RGCC Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description regulator of cell cycle|This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 28984)
External Link https://ncbi.nlm.nih.gov/gene/28984
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Genes

499 genes differentially expressed following the RGCC gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
KDM5D lysine (K)-specific demethylase 5D 0.0159723
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0147102
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.0130334
TMSB15A thymosin beta 15a 0.0120812
CD99 CD99 molecule 0.0116534
PLN phospholamban 0.0115888
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.0109831
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.0109467
GNAS GNAS complex locus 0.0109087
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.0106105
FABP4 fatty acid binding protein 4, adipocyte 0.0105186
LAMA4 laminin, alpha 4 0.0104282
COL15A1 collagen, type XV, alpha 1 0.0103146
DES desmin 0.00995564
MGP matrix Gla protein 0.00981861
ISG15 ISG15 ubiquitin-like modifier 0.00975953
ARHGAP29 Rho GTPase activating protein 29 0.00967789
LAMP3 lysosomal-associated membrane protein 3 0.00960764
AGR2 anterior gradient 2 0.00952944
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00943915
BTBD3 BTB (POZ) domain containing 3 0.00934287
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.0092726
KIF20A kinesin family member 20A 0.0091402
CD93 CD93 molecule 0.00911029
BST2 bone marrow stromal cell antigen 2 0.00907779
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00890574
MAOA monoamine oxidase A 0.00882366
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00881975
CFB complement factor B 0.00880971
SORBS1 sorbin and SH3 domain containing 1 0.00875414
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00874604
CHRDL1 chordin-like 1 0.00873614
OPHN1 oligophrenin 1 0.00861409
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.00853821
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.0085292
MTUS1 microtubule associated tumor suppressor 1 0.00850795
NID1 nidogen 1 0.00846252
TIMP3 TIMP metallopeptidase inhibitor 3 0.00841339
MECOM MDS1 and EVI1 complex locus 0.00840785
BCHE butyrylcholinesterase 0.00836107
MX1 MX dynamin-like GTPase 1 0.00834629
C3 complement component 3 0.00826937
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00817833
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.00815622
SCD5 stearoyl-CoA desaturase 5 0.00815139
FBLN1 fibulin 1 0.00814249
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.00814101
PBX1 pre-B-cell leukemia homeobox 1 0.00813546
SPARCL1 SPARC-like 1 (hevin) 0.00811106
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00806736
COQ8A coenzyme Q8A 0.00805632
IFI44L interferon-induced protein 44-like 0.00787613
ITGA6 integrin, alpha 6 0.00786256
REEP1 receptor accessory protein 1 0.00776179
S100A8 S100 calcium binding protein A8 0.0077504
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.0077464
MYH11 myosin, heavy chain 11, smooth muscle 0.00767753
WDR7 WD repeat domain 7 0.007636
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.0076231
ADGRF5 adhesion G protein-coupled receptor F5 0.00754568
NRN1 neuritin 1 0.00751707
FXYD3 FXYD domain containing ion transport regulator 3 0.00750592
MFAP4 microfibrillar-associated protein 4 0.00749155
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.0074726
RTN1 reticulon 1 0.0074672
DCLK1 doublecortin-like kinase 1 0.00746603
OLFM4 olfactomedin 4 0.00739083
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00731978
FILIP1L filamin A interacting protein 1-like 0.00726149
MYO5C myosin VC 0.00725446
OLFM1 olfactomedin 1 0.00722099
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 0.00719528
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.00717256
PMP22 peripheral myelin protein 22 0.00716002
A2M alpha-2-macroglobulin 0.00715309
SYBU syntabulin (syntaxin-interacting) 0.00714034
IFI16 interferon, gamma-inducible protein 16 0.00713245
EFNA1 ephrin-A1 0.00708636
CLEC2B C-type lectin domain family 2, member B 0.00708541
FHL1 four and a half LIM domains 1 0.00707248
MEIS2 Meis homeobox 2 0.00705479
COLEC12 collectin sub-family member 12 0.00704027
SLIT2 slit homolog 2 (Drosophila) 0.00703704
LUM lumican 0.00697342
ERBB3 erb-b2 receptor tyrosine kinase 3 0.00696849
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.00696807
IFI44 interferon-induced protein 44 0.00696643
NELL2 NEL-like 2 (chicken) 0.00691754
CALD1 caldesmon 1 0.00691743
IL13RA2 interleukin 13 receptor, alpha 2 0.00683173
PRPF8 pre-mRNA processing factor 8 0.00680077
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00679153
SETBP1 SET binding protein 1 0.00678565
SOX11 SRY (sex determining region Y)-box 11 0.0067795
OSMR oncostatin M receptor 0.00675639
SCARB2 scavenger receptor class B, member 2 0.00674676
NEFH neurofilament, heavy polypeptide 0.00674074
NBEA neurobeachin 0.00668335
MOXD1 monooxygenase, DBH-like 1 0.00666524
PCP4 Purkinje cell protein 4 0.0066623
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.00661595
TNNC1 troponin C type 1 (slow) 0.00656951
IRS1 insulin receptor substrate 1 0.00652508
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 0.00649406
SYNM synemin, intermediate filament protein 0.00640713
CST3 cystatin C 0.0063842
AOC3 amine oxidase, copper containing 3 0.00637348
SVIL supervillin 0.0063656
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.00635248
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.0063241
MX2 MX dynamin-like GTPase 2 0.00630282
LIMCH1 LIM and calponin homology domains 1 0.00628198
PLTP phospholipid transfer protein 0.00627598
CAV1 caveolin 1, caveolae protein, 22kDa 0.00626829
LTF lactotransferrin 0.00626368
FZD6 frizzled class receptor 6 0.00626102
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0062562
PGC progastricsin (pepsinogen C) 0.00621873
CADPS2 Ca++-dependent secretion activator 2 0.00621672
LPAR6 lysophosphatidic acid receptor 6 0.00619824
DYNLL1 dynein, light chain, LC8-type 1 0.00618357
RETREG1 reticulophagy regulator 1 0.00616672
EMP2 epithelial membrane protein 2 0.00615289
TENT5A terminal nucleotidyltransferase 5A 0.00612422
ST18 suppression of tumorigenicity 18, zinc finger 0.00611186
MEOX2 mesenchyme homeobox 2 0.00610061
CCL2 chemokine (C-C motif) ligand 2 0.00609643
TGM2 transglutaminase 2 0.00608275
FLRT3 fibronectin leucine rich transmembrane protein 3 0.00606917
ANOS1 anosmin 1 0.00606532
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.00605149
DCHS1 dachsous cadherin-related 1 0.0060508
CFI complement factor I 0.00604804
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0059976
PRAME preferentially expressed antigen in melanoma 0.00599744
USP18 ubiquitin specific peptidase 18 0.00597975
GUSBP3 glucuronidase, beta pseudogene 3 0.00597387
GUSB glucuronidase, beta 0.00593358
PRRX1 paired related homeobox 1 0.00592142
DCN decorin 0.00589333
CDH5 cadherin 5, type 2 (vascular endothelium) 0.00587961
S100A4 S100 calcium binding protein A4 0.00586686
CD163 CD163 molecule 0.00584698
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00583482
LMAN1 lectin, mannose-binding, 1 0.00583349
TIMP1 TIMP metallopeptidase inhibitor 1 0.00582478
WFDC2 WAP four-disulfide core domain 2 0.00581887
C8ORF4 chromosome 8 open reading frame 4 0.00580821
HSPG2 heparan sulfate proteoglycan 2 0.00580791
C1R complement component 1, r subcomponent 0.0057831
ELP1 elongator acetyltransferase complex subunit 1 0.00578227
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00574799
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 0.00573622
L1CAM L1 cell adhesion molecule 0.00573086
USP9Y ubiquitin specific peptidase 9, Y-linked 0.00572203
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00569359
RELN reelin 0.0056905
PTCH1 patched 1 0.00568257
PDZD2 PDZ domain containing 2 0.00567502
HSPB8 heat shock 22kDa protein 8 0.0056472
RNF144A ring finger protein 144A 0.00562856
CALCA calcitonin-related polypeptide alpha 0.00562806
LAMA2 laminin, alpha 2 0.00562469
ADAMTSL3 ADAMTS-like 3 0.0056185
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.0055592
VWF von Willebrand factor 0.00552426
ASPN asporin 0.00550915
RGS5 regulator of G-protein signaling 5 0.00549845
EHBP1 EH domain binding protein 1 0.00547304
IFITM3 interferon induced transmembrane protein 3 0.00547225
FBXO21 F-box protein 21 0.00546474
F2R coagulation factor II (thrombin) receptor 0.00546157
ARG2 arginase 2 0.00545652
ACADVL acyl-CoA dehydrogenase, very long chain 0.00545006
KANK2 KN motif and ankyrin repeat domains 2 0.00544807
ITPRID2 ITPR interacting domain containing 2 0.0054477
PRDX2 peroxiredoxin 2 0.00544424
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00543264
SPG11 spastic paraplegia 11 (autosomal recessive) 0.00542798
PDGFRL platelet-derived growth factor receptor-like 0.00541411
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00540581
SFRP1 secreted frizzled-related protein 1 0.00539611
SYNGR3 synaptogyrin 3 0.00539512
MANSC1 MANSC domain containing 1 0.0053905
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00538044
IRS2 insulin receptor substrate 2 0.00537575
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.00536665
PTPRM protein tyrosine phosphatase, receptor type, M 0.00532711
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00531867
YBX3 Y box binding protein 3 0.00530949
CTSH cathepsin H 0.00530048
GLUL glutamate-ammonia ligase 0.00530029
STON1 stonin 1 0.00530013
CXCL11 chemokine (C-X-C motif) ligand 11 0.00529992
PLCB4 phospholipase C, beta 4 0.00529342
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 0.00528978
NELL1 NEL-like 1 (chicken) 0.00526959
APOD apolipoprotein D 0.00526034
IFITM1 interferon induced transmembrane protein 1 0.00524644
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.00523925
ZFPM2 zinc finger protein, FOG family member 2 0.00523886
MPZL2 myelin protein zero-like 2 0.00523163
CD302 CD302 molecule 0.00519647
PYGL phosphorylase, glycogen, liver 0.00518879
AQP3 aquaporin 3 (Gill blood group) 0.0051839
NPEPL1 aminopeptidase-like 1 0.00517145
CHD9 chromodomain helicase DNA binding protein 9 0.0051674
STMN2 stathmin 2 0.00516609
CAVIN2 caveolae associated protein 2 0.00513403
CCL14 chemokine (C-C motif) ligand 14 0.00512392
FYCO1 FYVE and coiled-coil domain containing 1 0.00512047
DPT dermatopontin 0.00511419
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.0050964
NLGN4X neuroligin 4, X-linked 0.00508469
TENM1 teneurin transmembrane protein 1 0.00508193
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.00507966
TSPAN7 tetraspanin 7 0.00507877
SAMD4A sterile alpha motif domain containing 4A 0.00506288
EHF ets homologous factor 0.00505697
CD46 CD46 molecule, complement regulatory protein 0.00505678
ADAM23 ADAM metallopeptidase domain 23 0.00505482
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.00504329
TNNC2 troponin C type 2 (fast) 0.00503721
ADAR adenosine deaminase, RNA-specific 0.0050272
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.00501323
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.00501108
CXCL10 chemokine (C-X-C motif) ligand 10 0.00500859
C1ORF56 chromosome 1 open reading frame 56 0.00500834
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00500586
EXPH5 exophilin 5 0.00499482
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00499096
CLIC5 chloride intracellular channel 5 0.00498545
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.0049781
GBP1 guanylate binding protein 1, interferon-inducible 0.00497129
XAF1 XIAP associated factor 1 0.00497127
PUM1 pumilio RNA-binding family member 1 0.0049682
ZBED1 zinc finger, BED-type containing 1 0.00496598
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.00495705
SEPTIN10 septin 10 0.00494623
SP110 SP110 nuclear body protein 0.00494419
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00494334
CXADR coxsackie virus and adenovirus receptor 0.00493238
WWTR1 WW domain containing transcription regulator 1 0.00492684
RUSC1 RUN and SH3 domain containing 1 0.00492647
RAPSN receptor-associated protein of the synapse 0.0049181
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 0.00488577
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00488357
ANKRD10 ankyrin repeat domain 10 0.00488032
IFIH1 interferon induced with helicase C domain 1 0.00487527
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.00486621

decreased expression

Symbol Name Standardized Value
CA2 carbonic anhydrase II -0.0149778
MAMLD1 mastermind-like domain containing 1 -0.0110165
VCAM1 vascular cell adhesion molecule 1 -0.0104443
AOC1 amine oxidase, copper containing 1 -0.0102023
BAMBI BMP and activin membrane-bound inhibitor -0.00979108
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.00969924
RCAN1 regulator of calcineurin 1 -0.00959663
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) -0.00953796
INHBA inhibin, beta A -0.00947384
GLIPR1 GLI pathogenesis-related 1 -0.00923224
SMC1A structural maintenance of chromosomes 1A -0.00903218
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) -0.0090029
E2F2 E2F transcription factor 2 -0.00891245
COG7 component of oligomeric golgi complex 7 -0.00888632
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00886174
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00880643
JMJD6 jumonji domain containing 6 -0.00880361
HTRA1 HtrA serine peptidase 1 -0.00879994
ADM adrenomedullin -0.00878995
CLTB clathrin, light chain B -0.00868677
ALCAM activated leukocyte cell adhesion molecule -0.00866974
BCL2A1 BCL2-related protein A1 -0.00848381
HBD hemoglobin, delta -0.00844151
SLC38A1 solute carrier family 38, member 1 -0.0083155
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -0.00825588
SIRT3 sirtuin 3 -0.00821785
LGALS3 lectin, galactoside-binding, soluble, 3 -0.00818226
BPGM 2,3-bisphosphoglycerate mutase -0.00806459
GLDC glycine dehydrogenase (decarboxylating) -0.00798318
ARG1 arginase 1 -0.00795287
KRT14 keratin 14, type I -0.0078925
TUBB2A tubulin, beta 2A class IIa -0.00785955
PUF60 poly-U binding splicing factor 60KDa -0.00779566
RBM34 RNA binding motif protein 34 -0.00773731
KRT7 keratin 7, type II -0.00771412
GPR137B G protein-coupled receptor 137B -0.00770369
CAPG capping protein (actin filament), gelsolin-like -0.00765767
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.0075542
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00748253
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 -0.00720598
SCRG1 stimulator of chondrogenesis 1 -0.00720454
ALAS2 5'-aminolevulinate synthase 2 -0.00718507
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.00716373
F3 coagulation factor III (thromboplastin, tissue factor) -0.00708369
HACD2 3-hydroxyacyl-CoA dehydratase 2 -0.00704795
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00701982
OXTR oxytocin receptor -0.00700971
FTH1 ferritin, heavy polypeptide 1 -0.00696053
XIC X chromosome inactivation center -0.00691302
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.00683035
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 -0.0068021
DLK1 delta-like 1 homolog (Drosophila) -0.0067572
GLUD1 glutamate dehydrogenase 1 -0.00673576
TCL1A T-cell leukemia/lymphoma 1A -0.00667591
AREG amphiregulin -0.00664873
MAP7 microtubule-associated protein 7 -0.00664664
COL11A1 collagen, type XI, alpha 1 -0.0066412
GLS glutaminase -0.00660395
CD59 CD59 molecule, complement regulatory protein -0.00653552
PCOLCE2 procollagen C-endopeptidase enhancer 2 -0.0065302
FXYD2 FXYD domain containing ion transport regulator 2 -0.00652869
TSLIG3A tRNA splicing ligase complex subunit 3A -0.00652321
NPR3 natriuretic peptide receptor 3 -0.00650128
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00648891
CTSD cathepsin D -0.00640432
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -0.00637465
PPIF peptidylprolyl isomerase F -0.00633905
PF4 platelet factor 4 -0.00633651
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00633559
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 -0.00631128
EIF5A eukaryotic translation initiation factor 5A -0.00630127
STC2 stanniocalcin 2 -0.00626995
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00624621
CALB1 calbindin 1, 28kDa -0.00624039
VCAN versican -0.00622231
TSPAN5 tetraspanin 5 -0.00619517
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00616945
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.0061186
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.00611307
THBS1 thrombospondin 1 -0.00609714
LAMC2 laminin, gamma 2 -0.0060879
FOXG1 forkhead box G1 -0.00607008
VEGFC vascular endothelial growth factor C -0.00605219
SDC4 syndecan 4 -0.00603797
EIF4E2 eukaryotic translation initiation factor 4E family member 2 -0.00602524
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.00601872
SCGB2A2 secretoglobin, family 2A, member 2 -0.00599798
ATP8B4 ATPase, class I, type 8B, member 4 -0.00599271
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.00599115
TRIM29 tripartite motif containing 29 -0.00598471
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 -0.00597045
SIK1 salt-inducible kinase 1 -0.0059657
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.00595917
CLIC3 chloride intracellular channel 3 -0.00593154
CGA glycoprotein hormones, alpha polypeptide -0.00592517
CLEC2D C-type lectin domain family 2, member D -0.00588964
STXBP2 syntaxin binding protein 2 -0.0058896
GJA1 gap junction protein, alpha 1, 43kDa -0.00588797
MXRA7 matrix-remodelling associated 7 -0.00586611
PCNA proliferating cell nuclear antigen -0.00585657
FOLR1 folate receptor 1 (adult) -0.00579455
UPP1 uridine phosphorylase 1 -0.0057833
SATB2 SATB homeobox 2 -0.00577921
EFHD1 EF-hand domain family, member D1 -0.0057769
BOP1 block of proliferation 1 -0.0057511
PPP1R16B protein phosphatase 1, regulatory subunit 16B -0.00574759
HAL histidine ammonia-lyase -0.00570167
ZDHHC6 zinc finger, DHHC-type containing 6 -0.00566085
MGAM maltase-glucoamylase -0.00565932
LSP1 lymphocyte-specific protein 1 -0.00564086
ACAN aggrecan -0.00563197
PITX3 paired-like homeodomain 3 -0.00561766
GPR183 G protein-coupled receptor 183 -0.00560766
RRAGD Ras-related GTP binding D -0.00560361
KRT23 keratin 23, type I -0.00558265
EREG epiregulin -0.00557125
TARP TCR gamma alternate reading frame protein -0.00557052
FGFR3 fibroblast growth factor receptor 3 -0.0055677
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -0.00553322
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -0.00552332
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.00547733
MFAP3L microfibrillar-associated protein 3-like -0.00544214
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) -0.00544027
HIST1H2AC histone cluster 1, H2ac -0.00535144
CLDN8 claudin 8 -0.00535128
KRT8 keratin 8, type II -0.00532903
TCEA1 transcription elongation factor A (SII), 1 -0.00531277
SLIRP SRA stem-loop interacting RNA binding protein -0.00525449
SMCO4 single-pass membrane protein with coiled-coil domains 4 -0.00523731
DOCK10 dedicator of cytokinesis 10 -0.00522635
AK4 adenylate kinase 4 -0.00521618
THY1 Thy-1 cell surface antigen -0.0052135
SPATS2L spermatogenesis associated, serine-rich 2-like -0.0052024
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -0.00519763
ZNF586 zinc finger protein 586 -0.00518993
MCM4 minichromosome maintenance complex component 4 -0.00518598
IL33R interleukin 33 receptor -0.00517715
LOXL2 lysyl oxidase-like 2 -0.0051761
ARNTL aryl hydrocarbon receptor nuclear translocator-like -0.00512417
XPO7 exportin 7 -0.00511626
VNN1 vanin 1 -0.00511008
TREM1 triggering receptor expressed on myeloid cells 1 -0.00510579
COMMD9 COMM domain containing 9 -0.00509173
CRYAB crystallin, alpha B -0.00508046
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.00505747
GRAMD2B GRAM domain containing 2B -0.00504968
MICB MHC class I polypeptide-related sequence B -0.00503308
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -0.00502795
SERHL2 serine hydrolase-like 2 -0.00502631
ANPEP alanyl (membrane) aminopeptidase -0.00502477
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -0.00499959
STK17A serine/threonine kinase 17a -0.00499671
ADGRE1 adhesion G protein-coupled receptor E1 -0.00496805
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 -0.00496291
PRSS8 protease, serine, 8 -0.00496171
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -0.00495956
IKZF1 IKAROS family zinc finger 1 (Ikaros) -0.00495764
COMP cartilage oligomeric matrix protein -0.0049566
CYRIB CYFIP related Rac1 interactor B -0.00495307
KLF10 Kruppel-like factor 10 -0.00494697
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00494594
BHMT betaine--homocysteine S-methyltransferase -0.0049241
KRT5 keratin 5, type II -0.00491636
CHMP6 charged multivesicular body protein 6 -0.00491631
DCTN5 dynactin 5 (p25) -0.00489908
DSE dermatan sulfate epimerase -0.00488837
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -0.00487436
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -0.00487392
SKAP2 src kinase associated phosphoprotein 2 -0.0048712
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 -0.00486352
CCNA1 cyclin A1 -0.00485583
FAM162A family with sequence similarity 162, member A -0.00484576
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.00483565
CYTIP cytohesin 1 interacting protein -0.00482485
DSP desmoplakin -0.00482246
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -0.00481283
COL2A1 collagen, type II, alpha 1 -0.00480813
LITAF lipopolysaccharide-induced TNF factor -0.00480655
WIF1 WNT inhibitory factor 1 -0.00480409
ABAT 4-aminobutyrate aminotransferase -0.00479999
PKM pyruvate kinase, muscle -0.00479851
NPC2 Niemann-Pick disease, type C2 -0.00479543
AHSP alpha hemoglobin stabilizing protein -0.00479233
EXOSC4 exosome component 4 -0.00477861
GPX1 glutathione peroxidase 1 -0.00477292
PLK1 polo-like kinase 1 -0.0047722
RORA RAR-related orphan receptor A -0.00476388
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.00475903
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -0.00475299
RGS4 regulator of G-protein signaling 4 -0.0047527
CRIP1 cysteine-rich protein 1 (intestinal) -0.00474924
GDF3 growth differentiation factor 3 -0.00474584
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -0.00473313
NGRN neugrin, neurite outgrowth associated -0.00471894
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.00470659
UQCRH ubiquinol-cytochrome c reductase hinge protein -0.00469102
ELOVL1 ELOVL fatty acid elongase 1 -0.00468912
ACAA2 acetyl-CoA acyltransferase 2 -0.00468881
MT1F metallothionein 1F -0.00468093
HILPDA hypoxia inducible lipid droplet-associated -0.0046632
CRIPT cysteine-rich PDZ-binding protein -0.00464592
EHD1 EH-domain containing 1 -0.0046456
OAT ornithine aminotransferase -0.00461291
RAB29 RAB29, member RAS oncogene family -0.00461209
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00460184
TMEM9B TMEM9 domain family, member B -0.00459801
TM9SF3 transmembrane 9 superfamily member 3 -0.00458692
SCGB1D2 secretoglobin, family 1D, member 2 -0.00455338
SCGB2A1 secretoglobin, family 2A, member 1 -0.00453967
BFAR bifunctional apoptosis regulator -0.0045303
CCL4 chemokine (C-C motif) ligand 4 -0.00453008
ENO1 enolase 1, (alpha) -0.00452189
FOXC1 forkhead box C1 -0.00451
FGB fibrinogen beta chain -0.00450246
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 -0.00450074
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) -0.00449446
GUCY2C guanylate cyclase 2C -0.0044925
MCTP1 multiple C2 domains, transmembrane 1 -0.00448851
RGS2 regulator of G-protein signaling 2 -0.00446602
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.00446472
GPR88 G protein-coupled receptor 88 -0.0044615
SLCO4C1 solute carrier organic anion transporter family, member 4C1 -0.00445573
IFRD1 interferon-related developmental regulator 1 -0.00445553
EIF3H eukaryotic translation initiation factor 3, subunit H -0.00445024
ADD3 adducin 3 (gamma) -0.00444795
GDI2 GDP dissociation inhibitor 2 -0.00444072
SLC26A3 solute carrier family 26 (anion exchanger), member 3 -0.00443556
GNLY granulysin -0.00443457
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.00442481
BANF1 barrier to autointegration factor 1 -0.00441926
WDR41 WD repeat domain 41 -0.004419
STAT4 signal transducer and activator of transcription 4 -0.00441858
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -0.0043984
CCKBR cholecystokinin B receptor -0.00438706
COPE coatomer protein complex, subunit epsilon -0.00436525
RBM47 RNA binding motif protein 47 -0.004365
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00435818
TPK1 thiamin pyrophosphokinase 1 -0.00435605
LYRM1 LYR motif containing 1 -0.0043515
EPHB2 EPH receptor B2 -0.00434836
RIDA reactive intermediate imine deaminase A homolog -0.00434487
PPME1 protein phosphatase methylesterase 1 -0.00434271
JPT2 Jupiter microtubule associated homolog 2 -0.00432263
SPTAN1 spectrin, alpha, non-erythrocytic 1 -0.00431588
MARCKS myristoylated alanine-rich protein kinase C substrate -0.00430765
BST1 bone marrow stromal cell antigen 1 -0.00429802
USH1C Usher syndrome 1C (autosomal recessive, severe) -0.00429531
CAST calpastatin -0.00429336
CST7 cystatin F (leukocystatin) -0.00428634