RFC5 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description replication factor C (activator 1) 5, 36.5kDa|The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9. [provided by RefSeq, May 2011] (NCBI Entrez Gene Database, 5985)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_RFC5
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Genes

76 co-expressed genes for RFC5 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AFF2 AF4/FMR2 family, member 2
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ARHGAP11A Rho GTPase activating protein 11A
ATRX alpha thalassemia/mental retardation syndrome X-linked
BRCA1 breast cancer 1, early onset
C1ORF216 chromosome 1 open reading frame 216
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNF cyclin F
CEP135 centrosomal protein 135kDa
CHD9 chromodomain helicase DNA binding protein 9
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CRHR1 corticotropin releasing hormone receptor 1
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DPT dermatopontin
EIF5B eukaryotic translation initiation factor 5B
EP400 E1A binding protein p400
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
FDXR ferredoxin reductase
FOSL1 FOS-like antigen 1
FRYL FRY-like
GLE1 GLE1 RNA export mediator
GPR15 G protein-coupled receptor 15
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIP2 glutamate receptor interacting protein 2
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HABP4 hyaluronan binding protein 4
IPCEF1 interaction protein for cytohesin exchange factors 1
JRK Jrk homolog (mouse)
KANK2 KN motif and ankyrin repeat domains 2
KAZN kazrin, periplakin interacting protein
KRT33A keratin 33A, type I
KRT86 keratin 86, type II
LPGAT1 lysophosphatidylglycerol acyltransferase 1
MLN motilin
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MPHOSPH6 M-phase phosphoprotein 6
MUTYH mutY homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCKIPSD NCK interacting protein with SH3 domain
NFRKB nuclear factor related to kappaB binding protein
NFX1 nuclear transcription factor, X-box binding 1
NKRF NFKB repressing factor
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PAX7 paired box 7
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PHF10 PHD finger protein 10
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
PPP5C protein phosphatase 5, catalytic subunit
RFC5 replication factor C (activator 1) 5, 36.5kDa
RUNX1 runt-related transcription factor 1
SCAMP1 secretory carrier membrane protein 1
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SYNJ2 synaptojanin 2
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPP2 tripeptidyl peptidase II
TRIM27 tripartite motif containing 27
TTI1 TELO2 interacting protein 1
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
UBE4B ubiquitination factor E4B
WDR62 WD repeat domain 62
ZBTB14 zinc finger and BTB domain containing 14
ZNF200 zinc finger protein 200
ZNF330 zinc finger protein 330