| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | regulatory factor X, 5 (influences HLA class II expression)|A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS; MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5993) |
| External Link | https://ncbi.nlm.nih.gov/gene/5993 |
| Similar Terms | |
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499 genes differentially expressed following the RFX5 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | 0.0105091 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00907224 |
| LBH | limb bud and heart development | 0.00865586 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00788871 |
| C6ORF48 | chromosome 6 open reading frame 48 | 0.00768877 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.00767787 |
| TRIM22 | tripartite motif containing 22 | 0.00764167 |
| OXTR | oxytocin receptor | 0.00759703 |
| MT1X | metallothionein 1X | 0.00751074 |
| RCAN1 | regulator of calcineurin 1 | 0.00749255 |
| GNAS | GNAS complex locus | 0.00745197 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00740653 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00730711 |
| ASS1 | argininosuccinate synthase 1 | 0.00726668 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.00714592 |
| RGS10 | regulator of G-protein signaling 10 | 0.00695008 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00694261 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.00691323 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00676513 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00674277 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.00666359 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00664107 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00659222 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00655747 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00652052 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00647342 |
| MVP | major vault protein | 0.00645718 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.00643656 |
| JUN | jun proto-oncogene | 0.00628621 |
| SMS | spermine synthase | 0.00620948 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00620187 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00618928 |
| ZNF274 | zinc finger protein 274 | 0.00617495 |
| RGS4 | regulator of G-protein signaling 4 | 0.00617126 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00616406 |
| CLDN8 | claudin 8 | 0.00613986 |
| COG7 | component of oligomeric golgi complex 7 | 0.00612392 |
| XPO7 | exportin 7 | 0.00608683 |
| MT1G | metallothionein 1G | 0.00608129 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.00606893 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.00606686 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00602278 |
| RRAGD | Ras-related GTP binding D | 0.00601028 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.00600774 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.00599499 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00598407 |
| RIOK3 | RIO kinase 3 | 0.00594085 |
| BPGM | 2,3-bisphosphoglycerate mutase | 0.00589834 |
| CDK14 | cyclin-dependent kinase 14 | 0.00588099 |
| MME | membrane metallo-endopeptidase | 0.00587642 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00586437 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00583945 |
| HMOX1 | heme oxygenase 1 | 0.00582408 |
| MT1HL1 | metallothionein 1H-like 1 | 0.0057617 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00575334 |
| PITX3 | paired-like homeodomain 3 | 0.00575208 |
| CAST | calpastatin | 0.00573921 |
| CLTB | clathrin, light chain B | 0.00573835 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.00573473 |
| ZNF91 | zinc finger protein 91 | 0.00570873 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.00566517 |
| ATF3 | activating transcription factor 3 | 0.00564056 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.00562694 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00556434 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.00556333 |
| PNMA8A | PNMA family member 8A | 0.00553063 |
| TMEM255A | transmembrane protein 255A | 0.00551378 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 0.00550929 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | 0.00548333 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00548316 |
| ANXA1 | annexin A1 | 0.00546469 |
| ACP5 | acid phosphatase 5, tartrate resistant | 0.0054592 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 0.00538267 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00537302 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 0.00535625 |
| PSAP | prosaposin | 0.00533913 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00533179 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0053285 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | 0.00531453 |
| GPM6B | glycoprotein M6B | 0.00529943 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00523047 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | 0.00521339 |
| RPL36 | ribosomal protein L36 | 0.00517572 |
| SLC25A38 | solute carrier family 25, member 38 | 0.00517434 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 | 0.00516061 |
| SP100 | SP100 nuclear antigen | 0.00515062 |
| MT1H | metallothionein 1H | 0.00513949 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.00513742 |
| CCND3 | cyclin D3 | 0.00511094 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00509157 |
| NCALD | neurocalcin delta | 0.00508607 |
| ABHD2 | abhydrolase domain containing 2 | 0.00505784 |
| RNASET2 | ribonuclease T2 | 0.00500088 |
| TRIM8 | tripartite motif containing 8 | 0.00500054 |
| ELOVL1 | ELOVL fatty acid elongase 1 | 0.00499106 |
| UFM1 | ubiquitin-fold modifier 1 | 0.004943 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0049084 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.00490552 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | 0.00489174 |
| SNX11 | sorting nexin 11 | 0.00488619 |
| PAMR1 | peptidase domain containing associated with muscle regeneration 1 | 0.00487627 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 0.0048607 |
| TGFA | transforming growth factor, alpha | 0.0048034 |
| LAMC2 | laminin, gamma 2 | 0.00479495 |
| KLF10 | Kruppel-like factor 10 | 0.0047909 |
| PTHLH | parathyroid hormone-like hormone | 0.00476214 |
| FRMD4B | FERM domain containing 4B | 0.00476111 |
| TMF1 | TATA element modulatory factor 1 | 0.0047606 |
| SGPL1 | sphingosine-1-phosphate lyase 1 | 0.00476017 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00475622 |
| MT1F | metallothionein 1F | 0.00474953 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00473347 |
| AHCY | adenosylhomocysteinase | 0.00473123 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 0.00472944 |
| XBP1 | X-box binding protein 1 | 0.00472522 |
| PDGFC | platelet derived growth factor C | 0.00472405 |
| SFXN3 | sideroflexin 3 | 0.00471666 |
| ECM1 | extracellular matrix protein 1 | 0.00470027 |
| CANT1 | calcium activated nucleotidase 1 | 0.00469863 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.00469385 |
| FAXDC2 | fatty acid hydroxylase domain containing 2 | 0.00469247 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.00469141 |
| TRAK2 | trafficking protein, kinesin binding 2 | 0.00469129 |
| TSPAN1 | tetraspanin 1 | 0.00465712 |
| AREG | amphiregulin | 0.00464222 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.00462164 |
| CST1 | cystatin SN | 0.00460075 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.00459975 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00459227 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00457428 |
| NRIP3 | nuclear receptor interacting protein 3 | 0.00456913 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | 0.00456295 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | 0.00456206 |
| KIF3B | kinesin family member 3B | 0.00455396 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl | 0.00454465 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.00454256 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00454157 |
| C14ORF132 | chromosome 14 open reading frame 132 | 0.00453379 |
| TAC1 | tachykinin, precursor 1 | 0.00453174 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | 0.0045301 |
| DNMBP | dynamin binding protein | 0.00452485 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.00452438 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00452079 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00450754 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.00450678 |
| PTN | pleiotrophin | 0.00449067 |
| TSLIG3A | tRNA splicing ligase complex subunit 3A | 0.00446935 |
| MT1E | metallothionein 1E | 0.00446048 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F | 0.0044577 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 | 0.00445375 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | 0.00445156 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.00444898 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.00444536 |
| NANS | N-acetylneuraminic acid synthase | 0.00443817 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0044265 |
| GRAMD2B | GRAM domain containing 2B | 0.00442506 |
| EDN3 | endothelin 3 | 0.00442417 |
| UROD | uroporphyrinogen decarboxylase | 0.00441373 |
| VLDLR | very low density lipoprotein receptor | 0.00440748 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00439089 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00438988 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.00438441 |
| RAB8B | RAB8B, member RAS oncogene family | 0.00437565 |
| TSPAN31 | tetraspanin 31 | 0.00435893 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | 0.00433174 |
| NEU1 | sialidase 1 (lysosomal sialidase) | 0.00432788 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.00432578 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00431643 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 | 0.00430903 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00430358 |
| MAP2K3 | mitogen-activated protein kinase kinase 3 | 0.00428768 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00428724 |
| PLIN3 | perilipin 3 | 0.00428435 |
| OGA | O-GlcNAcase | 0.00427508 |
| MX1 | MX dynamin-like GTPase 1 | 0.00426863 |
| MT2A | metallothionein 2A | 0.00426509 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.00425701 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00425356 |
| EDNRA | endothelin receptor type A | 0.00423673 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 0.0042347 |
| YPEL5 | yippee-like 5 (Drosophila) | 0.0042289 |
| TNC | tenascin C | 0.00422628 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.00422562 |
| CCN2 | cellular communication network factor 2 | 0.00421596 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00420995 |
| IGF1R | insulin-like growth factor 1 receptor | 0.00420919 |
| KARS1 | lysyl-tRNA synthetase 1 | 0.00420689 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00420368 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.00420157 |
| RUNX1 | runt-related transcription factor 1 | 0.00419219 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.00418975 |
| LITAF | lipopolysaccharide-induced TNF factor | 0.00418639 |
| GSTZ1 | glutathione S-transferase zeta 1 | 0.00418245 |
| FLT3 | fms-related tyrosine kinase 3 | 0.00417899 |
| ZNF3 | zinc finger protein 3 | 0.00417295 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 | 0.00417093 |
| DUSP6 | dual specificity phosphatase 6 | 0.00416618 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00415651 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00415488 |
| MCOLN1 | mucolipin 1 | 0.00414557 |
| TEX10 | testis expressed 10 | 0.00414074 |
| SLC35F2 | solute carrier family 35, member F2 | 0.00413148 |
| MLH1 | mutL homolog 1 | 0.00413045 |
| PRKCA | protein kinase C, alpha | 0.00412856 |
| FHL2 | four and a half LIM domains 2 | 0.0041245 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.00412255 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00411207 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.00411056 |
| PWP1 | PWP1 homolog (S. cerevisiae) | 0.00411024 |
| IRF9 | interferon regulatory factor 9 | 0.00410531 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.00410098 |
| PLLP | plasmolipin | 0.00409062 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.00408874 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.00408373 |
| ZNF23 | zinc finger protein 23 | 0.00408338 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00407995 |
| TRIP4 | thyroid hormone receptor interactor 4 | 0.00407969 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.00407386 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | 0.00404966 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.00404822 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.00404064 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00403916 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00403721 |
| TSPAN3 | tetraspanin 3 | 0.00403511 |
| KIAA0226L | KIAA0226-like | 0.00403425 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | 0.00403364 |
| LETMD1 | LETM1 domain containing 1 | 0.00402236 |
| SRPRB | signal recognition particle receptor, B subunit | 0.00402189 |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component | 0.00402053 |
| ARCN1 | archain 1 | 0.00401959 |
| BUD31 | BUD31 homolog (S. cerevisiae) | 0.00401882 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00401767 |
| FOXG1 | forkhead box G1 | 0.00401681 |
| ZDHHC7 | zinc finger, DHHC-type containing 7 | 0.00401506 |
| PRPF4 | pre-mRNA processing factor 4 | 0.0040145 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0040118 |
| VWA5A | von Willebrand factor A domain containing 5A | 0.00401131 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | 0.0040094 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00400738 |
| MALT1 | MALT1 paracaspase | 0.0040068 |
| ZNF394 | zinc finger protein 394 | 0.00399979 |
| MARCH3 | membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase | 0.00399589 |
| BSDC1 | BSD domain containing 1 | 0.00399265 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.00397915 |
| CD9 | CD9 molecule | 0.00397805 |
| RAI14 | retinoic acid induced 14 | 0.00397499 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.00396829 |
| FGFR4 | fibroblast growth factor receptor 4 | 0.00396784 |
| ABHD4 | abhydrolase domain containing 4 | 0.00396768 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00396498 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | -0.0112474 |
| PMP22 | peripheral myelin protein 22 | -0.0104034 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.00976734 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00975839 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00965213 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0092139 |
| KIF14 | kinesin family member 14 | -0.00902076 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00861416 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00834037 |
| CLEC2B | C-type lectin domain family 2, member B | -0.00822488 |
| JCHAIN | joining chain of multimeric IgA and IgM | -0.00814794 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00804514 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00800911 |
| ORC1 | origin recognition complex, subunit 1 | -0.00774294 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00771232 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | -0.00767897 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00748637 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00730445 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.00726575 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00703195 |
| CCDC92 | coiled-coil domain containing 92 | -0.00702242 |
| CPE | carboxypeptidase E | -0.00701238 |
| CD34 | CD34 molecule | -0.00700605 |
| PLXNC1 | plexin C1 | -0.00692935 |
| DAPK1 | death-associated protein kinase 1 | -0.00685372 |
| NMU | neuromedin U | -0.00679735 |
| CCNB1 | cyclin B1 | -0.00676015 |
| TSPAN13 | tetraspanin 13 | -0.00671619 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00654556 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.00651557 |
| INSIG1 | insulin induced gene 1 | -0.00651374 |
| RBPMS | RNA binding protein with multiple splicing | -0.00650692 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.006463 |
| APOB | apolipoprotein B | -0.00644201 |
| IPO9 | importin 9 | -0.00638239 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00637093 |
| SRP9 | signal recognition particle 9kDa | -0.00622175 |
| SMYD3 | SET and MYND domain containing 3 | -0.00621148 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00618407 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00617588 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.00616856 |
| HHEX | hematopoietically expressed homeobox | -0.0061321 |
| NEK2 | NIMA-related kinase 2 | -0.00603838 |
| S100P | S100 calcium binding protein P | -0.00600866 |
| CENPF | centromere protein F, 350/400kDa | -0.00600856 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | -0.00598402 |
| APOA1 | apolipoprotein A-I | -0.00598217 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00594133 |
| FLNA | filamin A, alpha | -0.0059139 |
| PRKCB | protein kinase C, beta | -0.00591339 |
| FOXF1 | forkhead box F1 | -0.00589996 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.00583712 |
| GNPAT | glyceronephosphate O-acyltransferase | -0.00581677 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00581567 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00579263 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | -0.00577167 |
| REEP1 | receptor accessory protein 1 | -0.00576836 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -0.00574543 |
| APOA2 | apolipoprotein A-II | -0.00574193 |
| KLHL9 | kelch-like family member 9 | -0.00571661 |
| TSPAN6 | tetraspanin 6 | -0.00571572 |
| CD69 | CD69 molecule | -0.00570699 |
| NNMT | nicotinamide N-methyltransferase | -0.00569848 |
| MPC2 | mitochondrial pyruvate carrier 2 | -0.00569066 |
| NPC1 | Niemann-Pick disease, type C1 | -0.005689 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.00567387 |
| RCAN2 | regulator of calcineurin 2 | -0.00567332 |
| DHCR7 | 7-dehydrocholesterol reductase | -0.00566131 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | -0.00559758 |
| FGG | fibrinogen gamma chain | -0.0055972 |
| MRPL9 | mitochondrial ribosomal protein L9 | -0.00558721 |
| FASN | fatty acid synthase | -0.00557512 |
| CALML5 | calmodulin-like 5 | -0.005568 |
| LBR | lamin B receptor | -0.00555946 |
| MOCOS | molybdenum cofactor sulfurase | -0.00555859 |
| CD46 | CD46 molecule, complement regulatory protein | -0.00551718 |
| PLN | phospholamban | -0.00550818 |
| LUM | lumican | -0.00543267 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00542347 |
| HPN | hepsin | -0.00536816 |
| PCP4 | Purkinje cell protein 4 | -0.00536435 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.00536185 |
| FH | fumarate hydratase | -0.00535054 |
| PNN | pinin, desmosome associated protein | -0.00533841 |
| MEIS2 | Meis homeobox 2 | -0.00533577 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00528523 |
| SFN | stratifin | -0.00527266 |
| KIF20A | kinesin family member 20A | -0.00526592 |
| MGAM | maltase-glucoamylase | -0.00525478 |
| LTF | lactotransferrin | -0.00525166 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00522027 |
| PRPF3 | pre-mRNA processing factor 3 | -0.00520895 |
| H1-10 | H1.10 linker histone | -0.00519448 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | -0.00517398 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -0.0051538 |
| GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon | -0.0051508 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00514738 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 | -0.00513927 |
| CACYBP | calcyclin binding protein | -0.00510164 |
| PBK | PDZ binding kinase | -0.00509577 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00506389 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.0050391 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00502696 |
| PDE10A | phosphodiesterase 10A | -0.0050234 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00501822 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.00501553 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 | -0.00499228 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | -0.00499219 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00498642 |
| PDZK1 | PDZ domain containing 1 | -0.00496133 |
| DESI1 | desumoylating isopeptidase 1 | -0.00494119 |
| ZNF423 | zinc finger protein 423 | -0.0049162 |
| ZNF692 | zinc finger protein 692 | -0.00490065 |
| KIF5B | kinesin family member 5B | -0.00490036 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00489685 |
| CLDN1 | claudin 1 | -0.00489062 |
| OPN3 | opsin 3 | -0.00486361 |
| FZD6 | frizzled class receptor 6 | -0.00485807 |
| PALM | paralemmin | -0.00485579 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00483994 |
| PMF1 | polyamine-modulated factor 1 | -0.0048394 |
| FOCAD | focadhesin | -0.00483056 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00480585 |
| TSPAN4 | tetraspanin 4 | -0.00479532 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00478388 |
| CYCS | cytochrome c, somatic | -0.00477816 |
| HOPX | HOP homeobox | -0.00477533 |
| ORM1 | orosomucoid 1 | -0.00476642 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | -0.00476048 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.00475419 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | -0.00475214 |
| KYNU | kynureninase | -0.00474891 |
| MB | myoglobin | -0.00474712 |
| RRAGA | Ras-related GTP binding A | -0.00474613 |
| CALD1 | caldesmon 1 | -0.00471954 |
| CLK2 | CDC-like kinase 2 | -0.00471208 |
| LEPR | leptin receptor | -0.00467306 |
| GLRX2 | glutaredoxin 2 | -0.00466135 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00465888 |
| RFX5 | regulatory factor X, 5 (influences HLA class II expression) | -0.00465532 |
| HP | haptoglobin | -0.00465065 |
| ENAH | enabled homolog (Drosophila) | -0.00464496 |
| AHSG | alpha-2-HS-glycoprotein | -0.00463414 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.00461874 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -0.0046178 |
| CFB | complement factor B | -0.00461703 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00461581 |
| RNF115 | ring finger protein 115 | -0.00459496 |
| RAD51AP1 | RAD51 associated protein 1 | -0.00459277 |
| TRAF5 | TNF receptor-associated factor 5 | -0.00456942 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00456589 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00455742 |
| CLU | clusterin | -0.00454729 |
| NXN | nucleoredoxin | -0.00453941 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00453823 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00453539 |
| CCL8 | chemokine (C-C motif) ligand 8 | -0.00452131 |
| DENND4B | DENN/MADD domain containing 4B | -0.00451629 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.004505 |
| TGFB1 | transforming growth factor, beta 1 | -0.00449819 |
| LRP5 | low density lipoprotein receptor-related protein 5 | -0.00449578 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.00447649 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | -0.00446065 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00444414 |
| S100A2 | S100 calcium binding protein A2 | -0.0044428 |
| SDHC | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | -0.00442774 |
| GPX3 | glutathione peroxidase 3 | -0.00442628 |
| CEP350 | centrosomal protein 350kDa | -0.0044259 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00442564 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.00441836 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.00441824 |
| FOXF2 | forkhead box F2 | -0.00441119 |
| UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 | -0.00440818 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | -0.00440366 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit | -0.00440204 |
| PITX1 | paired-like homeodomain 1 | -0.00439887 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.00439094 |
| CALB2 | calbindin 2 | -0.00436204 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.00435609 |
| ILF2 | interleukin enhancer binding factor 2 | -0.00435269 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00434566 |
| SYNM | synemin, intermediate filament protein | -0.00433854 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00433548 |
| AHR | aryl hydrocarbon receptor | -0.00432527 |
| FOXM1 | forkhead box M1 | -0.00431951 |
| ACKR3 | atypical chemokine receptor 3 | -0.00431002 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.00430553 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | -0.00430215 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | -0.00429402 |
| FBLN1 | fibulin 1 | -0.00428867 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00428368 |
| APOC3 | apolipoprotein C-III | -0.00427506 |
| ITM2A | integral membrane protein 2A | -0.00426758 |
| TMEM14A | transmembrane protein 14A | -0.00426684 |
| RCOR3 | REST corepressor 3 | -0.0042567 |
| UQCRFS1 | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | -0.00425401 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00424552 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -0.00423617 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00423377 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00423354 |
| DUSP12 | dual specificity phosphatase 12 | -0.00423003 |
| MALL | mal, T-cell differentiation protein-like | -0.00422488 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | -0.00421714 |
| PON3 | paraoxonase 3 | -0.00421109 |
| PLPP3 | phospholipid phosphatase 3 | -0.00420439 |
| TLN1 | talin 1 | -0.00420404 |
| KIF23 | kinesin family member 23 | -0.00417218 |
| RNPEP | arginyl aminopeptidase (aminopeptidase B) | -0.00416803 |
| RGS1 | regulator of G-protein signaling 1 | -0.00416564 |
| GPATCH2 | G patch domain containing 2 | -0.00416153 |
| PARP1 | poly (ADP-ribose) polymerase 1 | -0.00415266 |
| OLFM1 | olfactomedin 1 | -0.00413698 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00413634 |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 | -0.00413605 |
| JAG2 | jagged 2 | -0.00413347 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.00413279 |
| OIP5 | Opa interacting protein 5 | -0.0041303 |
| HEATR1 | HEAT repeat containing 1 | -0.00412205 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | -0.00411945 |
| CDCA3 | cell division cycle associated 3 | -0.00411909 |
| ANXA3 | annexin A3 | -0.00410795 |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | -0.00410635 |
| KANK1 | KN motif and ankyrin repeat domains 1 | -0.00410275 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.00409857 |
| RTN2 | reticulon 2 | -0.00409412 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | -0.00408699 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00408147 |
| EGFL7 | EGF-like-domain, multiple 7 | -0.00408101 |
| KRT17 | keratin 17, type I | -0.00405565 |
| KRT16 | keratin 16, type I | -0.00405486 |
| FRZB | frizzled-related protein | -0.00405247 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00405049 |
| BCHE | butyrylcholinesterase | -0.00404511 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | -0.00403883 |
| TTC13 | tetratricopeptide repeat domain 13 | -0.0040319 |
| CNN3 | calponin 3, acidic | -0.00403071 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.00402336 |
| NDN | necdin, melanoma antigen (MAGE) family member | -0.00401591 |
| VWF | von Willebrand factor | -0.00399642 |
| TPD52L1 | tumor protein D52-like 1 | -0.00399437 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.00398276 |
| RGS5 | regulator of G-protein signaling 5 | -0.00397738 |
| HOXA5 | homeobox A5 | -0.00397562 |
| AEBP1 | AE binding protein 1 | -0.00397187 |
| EXO1 | exonuclease 1 | -0.00396577 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00395669 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.00395509 |
| CTSH | cathepsin H | -0.00393517 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00393296 |
