RFC4 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description replication factor C (activator 1) 4, 37kDa|The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5984)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RFC4
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Genes

193 co-expressed genes for RFC4 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ACTL6A actin-like 6A
AFG3L2 AFG3-like AAA ATPase 2
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ALG3 ALG3, alpha-1,3- mannosyltransferase
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
ATXN10 ataxin 10
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BIRC5 baculoviral IAP repeat containing 5
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CCNA2 cyclin A2
CCNB2 cyclin B2
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CDK1 cyclin-dependent kinase 1
CDK11A cyclin-dependent kinase 11A
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CENPF centromere protein F, 350/400kDa
CHAF1A chromatin assembly factor 1, subunit A (p150)
CKS1B CDC28 protein kinase regulatory subunit 1B
CKS2 CDC28 protein kinase regulatory subunit 2
CS citrate synthase
CTPS1 CTP synthase 1
CYCS cytochrome c, somatic
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DEK DEK proto-oncogene
DGUOK deoxyguanosine kinase
DKC1 dyskeratosis congenita 1, dyskerin
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DOCK3 dedicator of cytokinesis 3
DUT deoxyuridine triphosphatase
EI24 etoposide induced 2.4
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF3I eukaryotic translation initiation factor 3, subunit I
EPRS glutamyl-prolyl-tRNA synthetase
ESD esterase D
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
FANCI Fanconi anemia, complementation group I
FEN1 flap structure-specific endonuclease 1
FH fumarate hydratase
FOXM1 forkhead box M1
GARS glycyl-tRNA synthetase
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GMNN geminin, DNA replication inhibitor
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
GPN1 GPN-loop GTPase 1
GTF2A2 general transcription factor IIA, 2, 12kDa
H2AFZ H2A histone family, member Z
HADH hydroxyacyl-CoA dehydrogenase
HAT1 histone acetyltransferase 1
HCCS holocytochrome c synthase
HDAC2 histone deacetylase 2
HDDC2 HD domain containing 2
HMMR hyaluronan-mediated motility receptor (RHAMM)
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HSPE1 heat shock 10kDa protein 1
IARS isoleucyl-tRNA synthetase
ICE1 interactor of little elongation complex ELL subunit 1
IFRD1 interferon-related developmental regulator 1
ILF2 interleukin enhancer binding factor 2
IMMT inner membrane protein, mitochondrial
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KHSRP KH-type splicing regulatory protein
KIAA0101 KIAA0101
KIF11 kinesin family member 11
KIF14 kinesin family member 14
KNTC1 kinetochore associated 1
LIG1 ligase I, DNA, ATP-dependent
LRPPRC leucine-rich pentatricopeptide repeat containing
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPLA1 lysophospholipase I
MARS methionyl-tRNA synthetase
MCFD2 multiple coagulation factor deficiency 2
MCM10 minichromosome maintenance complex component 10
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM6 minichromosome maintenance complex component 6
MCM7 minichromosome maintenance complex component 7
METAP1 methionyl aminopeptidase 1
MLEC malectin
MLH1 mutL homolog 1
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MRPS18B mitochondrial ribosomal protein S18B
MRPS27 mitochondrial ribosomal protein S27
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTCP1 mature T-cell proliferation 1
MTX2 metaxin 2
NAE1 NEDD8 activating enzyme E1 subunit 1
NASP nuclear autoantigenic sperm protein (histone-binding)
NCAPD2 non-SMC condensin I complex, subunit D2
NCBP2 nuclear cap binding protein subunit 2, 20kDa
NDC80 NDC80 kinetochore complex component
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
NONO non-POU domain containing, octamer-binding
NUDC nudC nuclear distribution protein
NUP188 nucleoporin 188kDa
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PCNA proliferating cell nuclear antigen
PDHB pyruvate dehydrogenase (lipoamide) beta
PLK4 polo-like kinase 4
PMEL premelanosome protein
POM121 POM121 transmembrane nucleoporin
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPT1 palmitoyl-protein thioesterase 1
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTGES3 prostaglandin E synthase 3 (cytosolic)
R3HDM1 R3H domain containing 1
RAD23A RAD23 homolog A (S. cerevisiae)
RAD51AP1 RAD51 associated protein 1
RAD54L RAD54-like (S. cerevisiae)
RAN RAN, member RAS oncogene family
RANBP1 RAN binding protein 1
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RFC5 replication factor C (activator 1) 5, 36.5kDa
RPA1 replication protein A1, 70kDa
RPA3 replication protein A3, 14kDa
RRM1 ribonucleotide reductase M1
RUVBL2 RuvB-like AAA ATPase 2
SAFB scaffold attachment factor B
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SEC63 SEC63 homolog (S. cerevisiae)
SERP1 stress-associated endoplasmic reticulum protein 1
SET SET nuclear proto-oncogene
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SLBP stem-loop binding protein
SMC2 structural maintenance of chromosomes 2
SMC4 structural maintenance of chromosomes 4
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SNRPA small nuclear ribonucleoprotein polypeptide A
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SNRPE small nuclear ribonucleoprotein polypeptide E
SPAG5 sperm associated antigen 5
SRPK1 SRSF protein kinase 1
SRRM1 serine/arginine repetitive matrix 1
SRSF1 serine/arginine-rich splicing factor 1
SSB Sjogren syndrome antigen B (autoantigen La)
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SSRP1 structure specific recognition protein 1
STK24 serine/threonine kinase 24
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
TARS threonyl-tRNA synthetase
TCEA1 transcription elongation factor A (SII), 1
TFDP1 transcription factor Dp-1
TGDS TDP-glucose 4,6-dehydratase
TIMELESS timeless circadian clock
TNPO3 transportin 3
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOP2A topoisomerase (DNA) II alpha 170kDa
TREX2 three prime repair exonuclease 2
TRIP13 thyroid hormone receptor interactor 13
TRRAP transformation/transcription domain-associated protein
TTK TTK protein kinase
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
UBE2S ubiquitin-conjugating enzyme E2S
UNG uracil-DNA glycosylase
USP1 ubiquitin specific peptidase 1
VDAC1 voltage-dependent anion channel 1
VDAC2 voltage-dependent anion channel 2
VDAC3 voltage-dependent anion channel 3
WHSC1 Wolf-Hirschhorn syndrome candidate 1
XPO1 exportin 1
XPO7 exportin 7
XPOT exportin, tRNA
YARS tyrosyl-tRNA synthetase
ZNF131 zinc finger protein 131
ZPR1 ZPR1 zinc finger
ZWINT ZW10 interacting kinetochore protein