| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | regulator of G-protein signaling 4|Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5999) |
| External Link | https://ncbi.nlm.nih.gov/gene/5999 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the RGS4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.0135778 |
| CA2 | carbonic anhydrase II | 0.0135239 |
| PCNA | proliferating cell nuclear antigen | 0.012651 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.0120476 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.011764 |
| LYZ | lysozyme | 0.0114718 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.011192 |
| SPON1 | spondin 1, extracellular matrix protein | 0.0111841 |
| STK10 | serine/threonine kinase 10 | 0.0110775 |
| CSTA | cystatin A (stefin A) | 0.0106083 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.010402 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.00990412 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.009322 |
| ADD3 | adducin 3 (gamma) | 0.00915566 |
| PEG3 | paternally expressed 3 | 0.00913152 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00910299 |
| CDC42 | cell division cycle 42 | 0.0090292 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00886542 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 0.00876573 |
| MYRF | myelin regulatory factor | 0.00854612 |
| PITX1 | paired-like homeodomain 1 | 0.00851822 |
| THBS1 | thrombospondin 1 | 0.00845931 |
| AK4 | adenylate kinase 4 | 0.00843898 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00822628 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.00817191 |
| SAMHD1 | SAM domain and HD domain 1 | 0.00804195 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 0.00798587 |
| COG7 | component of oligomeric golgi complex 7 | 0.00797019 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00794793 |
| SLC44A4 | solute carrier family 44, member 4 | 0.00790044 |
| C7 | complement component 7 | 0.00788147 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00780304 |
| RRM2 | ribonucleotide reductase M2 | 0.00777356 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00774736 |
| GUCY2C | guanylate cyclase 2C | 0.00769632 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.00769483 |
| MMP10 | matrix metallopeptidase 10 | 0.00762346 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | 0.00760532 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00752694 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00750232 |
| RAB4A | RAB4A, member RAS oncogene family | 0.00747013 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | 0.00744614 |
| SLC25A46 | solute carrier family 25, member 46 | 0.00736022 |
| THY1 | Thy-1 cell surface antigen | 0.00733499 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | 0.00733099 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 0.007307 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.00728063 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00722288 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00721363 |
| CDC45 | cell division cycle 45 | 0.00717918 |
| KRT19 | keratin 19, type I | 0.00717235 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.00716738 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00716292 |
| CCNB2 | cyclin B2 | 0.00715901 |
| THBS2 | thrombospondin 2 | 0.00713732 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00712381 |
| ACKR3 | atypical chemokine receptor 3 | 0.00709067 |
| ASRGL1 | asparaginase like 1 | 0.00707219 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | 0.00703486 |
| NLRP2 | NLR family, pyrin domain containing 2 | 0.00697493 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.00692703 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.00689451 |
| METTL7A | methyltransferase like 7A | 0.0068506 |
| SRSF7 | serine/arginine-rich splicing factor 7 | 0.00684142 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.00683953 |
| SST | somatostatin | 0.0067893 |
| TFF1 | trefoil factor 1 | 0.0067797 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00672373 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | 0.00668054 |
| KIF20A | kinesin family member 20A | 0.00666617 |
| SET | SET nuclear proto-oncogene | 0.0066575 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.00659311 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00656817 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.00653527 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | 0.00652387 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | 0.00649707 |
| RANBP1 | RAN binding protein 1 | 0.00648807 |
| MUC16 | mucin 16, cell surface associated | 0.00644974 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00642855 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00641601 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00639354 |
| TK1 | thymidine kinase 1, soluble | 0.00637256 |
| LTA4H | leukotriene A4 hydrolase | 0.00635464 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00628693 |
| RPS5 | ribosomal protein S5 | 0.00627449 |
| SDC1 | syndecan 1 | 0.00627169 |
| PODXL | podocalyxin-like | 0.00626197 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00624829 |
| LOXL1 | lysyl oxidase-like 1 | 0.00623194 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.00610771 |
| FOXG1 | forkhead box G1 | 0.00607912 |
| RCAN2 | regulator of calcineurin 2 | 0.00606949 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.00601328 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.00599666 |
| MGAM | maltase-glucoamylase | 0.00597781 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00597227 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 0.00596865 |
| TDP1 | tyrosyl-DNA phosphodiesterase 1 | 0.00595395 |
| GCH1 | GTP cyclohydrolase 1 | 0.00594248 |
| TRMT5 | tRNA methyltransferase 5 | 0.00593802 |
| MN1 | meningioma (disrupted in balanced translocation) 1 | 0.00593771 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.00593215 |
| TMEM45A | transmembrane protein 45A | 0.00592918 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.00592238 |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 | 0.00591377 |
| TCF21 | transcription factor 21 | 0.00588617 |
| SULF1 | sulfatase 1 | 0.00587428 |
| TADA2A | transcriptional adaptor 2A | 0.00584956 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.0058474 |
| VNN1 | vanin 1 | 0.00583467 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00583242 |
| RPA2 | replication protein A2, 32kDa | 0.00582269 |
| OCRL | oculocerebrorenal syndrome of Lowe | 0.00581679 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00581478 |
| PLPBP | pyridoxal phosphate binding protein | 0.00581302 |
| B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) | 0.00579 |
| PRTN3 | proteinase 3 | 0.00578945 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | 0.00577963 |
| GDI2 | GDP dissociation inhibitor 2 | 0.00577847 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00577436 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | 0.00577249 |
| NCALD | neurocalcin delta | 0.00576603 |
| PLBD1 | phospholipase B domain containing 1 | 0.00572451 |
| PCTP | phosphatidylcholine transfer protein | 0.00571863 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.00570567 |
| ELANE | elastase, neutrophil expressed | 0.00569346 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | 0.00569317 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 0.00569131 |
| PLN | phospholamban | 0.00568548 |
| CPE | carboxypeptidase E | 0.00567727 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0056592 |
| CD1D | CD1d molecule | 0.00565378 |
| NREP | neuronal regeneration related protein | 0.00564114 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 | 0.00562604 |
| FBL | fibrillarin | 0.00562111 |
| MCAM | melanoma cell adhesion molecule | 0.00559378 |
| ISOC1 | isochorismatase domain containing 1 | 0.0055917 |
| CRIP2 | cysteine-rich protein 2 | 0.00558323 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.00554903 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.00554611 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.00554216 |
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.00554021 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | 0.00553337 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00553208 |
| HYOU1 | hypoxia up-regulated 1 | 0.00549961 |
| UVRAG | UV radiation resistance associated | 0.0054823 |
| H1-10 | H1.10 linker histone | 0.00548193 |
| GSTA1 | glutathione S-transferase alpha 1 | 0.00547979 |
| RNASEH2A | ribonuclease H2, subunit A | 0.00546067 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00545869 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00543065 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0054217 |
| VCAN | versican | 0.00542161 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.00541315 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00540828 |
| ACTN1 | actinin, alpha 1 | 0.00540692 |
| ZNF204P | zinc finger protein 204, pseudogene | 0.00538672 |
| DAXX | death-domain associated protein | 0.00538495 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.00538205 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00538173 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 0.00537638 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.00535879 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.00534478 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | 0.00533419 |
| IRF8 | interferon regulatory factor 8 | 0.00533327 |
| CCNA2 | cyclin A2 | 0.0053298 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00532554 |
| ATP11B | ATPase, class VI, type 11B | 0.00531231 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 0.00529778 |
| MED22 | mediator complex subunit 22 | 0.00528762 |
| LMNB1 | lamin B1 | 0.00527648 |
| HSPA8 | heat shock 70kDa protein 8 | 0.00525947 |
| C2CD5 | C2 calcium-dependent domain containing 5 | 0.00525268 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | 0.00525155 |
| GLO1 | glyoxalase I | 0.00524325 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.00524175 |
| CP | ceruloplasmin (ferroxidase) | 0.00523098 |
| NAGK | N-acetylglucosamine kinase | 0.00522131 |
| BZW2 | basic leucine zipper and W2 domains 2 | 0.0052182 |
| RHOA | ras homolog family member A | 0.00520754 |
| THAP12 | THAP domain containing 12 | 0.00520643 |
| HOXB2 | homeobox B2 | 0.00519773 |
| LPAR6 | lysophosphatidic acid receptor 6 | 0.00518844 |
| DGKZ | diacylglycerol kinase, zeta | 0.00517552 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00515538 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | 0.00514955 |
| ZNF395 | zinc finger protein 395 | 0.00514717 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00514164 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00514129 |
| SUSD4 | sushi domain containing 4 | 0.00513957 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00512142 |
| ACTA2 | actin, alpha 2, smooth muscle, aorta | 0.00510965 |
| COL10A1 | collagen, type X, alpha 1 | 0.00510819 |
| CFD | complement factor D (adipsin) | 0.00510355 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.00509847 |
| CLCA2 | chloride channel accessory 2 | 0.00509184 |
| MRPL19 | mitochondrial ribosomal protein L19 | 0.00508361 |
| EPYC | epiphycan | 0.00508213 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 0.00507787 |
| BST1 | bone marrow stromal cell antigen 1 | 0.00507458 |
| EPHA1 | EPH receptor A1 | 0.00507244 |
| COLEC11 | collectin sub-family member 11 | 0.00506633 |
| ISYNA1 | inositol-3-phosphate synthase 1 | 0.00504476 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00504294 |
| AEBP1 | AE binding protein 1 | 0.00504199 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00503743 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.0050332 |
| OLFML1 | olfactomedin-like 1 | 0.00502075 |
| PRKCA | protein kinase C, alpha | 0.00501679 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.00501311 |
| PARP1 | poly (ADP-ribose) polymerase 1 | 0.00500113 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.00498826 |
| CHEK2 | checkpoint kinase 2 | 0.00497144 |
| IL10RB | interleukin 10 receptor, beta | 0.004968 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 | 0.00496707 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00496705 |
| PER3 | period circadian clock 3 | 0.00496136 |
| QRSL1 | glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 | 0.0049568 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.00495593 |
| RESF1 | retroelement silencing factor 1 | 0.00495494 |
| MKKS | McKusick-Kaufman syndrome | 0.00495352 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.00495002 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 0.00494592 |
| SEPTIN11 | septin 11 | 0.00493152 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00493113 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.00492827 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00491533 |
| COMP | cartilage oligomeric matrix protein | 0.00491 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.00490538 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.00489294 |
| WISP2 | WNT1 inducible signaling pathway protein 2 | 0.00488856 |
| FMO1 | flavin containing monooxygenase 1 | 0.00488742 |
| TFDP1 | transcription factor Dp-1 | 0.00488537 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.00487234 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.00487185 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00486641 |
| GANAB | glucosidase, alpha; neutral AB | 0.0048664 |
| TYMS | thymidylate synthetase | 0.00486438 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 0.00484938 |
| LIMA1 | LIM domain and actin binding 1 | 0.00484649 |
| PHACTR4 | phosphatase and actin regulator 4 | 0.0048397 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 0.00483706 |
| NUP37 | nucleoporin 37kDa | 0.00483409 |
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.00483389 |
| PANK2 | pantothenate kinase 2 | 0.00482241 |
| IL16 | interleukin 16 | 0.00481103 |
| SDF2L1 | stromal cell-derived factor 2-like 1 | 0.00480265 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 | 0.00479588 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.00479041 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA1A | heat shock 70kDa protein 1A | -0.0160942 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.0124174 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0120524 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.0115132 |
| HOPX | HOP homeobox | -0.0106359 |
| CD320 | CD320 molecule | -0.010394 |
| AREG | amphiregulin | -0.0103215 |
| CHI3L2 | chitinase 3-like 2 | -0.00992675 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.00978269 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | -0.00955348 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | -0.00940441 |
| HMG20B | high mobility group 20B | -0.00926261 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00907843 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00894551 |
| PCDH9 | protocadherin 9 | -0.00879859 |
| CALCA | calcitonin-related polypeptide alpha | -0.00876927 |
| NKX2-1 | NK2 homeobox 1 | -0.00874761 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | -0.00846219 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00843275 |
| EMP1 | epithelial membrane protein 1 | -0.00833488 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00828419 |
| PCP4 | Purkinje cell protein 4 | -0.00827601 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00818607 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.00815106 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00813642 |
| NAV2 | neuron navigator 2 | -0.00810888 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00791032 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa | -0.00790671 |
| MT1M | metallothionein 1M | -0.00780595 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00777526 |
| CD9 | CD9 molecule | -0.00775094 |
| TG | thyroglobulin | -0.00763719 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.00762443 |
| PERP | PERP, TP53 apoptosis effector | -0.00760198 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00759085 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00757456 |
| SCD5 | stearoyl-CoA desaturase 5 | -0.00756051 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00753185 |
| SLC35G2 | solute carrier family 35, member G2 | -0.00746658 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00746258 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00744273 |
| TRAPPC3 | trafficking protein particle complex 3 | -0.00744245 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.00742266 |
| APOD | apolipoprotein D | -0.00742024 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.00736875 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0072687 |
| MT1X | metallothionein 1X | -0.00725128 |
| ATF3 | activating transcription factor 3 | -0.00720547 |
| CAPG | capping protein (actin filament), gelsolin-like | -0.00717041 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.00716864 |
| SEPTIN10 | septin 10 | -0.00710755 |
| FSTL1 | follistatin-like 1 | -0.00710473 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00709098 |
| PTCH1 | patched 1 | -0.0070612 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.00702498 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00701734 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -0.00699446 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00696595 |
| USP6NL | USP6 N-terminal like | -0.00693981 |
| FAM189A2 | family with sequence similarity 189, member A2 | -0.00693887 |
| MYBPC1 | myosin binding protein C, slow type | -0.00693512 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00689734 |
| MAGEA3 | melanoma antigen family A3 | -0.00688075 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00687873 |
| RNF13 | ring finger protein 13 | -0.00687135 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | -0.00686474 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.00684665 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00682794 |
| STAG2 | stromal antigen 2 | -0.00681498 |
| MERTK | MER proto-oncogene, tyrosine kinase | -0.00680648 |
| A2M | alpha-2-macroglobulin | -0.00677706 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.00676542 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00670942 |
| SYBU | syntabulin (syntaxin-interacting) | -0.00668248 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00666842 |
| PPL | periplakin | -0.00665113 |
| S100A11 | S100 calcium binding protein A11 | -0.00660691 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00660644 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | -0.00658759 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.00655256 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00654298 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.00653188 |
| LRP4 | low density lipoprotein receptor-related protein 4 | -0.00650143 |
| C1S | complement component 1, s subcomponent | -0.00646253 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.00641484 |
| ZBTB16 | zinc finger and BTB domain containing 16 | -0.00640649 |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | -0.00640447 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | -0.00635419 |
| MAOA | monoamine oxidase A | -0.00633527 |
| SASH1 | SAM and SH3 domain containing 1 | -0.00632948 |
| SLAMF1 | signaling lymphocytic activation molecule family member 1 | -0.00629887 |
| AGRN | agrin | -0.00629844 |
| DUSP5 | dual specificity phosphatase 5 | -0.00627185 |
| WDR45 | WD repeat domain 45 | -0.0062706 |
| MTF2 | metal response element binding transcription factor 2 | -0.00623069 |
| TBC1D4 | TBC1 domain family, member 4 | -0.00622498 |
| MVP | major vault protein | -0.00620968 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00619634 |
| SFTPB | surfactant protein B | -0.00618927 |
| SPP1 | secreted phosphoprotein 1 | -0.006171 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.00615977 |
| PFDN4 | prefoldin subunit 4 | -0.00612589 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00609599 |
| RNF19B | ring finger protein 19B | -0.00606377 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00606319 |
| ECM1 | extracellular matrix protein 1 | -0.00605886 |
| CH25H | cholesterol 25-hydroxylase | -0.00604916 |
| ZBTB18 | zinc finger and BTB domain containing 18 | -0.00601604 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 | -0.00600917 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -0.00600192 |
| NEFM | neurofilament, medium polypeptide | -0.00600034 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0059941 |
| RFTN1 | raftlin, lipid raft linker 1 | -0.00598274 |
| KIF5B | kinesin family member 5B | -0.00598177 |
| TCTA | T-cell leukemia translocation altered | -0.00597619 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.00594352 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | -0.00593527 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.00592963 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.00590821 |
| NPY | neuropeptide Y | -0.00590736 |
| CREB5 | cAMP responsive element binding protein 5 | -0.00589643 |
| TSPO | translocator protein (18kDa) | -0.00588737 |
| IER5 | immediate early response 5 | -0.0058689 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00586437 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | -0.00586028 |
| TGFA | transforming growth factor, alpha | -0.00585361 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0058519 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) | -0.00584522 |
| ADRB2 | adrenoceptor beta 2, surface | -0.00579752 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic | -0.00579535 |
| RTN2 | reticulon 2 | -0.00575796 |
| RGS1 | regulator of G-protein signaling 1 | -0.0057355 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.00572636 |
| PLS3 | plastin 3 | -0.00571999 |
| MT1G | metallothionein 1G | -0.00569621 |
| UBB | ubiquitin B | -0.00565548 |
| G6PD | glucose-6-phosphate dehydrogenase | -0.00564426 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | -0.00563233 |
| MGLL | monoglyceride lipase | -0.00562575 |
| USP47 | ubiquitin specific peptidase 47 | -0.00561579 |
| KDM5A | lysine (K)-specific demethylase 5A | -0.0056129 |
| NRCAM | neuronal cell adhesion molecule | -0.00560427 |
| DLG5 | discs, large homolog 5 (Drosophila) | -0.0055914 |
| RND3 | Rho family GTPase 3 | -0.00555637 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0055294 |
| ATXN7 | ataxin 7 | -0.00552387 |
| DOCK9 | dedicator of cytokinesis 9 | -0.00552111 |
| ZNF148 | zinc finger protein 148 | -0.00552077 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 | -0.00551813 |
| AIM2 | absent in melanoma 2 | -0.00551065 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | -0.00550362 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.00550314 |
| SECISBP2L | SECIS binding protein 2-like | -0.00549204 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0054896 |
| IGSF1 | immunoglobulin superfamily, member 1 | -0.00548728 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00548079 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -0.00547882 |
| MMP7 | matrix metallopeptidase 7 | -0.00547772 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00547696 |
| AMOTL2 | angiomotin like 2 | -0.00545138 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.0054469 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.00543172 |
| MT1E | metallothionein 1E | -0.00543059 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | -0.00542547 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00542541 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.00541749 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00539509 |
| KDSR | 3-ketodihydrosphingosine reductase | -0.00537473 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) | -0.00537073 |
| JUNB | jun B proto-oncogene | -0.00536821 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.00536529 |
| TXN | thioredoxin | -0.00535138 |
| TGIF1 | TGFB-induced factor homeobox 1 | -0.00532686 |
| TBX2 | T-box 2 | -0.005323 |
| CXADR | coxsackie virus and adenovirus receptor | -0.00531811 |
| LEPROT | leptin receptor overlapping transcript | -0.00530799 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00529966 |
| ZBTB43 | zinc finger and BTB domain containing 43 | -0.00529855 |
| TSHR | thyroid stimulating hormone receptor | -0.0052954 |
| TNNC1 | troponin C type 1 (slow) | -0.00526907 |
| RCAN1 | regulator of calcineurin 1 | -0.00526815 |
| UBE3C | ubiquitin protein ligase E3C | -0.00526257 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.00525511 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | -0.00524704 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0052423 |
| SORD | sorbitol dehydrogenase | -0.0052392 |
| MED13 | mediator complex subunit 13 | -0.00523367 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00521447 |
| TMEM87A | transmembrane protein 87A | -0.00520807 |
| IL6 | interleukin 6 | -0.00520586 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.00520281 |
| KEAP1 | kelch-like ECH-associated protein 1 | -0.00519326 |
| TENM1 | teneurin transmembrane protein 1 | -0.00519117 |
| SAFB2 | scaffold attachment factor B2 | -0.00517481 |
| RHOB | ras homolog family member B | -0.00514317 |
| TGM2 | transglutaminase 2 | -0.00511113 |
| VGLL4 | vestigial-like family member 4 | -0.00511042 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | -0.00510587 |
| ANKRD11 | ankyrin repeat domain 11 | -0.00509222 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | -0.00508595 |
| NPC1 | Niemann-Pick disease, type C1 | -0.00507325 |
| RBM26 | RNA binding motif protein 26 | -0.00507057 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.00504893 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.00503972 |
| ZNF580 | zinc finger protein 580 | -0.00503769 |
| EGR2 | early growth response 2 | -0.00502501 |
| HMOX1 | heme oxygenase 1 | -0.00501376 |
| FNDC3B | fibronectin type III domain containing 3B | -0.00500869 |
| PAIP1 | poly(A) binding protein interacting protein 1 | -0.00500373 |
| SLC22A18 | solute carrier family 22, member 18 | -0.00500128 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | -0.00499544 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.00499416 |
| ASMTL | acetylserotonin O-methyltransferase-like | -0.00498483 |
| BCAP31 | B-cell receptor-associated protein 31 | -0.00497739 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -0.00496367 |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase | -0.00493018 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00491727 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | -0.00491725 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.00490806 |
| CTSH | cathepsin H | -0.00490722 |
| EGR1 | early growth response 1 | -0.00489392 |
| SERINC1 | serine incorporator 1 | -0.00489211 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | -0.00488691 |
| INSR | insulin receptor | -0.00488475 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.00487695 |
| SYT1 | synaptotagmin I | -0.00486989 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00483008 |
| RASGRP3 | RAS guanyl releasing protein 3 (calcium and DAG-regulated) | -0.00482074 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.00481448 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00481287 |
| MAB21L2 | mab-21-like 2 (C. elegans) | -0.00480473 |
| ELOB | elongin B | -0.00480391 |
| CTH | cystathionine gamma-lyase | -0.00479962 |
| EFNA1 | ephrin-A1 | -0.00479659 |
| MAGEA12 | melanoma antigen family A12 | -0.00477802 |
| BDNF | brain-derived neurotrophic factor | -0.00477439 |
| TUT7 | terminal uridylyl transferase 7 | -0.00477358 |
| MYO6 | myosin VI | -0.00476752 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.00475624 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.00475237 |
| MXRA8 | matrix-remodelling associated 8 | -0.00474578 |
| TAC1 | tachykinin, precursor 1 | -0.00474018 |
| PDLIM4 | PDZ and LIM domain 4 | -0.00473094 |
| FGL1 | fibrinogen-like 1 | -0.00472108 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.00471374 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.00470466 |
| SALL1 | spalt-like transcription factor 1 | -0.00469596 |
| ANGPT1 | angiopoietin 1 | -0.00467757 |
