periostin, osteoblast specific factor -0.00564692
PODXL podocalyxin-like -0.00561596
MGLL monoglyceride lipase -0.00559144
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -0.0055819
TXLNA taxilin alpha -0.0055743
CA3 carbonic anhydrase III -0.0055513
CTSZ cathepsin Z -0.0055321
FRY furry homolog (Drosophila) -0.00552048
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.00550354
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.00548965
DMPK dystrophia myotonica-protein kinase -0.00547752
NIT1 nitrilase 1 -0.00546117
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00546086
RAD21 RAD21 homolog (S. pombe) -0.00545187
FHL1 four and a half LIM domains 1 -0.00542509
ATG4B autophagy related 4B, cysteine peptidase -0.00542159
CD9 CD9 molecule -0.00542095
ACTC1 actin, alpha, cardiac muscle 1 -0.00539635
CDK11A cyclin-dependent kinase 11A -0.00537686
RRAGA Ras-related GTP binding A -0.00537232
NUCB1 nucleobindin 1 -0.0053632
TUBB4B tubulin, beta 4B class IVb -0.0053501
TNNT1 troponin T type 1 (skeletal, slow) -0.00533745
TARDBP TAR DNA binding protein -0.00533154
DSP desmoplakin -0.00532795
FST follistatin -0.00531958
SGK1 serum/glucocorticoid regulated kinase 1 -0.00531201
CSF1 colony stimulating factor 1 (macrophage) -0.00530453
FOXE1 forkhead box E1 -0.00530249
NAV2 neuron navigator 2 -0.00529283
LMNB2 lamin B2 -0.00529175
EML3 echinoderm microtubule associated protein like 3 -0.00528167
TUFT1 tuftelin 1 -0.00523757
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 -0.00522821
TSPAN5 tetraspanin 5 -0.00522424
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.00522098
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00521571
BEX4 brain expressed, X-linked 4 -0.00521443
APMAP adipocyte plasma membrane associated protein -0.00519276
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -0.00518371
NOTCH2NL notch 2 N-terminal like -0.00515262
ATP13A2 ATPase type 13A2 -0.00515117
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.00514903
KRAS Kirsten rat sarcoma viral oncogene homolog -0.0051448
AK1 adenylate kinase 1 -0.00512681
TLE4 transducin-like enhancer of split 4 -0.00512454
PSG5 pregnancy specific beta-1-glycoprotein 5 -0.0051137
ADAM28 ADAM metallopeptidase domain 28 -0.00511188
TNS3 tensin 3 -0.00509337
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.00506361
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -0.00505977
MYH2 myosin, heavy chain 2, skeletal muscle, adult -0.00505221
SOX17 SRY (sex determining region Y)-box 17 -0.00505133
SSBP2 single-stranded DNA binding protein 2 -0.00503646
TRIB1 tribbles pseudokinase 1 -0.00503592
ADI1 acireductone dioxygenase 1 -0.00502962
SOX11 SRY (sex determining region Y)-box 11 -0.00500274
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.00497273
JAG1 jagged 1 -0.00496721
GBP1 guanylate binding protein 1, interferon-inducible -0.00496659
DLK1 delta-like 1 homolog (Drosophila) -0.00495571
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.00493758
MCF2L MCF.2 cell line derived transforming sequence-like -0.0049312
MRPS30 mitochondrial ribosomal protein S30 -0.0049242
VTCN1 V-set domain containing T cell activation inhibitor 1 -0.00491098
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A -0.00490748
POR P450 (cytochrome) oxidoreductase -0.00490051
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 -0.00489383
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00488577
STX1A syntaxin 1A (brain) -0.00488322
TNNC1 troponin C type 1 (slow) -0.00487098
KRT18 keratin 18, type I -0.00486233
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 -0.00486218
ANXA10 annexin A10 -0.00486039
TWIST1 twist family bHLH transcription factor 1 -0.00484657
TGFB1 transforming growth factor, beta 1 -0.0048416
CPD carboxypeptidase D -0.00483991
TMEM14A transmembrane protein 14A -0.00483848
EFHD2 EF-hand domain family, member D2 -0.0048362
DGKZ diacylglycerol kinase, zeta -0.00483572
HIP1 huntingtin interacting protein 1 -0.00482174
ACO1 aconitase 1, soluble -0.00481177
TAGLN2 transgelin 2 -0.00480938
MAGED1 melanoma antigen family D1 -0.00478624
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00478273
CYFIP1 cytoplasmic FMR1 interacting protein 1 -0.00478105
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) -0.00477778
NFASC neurofascin -0.00476233
PMM2 phosphomannomutase 2 -0.00475457
EMX2 empty spiracles homeobox 2 -0.00474718
LRRC15 leucine rich repeat containing 15 -0.00473912
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -0.00473472
PAX6 paired box 6 -0.00473053
BCAP31 B-cell receptor-associated protein 31 -0.00472002
MAGEA3 melanoma antigen family A3 -0.00471779
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -0.00470208
MAPKBP1 mitogen-activated protein kinase binding protein 1 -0.00470081
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 -0.00470004
DVL1 dishevelled segment polarity protein 1 -0.00469279
MYL2 myosin, light chain 2, regulatory, cardiac, slow -0.00468685
CUL4A cullin 4A -0.00468547
CREB1 cAMP responsive element binding protein 1 -0.00467955
EMP3 epithelial membrane protein 3 -0.00466468
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00464732
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.0046456
RUVBL2 RuvB-like AAA ATPase 2 -0.00464405
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 -0.0046311
APOC3 apolipoprotein C-III -0.00462525
H2AX H2A.X variant histone -0.00461975
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00460813
MYO7A myosin VIIA -0.00459031
PPIE peptidylprolyl isomerase E (cyclophilin E) -0.00456603
SDF4 stromal cell derived factor 4 -0.00454957
INPPL1 inositol polyphosphate phosphatase-like 1 -0.00454219
HLA-G major histocompatibility complex, class I, G -0.00452779
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.00451886
NRTN neurturin -0.00451692
HHEX hematopoietically expressed homeobox -0.0045049
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.00450174
PNKP polynucleotide kinase 3'-phosphatase -0.00450144
IFT81 intraflagellar transport 81 -0.00447783
NPTX2 neuronal pentraxin II -0.00446199
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00446158
F3 coagulation factor III (thromboplastin, tissue factor) -0.00446036
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 -0.00445449
CBS cystathionine-beta-synthase -0.00445203
BSG basigin (Ok blood group) -0.0044503
C1QA complement component 1, q subcomponent, A chain -0.00444512
PRKCSH protein kinase C substrate 80K-H -0.00442797
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -0.00442503
MAEA macrophage erythroblast attacher -0.00442397
BEX1 brain expressed, X-linked 1 -0.00442113
HOOK2 hook microtubule-tethering protein 2 -0.00441794
PDGFRL platelet-derived growth factor receptor-like -0.00441105
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) -0.00441008
HOXB2 homeobox B2 -0.00440951
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00440016
CDC34 cell division cycle 34 -0.00439711
ZSCAN18 zinc finger and SCAN domain containing 18 -0.00438343
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -0.00437918
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00436499
SOD2 superoxide dismutase 2, mitochondrial -0.00436378
GOLGA2 golgin A2 -0.00435193
FAM114A1 family with sequence similarity 114, member A1 -0.00435105
FARSA phenylalanyl-tRNA synthetase, alpha subunit -0.00434693
NTS neurotensin -0.00433875
MN1 meningioma (disrupted in balanced translocation) 1 -0.00433611
IPO9 importin 9 -0.00433536