RGS2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description regulator of G-protein signaling 2|Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis. [provided by RefSeq, Aug 2009] (NCBI Entrez Gene Database, 5997)
External Link http://www.ncbi.nlm.nih.gov/gene/5997
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66 interacting proteins for RGS2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ADCY5 adenylate cyclase 5
ADRA1A adrenoceptor alpha 1A
ADRB2 adrenoceptor beta 2, surface
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
BBS10 Bardet-Biedl syndrome 10
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CEP126 centrosomal protein 126kDa
CHD3 chromodomain helicase DNA binding protein 3
CLTA clathrin, light chain A
COMT catechol-O-methyltransferase
COPB1 coatomer protein complex, subunit beta 1
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
CRMP1 collapsin response mediator protein 1
CTSB cathepsin B
DDR1 discoidin domain receptor tyrosine kinase 1
DUSP21 dual specificity phosphatase 21
DYNLL1 dynein, light chain, LC8-type 1
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3L eukaryotic translation initiation factor 3, subunit L
FZD5 frizzled class receptor 5
GDE1 glycerophosphodiester phosphodiesterase 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNAS GNAS complex locus
HAUS5 HAUS augmin-like complex, subunit 5
HSPA8 heat shock 70kDa protein 8
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IER3IP1 immediate early response 3 interacting protein 1
KLK8 kallikrein-related peptidase 8
LIG1 ligase I, DNA, ATP-dependent
LRFN1 leucine rich repeat and fibronectin type III domain containing 1
METTL18 methyltransferase like 18
MON1A MON1 secretory trafficking family member A
NINL ninein-like
NIPSNAP1 nipsnap homolog 1 (C. elegans)
PARK2 parkin RBR E3 ubiquitin protein ligase
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCG protein kinase C, gamma
PRKCSH protein kinase C substrate 80K-H
PRKG1 protein kinase, cGMP-dependent, type I
RAB2A RAB2A, member RAS oncogene family
RABAC1 Rab acceptor 1 (prenylated)
RAP1B RAP1B, member of RAS oncogene family
REEP5 receptor accessory protein 5
RIN3 Ras and Rab interactor 3
SCN5A sodium channel, voltage gated, type V alpha subunit
TSPAN15 tetraspanin 15
TUBB2B tubulin, beta 2B class IIb
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBC ubiquitin C
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae)
WDR74 WD repeat domain 74
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZBTB48 zinc finger and BTB domain containing 48
ZNF579 zinc finger protein 579
ZYX zyxin